Citations for
1MED1, MED14, MED4, SSX2
A functional genetic screen identifies the Mediator complex as essential for SSX2-induced senescence
Brückmann NH, Bennedsen SN, Duijf PHG, Terp MG, Thomassen M, Larsen M, Pedersen CB, Kruse T, Alcaraz N, Ditzel HJ, Gjerstorff MF
Cell Death Dis. Nov 6;10(11):841. doi: 10.1038/s41419-019-2068-1. 2019
2SS18, SSX2
Epigenetic Targets in Synovial Sarcoma: A Mini-Review.
Hale R, Sandakly S, Shipley J, Walters Z.
Front Oncol. Oct 18;9:1078. doi: 10.3389/fonc.2019.01078. eCollection 2 2019
3SS18, SSX1, SSX2
Proteomic signatures corresponding to the SS18/SSX fusion gene in synovial sarcoma.
Ishii M, Suehara Y, Sano K, Kohsaka S, Hayashi T, Kazuno S, Akaike K, Mukaihara K, Kim Y, Okubo T, Takamochi K, Takahashi F, Kaneko K, Saito T.
Oncotarget Dec 25;9(101):37509-37519. doi: 10.18632/oncotarget.26493. eCollection 2018 Dec 25 2018
4SSX2
SSX2 regulates focal adhesion but does not drive the epithelial to mesenchymal transition in prostate cancer
Bloom JE, McNeel DG.
Oncotarget. Aug 9;7(32):50997-51011. doi: 10.18632/oncotarget.9802. 2016
5SSX2
Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability.
Greve KB, Lindgreen JN, Terp MG, Pedersen CB, Schmidt S, Mollenhauer J, Kristensen SB, Andersen RS, Relster MM, Ditzel HJ, Gjerstorff MF.
Mol Oncol. Feb;9(2):437-49. doi: 10.1016/j.molonc.2014.09.001. Epub 2014 Oct 6. 2015
6SSX2
SSX2 is a novel DNA-binding protein that antagonizes polycomb group body formation and gene repression.
Gjerstorff MF, Relster MM, Greve KB, Moeller JB, Elias D, Lindgreen JN, Schmidt S, Mollenhauer J, Voldborg B, Pedersen CB, Brückmann NH, Mĝllegaard NE, Ditzel HJ.
Nucleic Acids Res. Oct;42(18):11433-46. doi: 10.1093/nar/gku852. Epub 2014 Sep 23. 2014
7SS18, SSX2
SS18-SSX2 and the mitochondrial apoptosis pathway in mouse and human synovial sarcomas
Underhill TM, Nielsen TO, Sharma S, Capecchi MR
Oncogene. May 2;32(18):2365-71, 2375.e1-5. doi: 10.1038/onc.2012.247. Epub 2012 Jul 16. 2013
8SS18, SSX1, SSX2, IGF1R
Differential roles of SS18-SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth.
Tšrnkvist M, Natalishvili N, Xie Y, Girnita A, D'Arcy P, Brodin B, Axelson M, Girnita L.
Biochem Biophys Res Commun 368(3):793-800. Epub 2008 Feb 11. 2008
9SS18, SSX1, SSX2
Gene expression profiles relate to SS18/SSX fusion type in synovial sarcoma.
Fernebro J, Francis P, EdŽn P, Borg A, Panagopoulos I, Mertens F, Vallon-Christersson J, Akerman M, Rydholm A, Bauer HC, Mandahl N, Nilbert M.
Int J Cancer 118(5):1165-72. 2006
10SSX2, SSX5
Expression of cancer-testis antigen (CTA) in tumor tissues and peripheral blood of Chinese patients with hepatocellular carcinoma.
Wu LQ, Lu Y, Wang XF, Lv ZH, Zhang B, Yang JY.
Life Sci 79(8):744-8. Epub 2006 Feb 28. 2006
11SSX2, SS18
Splicing isoform of SYT-SSX fusion protein accelerates transcriptional activity and cell proliferation.
Morimoto Y, Ouchida M, Ozaki T, Kawai A, Ito T, Yoshida A, Inoue H, Shimizu K.
Cancer Lett 199(1):35-43. 2003
12RAB3IP, SSX1, SSX2, SSX2IP, SSX3
The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
de Bruijn DR, dos Santos NR, Kater-Baats E, Thijssen J, van den Berk L, Stap J, Balemans M, Schepens M, Merkx G, van Kessel AG.
Genes Chromosomes Cancer 34(3):285-98. 2002
13SSX1, SSX2, SSX2B, SSX3, SSX4, SSX5, SSX6, SSX7, SSX8, SSX9, SSXP1, SSXP10, SSXP2, SSXP3, SSXP4, SSXP5, SSXP6, SSXP7, SSXP8, SSXP9
The SSX gene family: characterization of 9 complete genes.
Gure AO, Wei IJ, Old LJ, Chen YT.
Int J Cancer 101(5):448-53. 2002
14SSX1, SSX2, SSX3, SSX4, SSX5, SSX6
Molecular mechanisms underlying human synovial sarcoma development.
dos Santos NR, de Bruijn DR, van Kessel AG.
Genes Chromosomes Cancer 30(1):1-14. 2001
15SSX1, SSX2, SS18
Delineation of the protein domains responsible for SYT, SSX, and SYT-SSX nuclear localization.
dos Santos NR, de Bruijn DR, Kater-Baats E, Otte AP, van Kessel AG.
Exp Cell Res 256(1):192-202. 2000
16SS18, SSX1, SSX2
Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus.
Thaete C, et al.
Hum Mol Genet 8(4):585-91. 1999
17SSX1, SSX2, SS18
SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma.
Kawai A, Woodruff J, Healey JH, Brennan MF, Antonescu CR, Ladanyi M.
N Engl J Med 338(3):153-60. 1998
18BSSX, SSX1, SSX2, SS18
A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas.
Lim FL, Soulez M, Koczan D, Thiesen HJ, Knight JC.
Oncogene 17 : 2013-2018. 1998
19SSX1, SSX2, SS18
Nuclear localization of SYT, SSX and the synovial sarcoma-associated SYT-SSX fusion proteins.
dos Santos NR, de Bruijn DR, Balemans M, Janssen B, Gartner F, Lopes JM, de Leeuw B, Geurts van Kessel A.
Hum Mol Genet 6(9):1549-58. 1997
20SSX1, SSX2, SSX3, SSX4, SSX5
SSX: a multigene family with several members transcribed in normal testis and human cancer.
Gure AO, Tureci O, Sahin U, Tsang S, Scanlan MJ, Jager E, Knuth A, Pfreundschuh M, Old LJ, Chen YT.
Int J Cancer 72(6):965-71. 1997
21SSX2
The SSX-2 gene, which is involved in the t(X;18) translocation of synovial sarcomas, codes for the human tumor antigen HOM-MEL-40.
TŸreci …, et al.
Cancer Res 56 : 4766-4772. 1996
22BSSX, SSX1, SSX2
Two categories of synovial sarcoma defined by divergent chromosome translocation breakpoints in Xp11.2, with implications for the histologic sub-classification of synovial sarcoma.
Renwick PJ, et al.
Cytogenet Cell Genet 70 : 58-63. 1995
23BSSX, SSX1, SSX2, SS18
Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.
Crew AJ, et al.
EMBO J 14 : 2333-2340. 1995
24BSSX, SS18, SSX1, SSX2
Identification of two alternative fusion genes, SYT-SSX1 and SYT-SSX2, in t(X;18)(p11.2;q11.2)-positive synovial sarcomas.
de Leeuw B, et al.
Hum Mol Genet 4 : 1097-1099. 1995