Citations for
1CD99, SLC3A2
CD99 inhibits CD98-mediated β1 integrin signaling through SHP2-mediated FAK dephosphorylation.
Lee KJ, Yoo YH, Kim MS, Yadav BK, Kim Y, Lim D, Hwangbo C, Moon KW, Kim D, Jeoung D, Lee H, Lee JH, Hahn JH.
Exp Cell Res 336(2):211-22. doi: 10.1016/j.yexcr.2015.07.010. Epub 2015 Jul 11. 2015
2SLC3A2
Herpes Simplex Virus 1 Recruits CD98 Heavy Chain and β1 Integrin to the Nuclear Membrane for Viral De-Envelopment.
Hirohata Y, Arii J, Liu Z, Shindo K, Oyama M, Kozuka-Hata H, Sagara H, Kato A, Kawaguchi Y.
J Virol 89(15):7799-812. doi: 10.1128/JVI.00741-15. Epub 2015 May 20. 2015
3NCAPD3, SLC3A2, SLC5A7
Chromosome-associated protein D3 promotes bacterial clearance in human intestinal epithelial cells by repressing expression of amino acid transporters.
Schuster AT, Homer CR, Kemp JR, Nickerson KP, Deutschman E, Kim Y, West G, Sadler T, Stylianou E, Krokowski D, Hatzoglou M, de la Motte C, Rubin BP, Fiocchi C, McDonald C, Longworth MS.
Gastroenterology 148(7):1405-1416.e3. doi: 10.1053/j.gastro.2015.02.013. Epub 2015 Feb 18. 2015
4SLC3A2
CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction.
Estrach S, Lee SA, Boulter E, Pisano S, Errante A, Tissot FS, Cailleteau L, Pons C, Ginsberg MH, Féral CC.
Cancer Res 74(23):6878-89. doi: 10.1158/0008-5472.CAN-14-0579. Epub 2014 Sep 29. 2014
5BSG, SLC3A2
CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway.
Fei F, Li X, Xu L, Li D, Zhang Z, Guo X, Yang H, Chen Z, Xing J.
Ann Surg Oncol 21(13):4359-68. doi: 10.1245/s10434-014-3816-1. Epub 2014 Aug 2. 2014
6SLC3A2
CD98hc regulates the development of experimental colitis by controlling effector and regulatory CD4(+) T cells.
Bhuyan ZA, Arimochi H, Nishida J, Kataoka K, Kurihara T, Ishifune C, Tsumura H, Ito M, Ito Y, Kitamura A, Yasutomo K.
Biochem Biophys Res Commun 444(4):628-33. doi: 10.1016/j.bbrc.2014.01.144. Epub 2014 Jan 31. 2014
7RHOA, SLC3A2
CD98hc (SLC3A2) regulation of skin homeostasis wanes with age.
Boulter E, Estrach S, Errante A, Pons C, Cailleteau L, Tissot F, Meneguzzi G, Féral CC.
J Exp Med 210(1):173-90. doi: 10.1084/jem.20121651. Epub 2013 Jan 7. 2013
8SLC3A2
The role of CD98hc in mouse macrophage functions.
Tsumura H, Ito M, Li XK, Nakamura A, Ohnami N, Fujimoto J, Komada H, Ito Y.
Cell Immunol 276(1-2):128-34. doi: 10.1016/j.cellimm.2012.04.012. Epub 2012 May 7. 2012
9MARCH8, SLC3A2
MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation.
Eyster CA, Cole NB, Petersen S, Viswanathan K, Früh K, Donaldson JG.
Mol Biol Cell 22(17):3218-30. Epub 2011 Jul 14. 2011
10SLC3A2
CD98hc (SLC3A2) is a key regulator of keratinocyte adhesion.
Lemaître G, Stella A, Feteira J, Baldeschi C, Vaigot P, Martin MT, Monsarrat B, Waksman G.
J Dermatol Sci 61(3):169-79. doi: 10.1016/j.jdermsci.2010.12.007. Epub 2011 Jan 11. 2011
11SLC3A2
Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2).
Fogelstrand P, Féral CC, Zargham R, Ginsberg MH.
J Exp Med 206(11):2397-406. doi: 10.1084/jem.20082845. Epub 2009 Oct 19. 2009
12SAT1, SLC3A2
Identification and characterization of a diamine exporter in colon epithelial cells.
Uemura T, Yerushalmi HF, Tsaprailis G, Stringer DE, Pastorian KE, Hawel L 3rd, Byus CV, Gerner EW.
J Biol Chem 283(39):26428-35. Epub 2008 Jul 25. 2008
13SLC3A2
Ecto-phosphorylation of CD98 regulates cell-cell interactions.
Nguyen HT, Dalmasso G, Yan Y, Obertone TS, Sitaraman SV, Merlin D.
PLoS One 3(12):e3895. Epub 2008 Dec 9. 2008
14SLC3A2, SLC7A5
L-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms.
Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, Tanaka S, Ishizuka T, Kanai Y, Endou H, Nakajima T, Mori M.
Cancer Sci 99(12):2380-6. Epub 2008 Nov 17. 2008
15SLC3A2
The membrane-spanning domain of CD98 heavy chain promotes alpha(v)beta3 integrin signals in human extravillous trophoblasts.
Kabir-Salmani M, Fukuda MN, Kanai-Azuma M, Ahmed N, Shiokawa S, Akimoto Y, Sakai K, Nagamori S, Kanai Y, Sugihara K, Iwashita M.
Mol Endocrinol 22(3):707-15. Epub 2007 Nov 21. 2008
16SLC3A2, ITGB1
CD98hc (SLC3A2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling.
Prager GW, Feral CC, Kim C, Han J, Ginsberg MH.
