| 1 | CD99, SLC3A2
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| CD99 inhibits CD98-mediated β1 integrin signaling through SHP2-mediated FAK dephosphorylation.
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| Lee KJ, Yoo YH, Kim MS, Yadav BK, Kim Y, Lim D, Hwangbo C, Moon KW, Kim D, Jeoung D, Lee H, Lee JH, Hahn JH.
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| Exp Cell Res 336(2):211-22. doi: 10.1016/j.yexcr.2015.07.010. Epub 2015 Jul 11.
2015
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| 2 | SLC3A2
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| Herpes Simplex Virus 1 Recruits CD98 Heavy Chain and β1 Integrin to the Nuclear Membrane for Viral De-Envelopment.
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| Hirohata Y, Arii J, Liu Z, Shindo K, Oyama M, Kozuka-Hata H, Sagara H, Kato A, Kawaguchi Y.
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| J Virol 89(15):7799-812. doi: 10.1128/JVI.00741-15. Epub 2015 May 20.
2015
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| 3 | NCAPD3, SLC3A2, SLC5A7
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| Chromosome-associated protein D3 promotes bacterial clearance in human intestinal epithelial cells by repressing expression of amino acid transporters.
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| Schuster AT, Homer CR, Kemp JR, Nickerson KP, Deutschman E, Kim Y, West G, Sadler T, Stylianou E, Krokowski D, Hatzoglou M, de la Motte C, Rubin BP, Fiocchi C, McDonald C, Longworth MS.
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| Gastroenterology 148(7):1405-1416.e3. doi: 10.1053/j.gastro.2015.02.013. Epub 2015 Feb 18.
2015
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| 4 | SLC3A2
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| CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction.
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| Estrach S, Lee SA, Boulter E, Pisano S, Errante A, Tissot FS, Cailleteau L, Pons C, Ginsberg MH, Féral CC.
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| Cancer Res 74(23):6878-89. doi: 10.1158/0008-5472.CAN-14-0579. Epub 2014 Sep 29.
2014
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| 5 | BSG, SLC3A2
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| CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway.
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| Fei F, Li X, Xu L, Li D, Zhang Z, Guo X, Yang H, Chen Z, Xing J.
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| Ann Surg Oncol 21(13):4359-68. doi: 10.1245/s10434-014-3816-1. Epub 2014 Aug 2.
2014
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| 6 | SLC3A2
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| CD98hc regulates the development of experimental colitis by controlling effector and regulatory CD4(+) T cells.
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| Bhuyan ZA, Arimochi H, Nishida J, Kataoka K, Kurihara T, Ishifune C, Tsumura H, Ito M, Ito Y, Kitamura A, Yasutomo K.
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| Biochem Biophys Res Commun 444(4):628-33. doi: 10.1016/j.bbrc.2014.01.144. Epub 2014 Jan 31.
2014
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| 7 | RHOA, SLC3A2
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| CD98hc (SLC3A2) regulation of skin homeostasis wanes with age.
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| Boulter E, Estrach S, Errante A, Pons C, Cailleteau L, Tissot F, Meneguzzi G, Féral CC.
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| J Exp Med 210(1):173-90. doi: 10.1084/jem.20121651. Epub 2013 Jan 7.
2013
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| 8 | SLC3A2
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| The role of CD98hc in mouse macrophage functions.
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| Tsumura H, Ito M, Li XK, Nakamura A, Ohnami N, Fujimoto J, Komada H, Ito Y.
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| Cell Immunol 276(1-2):128-34. doi: 10.1016/j.cellimm.2012.04.012. Epub 2012 May 7.
2012
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| 9 | MARCHF8, SLC3A2
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| MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation.
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| Eyster CA, Cole NB, Petersen S, Viswanathan K, Früh K, Donaldson JG.
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| Mol Biol Cell 22(17):3218-30. Epub 2011 Jul 14. 2011
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| 10 | SLC3A2
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| CD98hc (SLC3A2) is a key regulator of keratinocyte adhesion.
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| Lemaître G, Stella A, Feteira J, Baldeschi C, Vaigot P, Martin MT, Monsarrat B, Waksman G.
