| 1 | SOX6
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| Sox6 as a new modulator of renin expression in the kidney.
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| Saleem M, Hodgkinson CP, Xiao L, Gimenez-Bastida JA, Rasmussen ML, Foss J, Payne AJ, Mirotsou M, Gama V, Dzau VJ, Gomez JA.
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| Am J Physiol Renal Physiol. Feb 1;318(2):F285-F297. doi: 10.1152/ajprenal.00095.2019. Epub 2019 Nov 25 2020
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| 2 | SOX6, TOLCAS
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| De Novo SOX6 Variants Cause a Neurodevelopmental Syndrome Associated with ADHD, Craniosynostosis, and Osteochondromas.
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| Tolchin D, Yeager JP, Prasad P, Dorrani N, Russi AS, Martinez-Agosto JA, Haseeb A, Angelozzi M, Santen GWE, Ruivenkamp C, Mercimek-Andrews S, Depienne C, Kuechler A, Mikat B, Ludecke HJ, Bilan F, Le Guyader G, Gilbert-Dussardier B, Keren B, Heide S, Haye D, Van Esch H, Keldermans L, Ortiz D, Lancaster E, Krantz ID, Krock BL, Pechter KB, Arkader A, Medne L, DeChene ET, Calpena E, Melistaccio G, Wilkie AOM, Suri M, Foulds N; Genomics England Research Consortium, Begtrup A, Henderson LB, Forster C, Reed P, McDonald MT, McConkie-Rosell A, Thevenon J, Le Tanno P, Coutton C, Tsai ACH, Stewart S, Maver A, Gorazd R, Pichon O, Nizon M, Cogné B, Isidor B, Martin-Coignard D, Stoeva R, Lefebvre V, Le Caignec C.
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| Am J Hum Genet. Jun 4;106(6):830-845. doi: 10.1016/j.ajhg.2020.04.015. Epub 2020 May 21 2020
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| 3 | SOX5, SOX6, SOX9
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| Roles and regulation of SOX transcription factors in skeletogenesis.
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| Lefebvre V.
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| Curr Top Dev Biol. 133:171-193. doi: 10.1016/bs.ctdb.2019.01.007. Epub 2019 Feb 26 2019
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| 4 | SOX6, TWIST1
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| Identification of Sox6 as a regulator of pancreatic cancer development.
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| Jiang W, Yuan Q, Jiang Y, Huang L, Chen C, Hu G, Wan R, Wang X, Yang L.
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| J Cell Mol Med. Mar;22(3):1864-1872. doi: 10.1111/jcmm.13470. Epub 2018 Jan 25 2018
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| 5 | SOX5, SOX6
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| Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain.
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| Baroti T, Zimmermann Y, Schillinger A, Liu L, Lommes P, Wegner M, Stolt CC.
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| Glia 64(1):122-38. doi: 10.1002/glia.22919. Epub 2015 Sep 8.
2016
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| 6 | CEBPA, MEST, PPARG, SOX6
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| The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis.
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| Leow SC, Poschmann J, Too PG, Yin J, Joseph R, McFarlane C, Dogra S, Shabbir A, Ingham PW, Prabhakar S, Leow MK, Lee YS, Ng KL, Chong YS, Gluckman PD, Stünkel W.
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| Development Mar 15;143(6):950-61. doi: 10.1242/dev.131573. Epub 2016 Feb 18 2016
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| 7 | SOX6
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| Disruption of SOX6 is associated with a rapid-onset dopa-responsive movement disorder, delayed development, and dysmorphic features.
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| Ebrahimi-Fakhari D, Maas B, Haneke C, Niehues T, Hinderhofer K, Assmann BE, Runz H.
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| Pediatr Neurol 52(1):115-8. doi: 10.1016/j.pediatrneurol.2014.08.021. Epub 2014 Sep 17.
2015
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| 8 | RUNX2, SOX6
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| Functional analyses reveal the essential role of SOX6 and RUNX2 in the communication of chondrocyte and osteoblast.
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| Zhang Y, Yang TL, Li X, Guo Y.
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| Osteoporos Int 26(2):553-61. doi: 10.1007/s00198-014-2882-3. Epub 2014 Sep 12.
2015
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| 9 | SOX5, SOX6, SOX9
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| The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis.
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| Liu CF, Lefebvre V.
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| Nucleic Acids Res. Sep 30;43(17):8183-203. doi: 10.1093/nar/gkv688. Epub 2015 Jul 6 2015
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| 10 | OTX2, SOX6
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| Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons.
