Citations for
1SOX5
SOX5 promotes breast cancer proliferation and invasion by transactivation of EZH2.
Sun C, Ban Y, Wang K, Sun Y, Zhao Z.
Oncol Lett 17(3):2754-2762. doi: 10.3892/ol.2019.9914. Epub 2019 Jan 9. 2019
2SOX5, SOX6, SOX9
Roles and regulation of SOX transcription factors in skeletogenesis.
Lefebvre V.
Curr Top Dev Biol. 133:171-193. doi: 10.1016/bs.ctdb.2019.01.007. Epub 2019 Feb 26 2019
3DPYSL5, SOX5
Transcriptional regulation of CRMP5 controls neurite outgrowth through Sox5.
Naudet N, Moutal A, Vu HN, Chounlamountri N, Watrin C, Cavagna S, Malleval C, Benetollo C, Bardel C, Dronne MA, Honnorat J, Meissirel C, Besançon R.
Cell Mol Life Sci 75(1):67-79. doi: 10.1007/s00018-017-2634-6. Epub 2017 Sep 1. 2018
4SOX5
Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.
Axelsson AS, Mahdi T, Nenonen HA, Singh T, Hänzelmann S, Wendt A, Bagge A, Reinbothe TM, Millstein J, Yang X, Zhang B, Gusmao EG, Shu L, Szabat M, Tang Y, Wang J, Salö S, Eliasson L, Artner I, Fex M, Johnson JD, Wollheim CB, Derry JMJ, Mecham B, Spégel P, Mulder H, Costa IG, Zhang E, Rosengren AH.
Nat Commun 8:15652. doi: 10.1038/ncomms15652. 2017
5SOX5
Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment.
Li A, Hooli B, Mullin K, Tate RE, Bubnys A, Kirchner R, Chapman B, Hofmann O, Hide W, Tanzi RE.
Hum Mol Genet 26(8):1472-1482. doi: 10.1093/hmg/ddx051. 2017
6SOX5, SPAG16
Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5.
Zhang L, Liu Y, Li W, Zhang Q, Li Y, Liu J, Min J, Shuang C, Song S, Zhang Z.
BMC Mol Biol. Jan 31;18(1):2. doi: 10.1186/s12867-017-0082-3 2017
7MITF, SOX5
SOX5 is involved in balanced MITF regulation in human melanoma cells.
Kordaß T, Weber CE, Oswald M, Ast V, Bernhardt M, Novak D, Utikal J, Eichmüller SB, König R.
BMC Med Genomics 9:10. doi: 10.1186/s12920-016-0170-0. 2016
8SOX5, SOX6
Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain.
Baroti T, Zimmermann Y, Schillinger A, Liu L, Lommes P, Wegner M, Stolt CC.
Glia 64(1):122-38. doi: 10.1002/glia.22919. Epub 2015 Sep 8. 2016
9LAMSHF, SOX5
Exome sequencing expands the mechanism of SOX5-associated intellectual disability: A case presentation with review of sox-related disorders.
Nesbitt A, Bhoj EJ, McDonald Gibson K, Yu Z, Denenberg E, Sarmady M, Tischler T, Cao K, Dubbs H, Zackai EH, Santani A.
Am J Med Genet A 167A(11):2548-54. doi: 10.1002/ajmg.a.37221. Epub 2015 Jun 25. Review. 2015
10SOX5
SOX5 promotes epithelial-mesenchymal transition and cell invasion via regulation of Twist1 in hepatocellular carcinoma.
Wang D, Han S, Wang X, Peng R, Li X.
Med Oncol 32(2):461. doi: 10.1007/s12032-014-0461-2. Epub 2015 Jan 9. 2015
11SOX5
Sox5 controls dorsal progenitor and interneuron specification in the spinal cord.
Quiroga AC, Stolt CC, Diez del Corral R, Dimitrov S, Pérez-Alcalá S, Sock E, Barbas JA, Wegner M, Morales AV.
Dev Neurobiol 75(5):522-38. doi: 10.1002/dneu.22240. Epub 2014 Nov 13. 2015
12SOX5, SOX6, SOX9
The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis.
Liu CF, Lefebvre V.
