| 1 | STMN2
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| Loss of mouse Stmn2 function causes motor neuropathy
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| Guerra San Juan I, Nash LA, Smith KS, Leyton-Jaimes MF, Qian M, Klim JR, Limone F, Dorr AB, Couto A, Pintacuda G, Joseph BJ, Whisenant DE, Noble C, Melnik V, Potter D, Holmes A, Burberry A, Verhage M, Eggan K.
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| Neuron. May 18;110(10):1671-1688.e6. doi: 10.1016/j.neuron.2022.02.011. Epub 2022 Mar 15. 2022
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| 2 | STMN2, TARDBP
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| Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy.
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| Krus KL, Strickland A, Yamada Y, Devault L, Schmidt RE, Bloom AJ, Milbrandt J, DiAntonio A.
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| Cell Rep. Jun 28;39(13):111001. doi: 10.1016/j.celrep.2022.111001. 2022
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| 3 | STMN2, TARDBP
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| Connecting TDP-43 Pathology with Neuropathy.
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| Klim JR, Pintacuda G, Nash LA, Guerra San Juan I, Eggan K.
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| Trends Neurosci. Jun;44(6):424-440. doi: 10.1016/j.tins.2021.02.008. Epub 2021 Apr 5. 2021
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| 4 | STMN2
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| Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype
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| Theunissen F, Anderton RS, Mastaglia FL, Flynn LL, Winter SJ, James I, Bedlack R, Hodgetts S, Fletcher S, Wilton SD, Laing NG, MacShane M, Needham M, Saunders A, Mackay-Sim A, Melamed Z, Ravits J, Cleveland DW, Akkari PA.
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| Front Aging Neurosci. Mar 26;13:658226. doi: 10.3389/fnagi.2021.658226. 2021
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| 5 | STMN2
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| Stathmin-2 Mediates Glucagon Secretion From Pancreatic α-Cells.
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| Asadi F, Dhanvantari S.
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| Front Endocrinol (Lausanne) Feb 4;11:29. doi: 10.3389/fendo.2020.00029. 2020
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| 6 | STMN2
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| ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair
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| Klim JR, Williams LA, Limone F, Guerra San Juan I, Davis-Dusenbery BN, Mordes DA, Burberry A, Steinbaugh MJ, Gamage KK, Kirchner R, Moccia R, Cassel SH, Chen K, Wainger BJ, Woolf CJ, Eggan K
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| Nat Neurosci. Feb;22(2):167-179. doi: 10.1038/s41593-018-0300-4. Epub 2019 Jan 14. 2019
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| 7 | STMN2, TARDBP
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| Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration
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| Melamed Z, López-Erauskin J, Baughn MW, Zhang O, Drenner K, Sun Y, Freyermuth F, McMahon MA, Beccari MS, Artates JW, Ohkubo T, Rodriguez M, Lin N, Wu D, Bennett CF, Rigo F, Da Cruz S, Ravits J, Lagier-Tourenne C, Cleveland DW.
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| Nat Neurosci. Feb;22(2):180-190. doi: 10.1038/s41593-018-0293-z. Epub 2019 Jan 14. 2019
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| 8 | STMN2, WDR47
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| WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy
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| Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bär S, Minocha S, Chevalier C, Po C; Sanger Mouse Genetics Project, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Hérault Y, Collins SC, Friant S, Godin JD, Yalcin B.
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| Proc Natl Acad Sci U S A Oct 31;114(44):E9308-E9317. doi: 10.1073/pnas.1713625114. Epub 2017 Oct 12. 2017
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| 9 | STMN2
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| Dynamic regulation of SCG10 in regenerating axons after injury.
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| Shin JE, Geisler S, DiAntonio A.
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| Exp Neurol. Feb;252:1-11. doi: 10.1016/j.expneurol.2013.11.007. Epub 2013 Nov 15. 2014
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| 10 | PAK4, STMN2
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| PAK4 kinase-mediated SCG10 phosphorylation involved in gastric cancer metastasis.
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| Guo Q, Su N, Zhang J, Li X, Miao Z, Wang G, Cheng M, Xu H, Cao L, Li F.
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| Oncogene ncogene. 2013 Jul 29. doi: 10.1038/onc.2013.296. [Epub ahead of print]
2013
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| 11 | STMN2
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| SCG10 is a JNK target in the axonal degeneration pathway.
