Citations for
1NEUROD2, STIM1
NEUROD2 Regulates Stim1 Expression and Store-Operated Calcium Entry in Cortical Neurons.
Guner G, Guzelsoy G, Isleyen FS, Sahin GS, Akkaya C, Bayam E, Kotan EI, Kabakcioglu A, Ince-Dunn G.
eNeuro 4(1). pii: ENEURO.0255-16.2017. doi: 10.1523/ENEURO.0255-16.2017. eCollection 2017 Jan-Feb. 2017
2STIM1, STIM2
Deficient for endoplasmic reticulum calcium sensors Stim1 and Stim2 affects aberrant antibody affinity maturation in B cells.
Mao X, Zhang J, Han Y, Luan C, Hu Y, Hao Z, Chen M.
Oncotarget ncotarget. 2016 Aug 27. doi: 10.18632/oncotarget.11659. [Epub ahead of print] 2016
3STIM1, STIM2
Deficient for endoplasmic reticulum calcium sensors Stim1 and Stim2 affects aberrant antibody affinity maturation in B cells.
Mao X, Zhang J, Han Y, Luan C, Hu Y, Hao Z, Chen M.
Oncotarget ncotarget. 2016 Aug 27. doi: 10.18632/oncotarget.11659. [Epub ahead of print] 2016
4STIM1, STIM2
STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions.
Ong HL, de Souza LB, Zheng C, Cheng KT, Liu X, Goldsmith CM, Feske S, Ambudkar IS.
Sci Signal 8(359):ra3. doi: 10.1126/scisignal.2005748. Erratum in: Sci Signal. 2015 Feb 3;8(362):er2. 2015
5ORAI1, STIM1, STIM2
STIM1, STIM2, and Orai1 regulate store-operated calcium entry and purinergic activation of microglia.
Michaelis M, Nieswandt B, Stegner D, Eilers J, Kraft R.
Glia 63(4):652-63. doi: 10.1002/glia.22775. 2015
6STIM1
STIM1L traps and gates Orai1 channels without remodeling the cortical ER.
Saüc S, Bulla M, Nunes P, Orci L, Marchetti A, Antigny F, Bernheim L, Cosson P, Frieden M, Demaurex N.
J Cell Sci 128(8):1568-79. doi: 10.1242/jcs.164228. Epub 2015 Mar 3. 2015
7STIM1, STIM2
CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2.
Shaw PJ, Weidinger C, Vaeth M, Luethy K, Kaech SM, Feske S.
J Clin Invest 124(10):4549-63. doi: 10.1172/JCI76602. 2014
8ORAI1, STIM1, STIM2
Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site.
Wang X, Wang Y, Zhou Y, Hendron E, Mancarella S, Andrake MD, Rothberg BS, Soboloff J, Gill DL.
Nat Commun 5:3183. doi: 10.1038/ncomms4183. 2014
9GRM1, STIM1
STIM1 controls neuronal Ca²⁺ signaling, mGluR1-dependent synaptic transmission, and cerebellar motor behavior.
Hartmann J, Karl RM, Alexander RP, Adelsberger H, Brill MS, Rühlmann C, Ansel A, Sakimura K, Baba Y, Kurosaki T, Misgeld T, Konnerth A.
Neuron 82(3):635-44. doi: 10.1016/j.neuron.2014.03.027. 2014
10STIM1, TBAM
Constitutive Activation of the Calcium Sensor STIM1 Causes Tubular-Aggregate Myopathy.
Böhm J, Chevessier F, De Paula AM, Koch C, Attarian S, Feger C, Hantaï D, Laforêt P, Ghorab K, Vallat JM, Fardeau M, Figarella-Branger D, Pouget J, Romero NB, Koch M, Ebel C, Levy N, Krahn M, Eymard B, Bartoli M, Laporte J.
Am J Hum Genet 92(2):271-8. doi: 10.1016/j.ajhg.2012.12.007. Epub 2013 Jan 17. 2013
11ORAI1, STIM1
Regulation of CRAC channels by protein interactions and post-translational modification.
Srikanth S, Ribalet B, Gwack Y.
Channels (Austin) 7(3). [Epub ahead of print] 2013
12ORAI1, STIM1
Differential roles of the C- and N-termini of Orai1 in interacting with stromal interaction molecule 1 (STIM1) for Ca2+ release-activated Ca2+ (CRAC) channel activation.
