| 1 | EFNA1, EPHA2, SOCS2
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| SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms.
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| Pilling C, Cooper JA.
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| Sci Rep. Sep 7;7(1):10838. doi: 10.1038/s41598-017-11040-3 2017
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| 2 | FLT3, SOCS2
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| Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling.
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| Kazi JU, Rönnstrand L.
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| Mol Oncol 7(3):693-703. doi: 10.1016/j.molonc.2013.02.020. Epub 2013 Mar 19.
2013
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| 3 | CUL5, ELOB, ELOC, SOCS2
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| Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
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| Kim YK, Kwak MJ, Ku B, Suh HY, Joo K, Lee J, Jung JU, Oh BH.
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| Acta Crystallogr D Biol Crystallogr. Aug;69(Pt 8):1587-97. doi: 10.1107/S0907444913011220. Epub 2013 Jul 20 2013
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| 4 | SOCS1, SOCS2, SOCS3
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| Expression of SOCS1, SOCS2, and SOCS3 in growth hormone-stimulated skin fibroblasts from children with idiopathic short stature.
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| Ocaranza P, Morales F, Román R, Ińiguez G, Fernando C.
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| J Pediatr Endocrinol Metab 25(3-4):273-8.
2012
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| 5 | ELOB, ELOC, SOCS2
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| The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels.
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| Vesterlund M, Zadjali F, Persson T, Nielsen ML, Kessler BM, Norstedt G, Flores-Morales A.
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| PLoS One 6(9):e25358. doi: 10.1371/journal.pone.0025358. Epub 2011 Sep 29 2011
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| 6 | CISH, SOCS1, SOCS2, SOCS3, SOCS6, SOCS7
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| Increased cytoplasmic levels of CIS, SOCS1, SOCS2, or SOCS3 are required for nuclear translocation.
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| Lee KH, Moon KJ, Kim HS, Yoo BC, Park S, Lee H, Kwon S, Lee ES, Yoon S.
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| FEBS Lett 582(15):2319-24. Epub 2008 Jun 4. 2008
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| 7 | SOCS2
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| Association of single-nucleotide polymorphisms in the suppressor of cytokine signaling 2 (SOCS2) gene with type 2 diabetes in the Japanese.
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| Kato H, Nomura K, Osabe D, Shinohara S, Mizumori O, Katashima R, Iwasaki S, Nishimura K, Yoshino M, Kobori M, Ichiishi E, Nakamura N, Yoshikawa T, Tanahashi T, Keshavarz P, Kunika K, Moritani M, Kudo E, Tsugawa K, Takata Y, Hamada D, Yasui N, Miyamoto T, Shiota H, Inoue H, Itakura M.
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| Genomics 87(4):446-58. Epub 2006 Jan 10. 2006
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| 8 | ELOB, ELOC, SOCS2
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| Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.
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| Bullock AN, Debreczeni JE, Edwards AM, Sundström M, Knapp S.
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| Proc Natl Acad Sci U S A May 16;103(20):7637-42. doi: 10.1073/pnas.0601638103. Epub 2006 May 4 2006
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| 9 | SOCS2
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| SOCS2 negatively regulates growth hormone action in vitro and in vivo.
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| Greenhalgh CJ, Rico-Bautista E, Lorentzon M, Thaus AL, Morgan PO, Willson TA, Zervoudakis P, Metcalf D, Street I, Nicola NA, Nash AD, Fabri LJ, Norstedt G, Ohlsson C, Flores-Morales A, Alexander WS, Hilton DJ.
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| J Clin Invest 115(2):397-406. 2005
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| 10 | SOCS1, SOCS2, SOCS3, SOCS6, SOCS5, SOCS7, SOCS4
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| SOCS1 methylation in patients with newly diagnosed acute myeloid leukemia.
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| Chen CY, Tsay W, Tang JL, Shen HL, Lin SW, Huang SY, Yao M, Chen YC, Shen MC, Wang CH, Tien HF.
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| Genes Chromosomes Cancer 37(3):300-5. 2003
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| 11 | GH1, SOCS2
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| Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2.
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| Leung KC, Doyle N, Ballesteros M, Sjogren K, Watts CK, Low TH, Leong GM, Ross RJ, Ho KK.
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| Proc Natl Acad Sci U S A 100(3):1016-21. Epub 2003 Jan 27. 2003
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| 12 | SOCS1, SOCS2, SOCS3
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| Identification of suppressors of cytokine signaling (SOCS) proteins in human gestational tissues: differential regulation is associated with the onset of labor.
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| Blumenstein M, Bowen-Shauver JM, Keelan JA, Mitchell MD.
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| J Clin Endocrinol Metab 87(3):1094-7. 2002
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| 13 | SOCS2
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| Suppressor of cytokine signaling 2 regulates neuronal differentiation by inhibiting growth hormone signaling.
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| Turnley AM, Faux CH, Rietze RL, Coonan JR, Bartlett PF.
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| Nat Neurosci 5(11):1155-62. 2002
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| 14 | SOCS2
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| Overexpression of SOCS-2 in advanced stages of chronic myeloid leukemia: possible inadequacy of a negative feedback mechanism.
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| Schultheis B, Carapeti-Marootian M, Hochhaus A, Weisser A, Goldman JM, Melo JV.
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| Blood 99(5):1766-75. 2002
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| 15 | SOCS2
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| Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.
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| Greenhalgh CJ, Metcalf D, Thaus AL, Corbin JE, Uren R, Morgan PO, Fabri LJ, Zhang JG, Martin HM, Willson TA, Billestrup N, Nicola NA, Baca M, Alexander WS, Hilton DJ.
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| J Biol Chem 277(43):40181-4. Epub 2002 Sep 02. 2002
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| 16 | SOCS2, SOCS3
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| Suppressor of cytokine signaling (SOCS)-3 protein interacts with the insulin-like growth factor-I receptor.
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| Dey BR, Furlanetto RW, Nissley P.
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| Biochem Biophys Res Commun 278(1):38-43. 2000
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| 17 | SOCS1, SOCS2
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| Radiation hybrid and cytogenetic mapping of SOCS1 and SOCS2 to chromosomes 16p13 and 12q, respectively.
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| Yandava CN, et al.
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| Genomics 61(1):108-11 1999
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| 18 | SOCS1, SOCS2
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| A family of cytokine-inducible inhibitors of signalling.
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| Starr R, et al.
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| Nature 387(6636):917-21 1997
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| 19 | SOCS2, SOCS1, SOCS3
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| Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3.
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| Minamoto S, Ikegame K, Ueno K, Narazaki M, Naka T, Yamamoto H, Matsumoto T, Saito H, Hosoe S, Kishimoto T.
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| Biochem Biophys Res Commun 237(1):79-83. 1997
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