Nucleic Acids Res. Sep 30;43(17):8183-203. doi: 10.1093/nar/gkv688. Epub 2015 Jul 6 2015
13SOX5, TWIST1
Sox5 induces epithelial to mesenchymal transition by transactivation of Twist1.
Pei XH, Lv XQ, Li HX.
Biochem Biophys Res Commun 446(1):322-7. doi: 10.1016/j.bbrc.2014.02.109. Epub 2014 Mar 4. 2014
14MAF, RORC, SOX5, STAT3
Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3.
Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K, Takatori H, Tamachi T, Hirose K, Onodera A, Suzuki J, Ohara O, Yamashita M, Nakayama T, Nakajima H.
J Exp Med 211(9):1857-74. doi: 10.1084/jem.20130791. Epub 2014 Jul 29. 2014
15CATSPER1, SOX5, SOX9
The transcription factors Sox5 and Sox9 regulate Catsper1 gene expression.
Mata-Rocha M, Hernández-Sánchez J, Guarneros G, de la Chesnaye E, Sánchez-Tusié AA, Treviño CL, Felix R, Oviedo N.
FEBS Lett 588(18):3352-60. doi: 10.1016/j.febslet.2014.07.024. Epub 2014 Aug 4. 2014
16COL2A1, SOX5, SOX6, SOX8, SOX9
Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells.
Herlofsen SR, Høiby T, Cacchiarelli D, Zhang X, Mikkelsen TS, Brinchmann JE.
Stem Cells 32(6):1629-35. doi: 10.1002/stem.1642. 2014
17LAMSHF, SOX5
Deletion 12p12 involving SOX5 in two children with developmental delay and dysmorphic features.
Lee RW, Bodurtha J, Cohen J, Fatemi A, Batista D.
Pediatr Neurol 48(4):317-20. doi: 10.1016/j.pediatrneurol.2012.12.013. 2013
18DEL12P12, SOX5
Haploinsufficiency of SOX5 at 12p12.1 is associated with developmental delays with prominent language delay, behavior problems, and mild dysmorphic features.
Lamb AN, Rosenfeld JA, Neill NJ, Talkowski ME, Blumenthal I, Girirajan S, Keelean-Fuller D, Fan Z, Pouncey J, Stevens C, Mackay-Loder L, Terespolsky D, Bader PI, Rosenbaum K, Vallee SE, Moeschler JB, Ladda R, Sell S, Martin J, Ryan S, Jones MC, Moran R, Shealy A, Madan-Khetarpal S, McConnell J, Surti U, Delahaye A, Heron-Longe B, Pipiras E, Benzacken B, Passemard S, Verloes A, Isidor B, Le Caignec C, Glew GM, Opheim KE, Descartes M, Eichler EE, Morton CC, Gusella JF, Schultz RA, Ballif BC, Shaffer LG.
Hum Mutat 33(4):728-40. doi: 10.1002/humu.22037. 2012
19LAMSHF, SOX5
Haploinsufficiency of SOX5 at 12p12.1 is associated with developmental delays with prominent language delay, behavior problems, and mild dysmorphic features.
Lamb AN, Rosenfeld JA, Neill NJ, Talkowski ME, Blumenthal I, Girirajan S, Keelean-Fuller D, Fan Z, Pouncey J, Stevens C, Mackay-Loder L, Terespolsky D, Bader PI, Rosenbaum K, Vallee SE, Moeschler JB, Ladda R, Sell S, Martin J, Ryan S, Jones MC, Moran R, Shealy A, Madan-Khetarpal S, McConnell J, Surti U, Delahaye A, Heron-Longe B, Pipiras E, Benzacken B, Passemard S, Verloes A, Isidor B, Le Caignec C, Glew GM, Opheim KE, Descartes M, Eichler EE, Morton CC, Gusella JF, Schultz RA, Ballif BC, Shaffer LG.
Hum Mutat 33(4):728-40. doi: 10.1002/humu.22037. 2012
20SHOX, SOX5, SOX6, SOX9
SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer.
Aza-Carmona M, Shears DJ, Yuste-Checa P, Barca-Tierno V, Hisado-Oliva A, Belinchón A, Benito-Sanz S, Rodríguez JI, Argente J, Campos-Barros A, Scambler PJ, Heath KE.