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| Shin JE, Miller BR, Babetto E, Cho Y, Sasaki Y, Qayum S, Russler EV, Cavalli V, Milbrandt J, DiAntonio A.
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| Proc Natl Acad Sci U S A. 2012 . PMID: Dec 26;109(52):E3696-705. doi: 10.1073/pnas.1216204109. Epub 2012 Nov 27 2012
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| 12 | ELP1, HSAN3, STMN2
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| IKAP/Elp1 involvement in cytoskeleton regulation and implication for familial dysautonomia.
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| Cheishvili D, Maayan C, Cohen-Kupiec R, Lefler S, Weil M, Ast G, Razin A.
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| Hum Mol Genet 20(8):1585-94. Epub 2011 Jan 27. 2011
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| 13 | STMN2, STMN3
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| Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases.
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| Levy AD, Devignot V, Fukata Y, Fukata M, Sobel A, Chauvin S.
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| Mol Biol Cell. 22(11):1930-42. 2011
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| 14 | CIB1, STMN2
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| Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth.
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| Sobczak A, Debowska K, Blazejczyk M, Kreutz MR, Kuznicki J, Wojda U.
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| Biochim Biophys Acta 1813(5):1025-37. doi: 10.1016/j.bbamcr.2010.12.023. Epub 2011 Jan 6.
2011
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| 15 | GOSHS, KIFBP, STMN2
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| KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation.
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| Alves MM, Burzynski G, Delalande JM, Osinga J, van der Goot A, Dolga AM, de Graaff E, Brooks AS, Metzger M, Eisel UL, Shepherd I, Eggen BJ, Hofstra RM.
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| Hum Mol Genet 19(18):3642-51. Epub 2010 Jul 9.PMID: 20621975 2010
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| 16 | KIFBP, STMN2
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| Mutations in SCG10 are not involved in Hirschsprung disease.
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| Alves MM, Osinga J, Verheij JB, Metzger M, Eggen BJ, Hofstra RM.
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| PLoS One 5(12):e15144.PMID: 21187955 2010
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| 17 | RND1, STMN2
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| Rnd1 regulates axon extension by enhancing the microtubule destabilizing activity of SCG10.
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| Li YH, Ghavampur S, Bondallaz P, Will L, Grenningloh G, Püschel AW.
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| J Biol Chem 284(1):363-71. Epub 2008 Nov 7.
2009
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| 18 | BRSK1, BRSK2, CDC42, DCX, DOCK7, DPYSL2, GSK3A, GSK3B, IGF1, KIF13B, KIF2A, KLC1, LIS1, MAP1B, MAP2, MAPK8, MAPT, NIN, PAFAH1B1, SCG10, SCLIP, STK11, STMN1, STMN2, STMN3, STRADA
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| Microtubule assembly, organization and dynamics in axons and dendrites.
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| Conde C, Caceres A.
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| Nat Rev Neurosci. 10(5):319-32. 2009
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| 19 | STMN2
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| Stathmin-like 2, a developmentally-associated neuronal marker, is expressed and modulated during osteogenesis of human mesenchymal stem cells.
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| Chiellini C, Grenningloh G, Cochet O, Scheideler M, Trajanoski Z, Ailhaud G, Dani C, Amri EZ.
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| Biochem Biophys Res Commun 374(1):64-8. Epub 2008 Jul 9.
2008
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| 20 | CHGA, STMN2, STMN3
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| The trans-Golgi proteins SCLIP and SCG10 interact with chromogranin A to regulate neuroendocrine secretion.
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| Mahapatra NR, Taupenot L, Courel M, Mahata SK, O'Connor DT.
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| Biochemistry 47(27):7167-78. Epub 2008 Jun 13.
2008
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| 21 | STMN2
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| BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.
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| Gong Y, Wu J, Qiang H, Liu B, Chi Z, Chen T, Yin B, Peng X, Yuan J.
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| BMB Rep. 41(4):287-93. 2008
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| 22 | ADCY3,GAP43,KLF7,STMN2
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| Identification of genes regulated by transcription factor KLF7 in differentiating olfactory sensory neurons.
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| Kajimura D, Dragomir C, Ramirez F, Laub F.
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| Gene 388(1-2):34-42. Epub 2006 Oct 10. 2007
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| 23 | STMN2, STMN3
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| The "SCG10-LIke Protein" SCLIP is a novel regulator of axonal branching in hippocampal neurons, unlike SCG10.
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| Poulain FE, Sobel A.
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| Mol Cell Neurosci 34(2):137-46. Epub 2006 Dec 4.