J Biol Chem 282(33):24477-84. Epub 2007 Jun 27. 2007
17SLC3A2
CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling.
Féral CC, Zijlstra A, Tkachenko E, Prager G, Gardel ML, Slepak M, Ginsberg MH.
J Cell Biol 178(4):701-11. Epub 2007 Aug 6. 2007
18ABCA11P, ABHD6, ABHD8, ACBD4, AKD1, AMER3, ANKRD13B, ANKRD39, ANKRD53, ANKRD55, ANTXRL, ANXA8L2, ARMCX4, ASTN1, BORCS6, BTNL8, C10orf140, C10orf53, C10orf68, C10orf72, C10orf76, C11orf65, C12orf41, C12orf42, C12orf59, C12orf63, C13orf23, C14orf132, C14orf166B, C15orf38, C15orf39, C15orf41, C15orf52, C16orf10, C16orf54, C17orf62, C17orf63, C17orf85, C18orf19, C19orf12, C19orf34, C19orf44, C19orf45, C19orf54, C19orf55, C19orf60, C1orf128, C1orf129, C1orf198, C1orf50, C1orf94, C20orf82, C22orf15, C22orf26, C22orf30, C2CD3, C2orf3, C2orf34, C2orf53, C2orf63, C4orf19, C5orf22, C5orf24, C6orf35, C8orf33, C8orf73, C9orf100, C9orf131, C9orf50, C9orf68, CCDC122, CCDC144C, CCDC146, CCDC40, CCDC71, CCDC77, CCDC96, CCM2L, CD97, CDH6, CEP120, CFAP43, CFAP47, COL11A2, COL9A1, CXorf57, DDTL, DDX60L, DDX60L, DFNB53, DHODH, DNAJB14, DQX1, ECT2L, EFCAB5, ERCC6L2, EXOC3L, FAAH2, FAM110A, FAM136A, FAM153B, FAM160A2, FAM200B, FAM47C, FAM63B, FAM86B1, FASTKD1, FDX1L, FOCAD, FOXRED2, GIN1, GSG1L, HERPUD2, IFITM4P, JMJD7, KCTD4, KIAA1310, KIAA1614, KLHL25, LACC1, LARP4, LRRC27, LRRC31, MACROD2, PCMTD2, RABGGTA, SHOC1, SLC3A2, SLC52A3, SMYD4, TBC1D20, TMEM100, TTI2, ZC3H6, ZNF250, ZNF252, ZNF385B, ZNF491, ZNF493, ZNF506, ZNF517, ZNF525, ZNF529, ZNF568, ZNF611, ZNF614, ZNF616, ZNF621, ZNF624, ZNF627, ZNF630, ZNF721, ZSCAN18, ZSCAN29
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S.
Genome Res 16(1):55-65. Epub 2005 Dec 12. 2006
19HDLBP, TUBA1B, LIPF, MUC8, PDLIM3, PGC, PYCR1, RPS8, SLC3A2, STIP1, TUBA1C, UBC
Gene cataloging and expression profiling in human gastric cancer cells by expressed sequence tags.
Kim NS, Hahn Y, Oh JH, Lee JY, Oh KJ, Kim JM, Park HS, Kim S, Song KS, Rho SM, Yoo HS, Kim YS.
Genomics 83(6):1024-45. 2004
20SLC3A2, ITGB1
CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation.
Henderson NC, Collis EA, Mackinnon AC, Simpson KJ, Haslett C, Zent R, Ginsberg M, Sethi T.
J Biol Chem 279(52):54731-41. Epub 2004 Oct 12. 2004
21SLC3A2, SLC7A5
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.
Yanagida O, Kanai Y, Chairoungdua A, Kim DK, Segawa H, Nii T, Cha SH, Matsuo H, Fukushima J, Fukasawa Y, Tani Y, Taketani Y, Uchino H, Kim JY, Inatomi J, Okayasu I, Miyamoto K, Takeda E, Goya T, Endou H.
Biochim Biophys Acta 1514(2):291-302. 2001
22SLC7A5, SLC3A2, SLC7A7
Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family.
Mastroberardino L, Spindler B, Pfeiffer R, Skelly PJ, Loffing J, Shoemaker CB, Verrey F.
Nature 395(6699):288-91. 1998
23SLC3A2
Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98).
Kanai Y, Segawa H, Miyamoto Ki, Uchino H, Takeda E, Endou H.
J Biol Chem 273(37):23629-32. 1998
24ACAN, CD59, FNRBL, ITGA3, MSK10, MSK14, MSK22, MSK24, MSK28, MSK29, MSK33, MSK35, MSK37, MSK38, MSK41, ITGAV, SLC3A2
Definition of selectable cell surface markers for human chromosomes and chromosome segments in rodent-human hybrids.
Rettig WJ, et al.
Somat Cell Mol Genet 14 : 223-231. 1988
25SLC3A2
Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation.
Gottesdiener KM, Karpinski BA, Lindsten T, Strominger JL, Jones NH, Thompson CB, Leiden JM.
Mol Cell Biol 8(9):3809-19. 1988
26SLC3A2
Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth.
Quackenbush E, Clabby M, Gottesdiener KM, Barbosa J, Jones NH, Strominger JL, Speck S, Leiden JM.
Proc Natl Acad Sci U S A 84(18):6526-30. 1987
27SLC3A2
Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2.
Lumadue JA, Glick AB, Ruddle FH.
Proc Natl Acad Sci U S A 84(24):9204-8. 1987
28SLC3A2, CD44
Chromosome mapping of human cell surface molecules: Monoclonal anti-human lymphocyte antibodies 4F2, A3D8, and A1G3 define antigens controlled by different regions of chromosome 11.
Francke U, et al.
Somatic Cell Genet 9 : 333-344. 1983