1 | BRD9, STAT5B
|
| BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition.
|
| Del Gaudio N, Di Costanzo A, Liu NQ, Conte L, Migliaccio A, Vermeulen M, Martens JHA, Stunnenberg HG, Nebbioso A, Altucci L.
|
| Cell Death Dis. Apr 18;10(5):338. doi: 10.1038/s41419-019-1570-9 2019
|
2 | RGS4, STAT5B
|
| A novel regulatory role of RGS4 in STAT5B activation, neurite outgrowth and neuronal differentiation.
|
| Pallaki P, Georganta EM, Serafimidis I, Papakonstantinou MP, Papanikolaou V, Koutloglou S, Papadimitriou E, Agalou A, Tserga A, Simeonof A, Thomaidou D, Gaitanou M, Georgoussi Z.
|
| Neuropharmacology. May 1;117:408-421. doi: 10.1016/j.neuropharm.2017.02.012. Epub 2017 Feb 17. 2017
|
3 | GRAMD1A, STAT5B
|
| GRAM domain-containing protein 1A (GRAMD1A) promotes the expansion of hepatocellular carcinoma stem cell and hepatocellular carcinoma growth through STAT5.
|
| Fu B, Meng W, Zhao H, Zhang B, Tang H, Zou Y, Yao J, Li H, Zhang T.
|
| Sci Rep 6:31963. doi: 10.1038/srep31963.
2016
|
4 | GATA2, STAT5B
|
| The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance.
|
| Li Y, Qi X, Liu B, Huang H.
|
| J Immunol 194(9):4328-38. doi: 10.4049/jimmunol.1500018.
2015
|
5 | CDKN2A, CDKN2B, STAT5B
|
| Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.
|
| Grange M, Giordano M, Mas A, Roncagalli R, Firaguay G, Nunes JA, Ghysdael J, Schmitt-Verhulst AM, Auphan-Anezin N.
|
| Immunology 145(4):543-57. doi: 10.1111/imm.12471. Epub 2015 Jun 15.
2015
|
6 | DUSP4, STAT5B
|
| Dual-Specificity Phosphatase 4 Regulates STAT5 Protein Stability and Helper T Cell Polarization.
|
| Hsiao WY, Lin YC, Liao FH, Chan YC, Huang CY.
|
| PLoS One 10(12):e0145880. doi: 10.1371/journal.pone.0145880. eCollection 2015.
2015
|
7 | NFIB, STAT5B
|
| Coregulation of genetic programs by the transcription factors NFIB and STAT5.
|
| Robinson GW, Kang K, Yoo KH, Tang Y, Zhu BM, Yamaji D, Colditz V, Jang SJ, Gronostajski RM, Hennighausen L.
|
| Mol Endocrinol 28(5):758-67. doi: 10.1210/me.2012-1387. Epub 2014 Mar 28.
2014
|
8 | KCNH4, STAT5B
|
| A de novo 17q21.2 duplication in a boy with developmental delay and dysmorphic features.
|
| Poirsier-Violle C, Abourra A, Baumann C, Perrin L, Capri Y, Mignot C, Passemard S, Drunat S, Verloes A.
|
| Eur J Med Genet 56(4):226-8. doi: 10.1016/j.ejmg.2012.12.005. Epub 2013 Jan 19.
2013
|
9 | GHIS3, STAT5A, STAT5B
|
| Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.
|
| Jenks JA, Seki S, Kanai T, Huang J, Morgan AA, Scalco RC, Nath R, Bucayu R, Wit JM, Al-Herz W, Ramadan D, Jorge AA, Bacchetta R, Hwa V, Rosenfeld R, Nadeau KC.
|
| Clin Immunol 148(2):227-36. doi: 10.1016/j.clim.2013.04.014. Epub 2013 May 5.
