1 | MED1, MED14, MED4, SSX2
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| A functional genetic screen identifies the Mediator complex as essential for SSX2-induced senescence
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| Brückmann NH, Bennedsen SN, Duijf PHG, Terp MG, Thomassen M, Larsen M, Pedersen CB, Kruse T, Alcaraz N, Ditzel HJ, Gjerstorff MF
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| Cell Death Dis. Nov 6;10(11):841. doi: 10.1038/s41419-019-2068-1. 2019
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2 | SS18, SSX2
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| Epigenetic Targets in Synovial Sarcoma: A Mini-Review.
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| Hale R, Sandakly S, Shipley J, Walters Z.
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| Front Oncol. Oct 18;9:1078. doi: 10.3389/fonc.2019.01078. eCollection 2 2019
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3 | SS18, SSX1, SSX2
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| Proteomic signatures corresponding to the SS18/SSX fusion gene in synovial sarcoma.
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| Ishii M, Suehara Y, Sano K, Kohsaka S, Hayashi T, Kazuno S, Akaike K, Mukaihara K, Kim Y, Okubo T, Takamochi K, Takahashi F, Kaneko K, Saito T.
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| Oncotarget Dec 25;9(101):37509-37519. doi: 10.18632/oncotarget.26493. eCollection 2018 Dec 25 2018
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4 | SSX2
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| SSX2 regulates focal adhesion but does not drive the epithelial to mesenchymal transition in prostate cancer
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| Bloom JE, McNeel DG.
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| Oncotarget. Aug 9;7(32):50997-51011. doi: 10.18632/oncotarget.9802. 2016
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5 | SSX2
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| Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability.
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| Greve KB, Lindgreen JN, Terp MG, Pedersen CB, Schmidt S, Mollenhauer J, Kristensen SB, Andersen RS, Relster MM, Ditzel HJ, Gjerstorff MF.
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| Mol Oncol. Feb;9(2):437-49. doi: 10.1016/j.molonc.2014.09.001. Epub 2014 Oct 6. 2015
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6 | SSX2
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| SSX2 is a novel DNA-binding protein that antagonizes polycomb group body formation and gene repression.
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| Gjerstorff MF, Relster MM, Greve KB, Moeller JB, Elias D, Lindgreen JN, Schmidt S, Mollenhauer J, Voldborg B, Pedersen CB, Brückmann NH, Mĝllegaard NE, Ditzel HJ.
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| Nucleic Acids Res. Oct;42(18):11433-46. doi: 10.1093/nar/gku852. Epub 2014 Sep 23. 2014
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7 | SS18, SSX2
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| SS18-SSX2 and the mitochondrial apoptosis pathway in mouse and human synovial sarcomas
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| Underhill TM, Nielsen TO, Sharma S, Capecchi MR
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| Oncogene. May 2;32(18):2365-71, 2375.e1-5. doi: 10.1038/onc.2012.247. Epub 2012 Jul 16. 2013
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8 | SS18, SSX1, SSX2, IGF1R
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| Differential roles of SS18-SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth.
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| Trnkvist M, Natalishvili N, Xie Y, Girnita A, D'Arcy P, Brodin B, Axelson M, Girnita L.
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| Biochem Biophys Res Commun 368(3):793-800. Epub 2008 Feb 11. 2008
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9 | SS18, SSX1, SSX2
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| Gene expression profiles relate to SS18/SSX fusion type in synovial sarcoma.
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| Fernebro J, Francis P, Edn P, Borg A, Panagopoulos I, Mertens F, Vallon-Christersson J, Akerman M, Rydholm A, Bauer HC, Mandahl N, Nilbert M.
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| Int J Cancer 118(5):1165-72. 2006
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10 | SSX2, SSX5
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| Expression of cancer-testis antigen (CTA) in tumor tissues and peripheral blood of Chinese patients with hepatocellular carcinoma.
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| Wu LQ, Lu Y, Wang XF, Lv ZH, Zhang B, Yang JY.
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| Life Sci 79(8):744-8. Epub 2006 Feb 28.
2006
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11 | SSX2, SS18
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| Splicing isoform of SYT-SSX fusion protein accelerates transcriptional activity and cell proliferation.
