| 1 | NANOG, SOX2, ZBTB38
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| Heterozygous loss of Zbtb38 leads to early embryonic lethality via the suppression of Nanog and Sox2 expression
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| Nishio M, Matsuura T, Hibi S, Ohta S, Oka C, Sasai N, Ishida Y, Matsuda E.
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| Cell Prolif. Apr;55(4):e13215. doi: 10.1111/cpr.13215. Epub 2022 Mar 17 2022
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| 2 | SLC7A11, SOX2
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| Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11
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| Wang X, Chen Y, Wang X, Tian H, Wang Y, Jin J, Shan Z, Liu Y, Cai Z, Tong X, Luan Y, Tan X, Luan B, Ge X, Ji H, Jiang X, Wang P.
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| Cancer Res. Oct 15;81(20):5217-5229. doi: 10.1158/0008-5472.CAN-21-0567. Epub 2021 Aug 12. 2021
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| 3 | AKT1, FSCN1, HBEGF, SOX2
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| SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGF
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| Xiao W, Zheng S, Xie X, Li X, Zhang L, Yang A, Wang J, Tang H, Xie X.
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| Mol Ther Oncolytics. Mar 13;17:118-129. doi: 10.1016/j.omto.2020.03.001. 2020
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| 4 | MELK, SOX2
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| MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
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| Ren L, Deng B, Saloura V, Park JH, Nakamura Y.
|
| Oncol Rep 41(4):2540-2548. doi: 10.3892/or.2019.6988. Epub 2019 Jan 30.
2019
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| 5 | SOX1, SOX2
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| Expression of a SOX1 overlapping transcript in neural differentiation and cancer models
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| Ahmad A, Strohbuecker S, Tufarelli C, Sottile V.
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| Cell Mol Life Sci. Nov;74(22):4245-4258. doi: 10.1007/s00018-017-2580-3. Epub 2017 Jul 3. 2017
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| 6 | SOX2, SOX3
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| Functional Equivalence of the SOX2 and SOX3 Transcription Factors in the Developing Mouse Brain and Testes.
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| Adikusuma F, Pederick D, McAninch D, Hughes J, Thomas P.
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| Genetics. Jul;206(3):1495-1503. doi: 10.1534/genetics.117.202549. Epub 2017 May 17. 2017
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| 7 | LEF1, PITX2, SOX2
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| Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal.
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| Sun Z, Yu W, Sanz Navarro M, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, Michon F, Klein OD, Chai Y, Dupuy A, Engelhardt JF, Chen Z, Amendt BA.
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| Development 143(22):4115-4126.
2016
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| 8 | NACC1, POU5F1, SOX2, TCF3
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| Nac1 Coordinates a Sub-network of Pluripotency Factors to Regulate Embryonic Stem Cell Differentiation.
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| Malleshaiah M, Padi M, Rué P, Quackenbush J, Martinez-Arias A, Gunawardena J.
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| Cell Rep 14(5):1181-94. doi: 10.1016/j.celrep.2015.12.101.
2016
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| 9 | DDX17, SOX2
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| DDX17 (P72), a Sox2 binding partner, promotes stem-like features conferred by Sox2 in a small cell population in estrogen receptor-positive breast cancer.
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| Alqahtani H, Gopal K, Gupta N, Jung K, Alshareef A, Ye X, Wu F, Li L, Lai R.
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| Cell Signal 28(2):42-50. doi: 10.1016/j.cellsig.2015.11.004. Epub 2015 Nov 10.
2016
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| 10 | NOS1, SOX2
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| nNOS Translocates into the Nucleus and Interacts with Sox2 to Protect Neurons Against Early Excitotoxicity via Promotion of Shh Transcription.
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| Zhang D, Wang H, Liu H, Tao T, Wang N, Shen A.
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| Mol Neurobiol 53(9):6444-6458. doi: 10.1007/s12035-015-9545-z. Epub 2015 Nov 25.
2016
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| 11 | LIN28A, NANOG, PCGF6, POU5F1, SOX2
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| Polycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity
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| Yang CS, Chang KY, Dang J, Rana TM.
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| Sci Rep. Jun 1;6:26899. doi: 10.1038/srep26899. 2016
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| 12 | ACTL6A, NANOG, SOX2
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| Actl6a protects embryonic stem cells from differentiating into primitive endoderm.
