| 1 | SMG6
|
| SMG6 localizes to the chromatoid body and shapes the male germ cell transcriptome to drive spermatogenesis.
|
| Lehtiniemi T, Bourgery M, Ma L, Ahmedani A, Mäkelä M, Asteljoki J, Olotu O, Laasanen S, Zhang FP, Tan K, Chousal JN, Burow D, Koskinen S, Laiho A, Elo LL, Chalmel F, Wilkinson MF, Kotaja N.
|
| Nucleic Acids Res. Nov 11;50(20):11470-11491. doi: 10.1093/nar/gkac900. 2022
|
| 2 | CFTR, SMG6
|
| CFTR mRNAs with nonsense codons are degraded by the SMG6-mediated endonucleolytic decay pathway.
|
| Sanderlin EJ, Keenan MM, Mense M, Revenko AS, Monia BP, Guo S, Huang L.
|
| Nat Commun Apr 29;13(1):2344. doi: 10.1038/s41467-022-29935-9 2022
|
| 3 | DLX1, DLX2, SMG6
|
| Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis.
|
| Guerra GM, May D, Kroll T, Koch P, Groth M, Wang ZQ, Li TL, Grigaravičius P.
|
| Cells. Nov 30;10(12):3365. doi: 10.3390/cells10123365. 2021
|
| 4 | SMG5, SMG6, SMG7
|
| SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity.
|
| Boehm V, Kueckelmann S, Gerbracht JV, Kallabis S, Britto-Borges T, Altmüller J, Krüger M, Dieterich C, Gehring NH.
|
| Nat Commun. Jun 25;12(1):3965. doi: 10.1038/s41467-021-24046-3. 2021
|
| 5 | SMG5, SMG6, SMG7
|
| Dissecting the functions of SMG5, SMG7, and PNRC2 in nonsense-mediated mRNA decay of human cells
|
| Nicholson P, Gkratsou A, Josi C, Colombo M, Mühlemann O.
|
| RNA. Apr;24(4):557-573. doi: 10.1261/rna.063719.117. Epub 2018 Jan 18. 2018
|
| 6 | SMG6, UPF1
|
| A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.
|
| Nicholson P, Josi C, Kurosawa H, Yamashita A, Mühlemann O.
|
| Nucleic Acids Res. Aug;42(14):9217-35. doi: 10.1093/nar/gku645. Epub 2014 Jul 22 2014
|
| 7 | SMG5, SMG6, SMG7, UPF1
|
| Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6
|
| Chakrabarti S, Bonneau F, Schüssler S, Eppinger E, Conti E
|
| Nucleic Acids Res. Aug;42(14):9447-60. doi: 10.1093/nar/gku578. Epub 2014 Jul 10. 2014
|
| 8 | SMG5, SMG6, SMG7, UPF1
|
| Autoregulation of the nonsense-mediated mRNA decay pathway in human cells.
|
| Yepiskoposyan H, Aeschimann F, Nilsson D, Okoniewski M, Mühlemann O.
|
| RNA. Dec;17(12):2108-18. doi: 10.1261/rna.030247.111. Epub 2011 Oct 25. 2011
|
| 9 | SMG6
|
| SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay.
|
| Kashima I, Jonas S, Jayachandran U, Buchwald G, Conti E, Lupas AN, Izaurralde E.
|
| Genes Dev 24(21):2440-50. Epub 2010 Oct 7.
2010
|
| 10 | SMG6
|
| SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells.
|
| Eberle AB, Lykke-Andersen S, Mühlemann O, Jensen TH.
|
| Nat Struct Mol Biol 16(1):49-55. Epub 2008 Dec 7.
2009
|
| 11 | SMG6
|
| Protein RNA and protein protein interactions mediate association of human EST1A/SMG6 with telomerase.
|
| Redon S, Reichenbach P, Lingner J.
|
| Nucleic Acids Res 35(20):7011-22. Epub 2007 Oct 16.
2007
|
| 12 | SMG6
|
| Crystal structure of the PIN domain of human telomerase-associated protein EST1A.
|
| Takeshita D, Zenno S, Lee WC, Saigo K, Tanokura M.
|
| Proteins 68(4):980-9.
2007
|
| 13 | SMG6
|
| Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
|
| Azzalin CM, Reichenbach P, Khoriauli L, Giulotto E, Lingner J.
|
| Science 318(5851):798-801. Epub 2007 Oct 4.
2007
|
| 14 | SMG5, SMG6
|
| Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
|
| Glavan F, Behm-Ansmant I, Izaurralde E, Conti E.
|
| EMBO J 25(21):5117-25. Epub 2006 Oct 19. 2006
|
| 15 | SMG6
|
| Crystallization and preliminary X-ray analysis of the PIN domain of human EST1A.
|
| Takeshita D, Zenno S, Lee WC, Saigo K, Tanokura M.
|
| Acta Crystallogr Sect F Struct Biol Cryst Commun 62(Pt 7):656-8. Epub 2006 Jun 10.
2006
|