Citations for
SS18 regulates pluripotent-somatic transition through phase separation.
Kuang J, Zhai Z, Li P, Shi R, Guo W, Yao Y, Guo J, Zhao G, He J, Xu S, Wu C, Yu S, Zhou C, Wu L, Qin Y, Cai B, Li W, Wu Z, Li X, Chu S, Yang T, Wang B, Cao S, Li D, Zhang X, Chen J, Liu J, Pei D
Nat Commun. Jul 2;12(1):4090. doi: 10.1038/s41467-021-24373-5. 2021
2HDAC2, SS18
HDAC2 links ubiquitination to tumor suppression in synovial sarcoma.
Cooley C, Su L.
Mol Cell Oncol. Apr 25;8(3):1914291. doi: 10.1080/23723556.2021.1914291. 2021
3NEDD4, SS18
Novel SS18-NEDD4 gene fusion in a primary renal synovial sarcoma
Argani P, Zhang L, Sung YS, Bacchi C, Swanson D, Dickson BC, Antonescu CR.
Genes Chromosomes Cancer. Mar;59(3):203-208. doi: 10.1002/gcc.22814. Epub 2019 Oct 21. 2020
4SS18, SSX2
Epigenetic Targets in Synovial Sarcoma: A Mini-Review.
Hale R, Sandakly S, Shipley J, Walters Z.
Front Oncol. Oct 18;9:1078. doi: 10.3389/fonc.2019.01078. eCollection 2 2019
5SS18, SSX1, SSX2
Proteomic signatures corresponding to the SS18/SSX fusion gene in synovial sarcoma.
Ishii M, Suehara Y, Sano K, Kohsaka S, Hayashi T, Kazuno S, Akaike K, Mukaihara K, Kim Y, Okubo T, Takamochi K, Takahashi F, Kaneko K, Saito T.
Oncotarget Dec 25;9(101):37509-37519. doi: 10.18632/oncotarget.26493. eCollection 2018 Dec 25 2018
Identification of SHCBP1 as a novel downstream target gene of SS18-SSX1 and its functional analysis in progression of synovial sarcoma.
Peng C, Zhao H, Chen W, Song Y, Wang X, Li J, Qiao Y, Wu D, Ma S, Wang X, Gao C.
Oncotarget. Oct 11;7(41):66822-66834. doi: 10.18632/oncotarget.11651. 2016
7SS18, SSX2
SS18-SSX2 and the mitochondrial apoptosis pathway in mouse and human synovial sarcomas
Underhill TM, Nielsen TO, Sharma S, Capecchi MR
Oncogene. May 2;32(18):2365-71, 2375.e1-5. doi: 10.1038/onc.2012.247. Epub 2012 Jul 16. 2013
8NCOA3, SS18, SSX1
SYT-SSX1 (synovial sarcoma translocated) regulates PIASy ligase activity to cause overexpression of NCOA3 protein.
Sun Y, Perera J, Rubin BP, Huang J.
J Biol Chem 286(21):18623-32. Epub 2011 Mar 24. 2011
9SS18, USP6
Unknown partner for USP6 and unusual SS18 rearrangement detected by fluorescence in situ hybridization in a solid aneurysmal bone cyst.
Geiersbach K, Rector LS, Sederberg M, Hooker A, Randall RL, Schiffman JD, South ST.
Cancer Genet 204(4):195-202. doi: 10.1016/j.cancergen.2011.01.004. 2011
10SS18, SSX1, SSX2, IGF1R
Differential roles of SS18-SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth.
Törnkvist M, Natalishvili N, Xie Y, Girnita A, D'Arcy P, Brodin B, Axelson M, Girnita L.
Biochem Biophys Res Commun 368(3):793-800. Epub 2008 Feb 11. 2008
11SS18, SSX1
The oncoprotein SS18-SSX1 promotes p53 ubiquitination and degradation by enhancing HDM2 stability.
D'Arcy P, Maruwge W, Ryan BA, Brodin B.
Mol Cancer Res 6(1):127-38. 2008
12LHX4, SS18
The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4.
de Bruijn DR, van Dijk AH, Willemse MP, van Kessel AG.
Oncogene 27(5):653-62. Epub 2007 Jul 30.PMID: 17667940 2008
13SS18, SSX1
The oncoprotein SS18-SSX1 promotes p53 ubiquitination and degradation by enhancing HDM2 stability.
D'Arcy P, Maruwge W, Ryan BA, Brodin B.
Mol Cancer Res 6(1):127-38.PMID: 18234968 2008
14SS18, SSX1, SSX2
Gene expression profiles relate to SS18/SSX fusion type in synovial sarcoma.
Fernebro J, Francis P, Edén P, Borg A, Panagopoulos I, Mertens F, Vallon-Christersson J, Akerman M, Rydholm A, Bauer HC, Mandahl N, Nilbert M.
Int J Cancer 118(5):1165-72. 2006
DNA pooling analysis of ADHD and genes regulating vesicle release of neurotransmitters.
Brookes KJ, Knight J, Xu X, Asherson P.
