| 1 | ROBO1, ROBO2, SLIT1, SLIT2, SLIT3
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| Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion.
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| Yang YH, Manning Fox JE, Zhang KL, MacDonald PE, Johnson JD.
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| Proc Natl Acad Sci U S A 110(41):16480-5. doi: 10.1073/pnas.1214312110. Epub 2013 Sep 24.
2013
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| 2 | SLIT1, SLIT2, SLIT3
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| The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis.
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| Guijarro-Muņoz I, Cuesta AM, Alvarez-Cienfuegos A, Geng JG, Alvarez-Vallina L, Sanz L.
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| Exp Cell Res 318(4):371-8. doi: 10.1016/j.yexcr.2011.12.005. Epub 2011 Dec 14.
2012
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| 3 | DCC, EPHB1, NTNG1, SEMA5A, SLIT3
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| Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics.
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| Lin L, Lesnick TG, Maraganore DM, Isacson O.
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| Trends Neurosci 32(3):142-9. Epub 2009 Jan 21. Review.PMID: 19162339 2009
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| 4 | SLIT3
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| Repulsive axon guidance molecule Slit3 is a novel angiogenic factor.
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| Zhang B, Dietrich UM, Geng JG, Bicknell R, Esko JD, Wang L.
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| Blood 114(19):4300-9. Epub 2009 Sep 9.PMID: 19741192 2009
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| 5 | ROBO1, ROBO2, SLIT2, SLIT3
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| Novel regulated expression of the SLIT/ROBO pathway in the ovary: possible role during luteolysis in women.
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| Dickinson RE, Myers M, Duncan WC.
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| Endocrinology 149(10):5024-34. Epub 2008 Jun 19.PMID: 18566128 2008
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| 6 | SLIT3
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| Slit3 regulates cell motility through Rac/Cdc42 activation in lipopolysaccharide-stimulated macrophages.
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| Tanno T, Fujiwara A, Sakaguchi K, Tanaka K, Takenaka S, Tsuyama S.
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| FEBS Lett 581(5):1022-6. Epub 2007 Feb 12.PMID: 17306799 2007
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| 7 | SLIT1, SLIT2, SLIT3
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| Comparative genomics on SLIT1, SLIT2, and SLIT3 orthologs.
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| Katoh Y, Katoh M.
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| Oncol Rep 14(5):1351-5.PMID: 16211308 2005
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| 8 | ROBO1, ROBO2, SLIT3
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| Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding.
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| Liu Z, Patel K, Schmidt H, Andrews W, Pini A, Sundaresan V.
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| Mol Cell Neurosci 26(2):232-40.PMID: 15207848 2004
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| 9 | ROBO1, ROBO2, ROBO3, SLIT1, SLIT2, SLIT3
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| Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain.
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| Bagri A, Marin O, Plump AS, Mak J, Pleasure SJ, Rubenstein JL, Tessier-Lavigne M.
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| Neuron 33(2):233-48. 2002
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| 10 | SLIT1, SLIT2, SLIT3
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| The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors.
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| Wu JY, Feng L, Park HT, Havlioglu N, Wen L, Tang H, Bacon KB, Jiang Zh, Zhang Xc, Rao Y.
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| Nature 410(6831):948-52. 2001
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| 11 | SLIT1, SLIT2, SLIT3
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| Dual trafficking of Slit3 to mitochondria and cell surface demonstrates novel localization for Slit protein.
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| Little MH, Wilkinson L, Brown DL, Piper M, Yamada T, Stow JL.
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| Am J Physiol Cell Physiol 281(2):C486-95.PMID: 11443047 2001
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| 12 | SLIT1, SLIT3, GPC1
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| Mammalian homologues of the Drosophila slit protein are ligands of the heparan sulfate proteoglycan glypican-1 in brain.
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| Liang Y, et al.
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| J Biol Chem 274(25):17885-92. 1999
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| 13 | SLIT2, SLIT1, SLIT2, SLIT3
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| Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching.
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| Wang KH, Brose K, Arnott D, Kidd T, Goodman CS, Henzel W, Tessier-Lavigne M.
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| Cell 96(6):771-84. 1999
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| 14 | SLIT1, SLIT2, SLIT3
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| Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons.
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| Li HS, Chen JH, Wu W, Fagaly T, Zhou L, Yuan W, Dupuis S, Jiang ZH, Nash W, Gick C, Ornitz DM, Wu JY, Rao Y.
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| Cell 96(6):807-18. 1999
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| 15 | ROBO1, ROBO2, ROBO3, SLIT1, SLIT2, SLIT3
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| Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
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| Brose K, Bland KS, Wang KH, Arnott D, Henzel W, Goodman CS, Tessier-Lavigne M, Kidd T.
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| Cell 96(6):795-806. 1999
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| 16 | SLIT1, SLIT2, SLIT3
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| Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.
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| Itoh A, et al.
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| Brain Res Mol Brain Res 62(2):175-86 1998
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| 17 | FAT2, CELSR3, CELSR2, MEGF6, MEGF8, MEGF9, LRP4, SLIT1, SLIT3
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| Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.
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| Nakayama M, Nakajima D, Nagase T, Nomura N, Seki N, Ohara O.
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| Genomics 51(1):27-34. 1998
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