1 | RELN, SOCS6, SOCS7
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| Cortical Layer Inversion and Deregulation of Reelin Signaling in the Absence of SOCS6 and SOCS7.
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| Lawrenson ID, Krebs DL, Linossi EM, Zhang JG, McLennan TJ, Collin C, McRae HM, Kolesnik TB, Koh K, Britto JM, Kueh AJ, Sheikh BN, El-Saafin F, Nicola NA, Tan SS, Babon JJ, Nicholson SE, Alexander WS, Thomas T, Voss AK.
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| Cereb Cortex 27(1):576-588. doi: 10.1093/cercor/bhv253.
2017
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2 | FLT3, SOCS6
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| Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3.
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| Kazi JU, Sun J, Phung B, Zadjali F, Flores-Morales A, Rönnstrand L.
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| J Biol Chem 287(43):36509-17. doi: 10.1074/jbc.M112.376111. Epub 2012 Sep 5.
2012
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3 | SOCS5, SOCS6
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| SOCS5 and SOCS6 have similar expression patterns in normal and cancer tissues.
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| Yoon S, Yi YS, Kim SS, Kim JH, Park WS, Nam SW.
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| Tumour Biol 33(1):215-21. doi: 10.1007/s13277-011-0264-4. Epub 2011 Nov 12.
2012
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4 | SOCS6
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| SOCS6, down-regulated in gastric cancer, inhibits cell proliferation and colony formation.
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| Lai RH, Hsiao YW, Wang MJ, Lin HY, Wu CW, Chi CW, Li AF, Jou YS, Chen JY.
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| Cancer Lett 288(1):75-85. Epub 2009 Jul 30.PMID: 19646809 2010
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5 | LCK, SOCS6
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| SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradation.
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| Choi YB, Son M, Park M, Shin J, Yun Y.
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| J Biol Chem 285(10):7271-80. Epub 2009 Dec 10. 2010
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6 | SOCS6
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| Genomic organization and functional characterization of the promoter for the human suppressor of cytokine signaling 6 gene.
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| Lai RH, Wang MJ, Yang SH, Chen JY.
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| Gene 448(1):64-73. Epub 2009 Aug 28.PMID: 19716864 2009
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7 | CISH, SOCS1, SOCS2, SOCS3, SOCS6, SOCS7
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| Increased cytoplasmic levels of CIS, SOCS1, SOCS2, or SOCS3 are required for nuclear translocation.
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| Lee KH, Moon KJ, Kim HS, Yoo BC, Park S, Lee H, Kwon S, Lee ES, Yoon S.
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| FEBS Lett 582(15):2319-24. Epub 2008 Jun 4. 2008
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8 | SOCS1, SOCS3, SOCS6
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| Suppressors of cytokine-signaling proteins induce insulin resistance in the retina and promote survival of retinal cells.
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| Liu X, Mameza MG, Lee YS, Eseonu CI, Yu CR, Kang Derwent JJ, Egwuagu CE.
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| Diabetes 57(6):1651-8. Epub 2008 Mar 20.PMID: 18356406 2008
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9 | PRKCD,SOCS6
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| Increased SOCS6 stability with PMA requires its N-terminal region and the Erk pathway via Pkcdelta activation.
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| Hwang MN, Ha TH, Park J, Shim J, Lee H, Kim YN, Lee ES, Yoon S.
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| Biochem Biophys Res Commun 354(1):184-9. Epub 2006 Dec 29. 2007
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10 | SOCS6
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| The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins.
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| Bayle J, Lopez S, Iwa• K, Dubreuil P, De Sepulveda P.
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| FEBS Lett 580(11):2609-14. Epub 2006 Apr 21. 2006
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11 | CD226, CDH7, SOCS6
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| Prognostic and predictive relevance of DNAM-1, SOCS6 and CADH-7 genes on chromosome 18q in colorectal cancer.
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| Storojeva I, Boulay JL, Ballabeni P, Buess M, Terracciano L, Laffer U, Mild G, Herrmann R, Rochlitz C.
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| Oncology 68(2-3):246-55. Epub 2005 Jul 7. 2005
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12 | SOCS6
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| Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling.
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| Bayle J, Letard S, Frank R, Dubreuil P, De Sepulveda P.
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| J Biol Chem 279(13):12249-59. Epub 2004 Jan 5. 2004
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13 | SOCS1, SOCS2, SOCS3, SOCS6, SOCS5, SOCS7, SOCS4
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| SOCS1 methylation in patients with newly diagnosed acute myeloid leukemia.
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| Chen CY, Tsay W, Tang JL, Shen HL, Lin SW, Huang SY, Yao M, Chen YC, Shen MC, Wang CH, Tien HF.
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| Genes Chromosomes Cancer 37(3):300-5. 2003
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14 | SOCS6
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| SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.
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| Krebs DL, Uren RT, Metcalf D, Rakar S, Zhang JG, Starr R, De Souza DP, Hanzinikolas K, Eyles J, Connolly LM, Simpson RJ, Nicola NA, Nicholson SE, Baca M, Hilton DJ, Alexander WS.
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| Mol Cell Biol 22(13):4567-78. 2002
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15 | ASB10, ASB11, ASB12, ASB13, ASB14, ASB15, ASB16, ASB17, ASB18, ASB5, ASB6, ASB7, ASB8, ASB9, NEURL2, SOCS4, SOCS6, SPSB1, SPSB2, SPSB3, SPSB4, TULP4, WSB2
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| The SOCS box: a tale of destruction and degradation.
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| Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
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| Trends Biochem Sci 27(5):235-41. Review. 2002
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16 | CISH, SOCS3, SOCS6
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| Cloning and characterization of novel CIS family genes.
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| Masuhara M, Sakamoto H, Matsumoto A, Suzuki R, Yasukawa H, Mitsui K,Wakioka T, Tanimura S, Sasaki A, Misawa H, Yokouchi M, Ohtsubo M, Yoshimura A.
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| Biochem Biophys Res Commun 239(2):439-46. 1997
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