1 | STXBP5, STXBP5L
|
| Homozygous mutation of STXBP5L explains an autosomal recessive infantile-onset neurodegenerative disorder.
|
| Kumar R, Corbett MA, Smith NJ, Jolly LA, Tan C, Keating DJ, Duffield MD, Utsumi T, Moriya K, Smith KR, Hoischen A, Abbott K, Harbord MG, Compton AG, Woenig JA, Arts P, Kwint M, Wieskamp N, Gijsen S, Veltman JA, Bahlo M, Gleeson JG, Haan E, Gecz J.
|
| Hum Mol Genet 24(7):2000-10. doi: 10.1093/hmg/ddu614. Epub 2014 Dec 11. 2015
|
2 | STXBP5
|
| Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.
|
| Zhu Q, Yamakuchi M, Ture S, de la Luz Garcia-Hernandez M, Ko KA, Modjeski KL, LoMonaco MB, Johnson AD, O'Donnell CJ, Takai Y, Morrell CN, Lowenstein CJ.
|
| J Clin Invest 124(10):4503-16. doi: 10.1172/JCI71245. Epub 2014 Sep 17.
2014
|
3 | STX11, STXBP5
|
| Platelet secretion and hemostasis require syntaxin-binding protein STXBP5.
|
| Ye S, Huang Y, Joshi S, Zhang J, Yang F, Zhang G, Smyth SS, Li Z, Takai Y, Whiteheart SW.
|
| J Clin Invest 124(10):4517-28. doi: 10.1172/JCI75572. Epub 2014 Sep 17.
2014
|
4 | STXBP5
|
| Syntaxin-binding protein 5 exocytosis regulation: differential role in endothelial cells and platelets.
|
| Lillicrap D.
|
| J Clin Invest 124(10):4231-3. doi: 10.1172/JCI77511. Epub 2014 Sep 17.
2014
|
5 | STXBP5
|
| Neuron-specific expression of tomosyn1 in the mouse hippocampal dentate gyrus impairs spatial learning and memory.
|
| Barak B, Okun E, Ben-Simon Y, Lavi A, Shapira R, Madar R, Wang Y, Norman E, Sheinin A, Pita MA, Yizhar O, Mughal MR, Stuenkel E, van Praag H, Mattson MP, Ashery U.
|
| Neuromolecular Med 15(2):351-63. doi: 10.1007/s12017-013-8223-4. Epub 2013 Mar 22.
2013
|
6 | STXBP5
|
| Structural and functional analysis of tomosyn identifies domains important in exocytotic regulation.
|
| Williams AL, Bielopolski N, Meroz D, Lam AD, Passmore DR, Ben-Tal N, Ernst SA, Ashery U, Stuenkel EL.
|
| J Biol Chem 286(16):14542-53. doi: 10.1074/jbc.M110.215624. Epub 2011 Feb 17.
2011
|
7 | STXBP5, VAMP2
|
| The tail domain of tomosyn controls membrane fusion through tomosyn displacement by VAMP2.
|
| Yamamoto Y, Fujikura K, Sakaue M, Okimura K, Kobayashi Y, Nakamura T, Sakisaka T.
|
| Biochem Biophys Res Commun 399(1):24-30. Epub 2010 Jul 13.PMID: 20633536 S 2010
|
8 | STXBP5, SYT1
|
| Tomosyn inhibits synaptotagmin-1-mediated step of Ca2+-dependent neurotransmitter release through its N-terminal WD40 repeats.
|
| Yamamoto Y, Mochida S, Miyazaki N, Kawai K, Fujikura K, Kurooka T, Iwasaki K, Sakisaka T.
|
| J Biol Chem 285(52):40943-55. Epub 2010 Oct 26.
2010
|
9 | STXBP5
|
| Reciprocal intramolecular interactions of tomosyn control its inhibitory activity on SNARE complex formation.
|
| Yamamoto Y, Mochida S, Kurooka T, Sakisaka T.
|
| J Biol Chem 284(18):12480-90. Epub 2009 Mar 3.PMID: 19258327 2009
|
10 | STXBP5
|
| Novel copy number variants in children with autism and additional developmental anomalies.
|
| Davis LK, Meyer KJ, Rudd DS, Librant AL, Epping EA, Sheffield VC, Wassink TH.
|
| J Neurodev Disord 1(4):292-301. doi: 10.1007/s11689-009-9013-z. Epub 2009 May 27.
2009
|
11 | STXBP5
|
| Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release.
|
| Sakisaka T, Yamamoto Y, Mochida S, Nakamura M, Nishikawa K, Ishizaki H, Okamoto-Tanaka M, Miyoshi J, Fujiyoshi Y, Manabe T, Takai Y.
|
| J Cell Biol 183(2):323-37.PMID: 18936251 2008
|
12 | STXBP5
|
| Receptor-mediated regulation of tomosyn-syntaxin 1A interactions in bovine adrenal chromaffin cells.
|
| Gladycheva SE, Lam AD, Liu J, D'Andrea-Merrins M, Yizhar O, Lentz SI, Ashery U, Ernst SA, Stuenkel EL.
|
| J Biol Chem 282(31):22887-99. Epub 2007 Jun 1.PMID: 17545156 2007
|
13 | STXBP5
|
| Tomosyn-1 is involved in a post-docking event required for pancreatic beta-cell exocytosis.
|
| Cheviet S, Bezzi P, Ivarsson R, Renström E, Viertl D, Kasas S, Catsicas S, Regazzi R.
|
| J Cell Sci 119(Pt 14):2912-20. Epub 2006 Jun 20.PMID: 16787939 2006
|
14 | STXBP5
|
| Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
|
| Yizhar O, Matti U, Melamed R, Hagalili Y, Bruns D, Rettig J, Ashery U.
|
| Proc Natl Acad Sci U S A 101(8):2578-83. 2004
|
15 | STXBP5
|
| Three splicing variants of tomosyn and identification of their syntaxin-binding region.
|
| Yokoyama S, Shirataki H, Sakisaka T, Takai Y.
|
| Biochem Biophys Res Commun 256(1):218-22.PMID: 10066450 1999
|
16 | STXBP5
|
| Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process.
|
| Fujita Y, Shirataki H, Sakisaka T, Asakura T, Ohya T, Kotani H, Yokoyama S, Nishioka H, Matsuura Y, Mizoguchi A, Scheller RH, Takai Y.
|
| Neuron 20(5):905-15. 1998
|