2013
|
10 | SIRT1, STAT5A, STAT5B
|
| SIRT1 regulates adaptive response of the growth hormone--insulin-like growth factor-I axis under fasting conditions in liver.
|
| Yamamoto M, Iguchi G, Fukuoka H, Suda K, Bando H, Takahashi M, Nishizawa H, Seino S, Takahashi Y.
|
| Proc Natl Acad Sci U S A 110(37):14948-53. doi: 10.1073/pnas.1220606110. Epub 2013 Aug 26.
2013
|
11 | BCL6, STAT3, STAT5B
|
| STAT5 outcompetes STAT3 to regulate the expression of the oncogenic transcriptional modulator BCL6.
|
| Walker SR, Nelson EA, Yeh JE, Pinello L, Yuan GC, Frank DA.
|
| Mol Cell Biol 33(15):2879-90. doi: 10.1128/MCB.01620-12. Epub 2013 May 28.
2013
|
12 | PDZRN3, STAT5B
|
| Regulation of adipocyte differentiation of 3T3-L1 cells by PDZRN3.
|
| Honda T, Ishii A, Inui M.
|
| Am J Physiol Cell Physiol 304(11):C1091-7. doi: 10.1152/ajpcell.00343.2012. Epub 2013 Apr 10.
2013
|
13 | SENP1, STAT5B
|
| SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.
|
| Van Nguyen T, Angkasekwinai P, Dou H, Lin FM, Lu LS, Cheng J, Chin YE, Dong C, Yeh ET.
|
| Mol Cell 45(2):210-21. doi: 10.1016/j.molcel.2011.12.026.
2012
|
14 | STAT5A, STAT5B
|
| Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.
|
| Lin JX, Li P, Liu D, Jin HT, He J, Ata Ur Rasheed M, Rochman Y, Wang L, Cui K, Liu C, Kelsall BL, Ahmed R, Leonard WJ.
|
| Immunity 36(4):586-99. doi: 10.1016/j.immuni.2012.02.017.
2012
|
15 | DUSP4, IL2, STAT5B
|
| DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell development.
|
| Huang CY, Lin YC, Hsiao WY, Liao FH, Huang PY, Tan TH.
|
| Eur J Immunol 42(2):476-88. doi: 10.1002/eji.201041295. Epub 2011 Dec 27.
2012
|
16 | SKIL, STAT5B
|
| SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling.
|
| Jahchan NS, Wang D, Bissell MJ, Luo K.
|
| Development 139(17):3147-56. doi: 10.1242/dev.079616. Epub 2012 Jul 25.
2012
|
17 | PLCB3, PTPN6, STAT5B
|
| Short Stat5-interacting peptide derived from phospholipase C-β3 inhibits hematopoietic cell proliferation and myeloid differentiation.
|
| Yasudo H, Ando T, Xiao W, Kawakami Y, Kawakami T.
|
| PLoS One 6(9):e24995. doi: 10.1371/journal.pone.0024995. Epub 2011 Sep 20.
2011
|
18 | GHIS3, STAT5B
|
| A novel STAT5b mutation causing GH insensitivity syndrome associated withhyperprolactinemia and immune dysfunction in two male siblings.
|
| Pugliese-Pires P, Tonelli C, Dora JM, Silva P, Czepielewski MA, Simoni G, Arnhold IJ, Jorge A.
|
| Eur J Endocrinol ur J Endocrinol. 2010 Jun 10. [Epub ahead of print]PMID: 20538865 2010
|
19 | STAT5B
|
| Multi-component signaling complexes of the delta-opioid receptor with STAT5B and G proteins.
|
| Georganta EM, Agalou A, Georgoussi Z.
|
| Neuropharmacology europharmacology. 2010 Apr 28. [Epub ahead of print]PMID: 20433855 2010
|
20 | STAT5B
|
| Dispersed Chromosomal Stat5b-binding elements mediate growth hormone-activated insulin-like growth factor-I gene transcription.
|
| Chia DJ, Varco-Merth B, Rotwein P.
|
| J Biol Chem 285(23):17636-47. Epub 2010 Apr 7.PMID: 20378540 2010
|
21 | GAB2, STAT5B
|
| Gab2 promotes hematopoietic stem cell maintenance and self-renewal synergistically with STAT5.
|
| Li G, Wang Z, Miskimen KL, Zhang Y, Tse W, Bunting KD.
|
| PLoS One 5(2):e9152. doi: 10.1371/journal.pone.0009152.
