Citations for
1LONP1, STAR
StAR enhances transcription of genes encoding the mitochondrial proteases involved in its own degradation.
Bahat A, Perlberg S, Melamed-Book N, Lauria I, Langer T, Orly J.
Mol Endocrinol 28(2):208-24. doi: 10.1210/me.2013-1275. Epub 2013 Jan 1. 2014
2CYP11B2, GPLD1, STAR
Phospholipase D activity underlies very-low-density lipoprotein (VLDL)-induced aldosterone production in adrenal glomerulosa cells.
Tsai YY, Rainey WE, Pan ZQ, Frohman MA, Choudhary V, Bollag WB.
Endocrinology 155(9):3550-60. doi: 10.1210/en.2014-1159. Epub 2014 Jun 23. 2014
3STAR, STARD5, STARD6
STARD5 specific ligand binding: comparison with STARD1 and STARD4 subfamilies.
Létourneau D, Lefebvre A, Lavigne P, LeHoux JG.
Mol Cell Endocrinol 371(1-2):20-5. doi: 10.1016/j.mce.2013.01.004. Review. 2013
4AKAP1, STAR
Short RNA molecules with high binding affinity to the KH motif of A-kinase anchoring protein 1 (AKAP1): implications for the regulation of steroidogenesis.
Grozdanov PN, Stocco DM.
Mol Endocrinol 26(12):2104-17. doi: 10.1210/me.2012-1123. Epub 2012 Oct 17. 2012
5AGT, STAR
Angiotensin II-dependent transcriptional activation of human steroidogenic acute regulatory protein gene by a 25-kDa cAMP-responsive element modulator protein isoform and Yin Yang 1.
Meier RK, Clark BJ.
Endocrinology 153(3):1256-68. doi: 10.1210/en.2011-1744. Epub 2012 Jan 17. 2012
6PDE8A, PDE8B, STAR
cAMP-specific phosphodiesterases 8A and 8B, essential regulators of Leydig cell steroidogenesis.
Shimizu-Albergine M, Tsai LC, Patrucco E, Beavo JA.
Mol Pharmacol 81(4):556-66. doi: 10.1124/mol.111.076125. Epub 2012 Jan 9. 2012
7CLAH, STAR
Congenital lipoid adrenal hyperplasia: functional characterization of three novel mutations in the STAR gene.
Bens S, Mohn A, Yüksel B, Kulle AE, Michalek M, Chiarelli F, Nuri Ozbek M, Leuschner I, Grötzinger J, Holterhus PM, Riepe FG.
J Clin Endocrinol Metab 95(3):1301-8. Epub 2010 Jan 15.PMID: 20080861 2010
8STAR
Mitochondrial cholesterol transporter, StAR, inhibits human THP-1 monocyte-derived macrophage apoptosis.
Bai Q, Li X, Ning Y, Zhao F, Yin L.
Lipids 45(1):29-36. Epub 2009 Nov 28.PMID: 19946756 2010
9CLAH, STAR
Clinical, genetic, and functional characterization of four patients carrying partial loss-of-function mutations in the steroidogenic acute regulatory protein (StAR).
Sahakitrungruang T, Soccio RE, Lang-Muritano M, Walker JM, Achermann JC, Miller WL.
J Clin Endocrinol Metab 95(7):3352-9. Epub 2010 May 5. 2010
10NR5A1, NR5A2, STAR
Identification of a novel distal control region upstream of the human steroidogenic acute regulatory protein (StAR) gene that participates in SF-1-dependent chromatin architecture.
Mizutani T, Yazawa T, Ju Y, Imamichi Y, Uesaka M, Inaoka Y, Matsuura K, Kamiki Y, Oki M, Umezawa A, Miyamoto K.
J Biol Chem 285(36):28240-51. Epub 2010 Jul 3. 2010
11PCTP, STAR, STARD3, STARD4, STARD5
Mammalian StAR-related lipid transfer (START) domains with specificity for cholesterol: structural conservation and mechanism of reversible binding.
Lavigne P, Najmanivich R, Lehoux JG.
Subcell Biochem 51:425-37. doi: 10.1007/978-90-481-8622-8_15. Review. 2010
12STAR
Steroidogenic acute regulatory protein has a more open conformation than the independently folded smaller subdomains.
Bose HS, Whittal RM, Debnath D, Bose M.
Biochemistry 48(49):11630-9.PMID: 19899816 2009
13FOXL2, STAR, UBE2I
Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene.
Kuo FT, Bentsi-Barnes IK, Barlow GM, Bae J, Pisarska MD.
Cell Signal 21(12):1935-44. Epub 2009 Sep 8.PMID: 19744555 2009
14STAR
Validation of the mechanism of cholesterol binding by StAR using short molecular dynamics simulations.
Barbar E, Lavigne P, Lehoux JG.
J Steroid Biochem Mol Biol 113(1-2):92-7. Epub 2008 Nov 27.PMID: 19095060 2009
15STAR, STARD3
Differential regulation of the STARD1 subfamily of START lipid trafficking proteins in human macrophages.
Borthwick F, Taylor JM, Bartholomew C, Graham A.
