| 1 | SOD1
|
| Non-enzymatic role of SOD1 in intestinal stem cell growth
|
| Wang YC, Leng XX, Zhou CB, Lu SY, Tsang CK, Xu J, Zhang MM, Chen HM, Fang JY.
|
| Cell Death Dis. Oct 20;13(10):882. doi: 10.1038/s41419-022-05267-w. 2022
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| 2 | ALS1, SOD1
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| Altered SOD1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord
|
| Trist BG, Genoud S, Roudeau S, Rookyard A, Abdeen A, Cottam V, Hare DJ, White M, Altvater J, Fifita JA, Hogan A, Grima N, Blair IP, Kysenius K, Crouch PJ, Carmona A, Rufin Y, Claverol S, Van Malderen S, Falkenberg G, Paterson DJ, Smith B, Troakes C, Vance C, Shaw CE, Al-Sarraj S, Cordwell S, Halliday G, Ortega R, Double KL.
|
| Brain. Sep 14;145(9):3108-3130. doi: 10.1093/brain/awac165 2022
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| 3 | SOD1
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| SOD1-interacting proteins: Roles of aggregation cores and protein degradation systems
|
| Une M, Yamakawa M, Watanabe Y, Uchino K, Honda N, Adachi M, Nakanishi M, Umezawa A, Kawata Y, Nakashima K, Hanajima R.
|
| Neurosci Res. Sep;170:295-305. doi: 10.1016/j.neures.2020.07.010. Epub 2020 Jul 26. 2021
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| 4 | CCS, SOD1
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| Molecular and pharmacological chaperones for SOD1
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| Wright GSA.
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| Biochem Soc Trans. Aug 28;48(4):1795-1806. doi: 10.1042/BST20200318 2020
|
| 5 | SOD1
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| Nucleation and kinetics of SOD1 aggregation in human cells for ALS1
|
| Workman A.
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| Mol Cell Biochem. Mar;466(1-2):117-128. doi: 10.1007/s11010-020-03693-y. Epub 2020 Feb 13. 2020
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| 6 | SOD1, STHAP
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| SOD1 deficiency: a novel syndrome distinct from amyotrophic lateral sclerosis.
|
| Park JH, Elpers C, Reunert J, McCormick ML, Mohr J, Biskup S, Schwartz O, Rust S, Grüneberg M, Seelhöfer A, Schara U, Boltshauser E, Spitz DR, Marquardt T.
|
| Brain Aug 1;142(8):2230-2237. doi: 10.1093/brain/awz182. 2019
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| 7 | SOD1, STHAP
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| Phenotype in an Infant with SOD1 Homozygous Truncating Mutation
|
| Andersen PM, Nordström U, Tsiakas K, Johannsen J, Volk AE, Bierhals T, Zetterström P, Marklund SL, Hempel M, Santer R.
|
| N Engl J Med. Aug 1;381(5):486-488. doi: 10.1056/NEJMc1905039. Epub 2019 Jul 17. 2019
|
| 8 | ALS1, SOD1
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| Structural Properties and Interaction Partners of Familial ALS-Associated SOD1 Mutants
|
| Huai J, Zhang Z.
|
| Front Neurol. May 21;10:527. doi: 10.3389/fneur.2019.00527. 2019
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| 9 | RAC1, SOD1
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| SOD1 stimulates lamellipodial protrusions in Neuro 2A cell lines
|
| Ferrari I, Verpelli C, Crespi A, Sala C, Fornasari D, Pietrini G.
|
| Commun Integr Biol. Aug 9;11(3):1-7. doi: 10.1080/19420889.2018.1486652. 2018
|
| 10 | SOD1
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| Aggregated SOD1 causes selective death of cultured human motor neurons.
|
| Benkler C, O'Neil AL, Slepian S, Qian F, Weinreb PH, Rubin LL.
|
| Sci Rep. Nov 6;8(1):16393. doi: 10.1038/s41598-018-34759-z. 2018
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| 11 | DERL1, SOD1
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| A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.