2010
|
22 | LYN, PLCB3, PTPN6, STAT5B
|
| Lyn- and PLC-beta3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease.
|
| Xiao W, Ando T, Wang HY, Kawakami Y, Kawakami T.
|
| Blood 116(26):6003-13. doi: 10.1182/blood-2010-05-283937. Epub 2010 Sep 21.
2010
|
23 | MTF1, SLC30A2, STAT5B
|
| STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells.
|
| Guo L, Lichten LA, Ryu MS, Liuzzi JP, Wang F, Cousins RJ.
|
| Proc Natl Acad Sci U S A 107(7):2818-23. doi: 10.1073/pnas.0914941107. Epub 2010 Jan 27.
2010
|
24 | STAT5A, STAT5B
|
| The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.
|
| Kimura A, Rieger MA, Simone JM, Chen W, Wickre MC, Zhu BM, Hoppe PS, O'Shea JJ, Schroeder T, Hennighausen L.
|
| Blood 114(21):4721-8. Epub 2009 Sep 24.PMID: 19779039 2009
|
25 | RARA, STAT5B
|
| Acute promyelocytic leukemia harboring a STAT5B-RARA fusion gene and a G596V missense mutation in the STAT5B SH2 domain of the STAT5B-RARA.
|
| Iwanaga E, Nakamura M, Nanri T, Kawakita T, Horikawa K, Mitsuya H, Asou N.
|
| Eur J Haematol 83(5):499-501. Epub 2009 Jul 18. No abstract available. PMID: 19624718 2009
|
26 | SRC, STAT5B
|
| c-Src tyrosine kinase co-associates with and phosphorylates signal transducer and activator of transcription 5b which mediates the proliferation of normal human B lymphocytes.
|
| Cayer MP, Proulx M, Ma XZ, Sakac D, Giguère JF, Drouin M, Néron S, Branch DR, Jung D.
|
| Clin Exp Immunol 156(3):419-27.PMID: 19438593 2009
|
27 | BCL10, STAT5B
|
| STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells.
|
| Nagy ZS, LeBaron MJ, Ross JA, Mitra A, Rui H, Kirken RA.
|
| Mol Cancer 8:67.
2009
|
28 | STAT5A, STAT5B
|
| Transcription factor Stat5 synergizes with androgen receptor in prostate cancer cells.
|
| Tan SH, Dagvadorj A, Shen F, Gu L, Liao Z, Abdulghani J, Zhang Y, Gelmann EP, Zellweger T, Culig Z, Visakorpi T, Bubendorf L, Kirken RA, Karras J, Nevalainen MT.
|
| Cancer Res 68(1):236-48.PMID: 18172316 2008
|
29 | RARA, STAT5B
|
| Detection of the STAT5B-RARA fusion transcript in acute promyelocytic leukemia with the normal chromosome 17 on G-banding.
|
| Kusakabe M, Suzukawa K, Nanmoku T, Obara N, Okoshi Y, Mukai HY, Hasegawa Y, Kojima H, Kawakami Y, Ninomiya H, Nagasawa T.
|
| Eur J Haematol 80(5):444-7. Epub 2008 Jan 23.PMID: 18221386 2008
|
30 | RUNX1, RUNX2, RUNX3, STAT5B
|
| Physical and functional interactions between STAT5 and Runx transcription factors.
|
| Ogawa S, Satake M, Ikuta K.
|
| J Biochem 143(5):695-709. Epub 2008 Feb 22.PMID: 18296717 2008
|
31 | STAT5B, LIF
|
| STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.
|
| Rodriguez Granillo A, Boffi JC, Baranao L, Kordon E, Pecci A, Guberman A.
|
| Biochem Biophys Res Commun 356(3):727-32. Epub 2007 Mar 16. 2007
|
32 | GH1, GHIS3, IGF1, IGF1D, IGHD1, IGHD2, STAT5B
|
| Genetic disorders in the growth hormone - insulin-like growth factor-I axis.
|
| Walenkamp MJ, Wit JM.
|
| Horm Res 66(5):221-30. Review.
