Citations for
1SCARB1, SLC9A3R1, SLC9A3R2
NHERF1 and NHERF2 regulation of SR-B1 stability via ubiquitination and proteasome degradation.
Lu X, He L, Zhou Q, Wang M, Shen WJ, Azhar S, Pan F, Guo Z, Hu Z.
Biochem Biophys Res Commun 490(4):1168-1175. doi: 10.1016/j.bbrc.2017.06.175. Epub 2017 Jun 29. 2017
2SLC9A3R2
SIP1/NHERF2 enhances estrogen receptor alpha transactivation in breast cancer cells.
Meneses-Morales I, Tecalco-Cruz AC, Barrios-García T, Gómez-Romero V, Trujillo-González I, Reyes-Carmona S, García-Zepeda E, Méndez-Enríquez E, Cervantes-Roldán R, Pérez-Sánchez V, Recillas-Targa F, Mohar-Betancourt A, León-Del-Río A.
Nucleic Acids Res 42(11):6885-900. doi: 10.1093/nar/gku311. Epub 2014 Apr 25. 2014
3LPAR2, SLC9A3R2
Structural insights into PDZ-mediated interaction of NHERF2 and LPA(2), a cellular event implicated in CFTR channel regulation.
Holcomb J, Jiang Y, Lu G, Trescott L, Brunzelle J, Sirinupong N, Li C, Naren AP, Yang Z.
Biochem Biophys Res Commun 446(1):399-403. doi: 10.1016/j.bbrc.2014.02.128. Epub 2014 Mar 12. 2014
4SCARB1, SLC9A3R1, SLC9A3R2
Regulation of expression and function of scavenger receptor class B, type I (SR-BI) by Na+/H+ exchanger regulatory factors (NHERFs).
Hu Z, Hu J, Zhang Z, Shen WJ, Yun CC, Berlot CH, Kraemer FB, Azhar S.
J Biol Chem 288(16):11416-35. doi: 10.1074/jbc.M112.437368. Epub 2013 Mar 12. 2013
5SLC9A3R2
NHERF2 is crucial in ERM phosphorylation in pulmonary endothelial cells.
Boratkó A, Csortos C.
Cell Commun Signal 11:99. doi: 10.1186/1478-811X-11-99. 2013
6SLC9A3R2
NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells.
Yang J, Singh V, Cha B, Chen TE, Sarker R, Murtazina R, Jin S, Zachos NC, Patterson GH, Tse CM, Kovbasnjuk O, Li X, Donowitz M.
J Biol Chem 288(23):16960-74. doi: 10.1074/jbc.M113.470799. Epub 2013 Apr 23. 2013
7SLC1A3, SLC9A3R1, SLC9A3R2
Modulatory roles of NHERF1 and NHERF2 in cell surface expression of the glutamate transporter GLAST.
Sato K, Otsu W, Otsuka Y, Inaba M.
Biochem Biophys Res Commun 430(2):839-45. doi: 10.1016/j.bbrc.2012.11.059. Epub 2012 Nov 27. 2013
8SLC9A3R2
NHERF-2 maintains endothelial homeostasis.
Bhattacharya R, Wang E, Dutta SK, Vohra PK, E G, Prakash YS, Mukhopadhyay D.
Blood 119(20):4798-806. doi: 10.1182/blood-2011-11-392563. Epub 2012 Feb 17. 2012
9C3AR1, SLC9A3R1, SLC9A3R2
Roles for NHERF1 and NHERF2 on the regulation of C3a receptor signaling in human mast cells.
Subramanian H, Gupta K, Ali H.
PLoS One 7(12):e51355. doi: 10.1371/journal.pone.0051355. Epub 2012 Dec 20. 2012
10SLC9A3R2, TRPV5, WNK4
Concerted actions of NHERF2 and WNK4 in regulating TRPV5.
Jing H, Na T, Zhang W, Wu G, Liu C, Peng JB.
Biochem Biophys Res Commun 404(4):979-84. Epub 2010 Dec 25. 2011
11SLC9A3, SLC9A3R1, SLC9A3R2
NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity.