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| J Dermatol Sci 61(3):169-79. doi: 10.1016/j.jdermsci.2010.12.007. Epub 2011 Jan 11.
2011
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| 11 | SLC3A2
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| Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2).
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| Fogelstrand P, Féral CC, Zargham R, Ginsberg MH.
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| J Exp Med 206(11):2397-406. doi: 10.1084/jem.20082845. Epub 2009 Oct 19.
2009
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| 12 | SAT1, SLC3A2
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| Identification and characterization of a diamine exporter in colon epithelial cells.
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| Uemura T, Yerushalmi HF, Tsaprailis G, Stringer DE, Pastorian KE, Hawel L 3rd, Byus CV, Gerner EW.
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| J Biol Chem 283(39):26428-35. Epub 2008 Jul 25.
2008
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| 13 | SLC3A2
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| Ecto-phosphorylation of CD98 regulates cell-cell interactions.
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| Nguyen HT, Dalmasso G, Yan Y, Obertone TS, Sitaraman SV, Merlin D.
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| PLoS One 3(12):e3895. Epub 2008 Dec 9.
2008
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| 14 | SLC3A2, SLC7A5
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| L-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms.
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| Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, Tanaka S, Ishizuka T, Kanai Y, Endou H, Nakajima T, Mori M.
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| Cancer Sci 99(12):2380-6. Epub 2008 Nov 17.
2008
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| 15 | SLC3A2
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| The membrane-spanning domain of CD98 heavy chain promotes alpha(v)beta3 integrin signals in human extravillous trophoblasts.
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| Kabir-Salmani M, Fukuda MN, Kanai-Azuma M, Ahmed N, Shiokawa S, Akimoto Y, Sakai K, Nagamori S, Kanai Y, Sugihara K, Iwashita M.
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| Mol Endocrinol 22(3):707-15. Epub 2007 Nov 21.
2008
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| 16 | SLC3A2, ITGB1
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| CD98hc (SLC3A2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling.
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| Prager GW, Feral CC, Kim C, Han J, Ginsberg MH.
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| J Biol Chem 282(33):24477-84. Epub 2007 Jun 27. 2007
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| 17 | SLC3A2
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| CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling.
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| Féral CC, Zijlstra A, Tkachenko E, Prager G, Gardel ML, Slepak M, Ginsberg MH.
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| J Cell Biol 178(4):701-11. Epub 2007 Aug 6.
2007
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| 18 | ABCA11P, ABHD6, ABHD8, ACBD4, AKD1, AMER3, ANKRD13B, ANKRD39, ANKRD53, ANKRD55, ANTXRL, ANXA8L2, ARMCX4, ASTN1, BORCS6, BTNL8, C10orf140, C10orf53, C10orf68, C10orf72, C10orf76, C11orf65, C12orf41, C12orf42, C12orf59, C12orf63, C13orf23, C14orf132, C14orf166B, C15orf38, C15orf39, C15orf41, C15orf52, C16orf10, C16orf54, C17orf62, C17orf63, C17orf85, C18orf19, C19orf12, C19orf34, C19orf44, C19orf45, C19orf54, C19orf55, C19orf60, C1orf128, C1orf129, C1orf198, C1orf50, C1orf94, C20orf82, C22orf15, C22orf26, C22orf30, C2CD3, C2orf3, C2orf34, C2orf53, C2orf63, C4orf19, C5orf22, C5orf24, C6orf35, C8orf33, C8orf73, C9orf100, C9orf131, C9orf50, C9orf68, CCDC122, CCDC144C, CCDC146, CCDC40, CCDC71, CCDC77, CCDC96, CCM2L, CD97, CDH6, CEP120, CFAP43, CFAP47, COL11A2, COL9A1, CXorf57, DDTL, DDX60L, DDX60L, DFNB53, DHODH, DNAJB14, DQX1, ECT2L, EFCAB5, ERCC6L2, EXOC3L, FAAH2, FAM110A, FAM136A, FAM153B, FAM160A2, FAM200B, FAM47C, FAM63B, FAM86B1, FASTKD1, FDX1L, FOCAD, FOXRED2, GIN1, GSG1L, HERPUD2, IFITM4P, JMJD7, KCTD4, KIAA1310, KIAA1614, KLHL25, LACC1, LARP4, LRRC27, LRRC31, MACROD2, PCMTD2, RABGGTA, SHOC1, SLC3A2, SLC52A3, SMYD4, TBC1D20, TMEM100, TTI2, ZC3H6, ZNF250, ZNF252, ZNF385B, ZNF491, ZNF493, ZNF506, ZNF517, ZNF525, ZNF529, ZNF568, ZNF611, ZNF614, ZNF616, ZNF621, ZNF624, ZNF627, ZNF630, ZNF721, ZSCAN18, ZSCAN29
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| Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
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| Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S.
