| 1 | CLDN7, EPCAM, TACSTD2
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| EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice.
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| Szabo R, Ward JM, Artunc F, Bugge TH.
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| Biol Open. ul 15;11(7):bio059403. doi: 10.1242/bio.059403. Epub 2022 Jul 11. 2022
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| 2 | TACSTD2
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| TACSTD2 upregulation is an early reaction to lung infection.
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| Lenárt S, Lenárt P, Knopfová L, Kotasová H, Pelková V, Sedláková V, Vacek O, Pokludová J, Čan V, Šmarda J, Souček K, Hampl A, Beneš P.
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| Sci Rep. Jun 10;12(1):9583. doi: 10.1038/s41598-022-13637-9. 2022
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| 3 | TACSTD2
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| Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer.
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| Guerra E, Trerotola M, Relli V, Lattanzio R, Tripaldi R, Vacca G, Ceci M, Boujnah K, Garbo V, Moschella A, Zappacosta R, Simeone P, de Lange R, Weidle UH, Rotelli MT, Picciariello A, Depalo R, Querzoli P, Pedriali M, Bianchini E, Angelucci D, Pizzicannella G, Di Loreto C, Piantelli M, Antolini L, Sun XF, Altomare DF, Alberti S.
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| Neoplasia Sep;23(9):898-911. doi: 10.1016/j.neo.2021.07.002. Epub 2021 Jul 25. 2021
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| 4 | ADAM10, TACSTD2
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| Trop-2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis.
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| Trerotola M, Guerra E, Ali Z, Aloisi AL, Ceci M, Simeone P, Acciarito A, Zanna P, Vacca G, D'Amore A, Boujnah K, Garbo V, Moschella A, Lattanzio R, Alberti S.
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| Neoplasia. Apr;23(4):415-428. doi: 10.1016/j.neo.2021.03.006. Epub 2021 Apr 8. 2021
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| 5 | TACSTD2
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| Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1
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| Hsu EC, Rice MA, Bermudez A, Marques FJG, Aslan M, Liu S, Ghoochani A, Zhang CA, Chen YS, Zlitni A, Kumar S, Nolley R, Habte F, Shen M, Koul K, Peehl DM, Zoubeidi A, Gambhir SS, Kunder CA, Pitteri SJ, Brooks JD, Stoyanova T.
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| Proc Natl Acad Sci U S A. Jan 28;117(4):2032-2042. doi: 10.1073/pnas.1905384117. Epub 2020 Jan 13. 2020
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| 6 | LGALS3, MUC1, SP1, TACSTD2
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| Induction of Trop-2 expression through the binding of galectin-3 to MUC1.
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| Yamashita T, Mori Y, Alzaaqi SM, Yashiro M, Sawada T, Hirakawa K, Nakada H.
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| Biochem Biophys Res Commun. Aug 13;516(1):44-49. doi: 10.1016/j.bbrc.2019.06.003. Epub 2019 Jun 10. 2019
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| 7 | GDLD, TACSTD2
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| Novel Mutations in TACSTD2 Gene in Families with Gelatinous Drop-like Corneal Dystrophy (GDLD)
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| Alehabib E, Jamshidi J, Ghaedi H, Emamalizadeh B, Andarva M, Daftarian N, Rezaei Kanavi M, Mohammadi Torbati P, Espandar G, Alinaghi S, Johari AH, Saghally M, Mohajerani F, Darvish H
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| Int J Mol Cell Med. Fall;6(4):204-211. doi: 10.22088/BUMS.6.4.204. Epub 2017 Dec 11. 2017
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| 8 | TACSTD2
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| Impact of TROP2 expression on prognosis in solid tumors: A Systematic Review and Meta-analysis.
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| Zeng P, Chen MB, Zhou LN, Tang M, Liu CY, Lu PH.
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| Sci Rep. Sep 20;6:33658. doi: 10.1038/srep33658. 2016
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| 9 | GDLD, TACSTD2
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| Novel TACSTD2 mutation in gelatinous drop-like corneal dystrophy
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| Jongkhajornpong P, Lekhanont K, Ueta M, Kitazawa K, Kawasaki S, Kinoshita S.
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| Hum Genome Var. Nov 26;2:15047. doi: 10.1038/hgv.2015.47. 2015
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| 10 | TACSTD2
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| Loss of TACSTD2 contributed to squamous cell carcinoma progression through attenuating TAp63-dependent apoptosis
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| Wang F, Liu X, Yang P, Guo L, Liu C, Li H, Long S, Shen Y, Wan H.
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| Cell Death Dis. Mar 20;5(3):e1133. doi: 10.1038/cddis.2014.96. 2014
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| 11 | TACSTD2
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| Two novel mutations of TACSTD2 found in three Japanese gelatinous drop-like corneal dystrophy families with their aberrant subcellular localization.
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| Nakatsukasa M, Kawasaki S, Yamasaki K, Fukuoka H, Matsuda A, Nishida K, Kinoshita S.
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| Mol Vis. 17:965-70. 2011
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| 12 | TACSTD2
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| Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway.
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| Cubas R, Zhang S, Li M, Chen C, Yao Q.
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| Mol Cancer 9:253.
2010
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| 13 | GDLD, TACSTD2
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| Identification and characterization of a novel TACSTD2 mutation in gelatinous drop-like corneal dystrophy.
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| Paliwal P, Gupta J, Tandon R, Sharma N, Titiyal JS, Kashyap S, Sen S, Kaur P, Dube D, Sharma A, Vajpayee RB.
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| Mol Vis 16:729-39.