Zheng H, Zhou MH, Hu C, Kuo E, Peng X, Hu J, Kuo L, Zhang SL.
J Biol Chem Biol Chem. 2013 Feb 27. [Epub ahead of print] 2013
13STIM1
STIM1-Regulated Ca(2+) Influx across the Apical and the Basolateral Membrane in Colonic Epithelium.
Onodera K, Pouokam E, Diener M.
J Membr Biol Membr Biol. 2013 Feb 9. [Epub ahead of print] 2013
14STIM1
The polybasic lysine-rich domain of plasma membrane-resident STIM1 is essential for the modulation of store-operated divalent cation entry by extracellular calcium.
Jardin I, Dionisio N, Frischauf I, Berna-Erro A, Woodard GE, Salido GM, Rosado JA.
Cell Signal ell Signal. 2013 Feb 8. doi:pii: S0898-6568(13)00036-3. 10.1016/j.cellsig.2013.01.025. [Epub ahead of print] 2013
15STIM1
Endoplasmic reticulum Ca2+ sensor STIM1 regulates actomyosin contractility of migratory cells.
Chen YT, Chen YF, Chiu WT, Wang YK, Chang HC, Shen MR.
J Cell Sci Cell Sci. 2013 Feb 1. [Epub ahead of print] 2013
16ORAI1, STIM1
The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function.
Jha A, Ahuja M, Maléth J, Moreno CM, Yuan JP, Kim MS, Muallem S.
J Cell Biol 202(1):71-9. doi: 10.1083/jcb.201301148. Epub 2013 Jul 1. 2013
17NFATC3, STIM1
Positive feedback control between STIM1 and NFATc3 is required for C2C12 myoblast differentiation.
Phuong TT, Yun YH, Kim SJ, Kang TM.
Biochem Biophys Res Commun 430(2):722-8. doi: 10.1016/j.bbrc.2012.11.082. Epub 2012 Dec 1. 2013
18SARAF, STIM1
The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function.
Jha A, Ahuja M, Maléth J, Moreno CM, Yuan JP, Kim MS, Muallem S.
J Cell Biol 202(1):71-9. doi: 10.1083/jcb.201301148. Epub 2013 Jul 1. 2013
19STIM1, STIM2
Oligomerization and Ca2+/calmodulin control binding of the ER Ca2+-sensors STIM1 and STIM2 to plasma membrane lipids.
Bhardwaj R, Müller HM, Nickel W, Seedorf M.
Biosci Rep 33(5). pii: e00077. doi: 10.1042/BSR20130089. 2013
20STIM1, STIM2
Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry.
Oh-Hora M, Komatsu N, Pishyareh M, Feske S, Hori S, Taniguchi M, Rao A, Takayanagi H.
Immunity 38(5):881-95. doi: 10.1016/j.immuni.2013.02.008. 2013
21ORAI1, STIM1
STIM1 regulates platelet-derived growth factor-induced migration and Ca2+ influx in human airway smooth muscle cells.
Suganuma N, Ito S, Aso H, Kondo M, Sato M, Sokabe M, Hasegawa Y.
PLoS One 7(9):e45056. doi: 10.1371/journal.pone.0045056. Epub 2012 Sep 11. 2012
22STIM1
Stromal interaction molecule 1 (STIM1) is involved in the regulation of mitochondrial shape and bioenergetics and plays a role in oxidative stress.
Henke N, Albrecht P, Pfeiffer A, Toutzaris D, Zanger K, Methner A.
J Biol Chem 287(50):42042-52. doi: 10.1074/jbc.M112.417212. Epub 2012 Oct 17. 2012
23STIM1
STIM1 is necessary for store-operated calcium entry in turning growth cones.
Mitchell CB, Gasperini RJ, Small DH, Foa L.
J Neurochem 122(6):1155-66. doi: 10.1111/j.1471-4159.2012.07840.x. Epub 2012 Jul 11. 2012
24ASPH, ORAI1, STIM1
Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1).
Srikanth S, Jew M, Kim KD, Yee MK, Abramson J, Gwack Y.
Proc Natl Acad Sci U S A 109(22):8682-7. doi: 10.1073/pnas.1200667109. Epub 2012 May 14. 2012
25STIM1
STIM1 is required for Ca2+ signaling during mammalian fertilization.
Lee K, Wang C, Machaty Z.