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| Lu W, Fang L, Ouyang B, Zhang X, Zhan S, Feng X, Bai Y, Han X, Kim H, He Q, Wan M, Shi FT, Feng XH, Liu D, Huang J, Songyang Z.
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| Stem Cells 33(6):1782-93. doi: 10.1002/stem.2000.
2015
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| 13 | MSX2, NODAL, SOX2
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| MSX2 mediates entry of human pluripotent stem cells into mesendoderm by simultaneously suppressing SOX2 and activating NODAL signaling.
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| Wu Q, Zhang L, Su P, Lei X, Liu X, Wang H, Lu L, Bai Y, Xiong T, Li D, Zhu Z, Duan E, Jiang E, Feng S, Han M, Xu Y, Wang F, Zhou J.
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| Cell Res 25(12):1314-32. doi: 10.1038/cr.2015.118.
2015
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| 14 | IL6, SOX2
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| Interleukin-6 induces the lineage commitment of bone marrow-derived mesenchymal multipotent cells through down-regulation of Sox2 by osteogenic transcription factors.
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| Yoon DS, Kim YH, Lee S, Lee KM, Park KH, Jang Y, Lee JW.
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| FASEB J 28(7):3273-86. doi: 10.1096/fj.13-248567. Epub 2014 Apr 9.
2014
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| 15 | SOX2, SOX3, SOXB1
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| Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes
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| Hoffmann SA, Hos D, Küspert M, Lang RA, Lovell-Badge R, Wegner M, Reiprich S.
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| Development. Jan;141(1):39-50. doi: 10.1242/dev.098418. Epub 2013 Nov 20. 2014
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| 16 | POU5F1, SOX17, SOX2
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| Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.
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| Aksoy I, Jauch R, Chen J, Dyla M, Divakar U, Bogu GK, Teo R, Leng Ng CK, Herath W, Lili S, Hutchins AP, Robson P, Kolatkar PR, Stanton LW.
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| EMBO J 32(7):938-53. doi: 10.1038/emboj.2013.31. Epub 2013 Mar 8.
2013
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| 17 | CDX2, SOX2
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| Disturbed balance between SOX2 and CDX2 in human vitelline duct anomalies and intestinal duplications.
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| Raghoebir L, Biermann K, Buscop-van Kempen M, Wijnen RM, Tibboel D, Smits R, Rottier RJ.
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| Virchows Arch 462(5):515-22. doi: 10.1007/s00428-013-1405-5. Epub 2013 Apr 9.
2013
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| 18 | ANOP3, SOX2
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| SOX2 anophthalmia syndrome in adulthood - a neurodegenerative picture?
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| Ragge NK, Quaghebeur G, Stewart H.
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| Clin Genet 83(5):482-4. doi: 10.1111/j.1399-0004.2012.01922.x. Epub 2012 Jul 27. No abstract available.
2013
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| 19 | FN1, SOX2
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| SOX2 targets fibronectin 1 to promote cell migration and invasion in ovarian cancer: new molecular leads for therapeutic intervention.
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| Lou X, Han X, Jin C, Tian W, Yu W, Ding D, Cheng L, Huang B, Jiang H, Lin B.
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| OMICS 17(10):510-8. doi: 10.1089/omi.2013.0058. Epub 2013 Jul 29.
2013
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| 20 | NANOG, SOX2
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| A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.
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| Gagliardi A, Mullin NP, Ying Tan Z, Colby D, Kousa AI, Halbritter F, Weiss JT, Felker A, Bezstarosti K, Favaro R, Demmers J, Nicolis SK, Tomlinson SR, Poot RA, Chambers I.
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| EMBO J 32(16):2231-47. doi: 10.1038/emboj.2013.161. Epub 2013 Jul 26.
2013
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| 21 | PQBP1, SOX2
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| Sox2 transcriptionally regulates PQBP1, an intellectual disability-microcephaly causative gene, in neural stem progenitor cells.
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| Li C, Ito H, Fujita K, Shiwaku H, Qi Y, Tagawa K, Tamura T, Okazawa H.
