| 1 | SAV1, STK25
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| STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism.
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| Bae SJ, Ni L, Luo X.
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| Elife Apr 15;9:e54863. doi: 10.7554/eLife.54863. 2020
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| 2 | STK25
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| Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.
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| Nuñez-Durán E, Aghajan M, Amrutkar M, Sütt S, Cansby E, Booten SL, Watt A, Ståhlman M, Stefan N, Häring HU, Staiger H, Borén J, Marschall HU, Mahlapuu M.
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| Hepatol Commun 2(1):69-83. doi: 10.1002/hep4.1128. eCollection 2018 Jan.
2017
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| 3 | STK25
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| Protein kinase STK25 aggravates the severity of non-alcoholic fatty pancreas disease in mice.
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| Nuñez-Durán E, Chanclón B, Sütt S, Real J, Marschall HU, Wernstedt Asterholm I, Cansby E, Mahlapuu M.
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| J Endocrinol 234(1):15-27. doi: 10.1530/JOE-17-0018. Epub 2017 Apr 25. 2017
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| 4 | STK25
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| Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle.
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| Chursa U, Nuñez-Durán E, Cansby E, Amrutkar M, Sütt S, Ståhlman M, Olsson BM, Borén J, Johansson ME, Bäckhed F, Johansson BR, Sihlbom C, Mahlapuu M.
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| Diabetologia 60(3):553-567. doi: 10.1007/s00125-016-4171-5. Epub 2016 Dec 16.
2017
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| 5 | STK25
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| STK25 is a critical determinant in nonalcoholic steatohepatitis.
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| Amrutkar M, Chursa U, Kern M, Nuñez-Durán E, Ståhlman M, Sütt S, Borén J, Johansson BR, Marschall HU, Blüher M, Mahlapuu M.
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| FASEB J 30(10):3628-3643. Epub 2016 Jul 15.
2016
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| 6 | STK25
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| Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans.
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| Amrutkar M, Kern M, Nuñez-Durán E, Ståhlman M, Cansby E, Chursa U, Stenfeldt E, Borén J, Blüher M, Mahlapuu M.
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| Diabetologia 59(2):341-53. doi: 10.1007/s00125-015-3801-7. Epub 2015 Nov 9.
2016
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| 7 | DEL2Q37, STK25
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| A novel 2q37 microdeletion containing human neural progenitors genes including STK25 results in severe developmental delay, epilepsy, and microcephaly.
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| Imitola J, Khurana DS, Teplyuk NM, Zucker M, Jethva R, Legido A, Krichevsky AM, Frangieh M, Walsh CA, Carvalho KS.
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| Am J Med Genet A 167A(11):2808-16. doi: 10.1002/ajmg.a.37268. Epub 2015 Aug 4.
2015
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| 8 | STK25
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| Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH.
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| Amrutkar M, Cansby E, Nuñez-Durán E, Pirazzi C, Ståhlman M, Stenfeldt E, Smith U, Borén J, Mahlapuu M.
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| FASEB J 29(4):1564-76. doi: 10.1096/fj.14-264937. Epub 2015 Jan 21.
2015
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| 9 | PDCD10, STK25, STK26
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| Differential expression of MST4, STK25 and PDCD10 between benign prostatic hyperplasia and prostate cancer.
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| Zhang H, Ma X, Peng S, Nan X, Zhao H.
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| Int J Clin Exp Pathol 7(11):8105-11. eCollection 2014.
2014
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| 10 | PDCD10, STK24, STK25, STK26
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| Structural mechanism of CCM3 heterodimerization with GCKIII kinases.
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| Zhang M, Dong L, Shi Z, Jiao S, Zhang Z, Zhang W, Liu G, Chen C, Feng M, Hao Q, Wang W, Yin M, Zhao Y, Zhang L, Zhou Z.
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| Structure 21(4):680-8. 2013
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| 11 | STK25
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| Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet.
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| Cansby E, Amrutkar M, Mannerås Holm L, Nerstedt A, Reyahi A, Stenfeldt E, Borén J, Carlsson P, Smith U, Zierath JR, Mahlapuu M.
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| FASEB J 27(9):3660-71. doi: 10.1096/fj.13-228494. Epub 2013 May 31.
