| 1 | SPRR1A, SPRR1B
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| Small proline-rich proteins (SPRRs) are epidermally produced antimicrobial proteins that defend the cutaneous barrier by direct bacterial membrane disruption.
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| Zhang C, Hu Z, Lone AG, Artami M, Edwards M, Zouboulis CC, Stein M, Harris-Tryon TA.
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| Elife. Mar 2;11:e76729. doi: 10.7554/eLife.76729. 2022
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| 2 | RASSF4, SPRR1B
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| Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.
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| Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Fujino J, Tamura Y, Tsukahara T, Kanaseki T, Kobayashi J, Sasaki T, Takahashi A, Nakamori K, Yamaguchi A, Hiratsuka H, Sato N.
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| Biochem Biophys Res Commun 439(1):96-102. doi: 10.1016/j.bbrc.2013.08.021. Epub 2013 Aug 13.
2013
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| 3 | SPRR1A, SPRR1B, SPRR3, SPRR4
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| Study of small proline-rich proteins (SPRRs) in health and disease: a review of the literature.
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| Carregaro F, Stefanini AC, Henrique T, Tajara EH.
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| Arch Dermatol Res 305(10):857-66. doi: 10.1007/s00403-013-1415-9. Epub 2013 Oct 2. Review.
2013
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| 4 | SPRR1A, SPRR1B, SPRR3, SPRR4
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| Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families.
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| Kainu K, Kivinen K, Zucchelli M, Suomela S, Kere J, Inerot A, Baker BS, Powles AV, Fry L, Samuelsson L, Saarialho-Kere U.
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| Exp Dermatol 18(2):109-15. doi: 10.1111/j.1600-0625.2008.00769.x. Epub 2008 Jul 17.
2009
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| 5 | SPRR1B
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| Small proline-rich protein 1B (SPRR1B) is a biomarker for squamous metaplasia in dry eye disease.
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| Li S, Nikulina K, DeVoss J, Wu AJ, Strauss EC, Anderson MS, McNamara NA.
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| Invest Ophthalmol Vis Sci 49(1):34-41. doi: 10.1167/iovs.07-0685.
2008
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| 6 | SPRR1B
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| SPRR1B overexpression enhances entry of cells into the G0 phase of the cell cycle.
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| Tesfaigzi Y, Wright PS, Belinsky SA.
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| Am J Physiol Lung Cell Mol Physiol 285(4):L889-98. Epub 2003 Jun 27.
2003
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| 7 | SPRR1B
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| BMK1 (ERK5) regulates squamous differentiation marker SPRR1B transcription in Clara-like H441 cells.
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| Reddy SP, Adiseshaiah P, Shapiro P, Vuong H.
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| Am J Respir Cell Mol Biol 27(1):64-70.
2002
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| 8 | LCE1A, LCE1B, LCE1C, LCE1D, LCE1E, LCE1F, LCE2A, LCE2B, LCE2C, LCE2D, LCE3A, LCE3B, LCE3C, LCE3D, LCE3E, LCE4A, LCE5A, SPRR1B
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| Differentially expressed late constituents of the epidermal cornified envelope.
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| Marshall D, Hardman MJ, Nield KM, Byrne C.
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| Proc Natl Acad Sci U S A 98(23):13031-6. 2001
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| 9 | C1orf46, EDC@, SPRR1B
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| Positional cloning of novel skin-specific genes from the human epidermal differentiation complex.
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| Zhao XP, Elder JT.
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| Genomics 45(2):250-8. 1997
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| 10 | FLG, IVL, LOR, S100A10, S100A6, S100A8, S100A9, SPRR1B, SPRR2A, SPRR3, TCHH
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| Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex (epidermal differentiation complex) on human chromosome 1q21.
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| Mischke D, Korge BP, Marenholz I, Volz A, Ziegler A.
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| J Invest Dermatol 106 : 989-992. 1996
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| 11 | SPRR1A, SPRR1B, SPRR2A, SPRR2B, SPRR2C, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3
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| Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins.
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| Gibbs S, et al.
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| Genomics 16 : 630-637. 1993
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| 12 | SPRR1B
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| Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids.
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| Marvin KW, et al.
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| Proc Natl Acad Sci U S A 89 : 11026-11030. 1992
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