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| Tsuburaya N, Homma K, Higuchi T, Balia A, Yamakoshi H, Shibata N, Nakamura S, Nakagawa H, Ikeda SI, Umezawa N, Kato N, Yokoshima S, Shibuya M, Shimonishi M, Kojima H, Okabe T, Nagano T, Naguro I, Imamura K, Inoue H, Fujisawa T, Ichijo H.
|
| Nat Commun. Jul 10;9(1):2668. doi: 10.1038/s41467-018-05127-2. 2018
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| 12 | SCN3A, SOD1
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| Mutant SOD1 protein increases Nav1.3 channel excitability.
|
| Kubat Öktem E, Mruk K, Chang J, Akin A, Kobertz WR, Brown RH Jr.
|
| J Biol Phys 42(3):351-70. doi: 10.1007/s10867-016-9411-x. Epub 2016 Apr 12. Erratum in: J Biol Phys. 2016 Jun;42(3):371.
2016
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| 13 | ALS1, SOD1
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| Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways
|
| Silverman JM, Fernando SM, Grad LI, Hill AF, Turner BJ, Yerbury JJ, Cashman NR.
|
| Cell Mol Neurobiol. Apr;36(3):377-81. doi: 10.1007/s10571-015-0294-3. Epub 2016 Feb 23 2016
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| 14 | SOD1
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| Copper Homeostasis as a Therapeutic Target in Amyotrophic Lateral Sclerosis with SOD1 Mutations
|
| Tokuda E, Furukawa Y.
|
| Int J Mol Sci. Apr 28;17(5):636. doi: 10.3390/ijms17050636. 2016
|
| 15 | ALS1, SOD1
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| SOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesis
|
| Tafuri F, Ronchi D, Magri F, Comi GP, Corti S.
|
| Front Cell Neurosci. Aug 25;9:336. doi: 10.3389/fncel.2015.00336. 2015
|
| 16 | HDAC6, SOD1
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| HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation.
|
| Gal J, Chen J, Barnett KR, Yang L, Brumley E, Zhu H.
|
| J Biol Chem 288(21):15035-45. doi: 10.1074/jbc.M112.431957. Epub 2013 Apr 11.
2013
|
| 17 | ALS1, SOD1
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| Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.
|
| Pickles S, Destroismaisons L, Peyrard SL, Cadot S, Rouleau GA, Brown RH Jr, Julien JP, Arbour N, Vande Velde C.
|
| Hum Mol Genet 22(19):3947-59. doi: 10.1093/hmg/ddt249. Epub 2013 Jun 4.
2013
|
| 18 | DERL1, SOD1
|
| SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency.
|
| Homma K, Fujisawa T, Tsuburaya N, Yamaguchi N, Kadowaki H, Takeda K, Nishitoh H, Matsuzawa A, Naguro I, Ichijo H.
|
| Mol Cell 52(1):75-86. doi: 10.1016/j.molcel.2013.08.038. Epub 2013 Sep 26.
2013
|
| 19 | ALS1, SOD1
|
| Disulfide scrambling describes the oligomer formation of superoxide dismutase (SOD1) proteins in the familial form of amyotrophic lateral sclerosis.
|
| Toichi K, Yamanaka K, Furukawa Y.
|
| J Biol Chem 288(7):4970-80. doi: 10.1074/jbc.M112.414235. Epub 2012 Dec 21.
2013
|
| 20 | CCS, SOD1
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| Human copper chaperone for superoxide dismutase 1 mediates its own oxidation-dependent import into mitochondria.
|
| Suzuki Y, Ali M, Fischer M, Riemer J.
|
| Nat Commun 4:2430. doi: 10.1038/ncomms3430.
2013
|
| 21 | SOD1
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| Palmitoylation of superoxide dismutase 1 (SOD1) is increased for familial amyotrophic lateral sclerosis-linked SOD1 mutants
|
| Antinone SE, Ghadge GD, Lam TT, Wang L, Roos RP, Green WN.
|
| J Biol Chem. Jul 26;288(30):21606-17. doi: 10.1074/jbc.M113.487231. Epub 2013 Jun 12. 2013
|
| 22 | GLI1, PTCH1, SOD1
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| Inhibition of sonic hedgehog signaling aggravates brain damage associated with the down-regulation of Gli1, Ptch1 and SOD1 expression in acute ischemic stroke.
|
| Ji H, Miao J, Zhang X, Du Y, Liu H, Li S, Li L.
|
| Neurosci Lett 506(1):1-6. doi: 10.1016/j.neulet.2011.11.027. Epub 2011 Nov 25.
