1 | SOX5
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| SOX5 promotes breast cancer proliferation and invasion by transactivation of EZH2.
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| Sun C, Ban Y, Wang K, Sun Y, Zhao Z.
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| Oncol Lett 17(3):2754-2762. doi: 10.3892/ol.2019.9914. Epub 2019 Jan 9.
2019
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2 | SOX5, SOX6, SOX9
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| Roles and regulation of SOX transcription factors in skeletogenesis.
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| Lefebvre V.
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| Curr Top Dev Biol. 133:171-193. doi: 10.1016/bs.ctdb.2019.01.007. Epub 2019 Feb 26 2019
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3 | DPYSL5, SOX5
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| Transcriptional regulation of CRMP5 controls neurite outgrowth through Sox5.
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| Naudet N, Moutal A, Vu HN, Chounlamountri N, Watrin C, Cavagna S, Malleval C, Benetollo C, Bardel C, Dronne MA, Honnorat J, Meissirel C, Besançon R.
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| Cell Mol Life Sci 75(1):67-79. doi: 10.1007/s00018-017-2634-6. Epub 2017 Sep 1.
2018
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4 | SOX5
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| Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.
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| Axelsson AS, Mahdi T, Nenonen HA, Singh T, Hänzelmann S, Wendt A, Bagge A, Reinbothe TM, Millstein J, Yang X, Zhang B, Gusmao EG, Shu L, Szabat M, Tang Y, Wang J, Salö S, Eliasson L, Artner I, Fex M, Johnson JD, Wollheim CB, Derry JMJ, Mecham B, Spégel P, Mulder H, Costa IG, Zhang E, Rosengren AH.
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| Nat Commun 8:15652. doi: 10.1038/ncomms15652.
2017
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5 | SOX5
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| Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment.
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| Li A, Hooli B, Mullin K, Tate RE, Bubnys A, Kirchner R, Chapman B, Hofmann O, Hide W, Tanzi RE.
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| Hum Mol Genet 26(8):1472-1482. doi: 10.1093/hmg/ddx051.
2017
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6 | SOX5, SPAG16
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| Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5.
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| Zhang L, Liu Y, Li W, Zhang Q, Li Y, Liu J, Min J, Shuang C, Song S, Zhang Z.
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| BMC Mol Biol. Jan 31;18(1):2. doi: 10.1186/s12867-017-0082-3 2017
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7 | MITF, SOX5
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| SOX5 is involved in balanced MITF regulation in human melanoma cells.
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| Kordaß T, Weber CE, Oswald M, Ast V, Bernhardt M, Novak D, Utikal J, Eichmüller SB, König R.
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| BMC Med Genomics 9:10. doi: 10.1186/s12920-016-0170-0.
2016
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8 | SOX5, SOX6
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| Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain.
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| Baroti T, Zimmermann Y, Schillinger A, Liu L, Lommes P, Wegner M, Stolt CC.
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| Glia 64(1):122-38. doi: 10.1002/glia.22919. Epub 2015 Sep 8.
2016
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9 | LAMSHF, SOX5
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| Exome sequencing expands the mechanism of SOX5-associated intellectual disability: A case presentation with review of sox-related disorders.
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| Nesbitt A, Bhoj EJ, McDonald Gibson K, Yu Z, Denenberg E, Sarmady M, Tischler T, Cao K, Dubbs H, Zackai EH, Santani A.
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| Am J Med Genet A 167A(11):2548-54. doi: 10.1002/ajmg.a.37221. Epub 2015 Jun 25. Review.
2015
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10 | SOX5
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| SOX5 promotes epithelial-mesenchymal transition and cell invasion via regulation of Twist1 in hepatocellular carcinoma.
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| Wang D, Han S, Wang X, Peng R, Li X.
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| Med Oncol 32(2):461. doi: 10.1007/s12032-014-0461-2. Epub 2015 Jan 9.
2015
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11 | SOX5
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| Sox5 controls dorsal progenitor and interneuron specification in the spinal cord.
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| Quiroga AC, Stolt CC, Diez del Corral R, Dimitrov S, Pérez-Alcalá S, Sock E, Barbas JA, Wegner M, Morales AV.
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| Dev Neurobiol 75(5):522-38. doi: 10.1002/dneu.22240. Epub 2014 Nov 13.
2015
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12 | SOX5, SOX6, SOX9
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| The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis.
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| Liu CF, Lefebvre V.