2010
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| 14 | TACSTD2
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| Trop-2 overexpression as an independent marker for poor overall survival in ovarian carcinoma patients.
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| Bignotti E, Todeschini P, Calza S, Falchetti M, Ravanini M, Tassi RA, Ravaggi A, Bandiera E, Romani C, Zanotti L, Tognon G, Odicino FE, Facchetti F, Pecorelli S, Santin AD.
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| Eur J Cancer 46(5):944-53. Epub 2010 Jan 8.
2010
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| 15 | GDLD, TACSTD2
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| A novel TACSTD2 mutation identified in two Chinese brothers with gelatinous drop-like corneal dystrophy.
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| Jing Y, Liu C, Wang L.
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| Mol Vis 15:1580-8.
2009
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| 16 | TACSTD2
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| High expression of TROP2 correlates with poor prognosis in pancreatic cancer.
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| Fong D, Moser P, Krammel C, Gostner JM, Margreiter R, Mitterer M, Gastl G, Spizzo G.
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| Br J Cancer 99(8):1290-5. Epub 2008 Sep 23.
2008
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| 17 | TACSTD2
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| Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers.
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| Wang J, Day R, Dong Y, Weintraub SJ, Michel L.
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| Mol Cancer Ther 7(2):280-5.
2008
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| 18 | EPCAM, GDLD, TACSTD2
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| Phenotypic investigation of cell junction-related proteins in gelatinous drop-like corneal dystrophy.
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| Takaoka M, Nakamura T, Ban Y, Kinoshita S.
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| Invest Ophthalmol Vis Sci 48(3):1095-101. 2007
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| 19 | TACSTD2, GDLD
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| Four mutations (three novel, one founder) in TACSTD2 among Iranian GDLD patients.
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| Alavi A, Elahi E, Tehrani MH, Amoli FA, Javadi MA, Rafati N, Chiani M, Banihosseini SS, Bayat B, Kalhor R, Amini SS.
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| Invest Ophthalmol Vis Sci 48(10):4490-7. 2007
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| 20 | GDLD, TACSTD2
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| A novel TACSTD2 gene mutation in a Turkish family with a gelatinous drop-like corneal dystrophy.
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| Markoff A, Bogdanova N, Uhlig CE, Groppe M, Horst J, Kennerknecht I.
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| Mol Vis 12:1473-6. 2006
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| 21 | TACSTD2
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| Clinical significance of TROP2 expression in colorectal cancer.
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| Ohmachi T, Tanaka F, Mimori K, Inoue H, Yanaga K, Mori M.
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| Clin Cancer Res 12(10):3057-63.
2006
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| 22 | TACSTD2, GDLD
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| Compound heterozygous mutations of M1S1 gene in gelatinous droplike corneal dystrophy.
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| Tian X, Fujiki K, Li Q, Murakami A, Xie P, Kanai A, Wang W, Liu Z.
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| Am J Ophthalmol 137(3):567-9. 2004
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| 23 | C9orf6, TACSTD2
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| Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus.
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| Ahn J, Chung KS, Kim DU, Won M, Kim L, Kim KS, Nam M, Choi SJ, Kim HC, Yoon M, Chae SK, Hoe KL.
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| J Biochem Mol Biol 37(6):741-8. 2004
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| 24 | GDLD, TACSTD2
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| Allelic and locus heterogeneity in autosomal recessive gelatinous drop-like corneal dystrophy.
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| Ren Z, Lin PY, Klintworth GK, Iwata F, Munier FL, Schorderet DF, El Matri L, Theendakara V, Basti S, Reddy M, Hejtmancik JF.
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| Hum Genet 110(6):568-77. 2002
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| 25 | CCND1, TACSTD2
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| Cyclin D1 gene contains a cryptic promoter that is functional in human cancer cells.
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| Terrinoni A, Dell'Arciprete R, Fornaro M, Stella M, Alberti S.
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| Genes Chromosomes Cancer 31(3):209-20. 2001
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| 26 | TACSTD2
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| A novel mutation in the M1S1 gene responsible for gelatinous droplike corneal dystrophy.
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| Tasa G, Kals J, Muru K, Juronen E, Piirsoo A, Veromann S, Janes S, Mikelsaar AV, Lang A.
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| Invest Ophthalmol Vis Sci 42(12):2762-4. 2001
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| 27 | GDLD, TACSTD2
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| Q118X mutation of M1S1 gene caused gelatinous drop-like corneal dystrophy: the P501T of BIGH3 gene found in a family with gelatinous drop-like corneal dystrophy.
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| Ha NT, Fujiki K, Hotta Y, Nakayasu K, Kanai A.
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| Am J Ophthalmol 130(1):119-20. 2000
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| 28 | GDLD, TACSTD2
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| Identification of the gene responsible for gelatinous drop-like corneal dystrophy.
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| Tsujikawa M, et al.
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| Nat Genet 21(4):420-3. 1999
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| 29 | TACSTD2
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| Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas.
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| Fornaro M, Dell'Arciprete R, Stella M, Bucci C, Nutini M, Capri MG, Alberti S.
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| Int J Cancer. 62(5):610-8. 1995
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| 30 | EPCAM, TACSTD2
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| Retroposition in a family of carcinoma-associated antigen genes.
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| Linnenbach AJ, et al.
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| Mol Cell Biol 13 : 1507-1515. 1993
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| 31 | EPCAM, TACSTD2
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| Sequence investigation of the major gastrointestinal tumor-associated antigen gene family, GA733.
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| Linnenbach AJ, et al.
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| Proc Natl Acad Sci U S A 86(1):27-31. 1989
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