2012
|
| 23 | CCS, SOD1
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| Human superoxide dismutase 1 (hSOD1) maturation through interaction with human copper chaperone for SOD1 (hCCS).
|
| Banci L, Bertini I, Cantini F, Kozyreva T, Massagni C, Palumaa P, Rubino JT, Zovo K.
|
| Proc Natl Acad Sci U S A 109(34):13555-60. doi: 10.1073/pnas.1207493109. Epub 2012 Aug 6.
2012
|
| 24 | MTRNR2L1, SOD1
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| Humanin protects cortical neurons from ischemia and reperfusion injury by the increased activity of superoxide dismutase.
|
| Zhao ST, Huang XT, Zhang C, Ke Y.
|
| Neurochem Res 37(1):153-60. doi: 10.1007/s11064-011-0593-0.
2012
|
| 25 | SOD1
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| Retinal ganglion cell loss in superoxide dismutase 1 deficiency.
|
| Yuki K, Ozawa Y, Yoshida T, Kurihara T, Hirasawa M, Ozeki N, Shiba D, Noda K, Ishida S, Tsubota K.
|
| Invest Ophthalmol Vis Sci. 52(7):4143-50. 2011
|
| 26 | BDNF, NTRK2, SOD1
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| The in vivo contribution of motor neuron TrkB receptors to mutant SOD1 motor neuron disease.
|
| Zhai J, Zhou W, Li J, Hayworth CR, Zhang L, Misawa H, Klein R, Scherer SS, Balice-Gordon RJ, Kalb RG.
|
| Hum Mol Genet. 20(21):4116-31 2011
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| 27 | ALS1, CCS, SOD1
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| Effect of CCS on the accumulation of FALS SOD1 mutant-containing aggregates and on mitochondrial translocation of SOD1 mutants: implication of a free radical hypothesis.
|
| Kim HK, Chung YW, Chock PB, Yim MB.
|
| Arch Biochem Biophys 509(2):177-85. doi: 10.1016/j.abb.2011.02.014. Epub 2011 Feb 24.
2011
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| 28 | ALS1, SOD1
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| Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice.
|
| Wong M, Martin LJ.
|
| Hum Mol Genet 19(11):2284-302. Epub 2010 Mar 10.PMID: 20223753 2010
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| 29 | ALS1, SOD1
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| Mutation-dependent polymorphism of Cu,Zn-superoxide dismutase aggregates in the familial form of amyotrophic lateral sclerosis.
|
| Furukawa Y, Kaneko K, Yamanaka K, Nukina N.
|
| J Biol Chem 285(29):22221-31. Epub 2010 Apr 19.PMID: 20404329 2010
|
| 30 | ALS1, ALS10, ALS6, ALS8, ALS9, ANG, FUS, SOD1, TARDBP, VAPB
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| SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype-phenotype correlations.
|
| Millecamps S, Salachas F, Cazeneuve C, Gordon P, Bricka B, Camuzat A, Guillot-Noël L, Russaouen O, Bruneteau G, Pradat PF, Le Forestier N, Vandenberghe N, Danel-Brunaud V, Guy N, Thauvin-Robinet C, Lacomblez L, Couratier P, Hannequin D, Seilhean D, Le Ber I, Corcia P, Camu W, Brice A, Rouleau G, LeGuern E, Meininger V.
|
| J Med Genet 47(8):554-60. Epub 2010 Jun 24.PMID: 20577002 2010
|
| 31 | ALS1, BCL2, SOD1
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| ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2.
|
| Pedrini S, Sau D, Guareschi S, Bogush M, Brown RH Jr, Naniche N, Kia A, Trotti D, Pasinelli P.
|
| Hum Mol Genet 19(15):2974-86. Epub 2010 May 11.PMID: 20460269 2010
|
| 32 | ALS1, SOD1
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| A novel SOD1 splice site mutation associated with familial ALS revealed by SOD activity analysis.
|
| Birve A, Neuwirth C, Weber M, Marklund SL, Nilsson AC, Jonsson PA, Andersen PM.
|
| Hum Mol Genet 19(21):4201-6. Epub 2010 Aug 13.
