| 1 | SORCS2
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| SorCS2 is required for social memory and trafficking of the NMDA receptor.
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| Yang J, Ma Q, Dincheva I, Giza J, Jing D, Marinic T, Milner TA, Rajadhyaksha A, Lee FS, Hempstead BL.
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| Mol Psychiatry. Jan 27. doi: 10.1038/s41380-020-0650-7. Online ahead of print 2020
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| 2 | SLC1A1, SORCS2
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| SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology.
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| Malik AR, Szydlowska K, Nizinska K, Asaro A, van Vliet EA, Popp O, Dittmar G, Fritsche-Guenther R, Kirwan JA, Nykjaer A, Lukasiuk K, Aronica E, Willnow TE.
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| Cell Rep. Mar 5;26(10):2792-2804.e6. doi: 10.1016/j.celrep.2019.02.027 2019
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| 3 | SORCS2
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| Structural insights into SorCS2-Nerve Growth Factor complex formation.
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| Leloup N, Chataigner LMP, Janssen BJC.
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| Nat Commun. Jul 30;9(1):2979. doi: 10.1038/s41467-018-05405-z 2018
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| 4 | SORCS2, SORT1
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| Highly segregated localization of the functionally related vps10p receptors sortilin and SorCS2 during neurodevelopment.
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| Boggild S, Molgaard S, Glerup S, Nyengaard JR.
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| J Comp Neurol. Jun 1;526(8):1267-1286. doi: 10.1002/cne.24403. Epub 2018 Feb 20 2018
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| 5 | GRIN2A, SORCS2
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| SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease.
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| Ma Q, Yang J, Milner TA, Vonsattel JG, Palko ME, Tessarollo L, Hempstead BL.
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| JCI Insight. May 4;2(9):e88995. doi: 10.1172/jci.insight.88995. eCollection 2017 May 4 2017
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| 6 | SORCS2
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| Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear.
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| Forge A, Taylor RR, Dawson SJ, Lovett M, Jagger DJ.
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| PLoS Genet. Mar 27;13(3):e1006692. doi: 10.1371/journal.pgen.1006692. eCollection 2017 Mar. 2017
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| 7 | SORCS2
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| SorCS2 is required for BDNF-dependent plasticity in the hippocampus.
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| Glerup S, Bolcho U, Mølgaard S, Bøggild S, Vaegter CB, Smith AH, Nieto-Gonzalez JL, Ovesen PL, Pedersen LF, Fjorback AN, Kjolby M, Login H, Holm MM, Andersen OM, Nyengaard JR, Willnow TE, Jensen K, Nykjaer A.
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| Mol Psychiatry. Dec;21(12):1740-1751. doi: 10.1038/mp.2016.108. Epub 2016 Jul 26 2016
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| 8 | SORCS1, SORCS2, SORCS3, SORL1
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| The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review.
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| Reitz C.
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| Mol Genet Genomics. Apr;290(2):413-27. doi: 10.1007/s00438-014-0939-9. Epub 2014 Oct 21 2015
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| 9 | SORCS2
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| SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.
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| Glerup S, Olsen D, Vaegter CB, Gustafsen C, Sjoegaard SS, Hermey G, Kjolby M, Molgaard S, Ulrichsen M, Boggild S, Skeldal S, Fjorback AN, Nyengaard JR, Jacobsen J, Bender D, Bjarkam CR, Sørensen ES, Füchtbauer EM, Eichele G, Madsen P, Willnow TE, Petersen CM, Nykjaer A.
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| Neuron Jun 4;82(5):1074-87. doi: 10.1016/j.neuron.2014.04.022 2014
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| 10 | SORCS1, SORCS2, SORCS3, SORL1
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| Vps10 family proteins and the retromer complex in aging-related neurodegeneration and diabetes.
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| Lane RF, St George-Hyslop P, Hempstead BL, Small SA, Strittmatter SM, Gandy S.
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| Version 2. J Neurosci. Oct 10;32(41):14080-6. doi: 10.1523/JNEUROSCI.3359-12.2012 2012
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| 11 | APP, IGF2R, PACS1, SORCS1, SORCS2, SORCS3, SORL1, SORT1
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| VPS10P-domain receptors - regulators of neuronal viability and function.
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| Willnow TE, Petersen CM, Nykjaer A.
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| Nat Rev Neurosci. 9(12):899-909. 2009
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| 12 | SORCS2, SORCS3, SORS1
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| The three sorCS genes are differentially expressed and regulated by synaptic activity.
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| Hermey G, Plath N, Hübner CA, Kuhl D, Schaller HC, Hermans-Borgmeyer I.
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| J Neurochem 88(6):1470-6.
2004
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| 13 | SORCS1, SORCS2, SORCS3, SORL1, SORT1
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| The genes for the human VPS10 domain-containing receptors are large and contain many small exons.
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| Hampe W, Rezgaoui M, Hermans-Borgmeyer I, Schaller HC.
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| Hum Genet 108(6):529-36. 2001
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