| 1 | ARL2, TBCD
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| A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and β-Tubulin Is Required for Maintaining the Microtubule Network.
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| Francis JW, Newman LE, Cunningham LA, Kahn RA.
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| J Biol Chem 292(10):4336-4349. doi: 10.1074/jbc.M116.770909. Epub 2017 Jan 26.
2017
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| 2 | PEBAT, TBCD
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| Biallelic TBCD Mutations Cause Early-Onset Neurodegenerative Encephalopathy.
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| Miyake N, Fukai R, Ohba C, Chihara T, Miura M, Shimizu H, Kakita A, Imagawa E, Shiina M, Ogata K, Okuno-Yuguchi J, Fueki N, Ogiso Y, Suzumura H, Watabe Y, Imataka G, Leong HY, Fattal-Valevski A, Kramer U, Miyatake S, Kato M, Okamoto N, Sato Y, Mitsuhashi S, Nishino I, Kaneko N, Nishiyama A, Tamura T, Mizuguchi T, Nakashima M, Tanaka F, Saitsu H, Matsumoto N.
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| Am J Hum Genet 99(4):950-961. doi: 10.1016/j.ajhg.2016.08.005.
2016
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| 3 | PEBAT, TBCD
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| Biallelic Mutations in TBCD, Encoding the Tubulin Folding Cofactor D, Perturb Microtubule Dynamics and Cause Early-Onset Encephalopathy.
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| Flex E, Niceta M, Cecchetti S, Thiffault I, Au MG, Capuano A, Piermarini E, Ivanova AA, Francis JW, Chillemi G, Chandramouli B, Carpentieri G, Haaxma CA, Ciolfi A, Pizzi S, Douglas GV, Levine K, Sferra A, Dentici ML, Pfundt RR, Le Pichon JB, Farrow E, Baas F, Piemonte F, Dallapiccola B, Graham JM Jr, Saunders CJ, Bertini E, Kahn RA, Koolen DA, Tartaglia M.
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| Am J Hum Genet 99(4):962-973. doi: 10.1016/j.ajhg.2016.08.003.
2016
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| 4 | PEBAT, TBCD
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| Microcephaly, intractable seizures and developmental delay caused by biallelic variants in TBCD: Further delineation of a new chaperone-mediated tubulinopathy.
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| Pode-Shakked B, Barash H, Ziv L, Gripp KW, Flex E, Barel O, Carvalho KS, Scavina M, Chillemi G, Niceta M, Eyal E, Kol N, Ben-Zeev B, Bar-Yosef O, Marek-Yagel D, Bertini E, Duker AL, Anikster Y, Tartaglia M, Raas-Rothschild A.
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| Clin Genet lin Genet. 2016 Nov 2. doi: 10.1111/cge.12914. [Epub ahead of print]
2016
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| 5 | PEBAT, TBCD
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| Infantile Neurodegenerative Disorder Associated with Mutations in TBCD, an Essential Gene in the Tubulin Heterodimer Assembly Pathway.
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| Edvardson S, Tian G, Cullen H, Vanyai H, Ngo L, Bhat S, Aran A, Daana M, Da'amseh N, Abu-Libdeh B, Cowan NJ, Heng J, Elpeleg O.
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| Hum Mol Genet um Mol Genet. 2016 Aug 29. pii: ddw292. [Epub ahead of print]
2016
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| 6 | ARL2, ARL3, TBCD
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| Higher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions.
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| Francis JW, Turn RE, Newman LE, Schiavon C, Kahn RA.
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| Small GTPases 7(4):188-196. Epub 2016 Jul 11. Review.
2016
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| 7 | ARL2, TBCD, TBCE
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| Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamics.
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| Nithianantham S, Le S, Seto E, Jia W, Leary J, Corbett KD, Moore JK, Al-Bassam J.
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| Elife 4. doi: 10.7554/eLife.08811.
2015
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| 8 | DSCAM, TBCD
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| Linking cell surface receptors to microtubules: tubulin folding cofactor D mediates Dscam functions during neuronal morphogenesis.
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| Okumura M, Sakuma C, Miura M, Chihara T.
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| J Neurosci 35(5):1979-90. doi: 10.1523/JNEUROSCI.0973-14.2015.
2015
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| 9 | ARL2, TBCD
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| Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity.
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| Tian G, Thomas S, Cowan NJ.
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| Cytoskeleton (Hoboken) 67(11):706-14. doi: 10.1002/cm.20480.
2010
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| 10 | TBCD
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| Cofactor D functions as a centrosomal protein and is required for the recruitment of the gamma-tubulin ring complex at centrosomes and organization of the mitotic spindle.
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| Cunningham LA, Kahn RA.
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| J Biol Chem 283(11):7155-65. Epub 2008 Jan 2. 2008
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| 11 | TBCD, ARL2
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| Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A.
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| Shern JF, Sharer JD, Pallas DC, Bartolini F, Cowan NJ, Reed MS, Pohl J, Kahn RA.
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| J Biol Chem 278(42):40829-36. Epub 2003 Aug 11. 2003
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| 12 | ARF4, TBCD
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| ADP ribosylation factor-like protein 2 (Arl2) regulates the interaction of tubulin-folding cofactor D with native tubulin.
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| Bhamidipati A, Lewis SA, Cowan NJ.
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| J Cell Biol 149(5):1087-96. 2000
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| 13 | TBCD
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| Tubulin folding cofactor D is a microtubule destabilizing protein.
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| Martin L, Fanarraga ML, Aloria K, Zabala JC.
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| FEBS Lett 470(1):93-5. 2000
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| 14 | RP2, TBCA, TBCD, TBCE
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| Pathway leading to correctly folded beta-tubulin.
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| Tian G, Huang Y, Rommelaere H, Vandekerckhove J, Ampe C, Cowan NJ.
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| Cell 86(2):287-96. 1996
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