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| PLoS One 8(7):e68627. doi: 10.1371/journal.pone.0068627. Print 2013.
2013
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| 22 | SIX3, SOX2
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| Genomic code for Sox2 binding uncovers its regulatory role in Six3 activation in the forebrain.
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| Lee B, Song H, Rizzoti K, Son Y, Yoon J, Baek K, Jeong Y.
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| Dev Biol 381(2):491-501. doi: 10.1016/j.ydbio.2013.06.016. Epub 2013 Jun 19.
2013
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| 23 | BIRC5, SOX2
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| Sox2 protects neural stem cells from apoptosis via up-regulating survivin expression.
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| Feng R, Zhou S, Liu Y, Song D, Luan Z, Dai X, Li Y, Tang N, Wen J, Li L.
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| Biochem J 450(3):459-68. doi: 10.1042/BJ20120924.
2013
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| 24 | NANOG, OCT4, SOX2
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| Distinct lineage specification roles for NANOG, OCT4, and SOX2 in human embryonic stem cells.
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| Wang Z, Oron E, Nelson B, Razis S, Ivanova N.
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| Cell Stem Cell 10(4):440-54. doi: 10.1016/j.stem.2012.02.016.
2012
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| 25 | PARP1, SOX2
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| SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency.
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| Lai YS, Chang CW, Pawlik KM, Zhou D, Renfrow MB, Townes TM.
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| Proc Natl Acad Sci U S A 109(10):3772-7. doi: 10.1073/pnas.1108595109. Epub 2012 Feb 23.
2012
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| 26 | NTRK3, SOX2
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| Transcriptional regulation of TRKC by SOX2 in human embryonic stem cells.
|
| Fong H, Wong RC, Donovan PJ.
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| Stem Cell Res 8(2):206-14. doi: 10.1016/j.scr.2011.10.003. Epub 2011 Oct 26.
2012
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| 27 | FGF8, OTX2, SOX2
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| Otx2 is involved in the regional specification of the developing retinal pigment epithelium by preventing the expression of sox2 and fgf8, factors that induce neural retina differentiation.
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| Nishihara D, Yajima I, Tabata H, Nakai M, Tsukiji N, Katahira T, Takeda K, Shibahara S, Nakamura H, Yamamoto H.
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| PLoS One 7(11):e48879. doi: 10.1371/journal.pone.0048879. Epub 2012 Nov 8.
2012
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| 28 | SOX2
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| Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas.
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| Basu-Roy U, Seo E, Ramanathapuram L, Rapp TB, Perry JA, Orkin SH, Mansukhani A, Basilico C.
|
| Oncogene 31(18):2270-82. doi: 10.1038/onc.2011.405. Epub 2011 Sep 19.
2012
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| 29 | ASXL1, SOX2
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| Positive regulation of additional sex comb-like 1 gene expression by the pluripotency factor SOX2.
|
| Kang M, Lee SW, Kim EJ, Um SJ.
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| Biochem Biophys Res Commun 421(3):621-6. doi: 10.1016/j.bbrc.2012.04.072.
2012
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| 30 | SOX2
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| Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer.
|
| Rudin CM, Durinck S, Stawiski EW, Poirier JT, Modrusan Z, Shames DS, Bergbower EA, Guan Y, Shin J, Guillory J, Rivers CS, Foo CK, Bhatt D, Stinson J, Gnad F, Haverty PM, Gentleman R, Chaudhuri S, Janakiraman V, Jaiswal BS, Parikh C, Yuan W, Zhang Z, Koeppen H, Wu TD, Stern HM, Yauch RL, Huffman KE, Paskulin DD, Illei PB, Varella-Garcia M, Gazdar AF, de Sauvage FJ, Bourgon R, Minna JD, Brock MV, Seshagiri S.
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| Nat Genet 44(10):1111-6. doi: 10.1038/ng.2405. Epub 2012 Sep 2.
2012
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| 31 | ANOP3, SOX2
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| Isolated hypogonadotropic hypogonadism with SOX2 mutation and anophthalmia/microphthalmia in offspring.
|
| Stark Z, Storen R, Bennetts B, Savarirayan R, Jamieson RV.
|
| Eur J Hum Genet 19(7):753-6. doi: 10.1038/ejhg.2011.11. Epub 2011 Feb 16.
