| 1 | TBR1 |
| Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse. | |
| Kiyama T, Long Y, Chen CK, Whitaker CM, Shay A, Wu H, Badea TC, Mohsenin A, Parker-Thornburg J, Klein WH, Mills SL, Massey SC, Mao CA. | |
| Cell Rep 27(3):900-915.e5. doi: 10.1016/j.celrep.2019.03.077. 2019 | |
| 2 | TBR1 |
| Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice. | |
| Huang TN, Yen TL, Qiu LR, Chuang HC, Lerch JP, Hsueh YP. | |
| Mol Autism 10:5. doi: 10.1186/s13229-019-0257-5. eCollection 2019. 2019 | |
| 3 | IDDAS, TBR1 |
| Functional characterization of TBR1 variants in neurodevelopmental disorder. | |
| den Hoed J, Sollis E, Venselaar H, Estruch SB, Deriziotis P, Fisher SE. | |
| Sci Rep 8(1):14279. doi: 10.1038/s41598-018-32053-6. 2018 | |
| 4 | IDDAS, TBR1 |
| The TBR1-related autistic-spectrum-disorder phenotype and its clinical spectrum. | |
| McDermott JH, Study DDD, Clayton-Smith J, Briggs TA. | |
| Eur J Med Genet 61(5):253-256. doi: 10.1016/j.ejmg.2017.12.009. Epub 2017 Dec 27. 2018 | |
| 5 | IDDAS, TBR1 |
| Mutations in TBR1 gene leads to cortical malformations and intellectual disability. | |
| Vegas N, Cavallin M, Kleefstra T, de Boer L, Philbert M, Maillard C, Boddaert N, Munnich A, Hubert L, Bery A, Besmond C, Bahi-Buisson N. | |
| Eur J Med Genet 61(12):759-764. doi: 10.1016/j.ejmg.2018.09.012. Epub 2018 Sep 27. 2018 | |
| 6 | TBR1 |
| Neonatal Tbr1 Dosage Controls Cortical Layer 6 Connectivity. | |
| Fazel Darbandi S, Robinson Schwartz SE, Qi Q, Catta-Preta R, Pai EL, Mandell JD, Everitt A, Rubin A, Krasnoff RA, Katzman S, Tastad D, Nord AS, Willsey AJ, Chen B, State MW, Sohal VS, Rubenstein JLR. | |
| Neuron 100(4):831-845.e7. doi: 10.1016/j.neuron.2018.09.027. Epub 2018 Oct 11. 2018 | |
| 7 | TBR1 |
| Tbr1 instructs laminar patterning of retinal ganglion cell dendrites. | |
| Liu J, Reggiani JDS, Laboulaye MA, Pandey S, Chen B, Rubenstein JLR, Krishnaswamy A, Sanes JR. | |
| Nat Neurosci 21(5):659-670. doi: 10.1038/s41593-018-0127-z. Epub 2018 Apr 9. 2018 | |
| 8 | CASK, TBR1 |
| Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of associative memory in male mice. | |
| Huang TN, Hsueh YP. | |
| J Psychiatry Neurosci 42(1):37-47. 2017 | |
| 9 | TBR1 |
| TBR1 regulates autism risk genes in the developing neocortex. | |
| Notwell JH, Heavner WE, Darbandi SF, Katzman S, McKenna WL, Ortiz-Londono CF, Tastad D, Eckler MJ, Rubenstein JL, McConnell SK, Chen B, Bejerano G. | |
| Genome Res 26(8):1013-22. doi: 10.1101/gr.203612.115. Epub 2016 Jun 20. 2016 | |
| 10 | TBR1 |
| T-Brain-1--A Potential Master Regulator in Autism Spectrum Disorders. | |
| Chuang HC, Huang TN, Hsueh YP. | |
| Autism Res 8(4):412-26. doi: 10.1002/aur.1456. Epub 2015 Jan 20. 2015 | |
| 11 | IDDAS, TBR1 |
| De novo TBR1 mutations in sporadic autism disrupt protein functions. | |
| Deriziotis P, O'Roak BJ, Graham SA, Estruch SB, Dimitropoulou D, Bernier RA, Gerdts J, Shendure J, Eichler EE, Fisher SE. | |
| Nat Commun 5:4954. doi: 10.1038/ncomms5954. 2014 | |
| 12 | TBR1 |
| Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. | |
| Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP. | |
| Nat Neurosci 17(2):240-7. doi: 10.1038/nn.3626. Epub 2014 Jan 19. 2014 | |
| 13 | FEZF2, TBR1 |
| Tbr1 and Fezf2 regulate alternate corticofugal neuronal identities during neocortical development. | |
| McKenna WL, Betancourt J, Larkin KA, Abrams B, Guo C, Rubenstein JL, Chen B. | |
| J Neurosci 31(2):549-64. 2011 | |
| 14 | FEZF2, TBR1 |
| TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract. | |
| Han W, Kwan KY, Shim S, Lam MM, Shin Y, Xu X, Zhu Y, Li M, Sestan N. | |
| Proc Natl Acad Sci U S A 108(7):3041-6. Epub 2011 Feb 1. 2011 | |
| 15 | AUTS2, TBR1 |
| Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex. | |
| Bedogni F, Hodge RD, Elsen GE, Nelson BR, Daza RA, Beyer RP, Bammler TK, Rubenstein JL, Hevner RF. | |
| Proc Natl Acad Sci U S A 107(29):13129-34. Epub 2010 Jul 6.PMID: 20615956 2010 | |
| 16 | CASK, GPR34, GPR82, MICPCH, RELN, TBR1 |
| An X-linked microcephaly syndrome caused by disruptions of CASK implicates the CASK-TBR1-RELN pathway in human brain development. | |
| Bailey KA, Aldinger KA. | |
| Clin Genet 75(5):424-5. No abstract available. 2009 | |
| 17 | CASK, MICPCH, TBR1 |
| Mutations of CASK cause an X-linked brain malformation phenotype with microcephaly and hypoplasia of the brainstem and cerebellum. | |
| Najm J, Horn D, Wimplinger I, Golden JA, Chizhikov VV, Sudi J, Christian SL, Ullmann R, Kuechler A, Haas CA, Flubacher A, Charnas LR, Uyanik G, Frank U, Klopocki E, Dobyns WB, Kutsche K. | |
| Nat Genet at Genet. 2008 Aug 10. [Epub ahead of print] 2008 | |
| 18 | TBR1 |
| A unique subpopulation of Tbr1-expressing deep layer neurons in the developing cerebral cortex. | |
| Kolk SM, Whitman MC, Yun ME, Shete P, Donoghue MJ. | |
| Mol Cell Neurosci 32(1-2):200-14. 2006 | |
| 19 | ABCB7, AMMECR1, APOOL, ARHGEF9, ARL13A, ASMTL, BMP2KL, CDK5R2, CHIC1, COX7B, CT55, CXorf1, CXorf31, CXorf40A, CXorf58, CXorf59, FTHL19, GAGE12H, GAGE12J, GAGE13, GAGE2C, GAGE2E, GCA, ITM2A, KLHL4, MAGEB1, MBTPS2, MMADHC, MORC4, NOL10, PAGE4, PIH1D3, RAB33A, RAB40AL, SCML1, SMS, SSX10, STRN, TBR1, ZXDB |
| The DNA sequence of the human X chromosome. | |
| Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Glockner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, Muller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR. | |
| Nature 434(7031):325-37. 2005 | |
| 20 | PAX6, TBR1, TBR2 |
| Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. | |
| Englund C, Fink A, Lau C, Pham D, Daza RA, Bulfone A, Kowalczyk T, Hevner RF. | |
| J Neurosci 25(1):247-51. 2005 | |
| 21 | CASK, TBR1 |
| Identification of Tbr-1/CASK complex target genes in neurons. | |
| Wang TF, Ding CN, Wang GS, Luo SC, Lin YL, Ruan Y, Hevner R, Rubenstein JL, Hsueh YP. | |
| J Neurochem 91(6):1483-92. 2004 | |
| 22 | TBR1 |
| T-brain-1: a homolog of Brachyury whose expression defines molecularly distinctdomains within the cerebral cortex. | |
| Bulfone A, Smiga SM, Shimamura K, Peterson A, Puelles L, Rubenstein JL. | |
| Neuron 15(1):63-78. 1995 | |