1 | SLC1A1, SORCS2
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| SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology.
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| Malik AR, Szydlowska K, Nizinska K, Asaro A, van Vliet EA, Popp O, Dittmar G, Fritsche-Guenther R, Kirwan JA, Nykjaer A, Lukasiuk K, Aronica E, Willnow TE.
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| Cell Rep. Mar 5;26(10):2792-2804.e6. doi: 10.1016/j.celrep.2019.02.027 2019
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2 | CAV1, SLC1A1, SLC1A2, SLC1A3, SLC1A6
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| Caveolin-1 Sensitivity of Excitatory Amino Acid Transporters EAAT1, EAAT2, EAAT3, and EAAT4.
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| Abousaab A, Warsi J, Elvira B, Lang F.
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| J Membr Biol 249(3):239-49. doi: 10.1007/s00232-015-9863-0. Epub 2015 Dec 21.
2016
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3 | OXSR1, SLC1A1, STK39
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| SPAK and OSR1 Sensitivity of Excitatory Amino Acid Transporter EAAT3.
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| Borrás J, Salker MS, Elvira B, Warsi J, Fezai M, Hoseinzadeh Z, Lang F.
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| Nephron 130(3):221-8. doi: 10.1159/000433567. Epub 2015 Jun 25.
2015
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4 | KL, SLC1A1, SLC1A6
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| Klotho sensitivity of the neuronal excitatory amino acid transporters EAAT3 and EAAT4.
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| Almilaji A, Munoz C, Pakladok T, Alesutan I, Feger M, Föller M, Lang UE, Shumilina E, Lang F.
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| PLoS One 8(7):e70988. doi: 10.1371/journal.pone.0070988. Print 2013.
2013
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5 | SLC1A1, SLC8A1
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| Physical and functional interaction of NCX1 and EAAC1 transporters leading to glutamate-enhanced ATP production in brain mitochondria.
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| Magi S, Lariccia V, Castaldo P, Arcangeli S, Nasti AA, Giordano A, Amoroso S.
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| PLoS One 7(3):e34015. doi: 10.1371/journal.pone.0034015. Epub 2012 Mar 30.
2012
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6 | SLC1A1
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| Neutralizing aspartate 83 modifies substrate translocation of excitatory amino acid transporter 3 (EAAT3) glutamate transporters.
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| Hotzy J, Machtens JP, Fahlke C.
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| J Biol Chem 287(24):20016-26. doi: 10.1074/jbc.M112.344077. Epub 2012 Apr 24.
2012
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7 | SLC1A1, SLC1A3, SLC1A6
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| Hetero-oligomerization of neuronal glutamate transporters.
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| Nothmann D, Leinenweber A, Torres-Salazar D, Kovermann P, Hotzy J, Gameiro A, Grewer C, Fahlke C.
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| J Biol Chem 286(5):3935-43. doi: 10.1074/jbc.M110.187492. Epub 2010 Dec 2.
2011
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8 | SLC1A1
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| EAAC1 gene deletion alters zinc homeostasis and exacerbates neuronal injury after transient cerebral ischemia.
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| Won SJ, Yoo BH, Brennan AM, Shin BS, Kauppinen TM, Berman AE, Swanson RA, Suh SW.
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| J Neurosci. 30(46):15409-18. 2010
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9 | SLC1A1
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| A family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder in 378 families.
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| Shugart YY, Wang Y, Samuels JF, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn-Saric R, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle MA, Liang KY, Nestadt G.
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| Am J Med Genet B Neuropsychiatr Genet 150B(6):886-92.PMID: 19152386 2009
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10 | SLC1A1
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| A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder.
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| Wendland JR, Moya PR, Timpano KR, Anavitarte AP, Kruse MR, Wheaton MG, Ren-Patterson RF, Murphy DL.
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| Arch Gen Psychiatry 66(4):408-16.PMID: 19349310 2009
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11 | ARL6IP5, RTN2, SLC1A1
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| Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1.
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| Liu Y, Vidensky S, Ruggiero AM, Maier S, Sitte HH, Rothstein JD.
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| J Biol Chem 283(10):6561-71. Epub 2007 Dec 20. 2008
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12 | ARL6IP1, ARL6IP5, SLC1A1
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| Modulation of the neural glutamate transporter EAAC1 by the addicsin-interacting protein ARL6IP1.