2010
|
| 33 | ALS1, SOD1
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| Deficits in axonal transport precede ALS symptoms in vivo.
|
| Bilsland LG, Sahai E, Kelly G, Golding M, Greensmith L, Schiavo G.
|
| Proc Natl Acad Sci U S A 107(47):20523-8. Epub 2010 Nov 8.
2010
|
| 34 | ALS1, SOD1
|
| ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import.
|
| Li Q, Vande Velde C, Israelson A, Xie J, Bailey AO, Dong MQ, Chun SJ, Roy T, Winer L, Yates JR, Capaldi RA, Cleveland DW, Miller TM.
|
| Proc Natl Acad Sci U S A 107(49):21146-51. Epub 2010 Nov 15.
2010
|
| 35 | SOD1
|
| The Arabidopsis DJ-1a protein confers stress protection through cytosolic SOD activation.
|
| Xu XM, Lin H, Maple J, Björkblom B, Alves G, Larsen JP, Møller SG.
|
| J Cell Sci. 123(Pt 10):1644-51. 2010
|
| 36 | SOD1, SOD2, SOD3
|
| Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD2.
|
| Takada S, Inoue E, Tano K, Yoshii H, Abe T, Yoshimura A, Akita M, Tada S, Watanabe M, Seki M, Enomoto T.
|
| Biochem Biophys Res Commun 379(2):233-8. Epub 2008 Dec 25.
2009
|
| 37 | ALS1, SOD1
|
| SOD1 and cognitive dysfunction in familial amyotrophic lateral sclerosis.
|
| Wicks P, Abrahams S, Papps B, Al-Chalabi A, Shaw CE, Leigh PN, Goldstein LH.
|
| J Neurol 256(2):234-41. Epub 2009 Mar 1.
2009
|
| 38 | SOD1
|
| Expression of amyotrophic lateral sclerosis-linked SOD1 mutant increases the neurotoxic potential of microglia via TLR2
|
| Liu Y, Hao W, Dawson A, Liu S, Fassbender K.
|
| J Biol Chem. 284(6):3691-9 2009
|
| 39 | ALS1, SOD1
|
| Functional features cause misfolding of the ALS-provoking enzyme SOD1.
|
| Nordlund A, Leinartaite L, Saraboji K, Aisenbrey C, Gröbner G, Zetterström P, Danielsson J, Logan DT, Oliveberg M.
|
| Proc Natl Acad Sci U S A 106(24):9667-72. Epub 2009 Jun 2.
2009
|
| 40 | ALS1, SOD1
|
| Familial amyotrophic lateral sclerosis-linked mutant SOD1 aberrantly interacts with tubulin.
|
| Kabuta T, Kinugawa A, Tsuchiya Y, Kabuta C, Setsuie R, Tateno M, Araki T, Wada K.
|
| Biochem Biophys Res Commun 387(1):121-6. Epub 2009 Jul 1.PMID: 19576169 2009
|
| 41 | ALS1, SOD1
|
| Variation in aggregation propensities among ALS-associated variants of SOD1: correlation to human disease.
|
| Prudencio M, Hart PJ, Borchelt DR, Andersen PM.
|
| Hum Mol Genet 18(17):3217-26. Epub 2009 May 30.PMID: 19483195 2009
|
| 42 | AMFR, ATXN3, SOD1
|
| Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.
|
| Ying Z, Wang H, Fan H, Zhu X, Zhou J, Fei E, Wang G.
|
| Hum Mol Genet 18(22):4268-81. Epub 2009 Aug 6.PMID: 19661182 2009
|
| 43 | CCS, SOD1
|
| The right to choose: multiple pathways for activating copper,zinc superoxide dismutase.
|
| Leitch JM, Yick PJ, Culotta VC.
|
| J Biol Chem 284(37):24679-83. Epub 2009 Jul 8. Review.PMID: 19586921 2009
|
| 44 | SOD1
|
| Mitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generation.
|
| Yonashiro R, Sugiura A, Miyachi M, Fukuda T, Matsushita N, Inatome R, Ogata Y, Suzuki T, Dohmae N, Yanagi S.
|
| Mol Biol Cell. 20(21):4524-30. 2009
|
| 45 | SOD1
|
| Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis.
|
| Awano T, Johnson GS, Wade CM, Katz ML, Johnson GC, Taylor JF, Perloski M, Biagi T, Baranowska I, Long S, March PA, Olby NJ, Shelton GD, Khan S, O'Brien DP, Lindblad-Toh K, Coates JR.