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| Nucleic Acids Res. Sep 30;43(17):8183-203. doi: 10.1093/nar/gkv688. Epub 2015 Jul 6 2015
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13 | SOX5, TWIST1
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| Sox5 induces epithelial to mesenchymal transition by transactivation of Twist1.
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| Pei XH, Lv XQ, Li HX.
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| Biochem Biophys Res Commun 446(1):322-7. doi: 10.1016/j.bbrc.2014.02.109. Epub 2014 Mar 4.
2014
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14 | MAF, RORC, SOX5, STAT3
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| Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3.
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| Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K, Takatori H, Tamachi T, Hirose K, Onodera A, Suzuki J, Ohara O, Yamashita M, Nakayama T, Nakajima H.
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| J Exp Med 211(9):1857-74. doi: 10.1084/jem.20130791. Epub 2014 Jul 29.
2014
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15 | CATSPER1, SOX5, SOX9
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| The transcription factors Sox5 and Sox9 regulate Catsper1 gene expression.
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| Mata-Rocha M, Hernández-Sánchez J, Guarneros G, de la Chesnaye E, Sánchez-Tusié AA, Treviño CL, Felix R, Oviedo N.
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| FEBS Lett 588(18):3352-60. doi: 10.1016/j.febslet.2014.07.024. Epub 2014 Aug 4.
2014
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16 | COL2A1, SOX5, SOX6, SOX8, SOX9
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| Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells.
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| Herlofsen SR, Høiby T, Cacchiarelli D, Zhang X, Mikkelsen TS, Brinchmann JE.
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| Stem Cells 32(6):1629-35. doi: 10.1002/stem.1642.
2014
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17 | LAMSHF, SOX5
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| Deletion 12p12 involving SOX5 in two children with developmental delay and dysmorphic features.
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| Lee RW, Bodurtha J, Cohen J, Fatemi A, Batista D.
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| Pediatr Neurol 48(4):317-20. doi: 10.1016/j.pediatrneurol.2012.12.013.
2013
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18 | DEL12P12, SOX5
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| Haploinsufficiency of SOX5 at 12p12.1 is associated with developmental delays with prominent language delay, behavior problems, and mild dysmorphic features.
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| Lamb AN, Rosenfeld JA, Neill NJ, Talkowski ME, Blumenthal I, Girirajan S, Keelean-Fuller D, Fan Z, Pouncey J, Stevens C, Mackay-Loder L, Terespolsky D, Bader PI, Rosenbaum K, Vallee SE, Moeschler JB, Ladda R, Sell S, Martin J, Ryan S, Jones MC, Moran R, Shealy A, Madan-Khetarpal S, McConnell J, Surti U, Delahaye A, Heron-Longe B, Pipiras E, Benzacken B, Passemard S, Verloes A, Isidor B, Le Caignec C, Glew GM, Opheim KE, Descartes M, Eichler EE, Morton CC, Gusella JF, Schultz RA, Ballif BC, Shaffer LG.
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| Hum Mutat 33(4):728-40. doi: 10.1002/humu.22037.
2012
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19 | LAMSHF, SOX5
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| Haploinsufficiency of SOX5 at 12p12.1 is associated with developmental delays with prominent language delay, behavior problems, and mild dysmorphic features.
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| Lamb AN, Rosenfeld JA, Neill NJ, Talkowski ME, Blumenthal I, Girirajan S, Keelean-Fuller D, Fan Z, Pouncey J, Stevens C, Mackay-Loder L, Terespolsky D, Bader PI, Rosenbaum K, Vallee SE, Moeschler JB, Ladda R, Sell S, Martin J, Ryan S, Jones MC, Moran R, Shealy A, Madan-Khetarpal S, McConnell J, Surti U, Delahaye A, Heron-Longe B, Pipiras E, Benzacken B, Passemard S, Verloes A, Isidor B, Le Caignec C, Glew GM, Opheim KE, Descartes M, Eichler EE, Morton CC, Gusella JF, Schultz RA, Ballif BC, Shaffer LG.
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| Hum Mutat 33(4):728-40. doi: 10.1002/humu.22037.
2012
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20 | SHOX, SOX5, SOX6, SOX9
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| SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer.
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| Aza-Carmona M, Shears DJ, Yuste-Checa P, Barca-Tierno V, Hisado-Oliva A, Belinchón A, Benito-Sanz S, Rodríguez JI, Argente J, Campos-Barros A, Scambler PJ, Heath KE.
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| Hum Mol Genet 20(8):1547-59. Epub 2011 Jan 24.