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| Panman L, Papathanou M, Laguna A, Oosterveen T, Volakakis N, Acampora D, Kurtsdotter I, Yoshitake T, Kehr J, Joodmardi E, Muhr J, Simeone A, Ericson J, Perlmann T.
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| Cell Rep 8(4):1018-25. doi: 10.1016/j.celrep.2014.07.016. Epub 2014 Aug 7.
2014
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| 11 | CDK5, SOX6
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| Regulation of Sox6 by cyclin dependent kinase 5 in brain.
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| Rudrabhatla P, Utreras E, Jaffe H, Kulkarni AB.
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| PLoS One 9(3):e89310. doi: 10.1371/journal.pone.0089310. eCollection 2014.
2014
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| 12 | COL2A1, SOX5, SOX6, SOX8, SOX9
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| Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells.
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| Herlofsen SR, Hřiby T, Cacchiarelli D, Zhang X, Mikkelsen TS, Brinchmann JE.
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| Stem Cells 32(6):1629-35. doi: 10.1002/stem.1642.
2014
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| 13 | SOX6, TRIP12
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| Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells.
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| An CI, Ganio E, Hagiwara N.
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| Skelet Muscle 3(1):11. doi: 10.1186/2044-5040-3-11.
2013
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| 14 | SOX6
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| Decreased expression of SOX6 confers a poor prognosis in hepatocellular carcinoma.
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| Guo X, Yang M, Gu H, Zhao J, Zou L.
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| Cancer Epidemiol 37(5):732-6. doi: 10.1016/j.canep.2013.05.002. Epub 2013 Jun 1.
2013
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| 15 | MAPK14, SOX6, ZAK
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| The protein kinase MLTK regulates chondrogenesis by inducing the transcription factor Sox6.
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| Suzuki T, Kusakabe M, Nakayama K, Nishida E.
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| Development 139(16):2988-98. doi: 10.1242/dev.078675. Epub 2012 Jul 4.
2012
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| 16 | MKX, MYH7, SOX6
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| Characterization of the DNA-binding properties of the Mohawk homeobox transcription factor.
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| Anderson DM, George R, Noyes MB, Rowton M, Liu W, Jiang R, Wolfe SA, Wilson-Rawls J, Rawls A.
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| J Biol Chem 287(42):35351-9. doi: 10.1074/jbc.M112.399386. Epub 2012 Aug 24.
2012
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| 17 | SOX6, STAT3
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| Stat3 is essential for neuronal differentiation through direct transcriptional regulation of the Sox6 gene.
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| Snyder M, Huang XY, Zhang JJ.
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| FEBS Lett 585(1):148-52. Epub 2010 Nov 19.
2011
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| 18 | SOX6
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| A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cells.
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| Cantu' C, Grande V, Alborelli I, Cassinelli L, Cantu' I, Colzani MT, Ierardi R, Ronzoni L, Cappellini MD, Ferrari G, Ottolenghi S, Ronchi A.
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| Nucleic Acids Res 39(2):486-501. Epub 2010 Sep 17.
2011
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| 19 | SHOX, SOX5, SOX6, SOX9
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| SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer.
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| Aza-Carmona M, Shears DJ, Yuste-Checa P, Barca-Tierno V, Hisado-Oliva A, Belinchón A, Benito-Sanz S, Rodríguez JI, Argente J, Campos-Barros A, Scambler PJ, Heath KE.
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| Hum Mol Genet 20(8):1547-59. Epub 2011 Jan 24.
2011
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| 20 | SOCS3, SOX6
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| Sox6 enhances erythroid differentiation in human erythroid progenitors.
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| Cantů C, Ierardi R, Alborelli I, Fugazza C, Cassinelli L, Piconese S, Bosč F, Ottolenghi S, Ferrari G, Ronchi A.
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| Blood 117(13):3669-79. doi: 10.1182/blood-2010-04-282350. Epub 2011 Jan 24.
2011
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| 21 | SOX13, SOX5, SOX6
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| The SoxD transcription factors--Sox5, Sox6, and Sox13--are key cell fate modulators.
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| Lefebvre V.
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| Int J Biochem Cell Biol 42(3):429-32. Epub 2009 Jul 30. Review.PMID: 19647094 2010
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| 22 | BCL11A, SOX6
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| Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.
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| Xu J, Sankaran VG, Ni M, Menne TF, Puram RV, Kim W, Orkin SH.