|
| Proc Natl Acad Sci U S A. 106(8):2794-9. 2009
|
| 46 | SOD1
|
| Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3.
|
| Tateno M, Kato S, Sakurai T, Nukina N, Takahashi R, Araki T.
|
| Hum Mol Genet. 18(5):942-55 2009
|
| 47 | SOD1
|
| Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis.
|
| Cheroni C, Marino M, Tortarolo M, Veglianese P, De Biasi S, Fontana E, Zuccarello LV, Maynard CJ, Dantuma NP, Bendotti C.
|
| Hum Mol Genet. 18(1):82-96. 2009
|
| 48 | SOD1
|
| Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse.
|
| Wang L, Deng HX, Grisotti G, Zhai H, Siddique T, Roos RP.
|
| Hum Mol Genet. 18(9):1642-51. 2009
|
| 49 | ALS1, SOD1
|
| Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis.
|
| Furukawa Y, Kaneko K, Yamanaka K, O'Halloran TV, Nukina N.
|
| J Biol Chem 283(35):24167-76. Epub 2008 Jun 13.
2008
|
| 50 | ALS1, ASK1, SOD1
|
| ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.
|
| Nishitoh H, Kadowaki H, Nagai A, Maruyama T, Yokota T, Fukutomi H, Noguchi T, Matsuzawa A, Takeda K, Ichijo H.
|
| Genes Dev 22(11):1451-64.
2008
|
| 51 | ALS1, SOD1
|
| ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration.
|
| Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV.
|
| Nat Neurosci 11(4):420-2. Epub 2008 Mar 16. 2008
|
| 52 | KARS, SDCBP, SOD1
|
| Lysyl-tRNA synthetase is a target for mutant SOD1 toxicity in mitochondria.
|
| Kawamata H, Magrané J, Kunst C, King MP, Manfredi G.
|
| J Biol Chem 283(42):28321-8. Epub 2008 Aug 20. 2008
|
| 53 | ALS1, SOD1
|
| SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model.
|
| Harraz MM, Marden JJ, Zhou W, Zhang Y, Williams A, Sharov VS, Nelson K, Luo M, Paulson H, Schöneich C, Engelhardt JF.
|
| J Clin Invest 118(2):659-70.PMID: 1821939 2008
|
| 54 | CCS, SOD1
|
| Different regulation of wild-type and mutant Cu,Zn superoxide dismutase localization in mammalian mitochondria.
|
| Kawamata H, Manfredi G.
|
| Hum Mol Genet 17(21):3303-17. Epub 2008 Aug 13.PMID: 18703498 2008
|
| 55 | ALS1, SOD1
|
| Familial amyotrophic lateral sclerosis with Gly93Ser mutation in Cu/Zn superoxide dismutase: a clinical and neuropathological study.
|
| Suzuki M, Irie T, Watanabe T, Mikami H, Yamazaki T, Oyanagi K, Ono S.
|
| J Neurol Sci 268(1-2):140-4. Epub 2008 Jan 14.PMID: 18191946 2008
|
| 56 | ALS1,SOD1
|
| Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability.
|
| Wang J, Caruano-Yzermans A, Rodriguez A, Scheurmann JP, Slunt HH, Cao X, Gitlin J, Hart PJ, Borchelt DR.
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| J Biol Chem 282(1):345-52. Epub 2006 Nov 8. 2007
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| 57 | ALS1,SOD1
|
| Mutation of SOD1 in ALS: a gain of a loss of function.
|
| Sau D, De Biasi S, Vitellaro-Zuccarello L, Riso P, Guarnieri S, Porrini M, Simeoni S, Crippa V, Onesto E, Palazzolo I, Rusmini P, Bolzoni E, Bendotti C, Poletti A.
|
| Hum Mol Genet 16(13):1604-18. Epub 2007 May 15. 2007
|
| 58 | SOD1
|
| Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis.
|
| Gruzman A, Wood WL, Alpert E, Prasad MD, Miller RG, Rothstein JD, Bowser R, Hamilton R, Wood TD, Cleveland DW, Lingappa VR, Liu J.