FEBS Lett 583(7):1147-53. Epub 2009 Mar 10. 2009
16STAR, STARD3
Cholesterol interaction with the related steroidogenic acute regulatory lipid-transfer (START) domains of StAR (STARD1) and MLN64 (STARD3).
Reitz J, Gehrig-Burger K, Strauss JF 3rd, Gimpl G.
FEBS J 275(8):1790-802. Epub 2008 Mar 7. 2008
17STAR
Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter.
Miller WL.
Biochim Biophys Acta 1771(6):663-76. Epub 2007 Mar 6. Review.PMID: 17433772 2007
18STAR
A novel mutation in the steroidogenic acute regulatory protein gene promoter leading to reduced promoter activity.
Casal AJ, Sinclair VJ, Capponi AM, Nicod J, Huynh-Do U, Ferrari P.
J Mol Endocrinol 37(1):71-80. 2006
19COL4A3BP, PCTP, STAR, STARD10, STARD3, STARD5
Give lipids a START: the StAR-related lipid transfer (START) domain in mammals.
Alpy F, Tomasetto C.
J Cell Sci 118(Pt 13):2791-801. Review. 2005
20STAR
Steroidogenic acute regulatory protein expression in the normal human brain and intracranial tumors.
Kim HJ, Kim JE, Ha M, Kang SS, Kim JT, Park IS, Paek SH, Jung HW, Kim DG, Cho GJ, Choi WS.
Brain Res 978(1-2):245-9. 2003
21STAR
Rapid regulation of steroidogenesis by mitochondrial protein import.
Bose H, Lingappa VR, Miller WL.
Nature 417(6884):87-91. 2002
22STAR, CLAH
Molecular and structural analysis of two novel star mutations in patients with lipoid congenital adrenal hyperplasia.
Achermann JC, Meeks JJ, Jeffs B, Das U, Clayton PE, Brook CG, Jameson JL.
Mol Genet Metab 73(4):354-7. 2001
23CEBPA, CEBPB, STAR
CCAAT/enhancer-binding proteins regulate expression of the human steroidogenic acute regulatory protein (StAR) gene.
Christenson LK, Johnson PF, McAllister JM, Strauss JF 3rd.
J Biol Chem 274(37):26591-8 1999
24STAR, CLAH
A novel compound heterozygous mutation in the steroidogenic acute regulatory protein gene in a patient with congenital lipoid adrenal hyperplasia.
Katsumata N, Kawada Y, Yamamoto Y, Noda M, Nimura A, Horikawa R, Tanaka T.
J Clin Endocrinol Metab 84(11):3983-7 1999
25STAR
Steroidogenic acute regulatory protein (StAR) is a sterol transfer protein.
Kallen CB, et al.
J Biol Chem 273 : 26285-26288. 1998
26STAR
Steroidogenic acute regulatory protein (StAR) acts on the outside of mitochondria to stimulate steroidogenesis.
Arakane F, et al.
Endocr Res 24(3-4):463-8. 1998
27STAR, CLAH
Analysis of the steroidogenic acute regulatory protein (StAR) gene in Japanese patients with congenital lipoid adrenal hyperplasia.
Nakae J, et al.
Hum Mol Genet 6 : 571-576. 1997
28STAR, CLAH
A novel splicing junction mutation in the gene for the steroidogenic acute regulatory protein causes congenital lipoid adrenal hyperplasia.
Okuyama E, Nishi N, Onishi S, Itoh S, Ishii Y, Miyanaka H, Fujita K, Ichikawa Y.
J Clin Endocrinol Metab 82(7):2337-42. 1997
29STAR, CLAH
Homozygous Q258X mutation in the steroidogenic acute regulatory gene in a Japanese patient with congenital lipoid adrenal hyperplasia.
Katsumata N, Tanae A, Shinagawa T, Nagashima-Miyokawa A, Shimizu M, Yasunaga T, Tanaka T, Hibi I.
Endocr J 44(3):441-6. 1997
30AHC, DAX1, NR0B1, NR0B2, STAR
DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis.
Zazopoulos E, Lalli E, Stocco DM, Sassone-Corsi P.
Nature 390(6657):311-5. 1997
31STAR, CLAH
T->A transversion 11 bp from a splice acceptor site in the human gene for steroidogenic acute regulatory protein causes congenital lipoid adrenal hyperplasia.
Tee MK, et al.
Hum Mol Genet 4 : 2299-2305. 1995
32STAR, STARP1
Structure of the human steroidogenic acute regulatory protein (StAR) gene : StAR stimulates mitochondrial cholesterol 27-hydroxylase activity.
Sugawara T, et al.
Biochemistry 34 : 12506-12512. 1995
33STAR
The human steroidogenic acute regulatory (StAR) gene is expressed in the urogenital system and encodes a mitochondrial polypeptide.
Gradi A, et al.
Biochim Biophys Acta 1258 : 228-233. 1995
34STAR, STARP1
Human steroidogenic acute regulatory protein : functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13.
Sugawara T, et al.
Proc Natl Acad Sci U S A 92 : 4778-4782. 1995