Citations for
1BRD9, STAT5B
BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition.
Del Gaudio N, Di Costanzo A, Liu NQ, Conte L, Migliaccio A, Vermeulen M, Martens JHA, Stunnenberg HG, Nebbioso A, Altucci L.
Cell Death Dis. Apr 18;10(5):338. doi: 10.1038/s41419-019-1570-9 2019
2RGS4, STAT5B
A novel regulatory role of RGS4 in STAT5B activation, neurite outgrowth and neuronal differentiation.
Pallaki P, Georganta EM, Serafimidis I, Papakonstantinou MP, Papanikolaou V, Koutloglou S, Papadimitriou E, Agalou A, Tserga A, Simeonof A, Thomaidou D, Gaitanou M, Georgoussi Z.
Neuropharmacology. May 1;117:408-421. doi: 10.1016/j.neuropharm.2017.02.012. Epub 2017 Feb 17. 2017
3GRAMD1A, STAT5B
GRAM domain-containing protein 1A (GRAMD1A) promotes the expansion of hepatocellular carcinoma stem cell and hepatocellular carcinoma growth through STAT5.
Fu B, Meng W, Zhao H, Zhang B, Tang H, Zou Y, Yao J, Li H, Zhang T.
Sci Rep 6:31963. doi: 10.1038/srep31963. 2016
4GATA2, STAT5B
The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance.
Li Y, Qi X, Liu B, Huang H.
J Immunol 194(9):4328-38. doi: 10.4049/jimmunol.1500018. 2015
5CDKN2A, CDKN2B, STAT5B
Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.
Grange M, Giordano M, Mas A, Roncagalli R, Firaguay G, Nunes JA, Ghysdael J, Schmitt-Verhulst AM, Auphan-Anezin N.
Immunology 145(4):543-57. doi: 10.1111/imm.12471. Epub 2015 Jun 15. 2015
6DUSP4, STAT5B
Dual-Specificity Phosphatase 4 Regulates STAT5 Protein Stability and Helper T Cell Polarization.
Hsiao WY, Lin YC, Liao FH, Chan YC, Huang CY.
PLoS One 10(12):e0145880. doi: 10.1371/journal.pone.0145880. eCollection 2015. 2015
7NFIB, STAT5B
Coregulation of genetic programs by the transcription factors NFIB and STAT5.
Robinson GW, Kang K, Yoo KH, Tang Y, Zhu BM, Yamaji D, Colditz V, Jang SJ, Gronostajski RM, Hennighausen L.
Mol Endocrinol 28(5):758-67. doi: 10.1210/me.2012-1387. Epub 2014 Mar 28. 2014
8KCNH4, STAT5B
A de novo 17q21.2 duplication in a boy with developmental delay and dysmorphic features.
Poirsier-Violle C, Abourra A, Baumann C, Perrin L, Capri Y, Mignot C, Passemard S, Drunat S, Verloes A.
Eur J Med Genet 56(4):226-8. doi: 10.1016/j.ejmg.2012.12.005. Epub 2013 Jan 19. 2013
9GHIS3, STAT5A, STAT5B
Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.
Jenks JA, Seki S, Kanai T, Huang J, Morgan AA, Scalco RC, Nath R, Bucayu R, Wit JM, Al-Herz W, Ramadan D, Jorge AA, Bacchetta R, Hwa V, Rosenfeld R, Nadeau KC.
Clin Immunol 148(2):227-36. doi: 10.1016/j.clim.2013.04.014. Epub 2013 May 5. 2013
10SIRT1, STAT5A, STAT5B
SIRT1 regulates adaptive response of the growth hormone--insulin-like growth factor-I axis under fasting conditions in liver.
Yamamoto M, Iguchi G, Fukuoka H, Suda K, Bando H, Takahashi M, Nishizawa H, Seino S, Takahashi Y.
Proc Natl Acad Sci U S A 110(37):14948-53. doi: 10.1073/pnas.1220606110. Epub 2013 Aug 26. 2013
11BCL6, STAT3, STAT5B
STAT5 outcompetes STAT3 to regulate the expression of the oncogenic transcriptional modulator BCL6.
Walker SR, Nelson EA, Yeh JE, Pinello L, Yuan GC, Frank DA.
Mol Cell Biol 33(15):2879-90. doi: 10.1128/MCB.01620-12. Epub 2013 May 28. 2013
12PDZRN3, STAT5B
Regulation of adipocyte differentiation of 3T3-L1 cells by PDZRN3.
Honda T, Ishii A, Inui M.
Am J Physiol Cell Physiol 304(11):C1091-7. doi: 10.1152/ajpcell.00343.2012. Epub 2013 Apr 10. 2013
13SENP1, STAT5B
SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.