Dev Biol 367(2):154-62. doi: 10.1016/j.ydbio.2012.04.028. Epub 2012 May 4. 2012
26ORAI1, STIM1
Gated regulation of CRAC channel ion selectivity by STIM1.
McNally BA, Somasundaram A, Yamashita M, Prakriya M.
Nature 482(7384):241-5. doi: 10.1038/nature10752. 2012
27STIM1
Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1).
Yang X, Jin H, Cai X, Li S, Shen Y.
Proc Natl Acad Sci U S A 109(15):5657-62. doi: 10.1073/pnas.1118947109. Epub 2012 Mar 26. 2012
28STIM1, STIM2
STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjogren's syndrome.
Cheng KT, Alevizos I, Liu X, Swaim WD, Yin H, Feske S, Oh-hora M, Ambudkar IS.
Proc Natl Acad Sci U S A 109(36):14544-9. doi: 10.1073/pnas.1207354109. Erratum in: Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18625. 2012
29STIM1, SURF4
Surf4 modulates STIM1-dependent calcium entry.
Fujii Y, Shiota M, Ohkawa Y, Baba A, Wanibuchi H, Kinashi T, Kurosaki T, Baba Y.
Biochem Biophys Res Commun 422(4):615-20. doi: 10.1016/j.bbrc.2012.05.037. Epub 2012 May 15. 2012
30IMD10, STIM1
Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency.
Fuchs S, Rensing-Ehl A, Speckmann C, Bengsch B, Schmitt-Graeff A, Bondzio I, Maul-Pavicic A, Bass T, Vraetz T, Strahm B, Ankermann T, Benson M, Caliebe A, Fölster-Holst R, Kaiser P, Thimme R, Schamel WW, Schwarz K, Feske S, Ehl S.
J Immunol 188(3):1523-33. doi: 10.4049/jimmunol.1102507. Epub 2011 Dec 21. 2012
31SLN, STIM1
Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.
Seth M, Li T, Graham V, Burch J, Finch E, Stiber JA, Rosenberg PB.
Dev Dyn 241(4):639-47. doi: 10.1002/dvdy.23760. 2012
32STIM1
Different binding property of STIM1 and its novel splice variant STIM1L to Orai1, TRPC3, and TRPC6 channels.
Horinouchi T, Higashi T, Higa T, Terada K, Mai Y, Aoyagi H, Hatate C, Nepal P, Horiguchi M, Harada T, Miwa S.
Biochem Biophys Res Commun 428(2):252-8. doi: 10.1016/j.bbrc.2012.10.034. Epub 2012 Oct 12. 2012
33STIM1, STIM2
Identification of functional domains and novel binding partners of STIM proteins.
Saitoh N, Oritani K, Saito K, Yokota T, Ichii M, Sudo T, Fujita N, Nakajima K, Okada M, Kanakura Y.
J Cell Biochem 112(1):147-56. 2011
34STIM1
Role of the STIM1 C-terminal domain in STIM1 clustering.
Yu F, Sun L, Courjaret R, Machaca K.
J Biol Chem 286(10):8375-84. Epub 2011 Jan 10. 2011
35MFN2, STIM1
Mitofusin 2 regulates STIM1 migration from the Ca2+ store to the plasma membrane in cells with depolarized mitochondria.
Singaravelu K, Nelson C, Bakowski D, de Brito OM, Ng SW, Di Capite J, Powell T, Scorrano L, Parekh AB.
J Biol Chem 286(14):12189-201. Epub 2011 Jan 10. 2011
36ATP2A3, ORAI1, STIM1, STIM2
STIM1 and STIM2 are located in the acidic Ca2+ stores and associates with Orai1 upon depletion of the acidic stores in human platelets.
Zbidi H, Jardin I, Woodard GE, Lopez JJ, Berna-Erro A, Salido GM, Rosado JA.
J Biol Chem 286(14):12257-70. Epub 2011 Feb 14. 2011
37STIM1
STIM1L is a new actin-binding splice variant involved in fast repetitive Ca2+ release.
Darbellay B, Arnaudeau S, Bader CR, Konig S, Bernheim L.
J Cell Biol 194(2):335-46. 2011
38ATP2B1, SLC35G1, STIM1
POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters.
Krapivinsky G, Krapivinsky L, Stotz SC, Manasian Y, Clapham DE.
Proc Natl Acad Sci U S A 108(48):19234-9. doi: 10.1073/pnas.1117231108. Epub 2011 Nov 14. 2011
39PDIA3, STIM1
Modulation of STIM1 and capacitative Ca2+ entry by the endoplasmic reticulum luminal oxidoreductase ERp57.
