Citations for
1SOX10, SOX8, SOX9
The SOXE transcription factors-SOX8, SOX9 and SOX10-share a bi-partite transactivation mechanism.
Haseeb A, Lefebvre V.
Nucleic Acids Res 47(13):6917-6931. doi: 10.1093/nar/gkz523. 2019
2SOX8
Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice.
Kimura S, Kobayashi N, Nakamura Y, Kanaya T, Takahashi D, Fujiki R, Mutoh M, Obata Y, Iwanaga T, Nakagawa T, Kato N, Sato S, Kaisho T, Ohno H, Hase K.
J Exp Med 216(4):831-846. doi: 10.1084/jem.20181604. Epub 2019 Mar 15. 2019
3SOX8, ZEB1
SOX8 acts as a prognostic factor and mediator to regulate the progression of triple-negative breast cancer.
Tang H, Chen B, Liu P, Xie X, He R, Zhang L, Huang X, Xiao X, Xie X.
Carcinogenesis arcinogenesis. 2019 Feb 27. pii: bgz034. doi: 10.1093/carcin/bgz034. [Epub ahead of print] 2019
4SOX8
Over-expression of SOX8 predicts poor prognosis in colorectal cancer: A retrospective study.
Wang Y, Yang W, Liu T, Bai G, Liu M, Wang W.
Medicine (Baltimore) 98(27):e16237. doi: 10.1097/MD.0000000000016237. 2019
5SOX10, SOX8
Sox8 and Sox10 jointly maintain myelin gene expression in oligodendrocytes.
Turnescu T, Arter J, Reiprich S, Tamm ER, Waisman A, Wegner M.
Glia 66(2):279-294. doi: 10.1002/glia.23242. Epub 2017 Oct 11. 2018
6SOX8
Selective neuronal expression of the SoxE factor, Sox8, in direct pathway striatal projection neurons of the developing mouse brain.
Merchan-Sala P, Nardini D, Waclaw RR, Campbell K.
J Comp Neurol 525(13):2805-2819. doi: 10.1002/cne.24232. Epub 2017 May 22. 2017
7DMRT1, SOX8, SOX9
Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.
Barrionuevo FJ, Hurtado A, Kim GJ, Real FM, Bakkali M, Kopp JL, Sander M, Scherer G, Burgos M, Jiménez R.
Elife 5. pii: e15635. doi: 10.7554/eLife.15635. 2016
8COL2A1, SOX5, SOX6, SOX8, SOX9
Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells.
Herlofsen SR, Høiby T, Cacchiarelli D, Zhang X, Mikkelsen TS, Brinchmann JE.
Stem Cells 32(6):1629-35. doi: 10.1002/stem.1642. 2014
9SOX8
SOX8 regulates permeability of the blood-testes barrier that affects adult male fertility in the mouse.
Singh AP, Cummings CA, Mishina Y, Archer TK.
Biol Reprod 88(5):133. doi: 10.1095/biolreprod.112.107284. Print 2013 May. 2013
10SOX10, SOX8, SOX9
Sox9 and Sox8 are required for basal lamina integrity of testis cords and for suppression of FOXL2 during embryonic testis development in mice.
Georg I, Barrionuevo F, Wiech T, Scherer G.
Biol Reprod 87(4):99. doi: 10.1095/biolreprod.112.101907. Print 2012 Oct. 2012
11SOX8, SOX9
SOX9 controls epithelial branching by activating RET effector genes during kidney development.
Reginensi A, Clarkson M, Neirijnck Y, Lu B, Ohyama T, Groves AK, Sock E, Wegner M, Costantini F, Chaboissier MC, Schedl A.
Hum Mol Genet 20(6):1143-53. Epub 2011 Jan 6. 2011
12SOX8
Evolutionary conserved sequence elements with embryonic enhancer activity in the vicinity of the mammalian Sox8 gene.
Guth SI, Bösl MR, Sock E, Wegner M.
Int J Biochem Cell Biol 42(3):465-71. Epub 2009 Jul 26.PMID: 19638316 2010
13SOX8
Downstream genes of Sox8 that would affect adult male fertility.
Singh AP, Harada S, Mishina Y.
Sex Dev 3(1):16-25. Epub 2009 Apr 1.PMID: 19339814 2009
14SOX8
Adult-onset degeneration of adipose tissue in mice deficient for the Sox8 transcription factor.
Guth SI, Schmidt K, Hess A, Wegner M.
J Lipid Res 50(7):1269-80. Epub 2009 Mar 12.PMID: 19286648 2009
15SOX8, SOX9
Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8.
Barrionuevo F, Georg I, Scherthan H, Lécureuil C, Guillou F, Wegner M, Scherer G.
Dev Biol 327(2):301-12. Epub 2008 Dec 24.PMID: 19124014 2009
16SOX8
Sox8 is a critical regulator of adult Sertoli cell function and male fertility.
O'Bryan MK, Takada S, Kennedy CL, Scott G, Harada S, Ray MK, Dai Q, Wilhelm D, de Kretser DM, Eddy EM, Koopman P, Mishina Y.
Dev Biol 316(2):359-70. Epub 2008 Feb 13.PMID: 18342849 2008
17SOX8
Sox8 and Sertoli-cell function.
Kennedy CL, Koopman P, Mishina Y, O'Bryan MK.
Ann N Y Acad Sci 1120:104-13. Epub 2007 Sep 28.PMID: 17905940 2007
18SOX10, SOX8
Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence.
Kellerer S, Schreiner S, Stolt CC, Scholz S, Bösl MR, Wegner M.
Development 133(15):2875-86. Epub 2006 Jun 21.PMID: 16790476 2006
19SOX8
Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord.
Stolt CC, Schmitt S, Lommes P, Sock E, Wegner M.
Dev Biol 281(2):309-17.PMID: 15893981 2005
20SOX8
The high mobility group transcription factor Sox8 is a negative regulator of osteoblast differentiation.
Schmidt K, Schinke T, Haberland M, Priemel M, Schilling AF, Mueldner C, Rueger JM, Sock E, Wegner M, Amling M.
J Cell Biol 168(6):899-910. Epub 2005 Mar 7.PMID: 15753123 2005
21SOX8
Origin and possible roles of the Sox8 transcription factor gene during sexual development.
Takada S, Koopman P.
Cytogenet Genome Res 101(3-4):212-8. Review. 2003
22SOX10, SOX8, SOX9
Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8.
Sock E, Schmidt K, Hermanns-Borgmeyer I, Bosl MR, Wegner M.
Mol Cell Biol 21(20):6951-9. 2001
23SOX8
Sox8 gene expression identifies immature glial cells in developing cerebellum and cerebellar tumours.
Cheng YC, Lee CJ, Badge RM, Orme AT, Scotting PJ.
Brain Res Mol Brain Res 92(1-2):193-200. 2001
24SOX8
Cloning and characterisation of the Sry-related transcription factor gene Sox8.
Schepers GE, Bullejos M, Hosking BM, Koopman P.
Nucleic Acids Res 28(6):1473-80. 2000
25ATR16, SOX8
The SOX8 gene is located within 700 kb of the tip of chromosome 16p and is deleted in a patient with ATR-16 syndrome.
Pfeifer D, Poulat F, Holinski-Feder E, Kooy F, Scherer G.
Genomics 63(1):108-16. 2000