2011
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| 32 | SOX2
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| SOX2 is required for adult human muller stem cell survival and maintenance of progenicity in vitro.
|
| Bhatia B, Singhal S, Tadman DN, Khaw PT, Limb GA.
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| Invest Ophthalmol Vis Sci. 52(1):136-45. 2011
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| 33 | SOX2
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| The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates.
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| Iwafuchi-Doi M, Yoshida Y, Onichtchouk D, Leichsenring M, Driever W, Takemoto T, Uchikawa M, Kamachi Y, Kondoh H.
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| Dev Biol 352(2):354-66. Epub 2010 Dec 23.
2011
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| 34 | SOX2
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| SOX2 expression levels distinguish between neural progenitor populations of the developing dorsal telencephalon.
|
| Hutton SR, Pevny LH.
|
| Dev Biol 352(1):40-7. Epub 2011 Jan 21.
2011
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| 35 | MET, SOX2
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| Expression of MET and SOX2 genes in non-small cell lung carcinoma with EGFR mutation.
|
| Cai YR, Zhang HQ, Qu Y, Mu J, Zhao D, Zhou LJ, Yan H, Ye JW, Liu Y.
|
| Oncol Rep 26(4):877-85. doi: 10.3892/or.2011.1349. Epub 2011 Jun 15.
2011
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| 36 | CHD7, SOX2
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| Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.
|
| Engelen E, Akinci U, Bryne JC, Hou J, Gontan C, Moen M, Szumska D, Kockx C, van Ijcken W, Dekkers DH, Demmers J, Rijkers EJ, Bhattacharya S, Philipsen S, Pevny LH, Grosveld FG, Rottier RJ, Lenhard B, Poot RA.
|
| Nat Genet 43(6):607-11. Epub 2011 May 1.
2011
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| 37 | CHD7, SOX2
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| SOX2 and CHD7 cooperatively regulate human disease genes.
|
| Puc J, Rosenfeld MG.
|
| Nat Genet 43(6):505-6. No abstract available.
2011
|
| 38 | NANOG, POU5F1, SOX2
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| A DNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells.
|
| Fong YW, Inouye C, Yamaguchi T, Cattoglio C, Grubisic I, Tjian R.
|
| Cell 147(1):120-31.
2011
|
| 39 | BMI1, SOX2
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| Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.
|
| Seo E, Basu-Roy U, Zavadil J, Basilico C, Mansukhani A.
|
| Mol Cell Biol 31(22):4593-608. doi: 10.1128/MCB.05798-11. Epub 2011 Sep 19.
2011
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| 40 | SOX2
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| SOX2 modulates alternative splicing in transitional cell carcinoma.
|
| Tung CL, Hou PH, Kao YL, Huang YW, Shen CC, Cheng YH, Wu SF, Lee MS, Li C.
|
| Biochem Biophys Res Commun 393(3):420-5. Epub 2010 Feb 6.PMID: 20138825 2010
|
| 41 | SOX2
|
| EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells.
|
| Riggi N, Suvà ML, De Vito C, Provero P, Stehle JC, Baumer K, Cironi L, Janiszewska M, Petricevic T, Suvà D, Tercier S, Joseph JM, Guillou L, Stamenkovic I.
|
| Genes Dev 24(9):916-32. Epub 2010 Apr 9.
2010
|
| 42 | SOX2
|
| Sox2 regulatory region 2 sequence works as a DNA nuclear targeting sequence enhancing the efficiency of an exogenous gene expression in ES cells.
|
| Funabashi H, Takatsu M, Saito M, Matsuoka H.
|
| Biochem Biophys Res Commun 400(4):554-8. Epub 2010 Aug 31.