Sarker R, Valkhoff VE, Zachos NC, Lin R, Cha B, Chen TE, Guggino S, Zizak M, de Jonge H, Hogema B, Donowitz M.
Am J Physiol Cell Physiol 300(4):C771-82. doi: 10.1152/ajpcell.00119.2010. Epub 2010 Dec 29. 2011
12MAGI3, SLC9A3R2
MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells.
Lee SJ, Ritter SL, Zhang H, Shim H, Hall RA, Yun CC.
Gastroenterology 140(3):924-34. doi: 10.1053/j.gastro.2010.11.054. Epub 2010 Dec 4. 2011
13GRM5, SLC9A3R2
The scaffold protein NHERF2 determines the coupling of P2Y1 nucleotide and mGluR5 glutamate receptor to different ion channels in neurons.
Filippov AK, Simon J, Barnard EA, Brown DA.
J Neurosci 30(33):11068-72.PMID: 20720114 2010
14ATP2B2, SLC9A3R2
Apical scaffolding protein NHERF2 modulates the localization of alternatively spliced plasma membrane Ca2+ pump 2B variants in polarized epithelial cells.
Padányi R, Xiong Y, Antalffy G, Lór K, Pászty K, Strehler EE, Enyedi A.
J Biol Chem 285(41):31704-12. Epub 2010 Jul 27. 2010
15MCC, SCRIB, SLC9A3R1, SLC9A3R2
MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells.
Arnaud C, Sebbagh M, Nola S, Audebert S, Bidaut G, Hermant A, Gayet O, Dusetti NJ, Ollendorff V, Santoni MJ, Borg JP, Lécine P.
FEBS Lett 583(14):2326-32. Epub 2009 Jun 24. 2009
16PRKD1, PRKD2, SLC9A3R1, SLC9A3R2
The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity.
Kunkel MT, Garcia EL, Kajimoto T, Hall RA, Newton AC.
J Biol Chem 284(36):24653-61. Epub 2009 Jul 6.PMID: 19581308 2009
17CFTR, PDZK1, SLC9A3R1, SLC9A3R2
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.
Singh AK, Riederer B, Krabbenhöft A, Rausch B, Bonhagen J, Lehmann U, de Jonge HR, Donowitz M, Yun C, Weinman EJ, Kocher O, Hogema BM, Seidler U.
J Clin Invest 119(3):540-50. doi: 10.1172/JCI35541. Epub 2009 Feb 16. 2009
18SLC9A3R1, SLC9A3R2
NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility.
Theisen CS, Wahl JK 3rd, Johnson KR, Wheelock MJ.
Mol Biol Cell 18(4):1220-32. Epub 2007 Jan 17. 2007
19GRM5, SLC9A3R2
The PDZ scaffold NHERF-2 interacts with mGluR5 and regulates receptor activity.
Paquet M, Asay MJ, Fam SR, Inuzuka H, Castleberry AM, Oller H, Smith Y, Yun CC, Traynelis SF, Hall RA.
J Biol Chem 281(40):29949-61. Epub 2006 Aug 4. 2006
20PTH1R, SLC9A3R1, SLC9A3R2
Na(+)/H(+ ) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling.
Mahon MJ, Donowitz M, Yun CC, Segre GV.
Nature 417(6891):858-61. 2002
21SLC9A3R1, SLC9A3R2
Oligomerization of NHERF-1 and NHERF-2 PDZ domains: differential regulation by association with receptor carboxyl-termini and by phosphorylation.
Lau AG, Hall RA.
Biochemistry 40(29):8572-80. 2001
22NTHL1, SLC9A3R2, TSC2
Genomic structure and sequence of a human homologue (NTHL1/NTH1) of Escherichia coli endonuclease III with those of the adjacent parts of TSC2 and SLC9A3R2 genes.
Imai K, Sarker AH, Akiyama K, Ikeda S, Yao M, Tsutsui K, Shohmori T, Seki S.
Gene 222(2):287-95. 1998