2007
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| 24 | STMN2
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| Stathmin family protein SCG10 differentially regulates the plus and minus end dynamics of microtubules at steady state in vitro: implications for its role in neurite outgrowth.
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| Manna T, Grenningloh G, Miller HP, Wilson L.
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| Biochemistry 46(11):3543-52. Epub 2007 Feb 21.
2007
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| 25 | DYRK1A, GMNN, TFAP4, STMN2, REST
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| A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells.
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| Kim MY, Jeong BC, Lee JH, Kee HJ, Kook H, Kim NS, Kim YH, Kim JK, Ahn KY, Kim KK.
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| Proc Natl Acad Sci U S A 103(35):13074-9. Epub 2006 Aug 21. 2006
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| 26 | STMN1, STMN2, STMN3, STMN4
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| Expression of stathmin family genes in human tissues: non-neural-restricted expression for SCLIP.
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| Bieche I, Maucuer A, Laurendeau I, Lachkar S, Spano AJ, Frankfurter A, Levy P, Manceau V, Sobel A, Vidaud M, Curmi PA.
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| Genomics 81(4):400-10. 2003
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| 27 | STMN2, TRPC5
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| TRPC5 is a regulator of hippocampal neurite length and growth cone morphology.
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| Greka A, Navarro B, Oancea E, Duggan A, Clapham DE.
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| Nat Neurosci 6(8):837-45. 2003
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| 28 | STMN2
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| RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6.
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| Liu Z, Chatterjee TK, Fisher RA.
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| J Biol Chem. 277(40):37832-9. 2002
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| 29 | STMN2
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| Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study.
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| Bahn, S.; Mimmack, M.; Ryan, M.; Caldwell, M. A.; Jauniaux, E.; Starkey, M.; Svendsen, C. N.; Emson, P.
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| Lancet 359: 310-315 2002
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| 30 | STMN2
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| The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly.
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| Nixon AB, Grenningloh G, Casey PJ.
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| J Biol Chem. 277(20):18127-33. 2002
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| 31 | STMN1, STMN2, STMN2
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| Expression of stathmin and SCG10 proteins in the olfactory neurogenesis during development and after lesion in the adulthood.
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| Camoletto P, Colesanti A, Ozon S, Sobel A, Fasolo A.
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| Brain Res Bull 54(1):19-28. 2001
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| 32 | AIF1L, ANKHD1, ANKRD20A1, ANKRD27, ANKRD32, APH1B, APOLD1, ARMC4, ATXN10, C10orf10, C10orf10, C10orf118, C2orf14, C2orf16, C6orf60, C6orf62, C8orf71, CALCOCO1, CAMKK1, CCDC113, CCDC135, CCDC9, CCDC90B, CCNB2, CD99L2, CHPF, CLIC4, CLPB, CRELD1, CYBRD1, DDX47, DHRS7B, ESPN, FIP1L1, FLYWCH1, FYTTD1, GABARAPL1, GOLT1B, GPS2, GRIPAP1, HIGD1A, IER3IP1, KIF18A, KIRREL2, KLC2, LHX6, LMAN2L, MAF1, MED23, MIS12, MOB4, MYCBPAP, NCALD, NELF, NELFB, NRBF2, NRIP2, NRIP2, NRSN2, NUDT12, PCBD2, PMFBP1, PRPF31, PRSS23, QRSL1, RGMA, RGMB, RNF123, RNF146, RWDD3, SAMHD1, SECISBP2, SEMA4F, SERBP1, SERP1, SH3BP5L, SLC25A24, SLC25A39, SLC37A3, SLC41A2, SLC6A16, SMC6, SPEF1, STMN2, TARDBP, TBC1D3, TBL2, TFIP11, TIGD6, TIMMDC1, TMEM117, TMEM186, TNB, TRAF7, TRAPPC8, TSC22D3, TSPAN14, TWF2, UBA5, UNC50, WDR24, WDR37, WDR91, WSB1, YIPF3, ZC3H13, ZMYND12, ZMYND15, ZRANB3
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| Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
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| Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A.
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| Genome Res 11(3):422-35. 2001
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| 33 | STMN2
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| c-Jun N-terminal kinase-3 (JNK3)/stress-activated protein kinase-beta (SAPKbeta) binds and phosphorylates the neuronal microtubule regulator SCG10.
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| Neidhart S, Antonsson B, Gilliéron C, Vilbois F, Grenningloh G, Arkinstall S.