Prins D, Groenendyk J, Touret N, Michalak M.
EMBO Rep 12(11):1182-8. doi: 10.1038/embor.2011.173. 2011
40ORAI1, STIM1
STIM1 gates the store-operated calcium channel ORAI1 in vitro.
Zhou Y, Meraner P, Kwon HT, Machnes D, Masatsugu OH, Zimmer J, Huang Y, Stura A, Rao A, Hogan PG.
Nat Struct Mol Biol 17(1):112-6. Epub 2009 Dec 27. 2010
41ORAI1, STIM1
SOAR and the polybasic STIM1 domains gate and regulate Orai channels.
Yuan JP, Zeng W, Dorwart MR, Choi YJ, Worley PF, Muallem S.
Nat Cell Biol 11(3):337-43. Epub 2009 Feb 1. 2009
42ORAI1, STIM1
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1.
Park CY, Hoover PJ, Mullins FM, Bachhawat P, Covington ED, Raunser S, Walz T, Garcia KC, Dolmetsch RE, Lewis RS.
Cell 136(5):876-90. Epub 2009 Feb 26. 2009
43ORAI1, STIM1
A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels.
Muik M, Fahrner M, Derler I, Schindl R, Bergsmann J, Frischauf I, Groschner K, Romanin C.
J Biol Chem 284(13):8421-6. Epub 2009 Feb 3. 2009
44ORAI1, ORAI2, ORAI3, STIM1, STIM2
STIM protein coupling in the activation of Orai channels.
Wang Y, Deng X, Zhou Y, Hendron E, Mancarella S, Ritchie MF, Tang XD, Baba Y, Kurosaki T, Mori Y, Soboloff J, Gill DL.
Proc Natl Acad Sci U S A 106(18):7391-6. Epub 2009 Apr 17. 2009
45ORAI1, ORAI2, ORAI3, STIM1, STIM2
STIM and Orai: Dynamic Intermembrane Coupling to Control Cellular Calcium Signals.
Deng X, Wang Y, Zhou Y, Soboloff J, Gill DL.
J Biol Chem 284(34):22501-5. Epub 2009 May 27. 2009
46ORAI1, STIM1, STIM2
The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels.
Zhou Y, Mancarella S, Wang Y, Yue C, Ritchie M, Gill DL, Soboloff J.
J Biol Chem 284(29):19164-8. Epub 2009 Jun 1. 2009
47ORAI1, STIM1
A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels.
Kawasaki T, Lange I, Feske S.
Biochem Biophys Res Commun 385(1):49-54. Epub 2009 May 9. Erratum in: Biochem Biophys Res Commun. 2009 Sep 25;387(3):623. 2009
48ORAI1, ORAI2, ORAI3, STIM1, STIM2
Biochemical and functional properties of the store-operated Ca2+ channels.
Salido GM, Sage SO, Rosado JA.
Cell Signal 21(4):457-61. Epub 2008 Nov 13. Review.PMID: 19049864 2009
49ORAI1, STIM1
Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant.
Frischauf I, Muik M, Derler I, Bergsmann J, Fahrner M, Schindl R, Groschner K, Romanin C.
J Biol Chem 284(32):21696-706. Epub 2009 Jun 8.PMID: 19506081 2009
50STIM1
Essential role of STIM1 in the development of cardiomyocyte hypertrophy.
Ohba T, Watanabe H, Murakami M, Sato T, Ono K, Ito H.
Biochem Biophys Res Commun 389(1):172-6. Epub 2009 Aug 26. 2009
51ORAI1, STIM1
STIM1 and calmodulin interact with Orai1 to induce Ca2+-dependent inactivation of CRAC channels.
Mullins FM, Park CY, Dolmetsch RE, Lewis RS.
Proc Natl Acad Sci U S A 106(36):15495-500. Epub 2009 Aug 21.PMID: 19706428 2009
52STIM1
Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis.
Smyth JT, Petranka JG, Boyles RR, DeHaven WI, Fukushima M, Johnson KL, Williams JG, Putney JW Jr.
Nat Cell Biol 11(12):1465-72. Epub 2009 Nov 1.PMID: 19881501 2009
53IMD10, STIM1
STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity.