2013
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| 12 | PDCD10, STK25
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| PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress.
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| Zhang H, Ma X, Deng X, Chen Y, Mo X, Zhang Y, Zhao H, Ma D.
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| Front Biosci (Landmark Ed) 17:2295-305.
2012
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| 13 | CCM2, STK25
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| STK25 protein mediates TrkA and CCM2 protein-dependent death in pediatric tumor cells of neural origin.
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| Costa B, Kean MJ, Ast V, Knight JD, Mett A, Levy Z, Ceccarelli DF, Badillo BG, Eils R, König R, Gingras AC, Fainzilber M.
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| J Biol Chem 287(35):29285-9. doi: 10.1074/jbc.C112.345397. Epub 2012 Jul 10.
2012
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| 14 | DAB1, STK25
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| Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice.
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| Matsuki T, Zaka M, Guerreiro R, van der Brug MP, Cooper JA, Cookson MR, Hardy JA, Howell BW.
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| PLoS One 7(2):e31152. doi: 10.1371/journal.pone.0031152. Epub 2012 Feb 15.
2012
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| 15 | RELN, STK25
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| Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment.
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| Matsuki T, Matthews RT, Cooper JA, van der Brug MP, Cookson MR, Hardy JA, Olson EC, Howell BW.
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| Cell 143(5):826-36. doi: 10.1016/j.cell.2010.10.029.
2010
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| 16 | STK25
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| SOK1 translocates from the Golgi to the nucleus upon chemical anoxia and induces apoptotic cell death.
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| Nogueira E, Fidalgo M, Molnar A, Kyriakis J, Force T, Zalvide J, Pombo CM.
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| J Biol Chem 283(23):16248-58. Epub 2008 Mar 25. 2008
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| 17 | ACOT2, AFAP1L1, ALG11, ANKS1A, ARMC6, ARPC1A, ARPC3, ARPC5L, ATG10, ATP5L, BAZ1A, BCAS2, C2orf44, CAPZA1, CAPZA2, CCDC47, CERS2, CMBL, CPSF2, CSTF3, CXorf56, EXT2, FAF2, FBXO4, FIBP, GLRX3, GPS1, GSKIP, INPP5K, KPNA4, KRT31, KRT32, KRT33A, KRT33B, KRT34, KRT36, LUC7L2, MAGED1, MED7, MMS22L, MPRIP, MPRIP, MRCL3, NAA25, NDN, NPEPPS, NRDE2, OLA1, ORCTL3, OSTF1, PH4B, PIP5K1B, PKIG, PMVK, PSMC1, PSMC2, PSPH, RAB11FIP1, RBX1, RNF219, RO60, RPS14, SF3B14, SF3B2, SFRS12, STK25, TLK2, TONSL, TPM3, TRMT112, TSPAN17, TWF2, UBE2M, UNC45A, UQCRC1, WRAP73, XPO7, ZRANB2
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| Large-scale mapping of human protein-protein interactions by mass spectrometry.
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| Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D.
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| Mol Syst Biol 3:89. Epub 2007 Mar 13. 2007
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| 18 | GOLGA2, YWHAZ, STK25
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| YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta.
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| Preisinger C, Short B, De Corte V, Bruyneel E, Haas A, Kopajtich R, Gettemans J, Barr FA.
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| J Cell Biol 164(7):1009-20. Epub 2004 Mar 22. 2004
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| 19 | STK25
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| Stk25 is a candidate gene for pseudopseudohypoparathyroidism.
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| Davids MS, Crawford E, Weremowicz S, Morton CC, Copeland NG, Gilbert DJ, Jenkins NA, Phelan MC, Comb MJ, Melnick MB.
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| Genomics 77(1/2):2-4. 2001
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| 20 | STK25
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| YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways.
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| Osada S, Izawa M, Saito R, Mizuno K, Suzuki A, Hirai S, Ohno S.
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| Oncogene 14(17):2047-57 1997
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| 21 | STK25
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| Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway.
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| Pombo CM, Bonventre JV, Molnar A, Kyriakis J, Force T.
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| EMBO J 15(17):4537-46 1996
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