2010
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| 43 | ANOP3, SOX2
|
| Supernumerary impacted teeth in a patient with SOX2 anophthalmia syndrome.
|
| Numakura C, Kitanaka S, Kato M, Ishikawa S, Hamamoto Y, Katsushima Y, Kimura T, Hayasaka K.
|
| Am J Med Genet A 152A(9):2355-9. 2010
|
| 44 | SOX2
|
| SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.
|
| Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, O'Kelly M, Dutt A, Rozenblatt-Rosen O, Dziunycz P, Komisarof J, Chirieac LR, Lafargue CJ, Scheble V, Wilbertz T, Ma C, Rao S, Nakagawa H, Stairs DB, Lin L, Giordano TJ, Wagner P, Minna JD, Gazdar AF, Zhu CQ, Brose MS, Cecconello I, Jr UR, Marie SK, Dahl O, Shivdasani RA, Tsao MS, Rubin MA, Wong KK, Regev A, Hahn WC, Beer DG, Rustgi AK, Meyerson M.
|
| Nat Genet 41(11):1238-42. Epub 2009 Oct 4.PMID: 19801978 2009
|
| 45 | ANOP3, SOX2
|
| Novel SOX2 partner-factor domain mutation in a four-generation family.
|
| Mihelec M, Abraham P, Gibson K, Krowka R, Susman R, Storen R, Chen Y, Donald J, Tam PP, Grigg JR, Flaherty M, Gole GA, Jamieson RV.
|
| Eur J Hum Genet 17(11):1417-22. Epub 2009 May 27.PMID: 19471311 2009
|
| 46 | ANOP3, SOX2
|
| Novel SOX2 mutations and genotype-phenotype correlation in anophthalmia and microphthalmia.
|
| Schneider A, Bardakjian T, Reis LM, Tyler RC, Semina EV.
|
| Am J Med Genet A 149A(12):2706-15.PMID: 19921648 2009
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| 47 | SOX2
|
| MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells.
|
| Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS.
|
| Cell. 137(4):647-58. 2009
|
| 48 | SOX1, SOX2, SOX9
|
| Expression of Sox1, Sox2 and Sox9 is maintained in adult human cerebellar cortex.
|
| Alcock J, Lowe J, England T, Bath P, Sottile V.
|
| Neurosci Lett. Jan 30;450(2):114-6. doi: 10.1016/j.neulet.2008.11.047. Epub 2008 Nov 27. 2009
|
| 49 | OTX2, SOX2, RAX
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| Molecular links among the causative genes for ocular malformation: Otx2 and Sox2 coregulate Rax expression.
|
| Danno H, Michiue T, Hitachi K, Yukita A, Ishiura S, Asashima M.
|
| Proc Natl Acad Sci U S A 105(14):5408-13. Epub 2008 Apr 2. 2008
|
| 50 | CPHD3, LHX3, SOX2
|
| Novel mutations in LHX3 are associated with hypopituitarism and sensorineural hearing loss.
|
| Rajab A, Kelberman D, de Castro SC, Biebermann H, Shaikh H, Pearce K, Hall CM, Shaikh G, Gerrelli D, Grueters A, Krude H, Dattani MT.
|
| Hum Mol Genet 17(14):2150-9. Epub 2008 Apr 10.
2008
|
| 51 | ANOP3, SOX2
|
| Familial recurrence of SOX2 anophthalmia syndrome: phenotypically normal mother with two affected daughters.
|
| Schneider A, Bardakjian TM, Zhou J, Hughes N, Keep R, Dorsainville D, Kherani F, Katowitz J, Schimmenti LA, Hummel M, Fitzpatrick DR, Young TL.
|
| Am J Med Genet A 146A(21):2794-8.
2008
|
| 52 | SOX2
|
| Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cells.
|
| Fong H, Hohenstein KA, Donovan PJ.
|
| Stem Cells 26(8):1931-8. Epub 2008 Apr 3.
2008
|
| 53 | ATOH1, SOX2
|
| Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea.
|
| Dabdoub A, Puligilla C, Jones JM, Fritzsch B, Cheah KS, Pevny LH, Kelley MW.
|
| Proc Natl Acad Sci U S A 105(47):18396-401. Epub 2008 Nov 14.