Picard C, McCarl CA, Papolos A, Khalil S, Lüthy K, Hivroz C, LeDeist F, Rieux-Laucat F, Rechavi G, Rao A, Fischer A, Feske S.
N Engl J Med 360(19):1971-80. doi: 10.1056/NEJMoa0900082. 2009
54ORAI1, STIM1
Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation.
Lioudyno MI, Kozak JA, Penna A, Safrina O, Zhang SL, Sen D, Roos J, Stauderman KA, Cahalan MD.
Proc Natl Acad Sci U S A 105(6):2011-6. Epub 2008 Feb 4. 2008
55STIM1
Novel role for STIM1 as a trigger for calcium influx factor production.
Csutora P, Peter K, Kilic H, Park KM, Zarayskiy V, Gwozdz T, Bolotina VM.
J Biol Chem 283(21):14524-31. Epub 2008 Mar 12. 2008
56STIM1 , STIM2
Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2.
Zheng L, Stathopulos PB, Li GY, Ikura M.
Biochem Biophys Res Commun 369(1):240-6. Epub 2007 Dec 31. 2008
57STIM1
STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle.
Stiber J, Hawkins A, Zhang ZS, Wang S, Burch J, Graham V, Ward CC, Seth M, Finch E, Malouf N, Williams RS, Eu JP, Rosenberg P.
Nat Cell Biol 10(6):688-97. Epub 2008 May 18. 2008
58STIM1
Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses.
Baba Y, Nishida K, Fujii Y, Hirano T, Hikida M, Kurosaki T.
Nat Immunol 9(1):81-8. Epub 2007 Dec 2.PMID: 18059272 2008
59STIM1
Ca2+-store-dependent and -independent reversal of Stim1 localization and function.
Smyth JT, Dehaven WI, Bird GS, Putney JW Jr.
J Cell Sci 121(Pt 6):762-72. Epub 2008 Feb 19.PMID: 18285445 2008
60STIM1, ORAI1
Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation.
Li Z, Lu J, Xu P, Xie X, Chen L, Xu T.
J Biol Chem 282(40):29448-56. Epub 2007 Aug 16. 2007
61STIM1
Functional role of stromal interaction molecule 1 (STIM1) in vascular smooth muscle cells.
Takahashi Y, Watanabe H, Murakami M, Ono K, Munehisa Y, Koyama T, Nobori K, Iijima T, Ito H.
Biochem Biophys Res Commun 361(4):934-40. Epub 2007 Jul 26. 2007
62STIM1
Role of the microtubule cytoskeleton in the function of the store-operated Ca2+ channel activator STIM1.
Smyth JT, DeHaven WI, Bird GS, Putney JW Jr.
J Cell Sci 120(Pt 21):3762-71. Epub 2007 Oct 9.PMID: 17925382 2007
63STIM1, TRPC1
Interaction of STIM1 with endogenously expressed human canonical TRP1 upon depletion of intracellular Ca2+ stores.
Lopez JJ, Salido GM, Pariente JA, Rosado JA.
J Biol Chem 281(38):28254-64. Epub 2006 Jul 26. 2006
64STIM1
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane.
Zhang SL, Yu Y, Roos J, Kozak JA, Deerinck TJ, Ellisman MH, Stauderman KA, Cahalan MD.
Nature 437(7060):902-5. 2005
65STIM1
Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation.
Williams RT, Senior PV, Van Stekelenburg L, Layton JE, Smith PJ, Dziadek MA.
Biochim Biophys Acta 1596(1):131-7. 2002
66STIM1
STIM1: a novel phosphoprotein located at the cell surface.
Manji SS, Parker NJ, Williams RT, van Stekelenburg L, Pearson RB, Dziadek M, Smith PJ.
Biochim Biophys Acta 1481(1):147-55. 2000
67STIM1
Exon structure and promoter identification of STIM1 (alias GOK), a human gene causing growth arrest of the human tumor cell lines G401 and RD.
Sabbioni S, et al.
Cytogenet Cell Genet 86(3-4):214-218 1999
68BWS, TSSC2, STIM1, ST5
GOK: a gene at 11p15 involved in rhabdomyosarcoma and rhabdoid tumor development.
Sabbioni S, Barbanti-Brodano G, Croce CM, Negrini M.
Cancer Res 57(20):4493-7. 1997
69STIM1
Molecular cloning of a novel human gene (D11S4896E) at chromosomal region 11p15.5.
Parker NJ, et al.
Genomics 37 : 253-256. 1996