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| Morimoto Y, Ouchida M, Ozaki T, Kawai A, Ito T, Yoshida A, Inoue H, Shimizu K.
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| Cancer Lett 199(1):35-43. 2003
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12 | RAB3IP, SSX1, SSX2, SSX2IP, SSX3
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| The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
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| de Bruijn DR, dos Santos NR, Kater-Baats E, Thijssen J, van den Berk L, Stap J, Balemans M, Schepens M, Merkx G, van Kessel AG.
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| Genes Chromosomes Cancer 34(3):285-98. 2002
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13 | SSX1, SSX2, SSX2B, SSX3, SSX4, SSX5, SSX6, SSX7, SSX8, SSX9, SSXP1, SSXP10, SSXP2, SSXP3, SSXP4, SSXP5, SSXP6, SSXP7, SSXP8, SSXP9
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| The SSX gene family: characterization of 9 complete genes.
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| Gure AO, Wei IJ, Old LJ, Chen YT.
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| Int J Cancer 101(5):448-53. 2002
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14 | SSX1, SSX2, SSX3, SSX4, SSX5, SSX6
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| Molecular mechanisms underlying human synovial sarcoma development.
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| dos Santos NR, de Bruijn DR, van Kessel AG.
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| Genes Chromosomes Cancer 30(1):1-14. 2001
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15 | SSX1, SSX2, SS18
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| Delineation of the protein domains responsible for SYT, SSX, and SYT-SSX nuclear localization.
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| dos Santos NR, de Bruijn DR, Kater-Baats E, Otte AP, van Kessel AG.
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| Exp Cell Res 256(1):192-202. 2000
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16 | SS18, SSX1, SSX2
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| Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus.
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| Thaete C, et al.
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| Hum Mol Genet 8(4):585-91. 1999
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17 | SSX1, SSX2, SS18
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| SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma.
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| Kawai A, Woodruff J, Healey JH, Brennan MF, Antonescu CR, Ladanyi M.
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| N Engl J Med 338(3):153-60. 1998
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18 | BSSX, SSX1, SSX2, SS18
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| A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas.
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| Lim FL, Soulez M, Koczan D, Thiesen HJ, Knight JC.
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| Oncogene 17 : 2013-2018. 1998
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19 | SSX1, SSX2, SS18
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| Nuclear localization of SYT, SSX and the synovial sarcoma-associated SYT-SSX fusion proteins.
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| dos Santos NR, de Bruijn DR, Balemans M, Janssen B, Gartner F, Lopes JM, de Leeuw B, Geurts van Kessel A.
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| Hum Mol Genet 6(9):1549-58. 1997
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20 | SSX1, SSX2, SSX3, SSX4, SSX5
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| SSX: a multigene family with several members transcribed in normal testis and human cancer.
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| Gure AO, Tureci O, Sahin U, Tsang S, Scanlan MJ, Jager E, Knuth A, Pfreundschuh M, Old LJ, Chen YT.
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| Int J Cancer 72(6):965-71. 1997
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21 | SSX2
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| The SSX-2 gene, which is involved in the t(X;18) translocation of synovial sarcomas, codes for the human tumor antigen HOM-MEL-40.
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| Treci
, et al.
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| Cancer Res 56 : 4766-4772. 1996
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22 | BSSX, SSX1, SSX2
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| Two categories of synovial sarcoma defined by divergent chromosome translocation breakpoints in Xp11.2, with implications for the histologic sub-classification of synovial sarcoma.
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| Renwick PJ, et al.
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| Cytogenet Cell Genet 70 : 58-63. 1995
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23 | BSSX, SSX1, SSX2, SS18
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| Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.
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| Crew AJ, et al.
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| EMBO J 14 : 2333-2340. 1995
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24 | BSSX, SS18, SSX1, SSX2
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| Identification of two alternative fusion genes, SYT-SSX1 and SYT-SSX2, in t(X;18)(p11.2;q11.2)-positive synovial sarcomas.
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| de Leeuw B, et al.
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| Hum Mol Genet 4 : 1097-1099. 1995
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