| 1 | MACROD2, PLD5, ST8SIA2 |
| A genome-wide scan for common alleles affecting risk for autism. | |
| Anney R, Klei L, Pinto D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Sykes N, Pagnamenta AT, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bölte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Carson AR, Casallo G, Casey J, Chu SH, Cochrane L, Corsello C, Crawford EL, Crossett A, Dawson G, de Jonge M, Delorme R, Drmic I, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Goldberg J, Green J, Guter SJ, Hakonarson H, Heron EA, Hill M, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Korvatska O, Kustanovich V, Lajonchere CM, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lionel AC, Liu XQ, Lord C, Lotspeich L, Lund SC, Maestrini E, Mahoney W, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Melhem NM, Merikangas A, Migita O, Minshew NJ, Mirza GK, Munson J, Nelson SF, Noakes C, Noor A, Nygren G, Oliveira G, Papanikolaou K, Parr JR, Parrini B, Paton T, Pickles A, Piven J, Posey DJ, Poustka A, Poustka F, Prasad A, Ragoussis J, Renshaw K, Rickaby J, Roberts W, Roeder K, Roge B, Rutter ML, Bierut LJ, Rice JP, Salt J, Sansom K, Sato D, Segurado R, Senman L, Shah N, Sheffield VC, Soorya L, Sousa I, Stoppioni V, Strawbridge C, Tancredi R, Tansey K, Thiruvahindrapduram B, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Wallace S, Wang K, Wang Z, Wassink TH, Wing K, Wittemeyer K, Wood S, Yaspan BL, Zurawiecki D, Zwaigenbaum L, Betancur C, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Gallagher L, Geschwind DH, Gill M, Haines JL, Miller J, Monaco AP, Nurnberger JI Jr, Paterson AD, Pericak-Vance MA, Schellenberg GD, Scherer SW, Sutcliffe JS, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Devlin B, Ennis S, Hallmayer J. | |
| Hum Mol Genet 19(20):4072-82. Epub 2010 Jul 27. 2010 | |
| 2 | ST8SIA2 |
| Divergent impact of the polysialyltransferases ST8SiaII and ST8SiaIV on polysialic acid expression in immature neurons and interneurons of the adult cerebral cortex. | |
| Nacher J, Guirado R, Varea E, Alonso-Llosa G, Röckle I, Hildebrandt H. | |
| Neuroscience 167(3):825-37. Epub 2010 Mar 3. 2010 | |
| 3 | ST8SIA2, ST8SIA4 |
| Identification of sequences in the polysialyltransferases ST8Sia II and ST8Sia IV that are required for the protein-specific polysialylation of the neural cell adhesion molecule, NCAM. | |
| Foley DA, Swartzentruber KG, Colley KJ. | |
| J Biol Chem 284(23):15505-16. Epub 2009 Mar 31. 2009 | |
| 4 | ST8SIA2, ST8SIA4 |
| Imbalance of neural cell adhesion molecule and polysialyltransferase alleles causes defective brain connectivity. | |
| Hildebrandt H, Mühlenhoff M, Oltmann-Norden I, Röckle I, Burkhardt H, Weinhold B, Gerardy-Schahn R. | |
| Brain 132(Pt 10):2831-8. Epub 2009 May 14. 2009 | |
| 5 | ST8SIA2, ST8SIA4 |
| Impact of the polysialyltransferases ST8SiaII and ST8SiaIV on polysialic acid synthesis during postnatal mouse brain development. | |
| Oltmann-Norden I, Galuska SP, Hildebrandt H, Geyer R, Gerardy-Schahn R, Geyer H, Mühlenhoff M. | |
| J Biol Chem 283(3):1463-71. Epub 2007 Nov 28. 2008 | |
| 6 | NCAM1,ST8SIA2,ST8SIA4 |
| Down-regulation of polysialic acid is required for efficient myelin formation. | |
| Fewou SN, Ramakrishnan H, Bussow H, Gieselmann V, Eckhardt M. | |
| J Biol Chem 282(22):16700-11. Epub 2007 Apr 9. 2007 | |
| 7 | ST8SIA1 , ST8SIA2, ST8SIA3, ST8SIA4 |
| Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III. | |
| Angata K, Suzuki M, McAuliffe J, Ding Y, Hindsgaul O, Fukuda M. | |
| J Biol Chem 275(24):18594-601. 2000 | |
| 8 | ST8SIA2, ST8SIA4 |
| Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule. | |
| Angata K, et al. | |
| J Biol Chem 272 : 7182-7190. 1997 | |
| 9 | ST8SIA2 |
| A human STX cDNA confers polysialic acid expression in mammalian cells. | |
| Scheidegger EP, et al. | |
| J Biol Chem 270(39):22685-8 1995 | |