Hum Mol Genet 20(8):1547-59. Epub 2011 Jan 24. 2011
21SOX13, SOX5, SOX6
The SoxD transcription factors--Sox5, Sox6, and Sox13--are key cell fate modulators.
Lefebvre V.
Int J Biochem Cell Biol 42(3):429-32. Epub 2009 Jul 30. Review.PMID: 19647094 2010
22AXIN2, SOX5
SOX5 controls cell cycle progression in neural progenitors by interfering with the WNT-beta-catenin pathway.
Martinez-Morales PL, Quiroga AC, Barbas JA, Morales AV.
EMBO Rep 11(6):466-72. Epub 2010 May 7. 2010
23SOX5, SOX6
SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development.
Azim E, Jabaudon D, Fame RM, Macklis JD.
Nat Neurosci. 12(10):1238-47. 2009
24SOX5
SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons.
Kwan KY, Lam MM, Krsnik Z, Kawasawa YI, Lefebvre V, Sestan N.
Proc Natl Acad Sci U S A 105(41):16021-6. Epub 2008 Oct 7. 2008
25SOX5
SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons.
Kwan KY, Lam MM, Krsnik Z, Kawasawa YI, Lefebvre V, Sestan N.
Proc Natl Acad Sci U S A. 14;105(41):16021-6. 2008
26P2RY8, SOX5
Upregulation of the SOX5 by promoter swapping with the P2RY8 gene in primary splenic follicular lymphoma.
Storlazzi CT, Albano F, Lo Cunsolo C, Doglioni C, Guastadisegni MC, Impera L, Lonoce A, Funes S, Macrì E, Iuzzolino P, Panagopoulos I, Specchia G, Rocchi M.
Leukemia 21(10):2221-5. Epub 2007 Jun 7. No abstract available. PMID: 17554380 2007
27SOX6, SOX5, SOX9
Balanced translocation in a patient with craniosynostosis disrupts the SOX6 gene and an evolutionarily conserved non-transcribed region.
Tagariello A, Heller R, Greven A, Kalscheuer VM, Molter T, Rauch A, Kress W, Winterpacht A.
J Med Genet 43(6):534-40. Epub 2005 Oct 28. 2006
28SOX5, SOX6
SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.
Stolt CC, Schlierf A, Lommes P, Hillgärtner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M.
Dev Cell. 11(5):697-709. 2006
29DAD1L, ETNK1, SOX5
Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DAD-R, correlates with reduced levels of apoptosis and earlier clinical manifestation.
Zafarana G, Gillis AJ, van Gurp RJ, Olsson PG, Elstrodt F, Stoop H, Millan JL, Oosterhuis JW, Looijenga LH.
Cancer Res 62(6):1822-31. 2002
30SOX5
Identification and characterization of the human long form of Sox5 (L-SOX5) gene.
Ikeda T, Zhang J, Chano T, Mabuchi A, Fukuda A, Kawaguchi H, Nakamura K, Ikegawa S.
Gene 298(1):59-68. 2002
31SOX5, SOX6
The transcription factors L-Sox5 and Sox6 are essential for cartilage formation.
Smits, P., Li, P., Mandel, J., Zhang, Z., Deng, J. M., Behringer, R. R., de Crombrugghe, B., Lefebvre, V.
Dev Cell. 1, 277-290 2001
32SOX1, SOX10, SOX11, SOX13, SOX14, SOX2, SOX15, SOX21, SOX12, SOX3, SOX30, SOX4, SOX5, SOX9, SRY
Members of the SRY family regulate the human LINE retrotransposons.
Tchenio T, Casella JF, Heidmann T.
Nucleic Acids Res 28(2):411-5 2000
33SOX1, SOX10, SOX11, SOX14, SOX2, SOX15, SOX12, SOX2L, SOX3, SOX4, SOX5, SOX5P, SOX9
From head to toes: the multiple facets of Sox proteins.
Wegner M.
Nucleic Acids Res 27(6):1409-1420. 1999
34SOX5, SOX6, SOX9
A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene.
Lefebvre V, Li P, de Crombrugghe B.
EMBO J 17(19):5718-33. 1998
35SOX5, SOX5P
Cloning and characterization of SOX5, a new member of the human SOX gene family.
Wunderle VM, et al.
Genomics 36 : 354-358. 1996