| 1 | CDK11A, GADD45A, GADD45G, SPDEF
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| GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration.
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| Tamura RE, Paccez JD, Duncan KC, Morale MG, Simabuco FM, Dillon S, Correa RG, Gu X, Libermann TA, Zerbini LF.
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| Oncotarget 7(12):13865-79. doi: 10.18632/oncotarget.7355.
2016
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| 2 | SPDEF
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| The transcription factor SPDEF suppresses prostate tumor metastasis.
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| Steffan JJ, Koul S, Meacham RB, Koul HK.
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| J Biol Chem 287(35):29968-78. doi: 10.1074/jbc.M112.379396. Epub 2012 Jul 2.
2012
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| 3 | ATOH1, SPDEF
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| The role of atoh1 in mucous cell metaplasia.
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| Nakamura Y, Hamajima Y, Komori M, Yokota M, Suzuki M, Lin J.
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| Int J Otolaryngol 2012:438609. doi: 10.1155/2012/438609. Epub 2012 Feb 14.
2012
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| 4 | SPDEF
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| Prostate derived ETS factor (PDEF): a putative tumor metastasis suppressor.
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| Steffan JJ, Koul HK.
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| Cancer Lett 310(1):109-17. Epub 2011 Jun 29. Review.
2011
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| 5 | SPDEF
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| Prostate-derived Ets transcription factor (PDEF) is a potential prognostic marker in patients with prostate cancer.
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| Ghadersohi A, Sharma S, Zhang S, Azrak RG, Wilding GE, Manjili MH, Li F.
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| Prostate 71(11):1178-88. doi: 10.1002/pros.21333. Epub 2011 Jan 12.
2011
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| 6 | SPDEF, lL13
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| Interleukin-13 induces mucin 5AC production involving STAT6/SPDEF in human airway epithelial cells.
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| Yu H, Li Q, Kolosov VP, Perelman JM, Zhou X.
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| Cell Commun Adhes 17(4-6):83-92. Epub 2011 Jan 28.
2010
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| 7 | SPDEF
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| Requirement of the epithelium-specific Ets transcription factor Spdef for mucous gland cell function in the gastric antrum.
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| Horst D, Gu X, Bhasin M, Yang Q, Verzi M, Lin D, Joseph M, Zhang X, Chen W, Li YP, Shivdasani RA, Libermann TA.
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| J Biol Chem 285(45):35047-55. Epub 2010 Aug 26.
2010
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| 8 | SPDEF
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| SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells.
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| Noah TK, Kazanjian A, Whitsett J, Shroyer NF.
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| Exp Cell Res 316(3):452-65. Epub 2009 Sep 26.
2010
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| 9 | SPDEF
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| PDEF is a negative regulator of colon cancer cell growth and migration.
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| Moussa O, Turner DP, Feldman RJ, Sementchenko VI, McCarragher BD, Desouki MM, Fraig M, Watson DK.
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| J Cell Biochem 108(6):1389-98.
2009
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| 10 | SPDEF
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| The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium.
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| Gregorieff A, Stange DE, Kujala P, Begthel H, van den Born M, Korving J, Peters PJ, Clevers H.
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| Gastroenterology 137(4):1333-45.e1-3. Epub 2009 Jun 21.
2009
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| 11 | SPDEF
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| Global gene expression analysis identifies PDEF transcriptional networks regulating cell migration during cancer progression.
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| Turner DP, Findlay VJ, Kirven AD, Moussa O, Watson DK.
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| Mol Biol Cell 19(9):3745-57. Epub 2008 Jun 25.
2008
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| 12 | SPDEF
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| Reduced PDEF expression increases invasion and expression of mesenchymal genes in prostate cancer cells.
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| Gu X, Zerbini LF, Otu HH, Bhasin M, Yang Q, Joseph MG, Grall F, Onatunde T, Correa RG, Libermann TA.
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| Cancer Res 67(9):4219-26.
2007
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| 13 | SPDEF
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| SPDEF regulates goblet cell hyperplasia in the airway epithelium.
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| Park KS, Korfhagen TR, Bruno MD, Kitzmiller JA, Wan H, Wert SE, Khurana Hershey GK, Chen G, Whitsett JA.
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| J Clin Invest 117(4):978-88. Epub 2007 Mar 8.
2007
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| 14 | SPDEF, NKX3-1
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| Structural and functional analysis of domains mediating interaction between NKX-3.1 and PDEF.
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| Chen H, Bieberich CJ.
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| J Cell Biochem 94(1):168-77. 2005
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| 15 | SPDEF
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| Pdef expression in human breast cancer is correlated with invasive potential and altered gene expression.
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| Feldman RJ, Sementchenko VI, Gayed M, Fraig MM, Watson DK.
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| Cancer Res 63(15):4626-31. 2003
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| 16 | SPDEF
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| p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells.
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| Thompson HG, Harris JW, Wold BJ, Lin F, Brody JP.
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| Oncogene 22(15):2322-33. 2003
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| 17 | KLK3, NKX3-1, SPDEF
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| NKX-3.1 interacts with prostate-derived Ets factor and regulates the activity of the PSA promoter.
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| Chen H, Nandi AK, Li X, Bieberich CJ.
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| Cancer Res 62(2):338-40. 2002
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| 18 | SPDEF
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| Prostate-Specific Ets (PSE) factor: a novel marker for detection of metastatic breast cancer in axillary lymph nodes.
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| Mitas M, Mikhitarian K, Hoover L, Lockett MA, Kelley L, Hill A, Gillanders WE, Cole DJ.
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| Br J Cancer 86(6):899-904. 2002
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| 19 | SPDEF
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| PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression.
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| Oettgen P, Finger E, Sun Z, Akbarali Y, Thamrongsak U, Boltax J, Grall F, Dube A, Weiss A, Brown L, Quinn G, Kas K, Endress G, Kunsch C, Libermann TA.
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| J Biol Chem 275(2):1216-25. 2000
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