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| Akiduki S, Ikemoto MJ.
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| J Biol Chem 283(46):31323-32. Epub 2008 Aug 6.
2008
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13 | SLC1A1, SLC1A6
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| The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits.
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| Koch HP, Brown RL, Larsson HP.
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| J Neurosci 27(11):2943-7. 2007
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14 | SLC1A1, SLC1A3, SLC1A6
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| Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia.
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| Deng X, Shibata H, Takeuchi N, Rachi S, Sakai M, Ninomiya H, Iwata N, Ozaki N, Fukumaki Y.
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| Am J Med Genet B Neuropsychiatr Genet 144(3):271-8. 2007
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15 | SLC1A1
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| Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder.
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| Stewart SE, Fagerness JA, Platko J, Smoller JW, Scharf JM, Illmann C, Jenike E, Chabane N, Leboyer M, Delorme R, Jenike MA, Pauls DL.
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| Am J Med Genet B Neuropsychiatr Genet 144(8):1027-33. 2007
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16 | CAV1, SLC1A1
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| Caveolin-1 regulates the delivery and endocytosis of the glutamate transporter, excitatory amino acid carrier 1.
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| Gonz‡lez MI, Krizman-Genda E, Robinson MB.
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| J Biol Chem 282(41):29855-65. Epub 2007 Aug 22. 2007
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17 | SLC1A1
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| Regulation of the glutamate transporter EAAC1 by expression and activation of delta-opioid receptor.
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| Xia P, Pei G, Schwarz W.
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| Eur J Neurosci 24(1):87-93. 2006
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18 | SLC1A1
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| Phorbol myristate acetate-dependent interaction of protein kinase Calpha and the neuronal glutamate transporter EAAC1.
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| González MI, Bannerman PG, Robinson MB.
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| J Neurosci. 23(13):5589-93. 2003
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19 | ARL6IP5, SLC1A1
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| Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18.
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| Lin CI, Orlov I, Ruggiero AM, Dykes-Hoberg M, Lee A, Jackson M, Rothstein JD.
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| Nature 410(6824):84-8. 2001
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20 | SLC1A1, SLC1A2, SLC1A3
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| Na(+)-dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) of the blood-brain barrier. A mechanism for glutamate removal.
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| O'Kane RL, Martinez-Lopez I, DeJoseph MR, Vina JR, Hawkins RA.
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| J Biol Chem 274(45):31891-5 1999
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21 | SLC1A1, SLC1A2
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| Identification of functional domains of the human glutamate transporters EAAT1 and EAAT2.
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| Mitrovic AD, et al.
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| J Biol Chem 273 : 14698-14706. 1998
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22 | SLC1A1, SLC1A2, SLC1A3, SLC1A4, SLC1A5
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| Membrane topology of the high-affinity L-glutamate transporter (GLAST-1) of the central nervous system.
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| Wahle S, Stoffel W.
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| J Cell Biol 135 : 1867-1877. 1996
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23 | SLC1A1, SLC1A2
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| Membrane topology of the C-terminal half of the neuronal, glial, and bacterial glutamate transporter family.
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| Slotboom DJ, Lolkema JS, Konings WN.
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| J Biol Chem 271 : 31317-31321. 1996
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24 | SLC1A1
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| Assignment of the gene coding for the human high-affinity glutamate transporter EAAC1 to 9p24 : potential role in dicarboxylic aminoaciduria and neurodegenerative disorders.
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| Smith CP, et al.
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| Genomics 20 : 335-336. 1994
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25 | SLC1A1, SLC1A3
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| The mouse and human excitatory amino acid transporter gene (EAAT1) maps to mouse chromosome 15 and a region of syntenic homology on human chromosome 5.
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| Kirschner MA, et al.
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| Genomics 22 : 631-633. 1994
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26 | SLC1A1
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| Neuron-specific human glutamate transporter : molecular cloning, characterization and expression in human brain.
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| Shashidharan P, et al.
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| Brain Res 662 : 245-250. 1994
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27 | SLC1A1
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| Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex.
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| Arriza JL, Fairman WA, Wadiche JI, Murdoch GH, Kavanaugh MP, Amara SG.
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| J Neurosci. 14(9):5559-69. 1994
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28 | SLC1A1
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| Primary structure and functional characterization of a high-affinity glutamate transporter.
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| Kanai Y, et al.
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| Nature 360 : 467-471. 1992
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