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| FEBS Lett. 508(2):259-64. 2001
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| 34 | ADIPOR1, AIG1, AMDHD2, ANKHD1, ANKRD20A1, ANKRD27, ANKRD32, APH1A, APH1B, APIP, APOLD1, ARS2, ASCC1, ATXN10, BOLA1, C10orf10, C14orf166, C19orf56, C20orf109, C20orf4, C2orf14, C2orf16, C6orf60, C6orf62, CALCOCO1, CAMKK1, CCDC113, CCDC53, CCDC9, CCNB2, CD99L2, CDK5RAP1, CDK5RAP1, CGI-96, CHMP5, CHPF, CIAO2B, CLIC4, CLPB, COPZ1, COQ4, COQ6, CRELD1, CUTC, CYBRD1, DDX47, DERA, DHRS7, DHRS7B, DHRS7B, DPH5, DTNB, DYNC1LI2, EEF1AKNMT, ELOVL1, EMC9, ERGIC3, ESPN, EXOSC1, EXOSC3, FAHD2A, FAM108B1, FAM18B, FAM32A, FAM82B, FCF1, FIP1L1, FLYWCH1, FYTTD1, GABARAPL1, GET4, GLOD4, GLRX2, GOLT1B, GOLT1B, GPR89A, GPS2, GRIPAP1, HDDC2, HDGFRP3, HIGD1A, IER3IP1, IFT52, ISOC1, KIF18A, KIF20B, KIRREL2, KL3, KLC2, LACTB2, LHX6, LMAN2L, LUC7L2, MAF1, MAGMAS, MECR, MED23, MED31, MEMO, METTL9, MIS12, MOABHD5, MOB4, MPC1, MRPL11, MRPL2, MRPL4, MRPL48, MRPS15, MRPS16, MRPS16P2, MRPS18C, MRPS23, MRPS33, MTCH1, MTERF3, MTO1, MYCBPAP, NCALD, NCIE2, NDUFAF1, NELF, NELFB, NFU1, NMD3, NOSIP, NRBF2, NRIP2, NRIP2, NRSN2, NUDT12, OTUD6B, PARVB, PCBD2, PHF20L1, PIGT, PMFBP1, PNAS-4, PRPF31, PRSS23, PTRH2, QRSL1, RBMX2, RGMA, RGMB, RNF103-CHMP3, RNF123, RNF146, RRNAD1, RRP15, RWDD1, RWDD3, SAMHD1, SAMM50, SCCPDH, SECISBP2, SEMA4F, SERBP1, SERBP1, SERP1, SH3BP5L, SIDT2, SLC25A24, SLC25A39, SLC35C2, SLC37A3, SLC41A2, SLC6A16, SLMO2, SMC6, SPEF1, SQRDL, STARD10, STMN2, SYF2, TARDBP, TBC1D3, TBL2, TFB1M, TFIP11, THAP4, THAP4, TIGD6, TIMMDC1, TMED5, TMED7, TMEM47, TPPP3, TRAF7, TRAPPC12, TRAPPC4, TRMT6, TRNT1, TSC22D3, TSPAN14, TWF2, UBE1DC1, UBE2J1, UCHL5, UNC50, USP39, UTP11L, VPS36, WDR37, WDR50, WDR91, WSB1, YARS2, YIPF3, YPEL5, ZC2HC1A, ZC3H13, ZDHHC9, ZMYND12, ZMYND15, ZRANB3
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| Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.
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| Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W.
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| Genome Res 10(5):703-13. 2000
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| 35 | STMN1, STMN2, STMN3, STMN4
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| The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network.
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| Gavet O, Ozon S, Manceau V, Lawler S, Curmi P, Sobel A.
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| J Cell Sci 111 ( Pt 22):3333-46. 1998
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| 36 | STMN2
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| Purification, characterization, and in vitro phosphorylation of the neuron-specific membrane-associated protein SCG10.
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| Antonsson B, Lütjens R, Di Paolo G, Kassel D, Allet B, Bernard A, Catsicas S, Grenningloh G.
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| Protein Expr Purif. 9(3):363-71. 1997
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| 37 | STMN2
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| SCG10, a neuron-specific growth-associated protein in Alzheimer's disease.
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| Okazaki T, Wang H, Masliah E, Cao M, Johnson SA, Sundsmo M, Saitoh T, Mori N.
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| Neurobiol Aging 16(6):883-94. 1995
|