2008
|
| 54 | EYA1, SOX2
|
| Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear.
|
| Zou D, Erickson C, Kim EH, Jin D, Fritzsch B, Xu PX.
|
| Hum Mol Genet 17(21):3340-56. Epub 2008 Aug 4. 2008
|
| 55 | ANOP3, SOX2
|
| Novel SOX2 mutation associated with ocular coloboma in a Chinese family.
|
| Wang P, Liang X, Yi J, Zhang Q.
|
| Arch Ophthalmol 126(5):709-13.PMID: 18474784 2008
|
| 56 | SOX2
|
| Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation.
|
| Gontan C, de Munck A, Vermeij M, Grosveld F, Tibboel D, Rottier R.
|
| Dev Biol 317(1):296-309. Epub 2008 Feb 29.PMID: 18374910 2008
|
| 57 | SOX2
|
| Aberrant expression of SOX2 upregulates MUC5AC gastric foveolar mucin in mucinous cancers of the colorectum and related lesions.
|
| Park ET, Gum JR, Kakar S, Kwon SW, Deng G, Kim YS.
|
| Int J Cancer. 122(6):1253-60. 2008
|
| 58 | SOX2
|
| SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis.
|
| Otsubo T, Akiyama Y, Yanagihara K, Yuasa Y.
|
| Br J Cancer. 98(4):824-31. 2008
|
| 59 | SOX2
|
| Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells.
|
| Card DA, Hebbar PB, Li L, Trotter KW, Komatsu Y, Mishina Y, Archer TK.
|
| Mol Cell Biol. 28(20):6426-38. 2008
|
| 60 | SOX2
|
| The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer.
|
| Chen Y, Shi L, Zhang L, Li R, Liang J, Yu W, Sun L, Yang X, Wang Y, Zhang Y, Shang Y.
|
| J Biol Chem. 283(26):17969-78 2008
|
| 61 | NANOG, POU5F1, SOX2, ZNF281
|
| The transcription factor Zfp281 controls embryonic stem cell pluripotency by direct activation and repression of target genes.
|
| Wang ZX, Teh CH, Chan CM, Chu C, Rossbach M, Kunarso G, Allapitchay TB, Wong KY, Stanton LW.
|
| Stem Cells 26(11):2791-9. doi: 10.1634/stemcells.2008-0443. Epub 2008 Aug 28.
2008
|
| 62 | SOX2, ANOP3
|
| Germinal mosaicism and familial recurrence of a SOX2 mutation with highly variable phenotypic expression extending from AEG syndrome to absence of ocular involvement.
|
| Chassaing N, Gilbert-Dussardier B, Nicot F, Fermeaux V, Encha-Razavi F, Fiorenza M, Toutain A, Calvas P.
|
| Am J Med Genet A 143(3):289-91. No abstract available. 2007
|
| 63 | NANOG, POU5F1, SOX2, ZIC3
|
| Zic3 is required for maintenance of pluripotency in embryonic stem cells.
|
| Lim LS, Loh YH, Zhang W, Li Y, Chen X, Wang Y, Bakre M, Ng HH, Stanton LW.
|
| Mol Biol Cell 18(4):1348-58. Epub 2007 Jan 31.
2007
|
| 64 | SOX2, ANOP3
|
| Mutations in SOX2 cause anophthalmia-esophageal-genital (AEG) syndrome.
|
| Williamson KA, Hever AM, Rainger J, Rogers RC, Magee A, Fiedler Z, Keng WT, Sharkey FH, McGill N, Hill CJ, Schneider A, Messina M, Turnpenny PD, Fantes JA, van Heyningen V, FitzPatrick DR.
|
| Hum Mol Genet 15(9):1413-22. Epub 2006 Mar 16. 2006
|
| 65 | PAX6, SOX2, OTX2
|
| Developmental malformations of the eye: the role of PAX6, SOX2 and OTX2.
|
| Hever AM, Williamson KA, van Heyningen V.
|
| Clin Genet 69(6):459-70. 2006
|
| 66 | SOX2, ANOP3
|
| Anophthalmia-esophageal atresia syndrome caused by an SOX2 gene deletion in monozygotic twin brothers with markedly discordant phenotypes.
|
| Zenteno JC, Perez-Cano HJ, Aguinaga M.
|
| Am J Med Genet A 140(18):1899-903. 2006
|
| 67 | SOX2
|
| SOX2 is a dose-dependent regulator of retinal neural progenitor competence.
|
| Taranova OV, Magness ST, Fagan BM, Wu Y, Surzenko N, Hutton SR, Pevny LH.
|
| Genes Dev 20(9):1187-202. 2006
|
| 68 | SOX2, ANOP3
|
| Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans.
|
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