1 | ORF3, ORMDL3, STAT6, STING1
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| STING positively regulates human ORMDL3 expression through TBK1-IRF3-STAT6 complex mediation.
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| Cao Q, Juan CX, Zhang DQ, He J, Cao YZ, Pasha AB, Wang JY, Qi HX, Li S, Jin R, Zhou GP.
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| Exp Cell Res 370(2):498-505. doi: 10.1016/j.yexcr.2018.07.015. Epub 2018 Aug 1. 2018
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2 | CBLB, ORMDL3, STAT6
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| E3 ubiquitin ligase Cbl-b suppresses human ORMDL3 expression through STAT6 mediation.
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| Yang WX, Jin R, Jiang CM, Wang XH, Shu J, Li L, Zhu LH, Zhuang LL, Gao C, Zhou GP.
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| FEBS Lett 589(15):1975-80. doi: 10.1016/j.febslet.2015.06.015. Epub 2015 Jun 22.
2015
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3 | IL4, STAT6, iL19
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| Interleukin-4 up-regulation of epidermal interleukin-19 expression in keratinocytes involves the binding of signal transducer and activator of transcription 6 (Stat6) to the imperfect Stat6 sites.
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| Bao L, Alexander JB, Shi VY, Mohan GC, Chan LS.
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| Immunology 143(4):601-8. doi: 10.1111/imm.12339.
2014
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4 | IL4, STAT6
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| Reprogramming of lysosomal gene expression by interleukin-4 and Stat6.
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| Brignull LM, Czimmerer Z, Saidi H, Daniel B, Villela I, Bartlett NW, Johnston SL, Meira LB, Nagy L, Nohturfft A.
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| BMC Genomics 14:853. doi: 10.1186/1471-2164-14-853.
2013
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5 | NAB2, STAT6
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| Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing.
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| Robinson DR, Wu YM, Kalyana-Sundaram S, Cao X, Lonigro RJ, Sung YS, Chen CL, Zhang L, Wang R, Su F, Iyer MK, Roychowdhury S, Siddiqui J, Pienta KJ, Kunju LP, Talpaz M, Mosquera JM, Singer S, Schuetze SM, Antonescu CR, Chinnaiyan AM.
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| Nat Genet 45(2):180-5. doi: 10.1038/ng.2509. Epub 2013 Jan 13.
2013
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6 | IL13, IL4, STAT1, STAT6, TYK2
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| IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages.
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| Bhattacharjee A, Shukla M, Yakubenko VP, Mulya A, Kundu S, Cathcart MK.
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| Free Radic Biol Med ree Radic Biol Med. 2012 Nov 1. doi:pii: S0891-5849(12)01795-9. 10.1016/j.freeradbiomed.2012.10.553. [Epub ahead of print]
2012
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7 | STAT1, STAT6
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| An essential role for STAT6-STAT1 protein signaling in promoting macrophage cell-cell fusion.
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| Miyamoto H, Katsuyama E, Miyauchi Y, Hoshi H, Miyamoto K, Sato Y, Kobayashi T, Iwasaki R, Yoshida S, Mori T, Kanagawa H, Fujie A, Hao W, Morioka H, Matsumoto M, Toyama Y, Miyamoto T.
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| J Biol Chem 287(39):32479-84. Epub 2012 Aug 3.
2012
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8 | STAT6
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| STAT6-dependent regulation of Th9 development.
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| Goswami R, Jabeen R, Yagi R, Pham D, Zhu J, Goenka S, Kaplan MH.
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| J Immunol 188(3):968-75. doi: 10.4049/jimmunol.1102840. Epub 2011 Dec 16.
2012
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9 | LITAF, STAT6
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| Novel regulation of CCL2 gene expression by murine LITAF and STAT6B.
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| Tang X, Yang Y, Amar S.
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| PLoS One 6(9):e25083. Epub 2011 Sep 28. 2011
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10 | PKD, PKD1, STAT6, TPX2
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| Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease.
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| Olsan EE, Mukherjee S, Wulkersdorfer B, Shillingford JM, Giovannone AJ, Todorov G, Song X, Pei Y, Weimbs T.
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| Proc Natl Acad Sci U S A 108(44):18067-72. doi: 10.1073/pnas.1111966108. Epub 2011 Oct 24.
2011
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11 | STAT6
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| Activation of STAT6 by STING is critical for antiviral innate immunity.
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| Chen H, Sun H, You F, Sun W, Zhou X, Chen L, Yang J, Wang Y, Tang H, Guan Y, Xia W, Gu J, Ishikawa H, Gutman D, Barber G, Qin Z, Jiang Z.
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| Cell 147(2):436-46. doi: 10.1016/j.cell.2011.09.022.
2011
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12 | STAT6
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| STAT6 expression in glioblastoma promotes invasive growth.
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| Merk BC, Owens JL, Lopes MB, Silva CM, Hussaini IM.
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| BMC Cancer 11:184. doi: 10.1186/1471-2407-11-184.
2011
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13 | IL24, JUN, STAT6
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| Stat6 and c-Jun mediate Th2 cell-specific IL-24 gene expression.
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| Sahoo A, Lee CG, Jash A, Son JS, Kim G, Kwon HK, So JS, Im SH.
