| 1 | HGFAC, HPN, SPINT2, ST14
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| SPINT2 Deregulation in Prostate Carcinoma.
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| Pereira MS, de Almeida GC, Pinto F, Viana-Pereira M, Reis RM.
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| J Histochem Cytochem Histochem Cytochem. 2015 Oct 6. pii: 0022155415612874. [Epub ahead of print] 2015
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| 2 | SPINT2, ST14
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| HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase.
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| Tsai CH, Teng CH, Tu YT, Cheng TS, Wu SR, Ko CJ, Shyu HY, Lan SW, Huang HP, Tzeng SF, Johnson MD, Lin CY, Hsiao PW, Lee MS.
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| Oncogene 33(38):4643-52. doi: 10.1038/onc.2013.412. Epub 2013 Oct 14.
2014
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| 3 | PRSS8, ST14, TMPRSS11E, TMPRSS13, TMPRSS4
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| TMPRSS13 deficiency impairs stratum corneum formation and epidermal barrier acquisition.
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| Madsen DH, Szabo R, Molinolo AA, Bugge TH.
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| Biochem J 461(3):487-95. doi: 10.1042/BJ20140337.
2014
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| 4 | SPINT2, ST14
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| Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase.
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| Larsen BR, Steffensen SD, Nielsen NV, Friis S, Godiksen S, Bornholdt J, Soendergaard C, Nonboe AW, Andersen MN, Poulsen SS, Szabo R, Bugge TH, Lin CY, Skovbjerg H, Jensen JK, Vogel LK.
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| Exp Cell Res 319(6):918-29. doi: 10.1016/j.yexcr.2013.01.008. Epub 2013 Jan 16.
2013
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| 5 | ST14, TMPRSS11D, TMPRSS2
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| Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.
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| Baron J, Tarnow C, Mayoli-Nüssle D, Schilling E, Meyer D, Hammami M, Schwalm F, Steinmetzer T, Guan Y, Garten W, Klenk HD, Böttcher-Friebertshäuser E.
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| J Virol 87(3):1811-20. doi: 10.1128/JVI.02320-12. Epub 2012 Nov 28.
2013
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| 6 | PRSS8, SPINT1, ST14
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| Regulation of pericellular proteolysis by hepatocyte growth factor activator inhibitor type 1 (HAI-1) in trophoblast cells.
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| Kohama K, Kawaguchi M, Fukushima T, Lin CY, Kataoka H.
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| Hum Cell 25(4):100-10. doi: 10.1007/s13577-012-0055-2. Epub 2012 Dec 18.
2012
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| 7 | SPINT1, ST14
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| Cleavage of hepatocyte growth factor activator inhibitor-1 by membrane-type MMP-1 activates matriptase.
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| Domoto T, Takino T, Guo L, Sato H.
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| Cancer Sci 103(3):448-54. doi: 10.1111/j.1349-7006.2011.02162.x. Epub 2011 Dec 28.
2012
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| 8 | SPINT1, ST14
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| Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1.
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| Xu H, Xu Z, Tseng IC, Chou FP, Chen YW, Wang JK, Johnson MD, Kataoka H, Lin CY.
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| Am J Physiol Cell Physiol 302(2):C453-62. doi: 10.1152/ajpcell.00344.2011. Epub 2011 Oct 26.
2012
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| 9 | PRSS8, SPINT1, SPINT2, ST14
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| Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation.
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| Szabo R, Uzzun Sales K, Kosa P, Shylo NA, Godiksen S, Hansen KK, Friis S, Gutkind JS, Vogel LK, Hummler E, Camerer E, Bugge TH.
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| PLoS Genet 8(8):e1002937. doi: 10.1371/journal.pgen.1002937. Epub 2012 Aug 30.
2012
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| 10 | ST14, TEK
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| Epithin/PRSS14 proteolytically regulates angiopoietin receptor Tie2 during transendothelial migration.