2011
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21 | SOX13, SOX5, SOX6
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| The SoxD transcription factors--Sox5, Sox6, and Sox13--are key cell fate modulators.
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| Lefebvre V.
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| Int J Biochem Cell Biol 42(3):429-32. Epub 2009 Jul 30. Review.PMID: 19647094 2010
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22 | AXIN2, SOX5
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| SOX5 controls cell cycle progression in neural progenitors by interfering with the WNT-beta-catenin pathway.
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| Martinez-Morales PL, Quiroga AC, Barbas JA, Morales AV.
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| EMBO Rep 11(6):466-72. Epub 2010 May 7.
2010
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23 | SOX5, SOX6
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| SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development.
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| Azim E, Jabaudon D, Fame RM, Macklis JD.
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| Nat Neurosci. 12(10):1238-47. 2009
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24 | SOX5
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| SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons.
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| Kwan KY, Lam MM, Krsnik Z, Kawasawa YI, Lefebvre V, Sestan N.
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| Proc Natl Acad Sci U S A 105(41):16021-6. Epub 2008 Oct 7.
2008
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25 | SOX5
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| SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons.
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| Kwan KY, Lam MM, Krsnik Z, Kawasawa YI, Lefebvre V, Sestan N.
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| Proc Natl Acad Sci U S A. 14;105(41):16021-6. 2008
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26 | P2RY8, SOX5
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| Upregulation of the SOX5 by promoter swapping with the P2RY8 gene in primary splenic follicular lymphoma.
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| Storlazzi CT, Albano F, Lo Cunsolo C, Doglioni C, Guastadisegni MC, Impera L, Lonoce A, Funes S, Macrì E, Iuzzolino P, Panagopoulos I, Specchia G, Rocchi M.
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| Leukemia 21(10):2221-5. Epub 2007 Jun 7. No abstract available. PMID: 17554380 2007
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27 | SOX6, SOX5, SOX9
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| Balanced translocation in a patient with craniosynostosis disrupts the SOX6 gene and an evolutionarily conserved non-transcribed region.
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| Tagariello A, Heller R, Greven A, Kalscheuer VM, Molter T, Rauch A, Kress W, Winterpacht A.
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| J Med Genet 43(6):534-40. Epub 2005 Oct 28. 2006
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28 | SOX5, SOX6
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| SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.
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| Stolt CC, Schlierf A, Lommes P, Hillgärtner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M.
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| Dev Cell. 11(5):697-709. 2006
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29 | DAD1L, ETNK1, SOX5
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| Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DAD-R, correlates with reduced levels of apoptosis and earlier clinical manifestation.
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| Zafarana G, Gillis AJ, van Gurp RJ, Olsson PG, Elstrodt F, Stoop H, Millan JL, Oosterhuis JW, Looijenga LH.
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| Cancer Res 62(6):1822-31. 2002
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30 | SOX5
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| Identification and characterization of the human long form of Sox5 (L-SOX5) gene.
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| Ikeda T, Zhang J, Chano T, Mabuchi A, Fukuda A, Kawaguchi H, Nakamura K, Ikegawa S.
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| Gene 298(1):59-68. 2002
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31 | SOX5, SOX6
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| The transcription factors L-Sox5 and Sox6 are essential for cartilage formation.
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| Smits, P., Li, P., Mandel, J., Zhang, Z., Deng, J. M., Behringer, R. R., de Crombrugghe, B., Lefebvre, V.
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| Dev Cell. 1, 277-290 2001
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32 | SOX1, SOX10, SOX11, SOX13, SOX14, SOX2, SOX15, SOX21, SOX12, SOX3, SOX30, SOX4, SOX5, SOX9, SRY
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| Members of the SRY family regulate the human LINE retrotransposons.
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| Tchenio T, Casella JF, Heidmann T.
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| Nucleic Acids Res 28(2):411-5 2000
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33 | SOX1, SOX10, SOX11, SOX14, SOX2, SOX15, SOX12, SOX2L, SOX3, SOX4, SOX5, SOX5P, SOX9
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| From head to toes: the multiple facets of Sox proteins.
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| Wegner M.
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| Nucleic Acids Res 27(6):1409-1420. 1999
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34 | SOX5, SOX6, SOX9
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| A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene.
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| Lefebvre V, Li P, de Crombrugghe B.
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| EMBO J 17(19):5718-33. 1998
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35 | SOX5, SOX5P
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| Cloning and characterization of SOX5, a new member of the human SOX gene family.
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| Wunderle VM, et al.
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| Genomics 36 : 354-358. 1996
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