Citations for
1SLC5A8
Molecular mechanism of SLC5A8 inactivation in breast cancer.
Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M.
Mol Cell Biol 33(19):3920-35. doi: 10.1128/MCB.01702-12. Epub 2013 Aug 5. 2013
2SLC5A8
Gene silencing of SLC5A8 identified by genome-wide methylation profiling in lung cancer.
Park JY, Kim D, Yang M, Park HY, Lee SH, Rincon M, Kreahling J, Plass C, Smiraglia DJ, Tockman MS, Kim SJ.
Lung Cancer 79(3):198-204. doi: 10.1016/j.lungcan.2012.11.019. Epub 2012 Dec 27. 2013
3SLC5A8
The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function.
Coothankandaswamy V, Elangovan S, Singh N, Prasad PD, Thangaraju M, Ganapathy V.
Biochem J 450(1):169-78. doi: 10.1042/BJ20121248. 2013
4SLC5A8
SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma.
Helm J, Coppola D, Ganapathy V, Lloyd M, Centeno BA, Chen DT, Malafa MP, Park JY.
Pancreas 41(6):904-9. doi: 10.1097/MPA.0b013e31823f429f. 2012
5SLC5A8
Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate.
Babu E, Ramachandran S, CoothanKandaswamy V, Elangovan S, Prasad PD, Ganapathy V, Thangaraju M.
Oncogene 30(38):4026-37. doi: 10.1038/onc.2011.113. Epub 2011 Apr 18. 2011
6SLC5A8
Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter.
Miyauchi S, Gopal E, Babu E, Srinivas SR, Kubo Y, Umapathy NS, Thakkar SV, Ganapathy V, Prasad PD.
Biochim Biophys Acta iochim Biophys Acta. 2010 Mar 6. [Epub ahead of print]PMID: 20211600 2010
7SLC5A8
Identification and characterization of the human SLC5A8 gene promoter.
Zhang Y, Bao YL, Wu Y, Yu CL, Sun Y, Li YX.
Cancer Genet Cytogenet 196(2):124-32.PMID: 20082847 2010
8SLC5A8
Anionic leak currents through the Na+/monocarboxylate cotransporter SMCT1.
Coady MJ, Wallendorff B, Bourgeois F, Lapointe JY.
Am J Physiol Cell Physiol 298(1):C124-31. Epub 2009 Oct 28.PMID: 19864324 2010
9SLC5A8
Diclofenac-induced stimulation of SMCT1 (SLC5A8) in a heterologous expression system: a RPE specific phenomenon.
Ananth S, Zhuang L, Gopal E, Itagaki S, Ellappan B, Smith SB, Ganapathy V, Martin P.
Biochem Biophys Res Commun 394(1):75-80. Epub 2010 Feb 21. 2010
10CDX1, CDX2, SLC5A8
CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium.
Kakizaki F, Aoki K, Miyoshi H, Carrasco N, Aoki M, Taketo MM.
Gastroenterology 138(2):627-35. Epub 2009 Nov 10. 2010
11SLC5A12, SLC5A8
Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.
Ganapathy V, Thangaraju M, Gopal E, Martin PM, Itagaki S, Miyauchi S, Prasad PD.
AAPS J 10(1):193-9. Epub 2008 Apr 2. Review.PMID: 18446519 2008
12SLC5A8
Silencing of the candidate tumor suppressor gene solute carrier family 5 member 8 (SLC5A8) in human pancreatic cancer.
Park JY, Helm JF, Zheng W, Ly QP, Hodul PJ, Centeno BA, Malafa MP.
Pancreas 36(4):e32-9.PMID: 18437076 2008
13SLC5A12,SLC5A8
Expression of the Sodium-Coupled Monocarboxylate Transporters SMCT1 (SLC5A8) and SMCT2 (SLC5A12) in Retina.
Martin PM, Dun Y, Mysona B, Ananth S, Roon P, Smith SB, Ganapathy V.
Invest Ophthalmol Vis Sci 48(7):3356-63. 2007
14SLC5A12, SLC5A8
Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney.
Gopal E, Umapathy NS, Martin PM, Ananth S, Gnana-Prakasam JP, Becker H, Wagner CA, Ganapathy V, Prasad PD.
Biochim Biophys Acta [Epub ahead of print] 2007
15SLC5A8
Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract.
Gopal E, Miyauchi S, Martin PM, Ananth S, Roon P, Smith SB, Ganapathy V.
Pharm Res 24(3):575-84. 2007
16SLC5A8
Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT.
Paroder V, Spencer SR, Paroder M, Arango D, Schwartz S Jr, Mariadason JM, Augenlicht LH, Eskandari S, Carrasco N.
Proc Natl Acad Sci U S A 103(19):7270-5. Epub 2006 May 2. 2006
17SLC5A8, BRAF
Silencing of the tumor suppressor gene SLC5A8 is associated with BRAF mutations in classical papillary thyroid carcinomas.
Porra V, Ferraro-Peyret C, Durand C, Selmi-Ruby S, Giroud H, Berger-Dutrieux N, Decaussin M, Peix JL, Bournaud C, Orgiazzi J, Borson-Chazot F, Dante R, Rousset B.
J Clin Endocrinol Metab 90(5):3028-35. Epub 2005 Feb 1. 2005
18SLC5A12, SLC5A8
Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2).
Srinivas SR, Gopal E, Zhuang L, Itagaki S, Martin PM, Fei YJ, Ganapathy V, Prasad PD.
Biochem J 392(Pt 3):655-64. 2005
19SLC5A8
SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers.
Li H, Myeroff L, Smiraglia D, Romero MF, Pretlow TP, Kasturi L, Lutterbaugh J, Rerko RM, Casey G, Issa JP, Willis J, Willson JK, Plass C, Markowitz SD.
Proc Natl Acad Sci U S A 100(14):8412-7. Epub 2003 Jun 26. 2003
20SLC5A8
Identification and characterization of a putative human iodide transporter located at the apical membrane of thyrocytes.
Rodriguez AM, Perron B, Lacroix L, Caillou B, Leblanc G, Schlumberger M, Bidart JM, Pourcher T.
J Clin Endocrinol Metab 87(7):3500-3. 2002