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| Genes Dev 24(8):783-98.
2010
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| 23 | SOX5, SOX6
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| SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development.
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| Azim E, Jabaudon D, Fame RM, Macklis JD.
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| Nat Neurosci. 12(10):1238-47. 2009
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| 24 | SOX6
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| Identification and characterization of the human SOX6 promoter.
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| Ikeda T, Saito T, Ushita M, Yano F, Kan A, Itaka K, Moro T, Nakamura K, Kawaguchi H, Chung UI.
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| Biochem Biophys Res Commun 357(2):383-90. Epub 2007 Apr 2. 2007
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| 25 | SOX6,STAT3
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| The nuclear localization of SOCS6 requires the N-terminal region and negatively regulates Stat3 protein levels.
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| Hwang MN, Min CH, Kim HS, Lee H, Yoon KA, Park SY, Lee ES, Yoon S.
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| Biochem Biophys Res Commun 360(2):333-8. Epub 2007 Jun 19. 2007
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| 26 | TRPV4, SOX98, SOX6
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| Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation.
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| Muramatsu S, Wakabayashi M, Ohno T, Amano K, Ooishi R, Sugahara T, Shiojiri S, Tashiro K, Suzuki Y, Nishimura R, Kuhara S, Sugano S, Yoneda T, Matsuda A.
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| J Biol Chem 282(44):32158-67. Epub 2007 Sep 5. 2007
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| 27 | SOX6, SOX5, SOX9
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| Balanced translocation in a patient with craniosynostosis disrupts the SOX6 gene and an evolutionarily conserved non-transcribed region.
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| Tagariello A, Heller R, Greven A, Kalscheuer VM, Molter T, Rauch A, Kress W, Winterpacht A.
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| J Med Genet 43(6):534-40. Epub 2005 Oct 28. 2006
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| 28 | SOX6, SUMO2
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| Repression of SOX6 transcriptional activity by SUMO modification.
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| Fern‡ndez-Lloris R, Osses N, Jaffray E, Shen LN, Vaughan OA, Girwood D, Bartrons R, Rosa JL, Hay RT, Ventura F.
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| FEBS Lett 580(5):1215-21. Epub 2006 Jan 20. 2006
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| 29 | SOX5, SOX6
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| SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.
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| Stolt CC, Schlierf A, Lommes P, Hillgärtner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M.
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| Dev Cell. 11(5):697-709. 2006
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| 30 | SOX6
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| Sox6 regulation of cardiac myocyte development.
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| Cohen-Barak O, Yi Z, Hagiwara N, Monzen K, Komuro I, Brilliant MH.
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| Nucleic Acids Res. 31(20):5941-8. 2003
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| 31 | HDAC4, SOX6
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| Differential localization of HDAC4 orchestrates muscle differentiation.
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| Miska EA, Langley E, Wolf D, Karlsson C, Pines J, Kouzarides T.
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| Nucleic Acids Res 29(16):3439-47. 2001
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| 32 | SOX6
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| Cloning, characterization and chromosome mapping of the human SOX6 gene.
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| Cohen-Barak O, Hagiwara N, Arlt MF, Horton JP, Brilliant MH.
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| Gene 265(1-2):157-64. 2001
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| 33 | SOX6
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| SOX6 binds CtBP2 to repress transcription from the Fgf-3 promoter.
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| Murakami A, Ishida S, Thurlow J, Revest JM, Dickson C.
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| Nucleic Acids Res. 29(16):3347-55. 2001
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| 34 | SOX5, SOX6
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| The transcription factors L-Sox5 and Sox6 are essential for cartilage formation.
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| Smits, P., Li, P., Mandel, J., Zhang, Z., Deng, J. M., Behringer, R. R., de Crombrugghe, B., Lefebvre, V.
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| Dev Cell. 1, 277-290 2001
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| 35 | SOX6
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| Characterization of Solt, a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis.
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| Yamashita A, Ito M, Takamatsu N, Shiba T.
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| FEBS Lett. 481(2):147-51. 2000
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| 36 | SOX6
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| Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death.
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| Hagiwara, N., Klewer, S. E., Samson, R. A., Erickson, D. T., Lyon, M. F., Brilliant, M. H.
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| Proc. Nat. Acad. Sci. 97, 4180-4185 2000
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| 37 | SOX5, SOX6, SOX9
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| A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene.
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| Lefebvre V, Li P, de Crombrugghe B.
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| EMBO J 17(19):5718-33. 1998
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