1 | SLC5A8
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| Molecular mechanism of SLC5A8 inactivation in breast cancer.
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| Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M.
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| Mol Cell Biol 33(19):3920-35. doi: 10.1128/MCB.01702-12. Epub 2013 Aug 5.
2013
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2 | SLC5A8
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| Gene silencing of SLC5A8 identified by genome-wide methylation profiling in lung cancer.
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| Park JY, Kim D, Yang M, Park HY, Lee SH, Rincon M, Kreahling J, Plass C, Smiraglia DJ, Tockman MS, Kim SJ.
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| Lung Cancer 79(3):198-204. doi: 10.1016/j.lungcan.2012.11.019. Epub 2012 Dec 27.
2013
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3 | SLC5A8
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| The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function.
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| Coothankandaswamy V, Elangovan S, Singh N, Prasad PD, Thangaraju M, Ganapathy V.
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| Biochem J 450(1):169-78. doi: 10.1042/BJ20121248.
2013
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4 | SLC5A8
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| SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma.
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| Helm J, Coppola D, Ganapathy V, Lloyd M, Centeno BA, Chen DT, Malafa MP, Park JY.
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| Pancreas 41(6):904-9. doi: 10.1097/MPA.0b013e31823f429f.
2012
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5 | SLC5A8
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| Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate.
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| Babu E, Ramachandran S, CoothanKandaswamy V, Elangovan S, Prasad PD, Ganapathy V, Thangaraju M.
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| Oncogene 30(38):4026-37. doi: 10.1038/onc.2011.113. Epub 2011 Apr 18.
2011
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6 | SLC5A8
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| Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter.
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| Miyauchi S, Gopal E, Babu E, Srinivas SR, Kubo Y, Umapathy NS, Thakkar SV, Ganapathy V, Prasad PD.
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| Biochim Biophys Acta iochim Biophys Acta. 2010 Mar 6. [Epub ahead of print]PMID: 20211600 2010
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7 | SLC5A8
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| Identification and characterization of the human SLC5A8 gene promoter.
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| Zhang Y, Bao YL, Wu Y, Yu CL, Sun Y, Li YX.
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| Cancer Genet Cytogenet 196(2):124-32.PMID: 20082847 2010
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8 | SLC5A8
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| Anionic leak currents through the Na+/monocarboxylate cotransporter SMCT1.
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| Coady MJ, Wallendorff B, Bourgeois F, Lapointe JY.
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| Am J Physiol Cell Physiol 298(1):C124-31. Epub 2009 Oct 28.PMID: 19864324 2010
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9 | SLC5A8
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| Diclofenac-induced stimulation of SMCT1 (SLC5A8) in a heterologous expression system: a RPE specific phenomenon.
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| Ananth S, Zhuang L, Gopal E, Itagaki S, Ellappan B, Smith SB, Ganapathy V, Martin P.
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| Biochem Biophys Res Commun 394(1):75-80. Epub 2010 Feb 21.
2010
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10 | CDX1, CDX2, SLC5A8
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| CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium.
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| Kakizaki F, Aoki K, Miyoshi H, Carrasco N, Aoki M, Taketo MM.
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| Gastroenterology 138(2):627-35. Epub 2009 Nov 10.
2010
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11 | SLC5A12, SLC5A8
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| Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.
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| Ganapathy V, Thangaraju M, Gopal E, Martin PM, Itagaki S, Miyauchi S, Prasad PD.
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| AAPS J 10(1):193-9. Epub 2008 Apr 2. Review.PMID: 18446519 2008
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12 | SLC5A8
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| Silencing of the candidate tumor suppressor gene solute carrier family 5 member 8 (SLC5A8) in human pancreatic cancer.
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| Park JY, Helm JF, Zheng W, Ly QP, Hodul PJ, Centeno BA, Malafa MP.
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| Pancreas 36(4):e32-9.PMID: 18437076 2008
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13 | SLC5A12,SLC5A8
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| Expression of the Sodium-Coupled Monocarboxylate Transporters SMCT1 (SLC5A8) and SMCT2 (SLC5A12) in Retina.
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| Martin PM, Dun Y, Mysona B, Ananth S, Roon P, Smith SB, Ganapathy V.
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| Invest Ophthalmol Vis Sci 48(7):3356-63. 2007
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14 | SLC5A12, SLC5A8
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| Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney.
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| Gopal E, Umapathy NS, Martin PM, Ananth S, Gnana-Prakasam JP, Becker H, Wagner CA, Ganapathy V, Prasad PD.
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| Biochim Biophys Acta [Epub ahead of print] 2007
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15 | SLC5A8
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| Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract.
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| Gopal E, Miyauchi S, Martin PM, Ananth S, Roon P, Smith SB, Ganapathy V.
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| Pharm Res 24(3):575-84. 2007
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16 | SLC5A8
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| Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT.
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| Paroder V, Spencer SR, Paroder M, Arango D, Schwartz S Jr, Mariadason JM, Augenlicht LH, Eskandari S, Carrasco N.
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| Proc Natl Acad Sci U S A 103(19):7270-5. Epub 2006 May 2. 2006
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17 | SLC5A8, BRAF
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| Silencing of the tumor suppressor gene SLC5A8 is associated with BRAF mutations in classical papillary thyroid carcinomas.
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| Porra V, Ferraro-Peyret C, Durand C, Selmi-Ruby S, Giroud H, Berger-Dutrieux N, Decaussin M, Peix JL, Bournaud C, Orgiazzi J, Borson-Chazot F, Dante R, Rousset B.
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| J Clin Endocrinol Metab 90(5):3028-35. Epub 2005 Feb 1. 2005
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18 | SLC5A12, SLC5A8
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| Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2).
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| Srinivas SR, Gopal E, Zhuang L, Itagaki S, Martin PM, Fei YJ, Ganapathy V, Prasad PD.
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| Biochem J 392(Pt 3):655-64. 2005
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19 | SLC5A8
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| SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers.
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| Li H, Myeroff L, Smiraglia D, Romero MF, Pretlow TP, Kasturi L, Lutterbaugh J, Rerko RM, Casey G, Issa JP, Willis J, Willson JK, Plass C, Markowitz SD.
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| Proc Natl Acad Sci U S A 100(14):8412-7. Epub 2003 Jun 26. 2003
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20 | SLC5A8
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| Identification and characterization of a putative human iodide transporter located at the apical membrane of thyrocytes.
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| Rodriguez AM, Perron B, Lacroix L, Caillou B, Leblanc G, Schlumberger M, Bidart JM, Pourcher T.
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| J Clin Endocrinol Metab 87(7):3500-3. 2002
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