Citations for
1SLC10A2
Human bile acid transporter ASBT (SLC10A2) forms functional non-covalent homodimers and higher order oligomers.
Chothe PP, Czuba LC, Moore RH, Swaan PW.
Biochim Biophys Acta Biomembr 1860(3):645-653. doi: 10.1016/j.bbamem.2017.11.016. Epub 2017 Dec 1. 2018
2SLC10A2
An important intestinal transporter that regulates the enterohepatic circulation of bile acids and cholesterol homeostasis: The apical sodium-dependent bile acid transporter (SLC10A2/ASBT).
Xiao L, Pan G.
Clin Res Hepatol Gastroenterol 41(5):509-515. doi: 10.1016/j.clinre.2017.02.001. Epub 2017 Mar 21. Review. 2017
3SLC10A2
Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids.
Raufman JP, Dawson PA, Rao A, Drachenberg CB, Heath J, Shang AC, Hu S, Zhan M, Polli JE, Cheng K.
Carcinogenesis 36(10):1193-200. doi: 10.1093/carcin/bgv107. Epub 2015 Jul 25. 2015
4GATA4, SLC10A2
Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4.
Out C, Patankar JV, Doktorova M, Boesjes M, Bos T, de Boer S, Havinga R, Wolters H, Boverhof R, van Dijk TH, Smoczek A, Bleich A, Sachdev V, Kratky D, Kuipers F, Verkade HJ, Groen AK.
J Hepatol 63(3):697-704. doi: 10.1016/j.jhep.2015.04.030. Epub 2015 May 27. 2015
5SLC10A2
N-glycosylation is essential for ileal ASBT function and protection against proteases.
Muthusamy S, Malhotra P, Hosameddin M, Dudeja AK, Borthakur S, Saksena S, Gill RK, Dudeja PK, Alrefai WA.
Am J Physiol Cell Physiol 308(12):C964-71. doi: 10.1152/ajpcell.00023.2015. Epub 2015 Apr 8. 2015
6SLC10A2
Transmembrane domain V plays a stabilizing role in the function of human bile acid transporter SLC10A2.
Moore RH, Chothe P, Swaan PW.
Biochemistry 52(30):5117-24. doi: 10.1021/bi400028q. Epub 2013 Jul 16. 2013
7SLC10A2
Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids.
Miyata M, Yamakawa H, Hayashi K, Kuribayashi H, Yamazoe Y, Yoshinari K.
Eur J Pharmacol 714(1-3):507-14. doi: 10.1016/j.ejphar.2013.06.036. Epub 2013 Jul 18. 2013
8SLC10A2
Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2).
Lionarons DA, Boyer JL, Cai SY.
J Lipid Res 53(8):1535-42. doi: 10.1194/jlr.M025726. Epub 2012 Jun 5. 2012
9SLC10A2
Regulation of the gene encoding the intestinal bile acid transporter ASBT by the caudal-type homeobox proteins CDX1 and CDX2.
Ma L, Jüttner M, Kullak-Ublick GA, Eloranta JJ.
Am J Physiol Gastrointest Liver Physiol 302(1):G123-33. doi: 10.1152/ajpgi.00102.2011. Epub 2011 Oct 20. 2012
10SLC10A2
Transmembrane helix 1 contributes to substrate translocation and protein stability of bile acid transporter SLC10A2.
da Silva TC, Hussainzada N, Khantwal CM, Polli JE, Swaan PW.
J Biol Chem 286(31):27322-32. Epub 2011 Jun 6. 2011
11SLC10A2
Transmembrane helix 1 contributes to substrate translocation and protein stability of bile acid transporter SLC10A2.
da Silva TC, Hussainzada N, Khantwal CM, Polli JE, Swaan PW.
J Biol Chem 286(31):27322-32. doi: 10.1074/jbc.M110.217802. Epub 2011 Jun 6. 2011
12SLC10A2
Apical sodium-dependent bile acid transporter upregulation is associated with necrotizing enterocolitis.
Halpern MD, Weitkamp JH, Mount Patrick SK, Dobrenen HJ, Khailova L, Correa H, Dvorak B.
Am J Physiol Gastrointest Liver Physiol 299(3):G623-31. doi: 10.1152/ajpgi.00242.2010. Epub 2010 Jul 8. 2010
13SLC10A2
Mutation screening of apical sodium-dependent bile acid transporter (SLC10A2): novel haplotype block including six newly identified variants linked to reduced expression.
Renner O, Harsch S, Schaeffeler E, Schwab M, Klass DM, Kratzer W, Stange EF.
Hum Genet 125(4):381-91. Epub 2009 Jan 30. 2009
14ABCA1, ABCG5, ABCG8, ABLP, APOB, APOB, APOC2, ARH, FDB, FHBL1, HCHOLA3, HDLDT1, LDLR, LDLRAP1, LIPAD, LPL, MTTP, PBAM, PCSK9, SLC10A2, STSL
Monogenic pediatric dyslipidemias: classification, genetics and clinical spectrum.
Rahalkar AR, Hegele RA.
Mol Genet Metab 93(3):282-94. Epub 2007 Nov 26. Review. 2008
15SLC10A2
Conserved aspartic acid residues lining the extracellular loop 1 of sodium-coupled bile acid transporter ASBT Interact with Na+ and 7alpha-OH moieties on the ligand cholestane skeleton.
Hussainzada N, Da Silva TC, Zhang EY, Swaan PW.
J Biol Chem 283(30):20653-63. Epub 2008 May 28. 2008
16SLC10A2
Transactivation of the human apical sodium-dependent bile acid transporter gene by human serum.
Duane WC, Xiong W, Lofgren J.
J Steroid Biochem Mol Biol 108(1-2):137-48. Epub 2007 Sep 11. 2008
17SLC10A1, SLC10A2, SLC10A3, SLC10A4, SLC10A5, SLC10A6
The solute carrier family SLC10: more than a family of bile acid transporters regarding function and phylogenetic relationships.
Geyer J, Wilke T, Petzinger E.
Naunyn Schmiedebergs Arch Pharmacol 372(6):413-31. Epub 2006 Mar 16. Review. 2006
18SLC10A2
Bile acid-induced negative feedback regulation of the human ileal bile acid transporter.
Neimark E, Chen F, Li X, Shneider BL.
Hepatology 40(1):149-56. 2004
19SLC10A2
Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2).
Zhang EY, Phelps MA, Banerjee A, Khantwal CM, Chang C, Helsper F, Swaan PW.
Biochemistry 43(36):11380-92. 2004
20SLC10A2
Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes.
Xia X, Roundtree M, Merikhi A, Lu X, Shentu S, Lesage G.
J Biol Chem 279(43):44931-7. Epub 2004 Aug 10. 2004
21SLC10A2
Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alpha.
Jung D, Fried M, Kullak-Ublick GA.
J Biol Chem 277(34):30559-66. Epub 2002 Jun 07. 2002
22SLC10A2
Analysis of the ileal bile acid transporter gene, SLC10A2, in subjects with familial hypertriglyceridemia.
Love MW, Craddock AL, Angelin B, Brunzell JD, Duane WC, Dawson PA.
Arterioscler Thromb Vasc Biol 21(12):2039-45. 2001
23SLC10A2, PBAM
Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2).
Oelkers P, et al.
J Clin Invest 99 : 1880-1887. 1997
24SLC10A2
Localization of the ileal sodium-bile acid cotransporter gene (SLC10A2) to human chromosome 13q33.
Wong MH, et al.
Genomics 33 : 538-540. 1996
25SLC10A2, PBAM
Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity.
Wong MH, et al.
J Biol Chem 270 : 27228-27234. 1995