Van Nguyen T, Angkasekwinai P, Dou H, Lin FM, Lu LS, Cheng J, Chin YE, Dong C, Yeh ET.
Mol Cell 45(2):210-21. doi: 10.1016/j.molcel.2011.12.026. 2012
14STAT5A, STAT5B
Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.
Lin JX, Li P, Liu D, Jin HT, He J, Ata Ur Rasheed M, Rochman Y, Wang L, Cui K, Liu C, Kelsall BL, Ahmed R, Leonard WJ.
Immunity 36(4):586-99. doi: 10.1016/j.immuni.2012.02.017. 2012
15DUSP4, IL2, STAT5B
DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell development.
Huang CY, Lin YC, Hsiao WY, Liao FH, Huang PY, Tan TH.
Eur J Immunol 42(2):476-88. doi: 10.1002/eji.201041295. Epub 2011 Dec 27. 2012
16SKIL, STAT5B
SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling.
Jahchan NS, Wang D, Bissell MJ, Luo K.
Development 139(17):3147-56. doi: 10.1242/dev.079616. Epub 2012 Jul 25. 2012
17PLCB3, PTPN6, STAT5B
Short Stat5-interacting peptide derived from phospholipase C-β3 inhibits hematopoietic cell proliferation and myeloid differentiation.
Yasudo H, Ando T, Xiao W, Kawakami Y, Kawakami T.
PLoS One 6(9):e24995. doi: 10.1371/journal.pone.0024995. Epub 2011 Sep 20. 2011
18GHIS3, STAT5B
A novel STAT5b mutation causing GH insensitivity syndrome associated withhyperprolactinemia and immune dysfunction in two male siblings.
Pugliese-Pires P, Tonelli C, Dora JM, Silva P, Czepielewski MA, Simoni G, Arnhold IJ, Jorge A.
Eur J Endocrinol ur J Endocrinol. 2010 Jun 10. [Epub ahead of print]PMID: 20538865 2010
19STAT5B
Multi-component signaling complexes of the delta-opioid receptor with STAT5B and G proteins.
Georganta EM, Agalou A, Georgoussi Z.
Neuropharmacology europharmacology. 2010 Apr 28. [Epub ahead of print]PMID: 20433855 2010
20STAT5B
Dispersed Chromosomal Stat5b-binding elements mediate growth hormone-activated insulin-like growth factor-I gene transcription.
Chia DJ, Varco-Merth B, Rotwein P.
J Biol Chem 285(23):17636-47. Epub 2010 Apr 7.PMID: 20378540 2010
21GAB2, STAT5B
Gab2 promotes hematopoietic stem cell maintenance and self-renewal synergistically with STAT5.
Li G, Wang Z, Miskimen KL, Zhang Y, Tse W, Bunting KD.
PLoS One 5(2):e9152. doi: 10.1371/journal.pone.0009152. 2010
22LYN, PLCB3, PTPN6, STAT5B
Lyn- and PLC-beta3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease.
Xiao W, Ando T, Wang HY, Kawakami Y, Kawakami T.
Blood 116(26):6003-13. doi: 10.1182/blood-2010-05-283937. Epub 2010 Sep 21. 2010
23MTF1, SLC30A2, STAT5B
STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells.
Guo L, Lichten LA, Ryu MS, Liuzzi JP, Wang F, Cousins RJ.
Proc Natl Acad Sci U S A 107(7):2818-23. doi: 10.1073/pnas.0914941107. Epub 2010 Jan 27. 2010
24STAT5A, STAT5B
The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.
Kimura A, Rieger MA, Simone JM, Chen W, Wickre MC, Zhu BM, Hoppe PS, O'Shea JJ, Schroeder T, Hennighausen L.
Blood 114(21):4721-8. Epub 2009 Sep 24.PMID: 19779039 2009
25RARA, STAT5B
Acute promyelocytic leukemia harboring a STAT5B-RARA fusion gene and a G596V missense mutation in the STAT5B SH2 domain of the STAT5B-RARA.
Iwanaga E, Nakamura M, Nanri T, Kawakita T, Horikawa K, Mitsuya H, Asou N.
Eur J Haematol 83(5):499-501. Epub 2009 Jul 18. No abstract available. PMID: 19624718 2009
26SRC, STAT5B
c-Src tyrosine kinase co-associates with and phosphorylates signal transducer and activator of transcription 5b which mediates the proliferation of normal human B lymphocytes.
Cayer MP, Proulx M, Ma XZ, Sakac D, Giguère JF, Drouin M, Néron S, Branch DR, Jung D.
Clin Exp Immunol 156(3):419-27.PMID: 19438593 2009
27BCL10, STAT5B
STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells.
Nagy ZS, LeBaron MJ, Ross JA, Mitra A, Rui H, Kirken RA.