|
| Proc Natl Acad Sci U S A 104(30):12524-9. Epub 2007 Jul 16. 2007
|
| 59 | SMN1, SOD1, HFE, APEX1, ANG
|
| Genetics of sporadic amyotrophic lateral sclerosis.
|
| Schymick JC, Talbot K, Traynor BJ.
|
| Hum Mol Genet 16 Spec No 2:R233-42. 2007
|
| 60 | SOD1, ALS1
|
| Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins.
|
| Sandelin E, Nordlund A, Andersen PM, Marklund SS, Oliveberg M.
|
| J Biol Chem 282(29):21230-6. Epub 2007 May 18. 2007
|
| 61 | SOD1, ALS1
|
| Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.
|
| De Vos KJ, Chapman AL, Tennant ME, Manser C, Tudor EL, Lau KF, Brownlees J, Ackerley S, Shaw PJ, McLoughlin DM, Shaw CE, Leigh PN, Miller CC, Grierson AJ.
|
| Hum Mol Genet 16(22):2720-8. Epub 2007 Aug 28. 2007
|
| 62 | SOD1
|
| An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS
|
| Rakhit R, Robertson J, Vande Velde C, Horne P, Ruth DM, Griffin J, Cleveland DW, Cashman NR, Chakrabartty A.
|
| Nat Med. 13(6):754-9 2007
|
| 63 | ALS1, SOD1
|
| Analysis of a genetic defect in the TATA box of the SOD1 gene in a patient with familial amyotrophic lateral sclerosis.
|
| Niemann S, Broom WJ, Brown RH Jr.
|
| Muscle Nerve 36(5):704-7.PMID: 17636481 2007
|
| 64 | SOD1
|
| Activation of brain calcineurin (Cn) by Cu-Zn superoxide dismutase (SOD1) depends on direct SOD1-Cn protein interactions occurring in vitro and in vivo.
|
| Agbas A, Hui D, Wang X, Tek V, Zaidi A, Michaelis EK.
|
| Biochem J. 405(1):51-9. 2007
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| 65 | SOD1
|
| Redox modifier genes in amyotrophic lateral sclerosis in mice.
|
| Marden JJ, Harraz MM, Williams AJ, Nelson K, Luo M, Paulson H, Engelhardt JF.
|
| J Clin Invest. 117(10):2913-9. 2007
|
| 66 | ALS1, SOD1
|
| Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model.
|
| Kikuchi H, Almer G, Yamashita S, Guegan C, Nagai M, Xu Z, Sosunov AA, McKhann GM 2nd, Przedborski S.
|
| Proc Natl Acad Sci U S A 103(15):6025-30. Epub 2006 Apr 4. 2006
|
| 67 | SOD1, ALS1
|
| Onset and progression in inherited ALS determined by motor neurons and microglia.
|
| Boillee S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW.
|
| Science 312(5778):1389-92. 2006
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| 68 | SOD1
|
| Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials.
|
| Ferri A, Cozzolino M, Crosio C, Nencini M, Casciati A, Gralla EB, Rotilio G, Valentine JS, Carri MT.
|
| Proc Natl Acad Sci U S A 103(37):13860-5. Epub 2006 Aug 30. 2006
|
| 69 | SOD1
|
| Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis.
|
| Urushitani M, Sik A, Sakurai T, Nukina N, Takahashi R, Julien JP.
|
| Nat Neurosci. 9(1):108-18. 2006
|
| 70 | SOD1
|
| Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1.
|
| Aquilano K, Vigilanza P, Rotilio G, Ciriolo MR.
|
| FASEB J. 20(10):1683-5. 2006
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| 71 | SOD1
|
| Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis.
|
| Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK.
|
| Proc Natl Acad Sci U S A. 103(51):19546-51. 2006
|
| 72 | SOD1, ALS1
|
| Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.
|
| Raoul C, Abbas-Terki T, Bensadoun JC, Guillot S, Haase G, Szulc J, Henderson CE, Aebischer P.
|
| Nat Med 11(4):423-8. Epub 2005 Mar 13. 2005
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| 73 | ALS1, SOD1
|
| Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation.
|
| Wang J, Xu G, Li H, Gonzales V, Fromholt D, Karch C, Copeland NG, Jenkins NA, Borchelt DR.
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| Hum Mol Genet 14(16):2335-47. Epub 2005 Jul 6. 2005
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| 74 | CCS, SOD1
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