Citations for
Functional disruption of pyrimidine nucleoside transporter CNT1 results in a novel inborn error of metabolism with high excretion of uridine and cytidine.
Wevers RA, Christensen M, Engelke UFH, Geuer S, Coene KLM, Kwast JT, Lund AM, Vissers LELM.
J Inherit Metab Dis 42(3):494-500. doi: 10.1002/jimd.12081. Epub 2019 Apr 8. 2019
A novel RNA variant of human concentrative nucleoside transporter 1 (hCNT1) that is a potential cancer biomarker.
Wang C, Buolamwini JK.
Exp Hematol Oncol 8:18. doi: 10.1186/s40164-019-0144-y. eCollection 2019. 2019
3SLC28A1, SLC28A2, SLC28A3
Expression of Concentrative Nucleoside Transporters ( SLC28A) in the Human Placenta: Effects of Gestation Age and Prototype Differentiation-Affecting Agents.
Jiraskova L, Cerveny L, Karbanova S, Ptackova Z, Staud F.
Mol Pharm 15(7):2732-2741. doi: 10.1021/acs.molpharmaceut.8b00238. Epub 2018 May 25. 2018
Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: overcoming transport defects using a nanoparticle approach.
Hung SW, Marrache S, Cummins S, Bhutia YD, Mody H, Hooks SB, Dhar S, Govindarajan R.
Cancer Lett 359(2):233-40. doi: 10.1016/j.canlet.2015.01.017. Epub 2015 Jan 16. 2015
Concentrative nucleoside transporter 1 (hCNT1) promotes phenotypic changes relevant to tumor biology in a translocation-independent manner.
Pérez-Torras S, Vidal-Pla A, Cano-Soldado P, Huber-Ruano I, Mazo A, Pastor-Anglada M.
Cell Death Dis 4:e648. doi: 10.1038/cddis.2013.173. 2013
Hypoxia and P1 receptor activation regulate the high-affinity concentrative adenosine transporter CNT2 in differentiated neuronal PC12 cells.
Medina-Pulido L, Molina-Arcas M, Justicia C, Soriano E, Burgaya F, Planas AM, Pastor-Anglada M.
Biochem J 454(3):437-45. doi: 10.1042/BJ20130231. 2013
7SLC28A1, SLC28A2, SLC28A3
Functional analysis of the human concentrative nucleoside transporter-1 variant hCNT1S546P provides insight into the sodium-binding pocket.
Cano-Soldado P, Gorraitz E, Errasti-Murugarren E, Casado FJ, Lostao MP, Pastor-Anglada M.
Am J Physiol Cell Physiol 302(1):C257-66. doi: 10.1152/ajpcell.00198.2011. Epub 2011 Oct 12. 2012
CNT1 expression influences proliferation and chemosensitivity in drug-resistant pancreatic cancer cells.
Bhutia YD, Hung SW, Patel B, Lovin D, Govindarajan R.
Cancer Res 71(5):1825-35. doi: 10.1158/0008-5472.CAN-10-2736. Epub 2011 Feb 22. 2011
Hepatocyte nuclear factor-4alpha and bile acids regulate human concentrative nucleoside transporter-1 gene expression.
Klein K, Kullak-Ublick GA, Wagner M, Trauner M, Eloranta JJ.
Am J Physiol Gastrointest Liver Physiol 296(4):G936-47. doi: 10.1152/ajpgi.90678.2008. Epub 2009 Feb 19. 2009
10SLC28A1, SLC29A1
Immunocytochemical detection of hENT1 and hCNT1 in normal tissues, lung cancer cell lines, and NSCLC patient samples.
Hubeek I, Giovannetti E, Broekhuizen AJ, Pastor-Anglada M, Kaspers GJ, Peters GJ.
Nucleosides Nucleotides Nucleic Acids 27(6):787-93.PMID: 18600541 2008
11SLC28A1, SLC28A2, SLC28A3
A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3.
Slugoski MD, Ng AM, Yao SY, Smith KM, Lin CC, Zhang J, Karpinski E, Cass CE, Baldwin SA, Young JD.
J Biol Chem 283(13):8496-507. doi: 10.1074/jbc.M710433200. Epub 2008 Jan 16. 2008
12SLC28A1, SLC28A2
Transcription factors involved in the expression of SLC28 genes in human liver parenchymal cells.
Fernandez-Veledo S, Jover R, Casado FJ, Gomez-Lechon MJ, Pastor-Anglada M.
Biochem Biophys Res Commun 353(2):381-8. Epub 2006 Dec 11. 2007
The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics.
Smith KM, Slugoski MD, Loewen SK, Ng AM, Yao SY, Chen XZ, Karpinski E, Cass CE, Baldwin SA, Young JD.
J Biol Chem 280(27):25436-49. Epub 2005 May 3. 2005
Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations.
Gray JH, Mangravite LM, Owen RP, Urban TJ, Chan W, Carlson EJ, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, Giacomini KM.
Mol Pharmacol 65(3):512-9. 2004
15SLC28A1, SLC29A2
Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors.
FarrŽ X, GuillŽn-G—mez E, S‡nchez L, Hardisson D, Plaza Y, Lloberas J, Casado FJ, Palacios J, Pastor-Anglada M.
Int J Cancer 112(6):959-66. 2004
16SLC28A1, SLC28A2, SLC29A1, SLC29A2
Differential expression of human nucleoside transporters in normal and tumor tissue.
Pennycooke M, Chaudary N, Shuralyova I, Zhang Y, Coe IR.
Biochem Biophys Res Commun 280(3):951-9. 2001
17SLC28A1, SLC29A1
Assignment of the human equilibrative nucleoside transporter (hENT1) to 6p21.1-p21.2.
Coe IR, Griffiths M, Young JD, Baldwin SA, Cass CE.
Genomics 45(2):459-60. 1997
Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1).
Ritzel MW, et al.
Am J Physiol 272 : C707-C714. 1997