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| J Immunol 186(7):4098-109. doi: 10.4049/jimmunol.1002620. Epub 2011 Feb 25.
2011
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14 | IL4, STAT6
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| Differential requirements for IL-4/STAT6 signalling in CD4 T-cell fate determination and Th2-immune effector responses.
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| Forbes E, van Panhuys N, Min B, Le Gros G.
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| Immunol Cell Biol 88(3):240-3. Epub 2009 Dec 15. Review.PMID: 20010912 2010
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15 | STAT6
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| STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells.
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| Szanto A, Balint BL, Nagy ZS, Barta E, Dezso B, Pap A, Szeles L, Poliska S, Oros M, Evans RM, Barak Y, Schwabe J, Nagy L.
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| Immunity 33(5):699-712. doi: 10.1016/j.immuni.2010.11.009.
2010
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16 | STAT6
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| Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma.
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| Ritz O, Guiter C, Castellano F, Dorsch K, Melzner J, Jais JP, Dubois G, Gaulard P, Möller P, Leroy K.
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| Blood 114(6):1236-42. Epub 2009 May 7.
2009
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17 | ACP5, STAT6
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| Complex regulation of tartrate-resistant acid phosphatase (TRAP) expression by interleukin 4 (IL-4): IL-4 indirectly suppresses receptor activator of NF-kappaB ligand (RANKL)-mediated TRAP expression but modestly induces its expression directly.
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| Yu M, Moreno JL, Stains JP, Keegan AD.
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| J Biol Chem 284(47):32968-79. Epub 2009 Sep 28.PMID: 19801646 2009
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18 | PTPN1, STAT6
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| PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling.
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| Lu X, Malumbres R, Shields B, Jiang X, Sarosiek KA, Natkunam Y, Tiganis T, Lossos IS.
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| Blood 112(10):4098-108. Epub 2008 Aug 20.
2008
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19 | CCL17, STAT6
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| Identification of a distal tandem STAT6 element within the CCL17 locus.
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| Maier E, Wirnsberger G, Horejs-Hoeck J, Duschl A, Hebenstreit D.
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| Hum Immunol 68(12):986-92. Epub 2007 Nov 26.
2007
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20 | STAT6
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| Signal transducer and activator of transcription-6 (STAT6) is a constitutively expressed survival factor in human prostate cancer.
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| Das S, Roth CP, Wasson LM, Vishwanatha JK.
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| Prostate 67(14):1550-64.
2007
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21 | SPIC, STAT6
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| SPI-C and STAT6 can cooperate to stimulate IgE germline transcription.
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| Carlsson R, Thorell K, Liberg D, Leanderson T.
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| Biochem Biophys Res Commun 344(4):1155-60. Epub 2006 May 2.PMID: 16647686 2006
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22 | SND1, STAT6
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| The transcriptional co-activator protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB-binding protein and STAT6.
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| Välineva T, Yang J, Palovuori R, Silvennoinen O.
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| J Biol Chem 280(15):14989-96. Epub 2005 Feb 4.
2005
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23 | STAT6, GATA3, KIF3A, IL4, IL13, RAD50
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| Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3.
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| Lee DU, Rao A.
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| Proc Natl Acad Sci U S A 101(45):16010-5. Epub 2004 Oct 26. 2004
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24 | STAT6
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| STAT6 as an asthma candidate gene: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study.
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| Duetsch G, Illig T, Loesgen S, Rohde K, Klopp N, Herbon N, Gohlke H, Altmueller J, Wjst M.
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| Hum Mol Genet 11(6):613-21. 2002
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25 | STAT6, PRKAR1A
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| Specific gene expression in pancreatic beta-cells: cloning and characterization of differentially expressed genes.
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| Arava Y, et al.
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| Diabetes 48(3):552-6. 1999
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26 | STAT6
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| Localization of the human Stat6 gene to chromosome 12q13.3-q14.1, a region implicated in multiple solid tumors.
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| Patel BKR, et al.
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| Genomics 52 : 192-200. 1998
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27 | STAT6
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| Regulation of interleukin 4-mediated signaling by naturally occurring dominant negative and attenuated forms of human Stat6.
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| Patel BK, Pierce JH, LaRochelle WJ.
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| Proc Natl Acad Sci U S A 95(1):172-7. 1998
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28 | D12S1644, STAT6
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| Assignment of the STAT6 gene (STAT6) to human chromosome band 12q13 by in situ hybridization.
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| Leek JP, et al.
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| Cytogenet Cell Genet 79 : 208-209. 1997
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29 | NAB2, STAT6
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| The Nab2 and Stat6 genes share a common transcription termination region.
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| Svaren J, Apel ED, Simburger KS, Jenkins NA, Gilbert DJ, Copeland NA, Milbrandt J.
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| Genomics 41 : 33-39. 1997
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30 | IL4, IL13RA1, STAT6
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| Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex.
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| Miloux B, Laurent P, Bonnin O, Lupker J, Caput D, Vita N, Ferrara P.
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| FEBS Lett 401(2-3):163-6. 1997
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31 | IL13RA1, IL4, STAT6
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| An interleukin-4-induced transcription factor: IL-4 Stat.
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| Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, McKnight SL.
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| Science 265(5179):1701-6. 1994
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