Am J Med Genet B Neuropsychiatr Genet 139(1):33-7. 2005
16CDKN1A, SSX1, SS18
Induction of p21(WAF1/CIP1) by human synovial sarcoma-associated chimeric oncoprotein SYT-SSX1.
Tsuda M, Watanabe T, Seki T, Kimura T, Sawa H, Minami A, Akagi T, Isobe K, Nagashima K, Tanaka S.
Oncogene 24(54):7984-90. 2005
17SSX2, SS18
Splicing isoform of SYT-SSX fusion protein accelerates transcriptional activity and cell proliferation.
Morimoto Y, Ouchida M, Ozaki T, Kawai A, Ito T, Yoshida A, Inoue H, Shimizu K.
Cancer Lett 199(1):35-43. 2003
Analysis of transforming activity of human synovial sarcoma-associated chimeric protein SYT-SSX1 bound to chromatin remodeling factor hBRM/hSNF2 alpha.
Nagai M, Tanaka S, Tsuda M, Endo S, Kato H, Sonobe H, Minami A, Hiraga H, Nishihara H, Sawa H, Nagashima K.
Proc Natl Acad Sci U S A 98(7):3843-8. 2001
Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT expression.
Brodin B, Haslam K, Yang K, Bartolazzi A, Xie Y, Starborg M, Lundeberg J, Larsson O.
Gene 268(1-2):173-82. 2001
Identification of a novel spliced variant of the SYT gene expressed in normal tissues and in synovial sarcoma.
Tamborini E, Agus V, Mezzelani A, Riva C, Sozzi G, Azzarelli A, Pierotti MA, Pilotti S.
Br J Cancer 84(8):1087-94. 2001
21SS18, SSX1
SYT-SSX fusion genes and prognosis in synovial sarcoma.
Mezzelani A, Mariani L, Tamborini E, Agus V, Riva C, Lo Vullo S, Fabbri A, Stumbo M, Azzarelli A, Casali PG, Gronchi A, Sozzi G, Pierotti MA, Pilotti S.
Br J Cancer 85(10):1535-9. 2001
22SSX1, SSX2, SS18
Delineation of the protein domains responsible for SYT, SSX, and SYT-SSX nuclear localization.
dos Santos NR, de Bruijn DR, Kater-Baats E, Otte AP, van Kessel AG.
Exp Cell Res 256(1):192-202. 2000
23SS18, SSX1, SSX2
Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus.
Thaete C, et al.
Hum Mol Genet 8(4):585-91. 1999
Primary synovial sarcoma of the lung: report of two cases confirmed by molecular detection of SYT-SSX fusion gene transcripts.
Hisaoka M, et al.
Histopathology 34(3):205-10. 1999
SSX and the synovial-sarcoma-specific chimaeric protein SYT-SSX co-localize with the human Polycomb group complex.
Soulez M, et al.
Oncogene 18(17):2739-46. 1999
26SSX1, SSX2, SS18
SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma.
Kawai A, Woodruff J, Healey JH, Brennan MF, Antonescu CR, Ladanyi M.
N Engl J Med 338(3):153-60. 1998
27BSSX, SSX1, SSX2, SS18
A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas.
Lim FL, Soulez M, Koczan D, Thiesen HJ, Knight JC.
Oncogene 17 : 2013-2018. 1998
Characterization of a variant SYT-SSX1 synovial sarcoma fusion transcript.
Safar A, et al.
Diagn Mol Pathol 7(5):283-7. 1998
29SSX1, SSX2, SS18
Nuclear localization of SYT, SSX and the synovial sarcoma-associated SYT-SSX fusion proteins.
dos Santos NR, de Bruijn DR, Balemans M, Janssen B, Gartner F, Lopes JM, de Leeuw B, Geurts van Kessel A.
Hum Mol Genet 6(9):1549-58. 1997
The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies.
Brett D, Whitehouse S, Antonson P, Shipley J, Cooper C, Goodwin G.
Hum Mol Genet 6(9):1559-64. 1997
31BSSX, SSX1, SSX2, SS18
Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.
Crew AJ, et al.
EMBO J 14 : 2333-2340. 1995
32BSSX, SS18, SSX1, SSX2
Identification of two alternative fusion genes, SYT-SSX1 and SYT-SSX2, in t(X;18)(p11.2;q11.2)-positive synovial sarcomas.
de Leeuw B, et al.
Hum Mol Genet 4 : 1097-1099. 1995
Sublocalisation of the t(X;18)(p11.2;q11.2) translocation breakpoint in synovial sarcoma.
Clark J, et al.
Cytogenet Cell Genet 65 : 164. 1994
Two distinct translocation breakpoints in t(X;18)-positive synovial sarcomas and their sub-localization.
de Leeuw B, et al.
Cytogenet Cell Genet 65 : 164. 1994
35BSSX, SS18
Molecular cloning of the synovial sarcoma-specific translocation (X;18)(p11.2;q11.2) breakpoint.
de Leeuw B, et al.
Hum Mol Genet 3 : 745-749. 1994
36BSSX, SS18
Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma.
Clark J, et al.
Nat Genet 7 : 502-508. 1994