| 1 | RAB27A, STXBP1, SYTL4
|
| STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a.
|
| van Breevoort D, Snijders AP, Hellen N, Weckhuysen S, van Hooren KW, Eikenboom J, Valentijn K, Fernandez-Borja M, Ceulemans B, De Jonghe P, Voorberg J, Hannah M, Carter T, Bierings R.
|
| Blood 123(20):3185-94. doi: 10.1182/blood-2013-10-535831.
2014
|
| 2 | RAB27A, SYTL1, SYTL4
|
| The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane.
|
| Wang H, Ishizaki R, Xu J, Kasai K, Kobayashi E, Gomi H, Izumi T.
|
| Mol Biol Cell 24(3):319-30. doi: 10.1091/mbc.E12-04-0265. Epub 2012 Dec 5. 2013
|
| 3 | RAB8A, SYTL1, SYTL4
|
| Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets.
|
| Hampson A, O'Connor A, Smolenski A.
|
| J Thromb Haemost 11(1):161-8. doi: 10.1111/jth.12068.
2013
|
| 4 | STX1A, SYTL4
|
| Loss of granuphilin and loss of syntaxin-1A cause differential effects on insulin granule docking and fusion.
|
| Wang H, Ishizaki R, Kobayashi E, Fujiwara T, Akagawa K, Izumi T.
|
| J Biol Chem 286(37):32244-50. Epub 2011 Jul 18.
2011
|
| 5 | EXPH5, RAB27A, RAB27B, SYTL4
|
| Rab27a and Rab27b control different steps of the exosome secretion pathway.
|
| Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A, Moita CF, Schauer K, Hume AN, Freitas RP, Goud B, Benaroch P, Hacohen N, Fukuda M, Desnos C, Seabra MC, Darchen F, Amigorena S, Moita LF, Thery C.
|
| Nat Cell Biol 12(1):19-30; sup pp 1-13. doi: 10.1038/ncb2000. Epub 2009 Dec 6.
2010
|
| 6 | STXBP1, SYTL4
|
| Munc 18-1 and granuphilin collaborate during insulin granule exocytosis.
|
| Tomas A, Meda P, Regazzi R, Pessin JE, Halban PA.
|
| Traffic 9(5):813-32. Epub 2008 Jan 19.
2008
|
| 7 | SYTL4
|
| MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells.
|
| Plaisance V, Abderrahmani A, Perret-Menoud V, Jacquemin P, Lemaigre F, Regazzi R.
|
| J Biol Chem 281(37):26932-42. Epub 2006 Jul 10.
2006
|
| 8 | SREBF1, SYTL4
|
| Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice.
|
| Kato T, Shimano H, Yamamoto T, Yokoo T, Endo Y, Ishikawa M, Matsuzaka T, Nakagawa Y, Kumadaki S, Yahagi N, Takahashi A, Sone H, Suzuki H, Toyoshima H, Hasty AH, Takahashi S, Gomi H, Izumi T, Yamada N.
|
| Cell Metab 4(2):143-54.
2006
|
| 9 | SYTL4
|
| Slp4-a/granuphilin-a interacts with syntaxin-2/3 in a Munc18-2-dependent manner.
|
| Fukuda M, Imai A, Nashida T, Shimomura H.
|
| J Biol Chem 280(47):39175-84. Epub 2005 Sep 26.
2005
|
| 10 | EXPH5,MLPH,MYRIP,SYTL1,SYTL2,SYTL3,SYTL4,SYTL5
|
| The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.
|
| Kuroda TS, Fukuda M, Ariga H, Mikoshiba K.
|
| J Biol Chem 277(11):9212-8. Epub 2001 Dec 31. 2002
|
| 11 | MLPH,SYTL1,SYTL2,SYTL3,SYTL4
|
| Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: identification of the Slp homology domain.
|
| Fukuda M, Saegusa C, Mikoshiba K.
|
| Biochem Biophys Res Commun 283(2):513-9. 2001
|
| 12 | SYTL4
|
| Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells.
|
| Wang J, Takeuchi T, Yokota H, Izumi T.
|
| J Biol Chem 274(40):28542-8.
1999
|