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| Kim C, Lee HS, Lee D, Lee SD, Cho EG, Yang SJ, Kim SB, Park D, Kim MG.
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| Blood 117(4):1415-24. Epub 2010 Nov 19.
2011
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| 11 | ST14
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| PRSS14/Epithin is induced in macrophages by the IFN-γ/JAK/STAT pathway and mediates transendothelial migration.
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| Lee D, Lee HS, Yang SJ, Jeong H, Kim DY, Lee SD, Oh JW, Park D, Kim MG.
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| Biochem Biophys Res Commun 405(4):644-50. Epub 2011 Feb 2.
2011
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| 12 | PRSS8, ST14
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| Transport via the transcytotic pathway makes prostasin available as a substrate for matriptase.
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| Friis S, Godiksen S, Bornholdt J, Selzer-Plon J, Rasmussen HB, Bugge TH, Lin CY, Vogel LK.
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| J Biol Chem 286(7):5793-802. doi: 10.1074/jbc.M110.186874. Epub 2010 Dec 10.
2011
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| 13 | ST14
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| Epithin, a target of transforming growth factor-beta signaling, mediates epithelial-mesenchymal transition.
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| Lee HS, Kim C, Kim SB, Kim MG, Park D.
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| Biochem Biophys Res Commun 395(4):553-9. Epub 2010 Apr 14. 2010
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| 14 | ST14
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| ST14 Gene Variant and Decreased Matriptase Protein Expression Predict Poor Breast Cancer Survival.
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| Kauppinen JM, Kosma VM, Soini Y, Sironen R, Nissinen M, Nykopp TK, Kärjä V, Eskelinen M, Kataja V, Mannermaa A.
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| Cancer Epidemiol Biomarkers Prev ancer Epidemiol Biomarkers Prev. 2010 Aug 17. [Epub ahead of print]PMID: 20716618 2010
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| 15 | ST14
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| Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine.
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| Buzza MS, Netzel-Arnett S, Shea-Donohue T, Zhao A, Lin CY, List K, Szabo R, Fasano A, Bugge TH, Antalis TM.
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| Proc Natl Acad Sci U S A 107(9):4200-5. Epub 2010 Feb 8.PMID: 20142489 2010
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| 16 | ST14
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| Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway.
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| List K, Kosa P, Szabo R, Bey AL, Wang CB, Molinolo A, Bugge TH.
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| Am J Pathol 175(4):1453-63. Epub 2009 Aug 28.PMID: 19717635 2009
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| 17 | ST14
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| Matriptase-deficient mice exhibit ichthyotic skin with a selective shift in skin microbiota.
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| Scharschmidt TC, List K, Grice EA, Szabo R; NISC Comparative Sequencing Program, Renaud G, Lee CC, Wolfsberg TG, Bugge TH, Segre JA.
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| J Invest Dermatol 129(10):2435-42. Epub 2009 Apr 23.PMID: 19387477 2009
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| 18 | ARIH, ST14
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| Ichthyosis, follicular atrophoderma, and hypotrichosis caused by mutations in ST14 is associated with impaired profilaggrin processing.
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| Alef T, Torres S, Hausser I, Metze D, Türsen U, Lestringant GG, Hennies HC.
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| J Invest Dermatol 129(4):862-9. Epub 2008 Oct 9.PMID: 18843291 2009
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| 19 | SPINT1, ST14
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| Role of the stem domain of matriptase in the interaction with its physiological inhibitor, hepatocyte growth factor activator inhibitor type I.
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| Kojima K, Tsuzuki S, Fushiki T, Inouye K.
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| J Biochem 145(6):783-90. doi: 10.1093/jb/mvp036. Epub 2009 Mar 10.
2009
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| 20 | HPN, ST14, TMPRSS11E, TMPRSS6
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| Probing the substrate specificities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched fluorescent peptides.