2006
|
33 | ACO1, STAT5A, STAT5B
|
| STAT5 proteins are involved in down-regulation of iron regulatory protein 1 gene expression by nitric oxide.
|
| Starzynski RR, Gonçalves AS, Muzeau F, Tyrolczyk Z, Smuda E, Drapier JC, Beaumont C, Lipinski P.
|
| Biochem J 400(2):367-75.
2006
|
34 | STAT5B
|
| STAT5 contributes to interferon resistance of melanoma cells.
|
| Wellbrock C, Weisser C, Hassel JC, Fischer P, Becker J, Vetter CS, Behrmann I, Kortylewski M, Heinrich PC, Schartl M.
|
| Curr Biol 15(18):1629-39. 2005
|
35 | GHIS3, STAT5B
|
| Growth hormone insensitivity associated with a STAT5b mutation.
|
| Kofoed EM, Hwa V, Little B, Woods KA, Buckway CK, Tsubaki J, Pratt KL, Bezrodnik L, Jasper H, Tepper A, Heinrich JJ, Rosenfeld RG.
|
| N Engl J Med 349(12):1139-47. No abstract available. 2003
|
36 | STAT5B
|
| Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b.
|
| Kabotyanski EB, Rosen JM.
|
| J Biol Chem 278(19):17218-27. Epub 2003 Mar 5. 2003
|
37 | RARA, STAT5B
|
| Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways.
|
| Dong S, Tweardy DJ.
|
| Blood 99(8):2637-46. 2002
|
38 | STAT5A, STAT5B
|
| The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoter.
|
| Ambrosio R, Fimiani G, Monfregola J, Sanzari E, De Felice N, Salerno MC, Pignata C, D'Urso M, Ursini MV.
|
| Gene 285(1-2):311-8. 2002
|
39 | NCOR2, STAT5B, STAT5A
|
| Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription.
|
| Nakajima H, Brindle PK, Handa M, Ihle JN.
|
| EMBO J 20(23):6836-44. 2001
|
40 | STAT5B
|
| A functional DNA binding domain is required for growth hormone-induced nuclear accumulation of Stat5B.
|
| Herrington J, et al.
|
| J Biol Chem 274(8):5138-45. 1999
|
41 | STAT5B, STAT5A
|
| STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation.
|
| Welte T, et al.
|
| Science 283(5399):222-5. 1999
|
42 | STAT5A, STAT5B
|
| STAT5 Signaling in Sexually Dimorphic Gene Expression and Growth Patterns.
|
| Davey HW, et al.
|
| Am J Hum Genet 65(4):959-965 1999
|
43 | STAT5B
|
| Activation of the signal transducers and activators of transcription signaling pathway by growth hormone (GH) in skin fibroblasts from normal and GH binding protein-positive Laron Syndrome children.
|
| Freeth JS, et al.
|
| Endocrinology 139(1):20-8 1998
|
44 | STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B
|
| STATs and gene regulation.
|
| Darnell JE Jr.
|
| Science 277(5332):1630-5. Review. 1997
|
45 | STAT5A, STAT5B
|
| Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.
|
| Lin JX, et al.
|
| J Biol Chem 271 : 10738-10744. 1996
|
46 | BRDD9, STAT5B
|
| BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition.
|
| Del Gaudio N, Di Costanzo A, Liu NQ, Conte L, Migliaccio A, Vermeulen M, Martens JHA, Stunnenberg HG, Nebbioso A, Altucci L.
|
|
|