| 1 | SMAD1, SMAD5, SMAD9, TGFB1i1
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| Hic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8.
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| Shola DT, Wang H, Wahdan-Alaswad R, Danielpour D.
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| Oncogene 31(19):2480-90. doi: 10.1038/onc.2011.422. Epub 2011 Sep 26.
2012
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| 2 | BMP6, CREBZF, SMAD1, SMAD5, SMAD9
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| CREBZF, a novel Smad8-binding protein.
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| Lee JH, Lee GT, Kwon SJ, Jeong J, Ha YS, Kim WJ, Kim IY.
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| Mol Cell Biochem 368(1-2):147-53. doi: 10.1007/s11010-012-1353-4. Epub 2012 Jun 16.
2012
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| 3 | DEL5Q31, PITX1, SMAD5, WNT8A
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| Deletions and duplications of developmental pathway genes in 5q31 contribute to abnormal phenotypes.
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| Rosenfeld JA, Drautz JM, Clericuzio CL, Cushing T, Raskin S, Martin J, Tervo RC, Pitarque JA, Nowak DM, Karolak JA, Lamb AN, Schultz RA, Ballif BC, Bejjani BA, Gajecka M, Shaffer LG.
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| Am J Med Genet A 155A(8):1906-16. doi: 10.1002/ajmg.a.34100. Epub 2011 Jul 8. 2011
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| 4 | PARP1, SMAD1, SMAD2, SMAD3, SMAD4, SMAD5, SMAD6
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| PARP-1 attenuates Smad-mediated transcription.
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| Lönn P, van der Heide LP, Dahl M, Hellman U, Heldin CH, Moustakas A.
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| Mol Cell 40(4):521-32.
2010
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| 5 | ACVR1, FOP, SMAD1, SMAD5
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| Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva.
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| Fukuda T, Kohda M, Kanomata K, Nojima J, Nakamura A, Kamizono J, Noguchi Y, Iwakiri K, Kondo T, Kurose J, Endo K, Awakura T, Fukushi J, Nakashima Y, Chiyonobu T, Kawara A, Nishida Y, Wada I, Akita M, Komori T, Nakayama K, Nanba A, Maruki Y, Yoda T, Tomoda H, Yu PB, Shore EM, Kaplan FS, Miyazono K, Matsuoka M, Ikebuchi K, Ohtake A, Oda H, Jimi E, Owan I, Okazaki Y, Katagiri T.
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| J Biol Chem 284(11):7149-56. Epub 2008 Aug 6.
2009
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| 6 | SMAD1, SMAD5, SMAD9
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| Serotonin induces Rho/ROCK-dependent activation of Smads 1/5/8 in pulmonary artery smooth muscle cells.
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| Liu Y, Ren W, Warburton R, Toksoz D, Fanburg BL.
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| FASEB J 23(7):2299-306. Epub 2009 Feb 25. 2009
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| 7 | SMAD5
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| Smad5 haploinsufficiency leads to hair cell and hearing loss.
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| Yang SM, Guo WW, Hu YY, Sun YX, Hou ZH, Sun JH, Wang X, He DZ, Zhai SQ, Young WY, Han DY, Yang X.
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| Dev Neurobiol 69(2-3):153-61.
2009
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| 8 | BMP4, SMAD5
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| BMP4/Smad5 dependent stress erythropoiesis is required for the expansion of erythroid progenitors during fetal development.
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| Porayette P, Paulson RF.
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| Dev Biol 317(1):24-35. Epub 2008 Feb 15.
2008
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| 9 | SMAD1, SMAD4, SMAD5, SMAD6, SMAD7, SMAD9
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| SMAD expression in the testis: an insight into BMP regulation of spermatogenesis.
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| Itman C, Loveland KL.
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| Dev Dyn 237(1):97-111.PMID: 18069690 2008
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| 10 | SMAD1, SMAD2, SMAD3, SMAD4, SMAD5
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| Bone morphogenetic protein 2 stimulation of tumor growth involves the activation of Smad-1/5.
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| Langenfeld EM, Kong Y, Langenfeld J.
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| Oncogene 25(5):685-92.
2006
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| 11 | SMAD5, SUV39H2
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| Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression.
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| Frontelo P, Leader JE, Yoo N, Potocki AC, Crawford M, Kulik M, Lechleider RJ.
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| Oncogene 23(30):5242-51.
2004
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| 12 | SMAD5
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| Mitochondrial localization of Smad5 in a human chondrogenic cell line.
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| Jullig M, Stott NS.
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| Biochem Biophys Res Commun 307(1):108-13. 2003
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| 13 | SMAD5OS, SMAD5
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| An antisense transcript to SMAD5 expressed in fetal and tumor tissues.
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| Zavadil J, Svoboda P, Liang H, Kottickal LV, Nagarajan L.
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| Biochem Biophys Res Commun 255(3):668-72. 1999
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| 14 | SMAD5
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| hSmad5 gene, a human hSmad family member : its full length cDNA, genomic structure, promoter region and mutation analysis in human tumors.
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| Gemma A, Hagiwara K, Vincent F, Ke Y, Hancock AR, Nagashima M, Bennett WP, Harris CC.
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| Oncogene 16(7):951-6. 1998
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| 15 | SMAD1, SMAD2, SMAD3, SMAD4, SMAD5, SMAD6
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| Frequency of Smad gene mutations in human cancers.
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| Riggins GJ, Kinzler KW, Vogelstein B, Thiagalingam S.
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| Cancer Res 57(13):2578-80. 1997
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| 16 | SMAD5, TSG5D
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| Smad5, a tumor suppressor candidate at 5q31.1, is hemizygously lost and not mutated in the retained allele in human leukemia cell line HL60.
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| Zavadil J, Brezinova J, Svoboda P, Zemanova Z, Michalova K.
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| Leukemia 11(8):1187-92. 1997
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| 17 | SMAD5
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| Localization of SMAD5 and its evaluation as a candidate myeloid tumor suppressor.
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| Hejlik DP, Kottickal LV, Liang H, Fairman J, Davis T, Janecki T, Sexton D, Perry W 3rd, Tavtigian SV, Teng DH, Nagarajan L.
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| Cancer Res 57(17):3779-83. 1997
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| 18 | SMAD1, SMAD5, SMAD3, SMAD6, SMAD2
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| Mad-related genes in the human.
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| Riggins GJ, et al.
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| Nat Genet 13 : 347-349. 1996
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| 19 | SMAD5
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| MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling.
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| Macias-Silva M, et al.
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| Cell 87 : 1215-1224. 1996
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