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| Béliveau F, Désilets A, Leduc R.
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| FEBS J 276(8):2213-26. doi: 10.1111/j.1742-4658.2009.06950.x. Epub 2009 Mar 3.
2009
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| 21 | ARIH, ST14
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| Autosomal recessive ichthyosis with hypotrichosis syndrome: further delineation of the phenotype.
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| Avrahami L, Maas S, Pasmanik-Chor M, Rainshtein L, Magal N, Smitt J, van Marle J, Shohat M, Basel-Vanagaite L.
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| Clin Genet 74(1):47-53. Epub 2008 Apr 28.
2008
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| 22 | PRSS8, SPINT1, ST14
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| Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary.
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| Godiksen S, Selzer-Plon J, Pedersen ED, Abell K, Rasmussen HB, Szabo R, Bugge TH, Vogel LK.
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| Biochem J 413(2):251-9. doi: 10.1042/BJ20071496.
2008
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| 23 | ARIH, ST14
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| Autosomal Recessive Ichthyosis with Hypotrichosis Caused by a Mutation in ST14, Encoding Type II Transmembrane Serine Protease Matriptase.
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| Basel-Vanagaite L, Attia R, Ishida-Yamamoto A, Rainshtein L, Ben Amitai D, Lurie R, Pasmanik-Chor M, Indelman M, Zvulunov A, Saban S, Magal N, Sprecher E, Shohat M.
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| Am J Hum Genet 80(3):467-77. Epub 2007 Jan 23. 2007
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| 24 | ST14
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| The novel serine protease tumor-associated differentially expressed gene-15 (matriptase/MT-SP1) is highly overexpressed in cervical carcinoma.
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| Santin AD, Cane' S, Bellone S, Bignotti E, Palmieri M, De Las Casas LE, Anfossi S, Roman JJ, O'Brien T, Pecorelli S.
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| Cancer 98(9):1898-904. 2003
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| 25 | ST14
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| Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase.
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| Benaud C, Oberst M, Hobson JP, Spiegel S, Dickson RB, Lin CY.
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| J Biol Chem 277(12):10539-46. 2002
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| 26 | ST14
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| Ovarian tumor cells express a transmembrane serine protease: a potential candidate for early diagnosis and therapeutic intervention.
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| Tanimoto H, Underwood LJ, Wang Y, Shigemasa K, Parmley TH, O'Brien TJ.
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| Tumour Biol 22(2):104-14. 2001
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| 27 | ST14
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| Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease.
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| Lee SL, Dickson RB, Lin CY.
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| J Biol Chem 275(47):36720-5. 2000
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| 28 | ST14
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| Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates.
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| Takeuchi T, Harris JL, Huang W, Yan KW, Coughlin SR, Craik CS.
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| J Biol Chem 275(34):26333-42. 2000
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| 29 | ST14
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| Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue.
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| Takeuchi T, Shuman MA, Craik CS.
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| Proc Natl Acad Sci U S A 96(20):11054-61. 1999
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| 30 | ST14
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| Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk.
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| Lin CY, Anders J, Johnson M, Dickson RB.
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| J Biol Chem 274(26):18237-42. 1999
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| 31 | ST14
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| Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity.
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| Lin CY, Anders J, Johnson M, Sang QA, Dickson RB.
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| J Biol Chem 274(26):18231-6.PMID: 10373424 1999
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| 32 | ST13, ST14
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| Assignment1 of human putative tumor suppressor genes ST13 (alias SNC6) and ST14 (alias SNC19) to human chromosome bands 22q13 and 11q24-->q25 by in situ hybridization.
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| Zhang Y, Cai X, Schlegelberger B, Zheng S.
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| Cytogenet Cell Genet 83(1-2):56-7. No abstract available. 1998
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| 33 | ST13, ST14
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| Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screening.
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| Cao J, et al.
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| J Cancer Res Clin Oncol 123(8):447-51. 1997
|