Mol Cancer 8:67. 2009
28STAT5A, STAT5B
Transcription factor Stat5 synergizes with androgen receptor in prostate cancer cells.
Tan SH, Dagvadorj A, Shen F, Gu L, Liao Z, Abdulghani J, Zhang Y, Gelmann EP, Zellweger T, Culig Z, Visakorpi T, Bubendorf L, Kirken RA, Karras J, Nevalainen MT.
Cancer Res 68(1):236-48.PMID: 18172316 2008
29RARA, STAT5B
Detection of the STAT5B-RARA fusion transcript in acute promyelocytic leukemia with the normal chromosome 17 on G-banding.
Kusakabe M, Suzukawa K, Nanmoku T, Obara N, Okoshi Y, Mukai HY, Hasegawa Y, Kojima H, Kawakami Y, Ninomiya H, Nagasawa T.
Eur J Haematol 80(5):444-7. Epub 2008 Jan 23.PMID: 18221386 2008
30RUNX1, RUNX2, RUNX3, STAT5B
Physical and functional interactions between STAT5 and Runx transcription factors.
Ogawa S, Satake M, Ikuta K.
J Biochem 143(5):695-709. Epub 2008 Feb 22.PMID: 18296717 2008
31STAT5B, LIF
STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.
Rodriguez Granillo A, Boffi JC, Baranao L, Kordon E, Pecci A, Guberman A.
Biochem Biophys Res Commun 356(3):727-32. Epub 2007 Mar 16. 2007
32GH1, GHIS3, IGF1, IGF1D, IGHD1, IGHD2, STAT5B
Genetic disorders in the growth hormone - insulin-like growth factor-I axis.
Walenkamp MJ, Wit JM.
Horm Res 66(5):221-30. Review. 2006
33ACO1, STAT5A, STAT5B
STAT5 proteins are involved in down-regulation of iron regulatory protein 1 gene expression by nitric oxide.
Starzynski RR, Gonçalves AS, Muzeau F, Tyrolczyk Z, Smuda E, Drapier JC, Beaumont C, Lipinski P.
Biochem J 400(2):367-75. 2006
34STAT5B
STAT5 contributes to interferon resistance of melanoma cells.
Wellbrock C, Weisser C, Hassel JC, Fischer P, Becker J, Vetter CS, Behrmann I, Kortylewski M, Heinrich PC, Schartl M.
Curr Biol 15(18):1629-39. 2005
35GHIS3, STAT5B
Growth hormone insensitivity associated with a STAT5b mutation.
Kofoed EM, Hwa V, Little B, Woods KA, Buckway CK, Tsubaki J, Pratt KL, Bezrodnik L, Jasper H, Tepper A, Heinrich JJ, Rosenfeld RG.
N Engl J Med 349(12):1139-47. No abstract available. 2003
36STAT5B
Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b.
Kabotyanski EB, Rosen JM.
J Biol Chem 278(19):17218-27. Epub 2003 Mar 5. 2003
37RARA, STAT5B
Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways.
Dong S, Tweardy DJ.
Blood 99(8):2637-46. 2002
38STAT5A, STAT5B
The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoter.
Ambrosio R, Fimiani G, Monfregola J, Sanzari E, De Felice N, Salerno MC, Pignata C, D'Urso M, Ursini MV.
Gene 285(1-2):311-8. 2002
39NCOR2, STAT5B, STAT5A
Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription.
Nakajima H, Brindle PK, Handa M, Ihle JN.
EMBO J 20(23):6836-44. 2001
40STAT5B
A functional DNA binding domain is required for growth hormone-induced nuclear accumulation of Stat5B.
Herrington J, et al.
J Biol Chem 274(8):5138-45. 1999
41STAT5B, STAT5A
STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation.
Welte T, et al.
Science 283(5399):222-5. 1999
42STAT5A, STAT5B
STAT5 Signaling in Sexually Dimorphic Gene Expression and Growth Patterns.
Davey HW, et al.
Am J Hum Genet 65(4):959-965 1999
43STAT5B
Activation of the signal transducers and activators of transcription signaling pathway by growth hormone (GH) in skin fibroblasts from normal and GH binding protein-positive Laron Syndrome children.
Freeth JS, et al.
Endocrinology 139(1):20-8 1998
44STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B
STATs and gene regulation.
Darnell JE Jr.
Science 277(5332):1630-5. Review. 1997
45STAT5A, STAT5B
Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.
Lin JX, et al.
J Biol Chem 271 : 10738-10744. 1996
46BRDD9, STAT5B
BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition.
Del Gaudio N, Di Costanzo A, Liu NQ, Conte L, Migliaccio A, Vermeulen M, Martens JHA, Stunnenberg HG, Nebbioso A, Altucci L.