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| Genome Res 16(1):55-65. Epub 2005 Dec 12. 2006
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| 19 | HDLBP, TUBA1B, LIPF, MUC8, PDLIM3, PGC, PYCR1, RPS8, SLC3A2, STIP1, TUBA1C, UBC
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| Gene cataloging and expression profiling in human gastric cancer cells by expressed sequence tags.
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| Kim NS, Hahn Y, Oh JH, Lee JY, Oh KJ, Kim JM, Park HS, Kim S, Song KS, Rho SM, Yoo HS, Kim YS.
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| Genomics 83(6):1024-45. 2004
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| 20 | SLC3A2, ITGB1
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| CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation.
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| Henderson NC, Collis EA, Mackinnon AC, Simpson KJ, Haslett C, Zent R, Ginsberg M, Sethi T.
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| J Biol Chem 279(52):54731-41. Epub 2004 Oct 12. 2004
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| 21 | SLC3A2, SLC7A5
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| Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.
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| Yanagida O, Kanai Y, Chairoungdua A, Kim DK, Segawa H, Nii T, Cha SH, Matsuo H, Fukushima J, Fukasawa Y, Tani Y, Taketani Y, Uchino H, Kim JY, Inatomi J, Okayasu I, Miyamoto K, Takeda E, Goya T, Endou H.
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| Biochim Biophys Acta 1514(2):291-302. 2001
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| 22 | SLC7A5, SLC3A2, SLC7A7
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| Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family.
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| Mastroberardino L, Spindler B, Pfeiffer R, Skelly PJ, Loffing J, Shoemaker CB, Verrey F.
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| Nature 395(6699):288-91. 1998
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| 23 | SLC3A2
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| Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98).
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| Kanai Y, Segawa H, Miyamoto Ki, Uchino H, Takeda E, Endou H.
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| J Biol Chem 273(37):23629-32. 1998
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| 24 | ACAN, CD59, FNRBL, ITGA3, MSK10, MSK14, MSK22, MSK24, MSK28, MSK29, MSK33, MSK35, MSK37, MSK38, MSK41, ITGAV, SLC3A2
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| Definition of selectable cell surface markers for human chromosomes and chromosome segments in rodent-human hybrids.
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| Rettig WJ, et al.
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| Somat Cell Mol Genet 14 : 223-231. 1988
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| 25 | SLC3A2
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| Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation.
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| Gottesdiener KM, Karpinski BA, Lindsten T, Strominger JL, Jones NH, Thompson CB, Leiden JM.
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| Mol Cell Biol 8(9):3809-19. 1988
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| 26 | SLC3A2
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| Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth.
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| Quackenbush E, Clabby M, Gottesdiener KM, Barbosa J, Jones NH, Strominger JL, Speck S, Leiden JM.
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| Proc Natl Acad Sci U S A 84(18):6526-30. 1987
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| 27 | SLC3A2
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| Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2.
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| Lumadue JA, Glick AB, Ruddle FH.
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| Proc Natl Acad Sci U S A 84(24):9204-8. 1987
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| 28 | SLC3A2, CD44
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| Chromosome mapping of human cell surface molecules: Monoclonal anti-human lymphocyte antibodies 4F2, A3D8, and A1G3 define antigens controlled by different regions of chromosome 11.
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| Francke U, et al.
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| Somatic Cell Genet 9 : 333-344. 1983
|