1 | FBXO45, NMNAT2, SKP1
|
| PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.
|
| Desbois M, Crawley O, Evans PR, Baker ST, Masuho I, Yasuda R, Grill B.
|
| J Biol Chem 293(36):13897-13909. doi: 10.1074/jbc.RA118.002176. Epub 2018 Jul 11.
2018
|
2 | SKP1, SUGT1
|
| The crystal structure of the Sgt1-Skp1 complex: the link between Hsp90 and both SCF E3 ubiquitin ligases and kinetochores.
|
| Willhoft O, Kerr R, Patel D, Zhang W, Al-Jassar C, Daviter T, Millson SH, Thalassinos K, Vaughan CK.
|
| Sci Rep 7:41626. doi: 10.1038/srep41626.
2017
|
3 | SKP1
|
| Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex.
|
| Yumimoto K, Muneoka T, Tsuboi T, Nakayama KI.
|
| J Biol Chem 288(45):32766-76. doi: 10.1074/jbc.M113.511303. Epub 2013 Sep 30.
2013
|
4 | CUL1, SF3B3, SKP1, SKP2
|
| Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130).
|
| Cordero-Espinoza L, Hagen T.
|
| Biol Open 2(8):838-44. doi: 10.1242/bio.20134374. eCollection 2013 Aug 15.
2013
|
5 | FBXO7, SKP1
|
| Targeting SKP1, an ubiquitin E3 ligase component found decreased in sporadic Parkinson's disease.
|
| Mandel SA, Fishman-Jacob T, Youdim MB.
|
| Neurodegener Dis 10(1-4):220-3. doi: 10.1159/000333223. Epub 2011 Dec 23. Review.
2012
|
6 | SKP1
|
| Genetic reduction of the E3 ubiquitin ligase element, SKP1A and environmental manipulation to emulate cardinal features of Parkinson's disease.
|
| Mandel SA, Fishman-Jacob T, Youdim MB.
|
| Parkinsonism Relat Disord 18 Suppl 1:S177-9. doi: 10.1016/S1353-8020(11)70055-4.
2012
|
7 | BRCA1, FBXO44, SKP1
|
| The F-box protein FBXO44 mediates BRCA1 ubiquitination and degradation.
|
| Lu Y, Li J, Cheng D, Parameswaran B, Zhang S, Jiang Z, Yew PR, Peng J, Ye Q, Hu Y.
|
| J Biol Chem 287(49):41014-22. doi: 10.1074/jbc.M112.407106. Epub 2012 Oct 18.
2012
|
8 | CUL1, DRG2, SKP1
|
| SKP1-CULLIN1-F-box (SCF)-mediated DRG2 degradation facilitated chemotherapeutic drugs induced apoptosis in hepatocellular carcinoma cells.
|
| Chen J, Shen BY, Deng XX, Zhan Q, Peng CH.
|
| Biochem Biophys Res Commun 420(3):651-5. doi: 10.1016/j.bbrc.2012.03.058. Epub 2012 Mar 17.
2012
|
9 | FBXO2, FBXO6, SKP1
|
| Skp1 stabilizes the conformation of F-box proteins.
|
| Yoshida Y, Murakami A, Tanaka K.
|
| Biochem Biophys Res Commun 410(1):24-8. doi: 10.1016/j.bbrc.2011.05.098. Epub 2011 May 24.
2011
|
10 | FBXO7, SKP1, XPO1
|
| A Competitive binding mechanism between Skp1 and exportin 1 (CRM1) controls the localization of a subset of F-box proteins.
|
| Nelson DE, Laman H.
|
| J Biol Chem 286(22):19804-15. doi: 10.1074/jbc.M111.220079. Epub 2011 Mar 4.
2011
|
11 | MIS12, SKP1
|
| Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites.
|
| Davies AE, Kaplan KB.
|
| J Cell Biol 189(2):261-74. doi: 10.1083/jcb.200910036.
2010
|
12 | FBXO2, FBXO44, SKP1
|
| Crystallization and preliminary X-ray characterization of the Skp1-Fbg3 complex.
|
| Kumanomidou T, Nakagawa T, Mizushima T, Suzuki A, Tokunaga F, Iwai K, Yoshida Y, Tanaka K, Yamane T.
|
| Acta Crystallogr Sect F Struct Biol Cryst Commun 66(Pt 1):95-8. doi: 10.1107/S1744309109050581. Epub 2009 Dec 25.
2010
|
13 | SKP1
|
| A sporadic Parkinson disease model via silencing of the ubiquitin-proteasome/E3 ligase component SKP1A.
|
| Fishman-Jacob T, Reznichenko L, Youdim MB, Mandel SA.
|
| J Biol Chem 284(47):32835-45. Epub 2009 Sep 11.PMID: 19748892 2009
|
14 | CUL7, FBXW8, SKP1
|
| The cullin7 E3 ubiquitin ligase: a novel player in growth control.
|
| Sarikas A, Xu X, Field LJ, Pan ZQ.
|
| Cell Cycle 7(20):3154-61. Epub 2008 Oct 4. Review.PMID: 18927510 2008
|
15 | CUL7, IRS1, SKP1
|
| The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation.
|
| Xu X, Sarikas A, Dias-Santagata DC, Dolios G, Lafontant PJ, Tsai SC, Zhu W, Nakajima H, Nakajima HO, Field LJ, Wang R, Pan ZQ.
|
| Mol Cell 30(4):403-14.PMID: 18498745 2008
|
16 | FBXO2, SKP1
|
| Selective cochlear degeneration in mice lacking the F-box protein, Fbx2, a glycoprotein-specific ubiquitin ligase subunit.
|
| Nelson RF, Glenn KA, Zhang Y, Wen H, Knutson T, Gouvion CM, Robinson BK, Zhou Z, Yang B, Smith RJ, Paulson HL.
|
| J Neurosci 27(19):5163-71.
2007
|
17 | CENPE, SKP1
|
| Interaction of Skp1 with CENP-E at the midbody is essential for cytokinesis.
|
| Liu D, Zhang N, Du J, Cai X, Zhu M, Jin C, Dou Z, Feng C, Yang Y, Liu L, Takeyasu K, Xie W, Yao X.
|
| Biochem Biophys Res Commun 345(1):394-402. Epub 2006 Apr 25.
2006
|
18 | SKP1
|
| Involvement of the SCF complex in the control of Cdh1 degradation in S-phase.
|
| Benmaamar R, Pagano M.
|
| Cell Cycle 4(9):1230-2. Epub 2005 Sep 20.
2005
|
19 | OCP1, SKP1
|
| The cochlear F-box protein OCP1 associates with OCP2 and connexin 26.
|
| Henzl MT, Thalmann I, Larson JD, Ignatova EG, Thalmann R.
|
| Hear Res 191(1-2):101-9. 2004
|
20 | ELOC, SKP1
|
| Identification of Elongin C and Skp1 sequences that determine Cullin selection.
|
| Yan Q, Kamura T, Cai Y, Jin J, Ivan M, Mushegian A, Conaway RC, Conaway JW.
|
| J Biol Chem 279(41):43019-26. Epub 2004 Jul 27. 2004
|
21 | FBXO2, SKP1
|
| The cochlear F-box protein OCP1 associates with OCP2 and connexin 26.
|
| Henzl MT, Thalmann I, Larson JD, Ignatova EG, Thalmann R.
|
| Hear Res 191(1-2):101-9.
2004
|
22 | CDCA3, SKP1, WEE1
|
| Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC.
|
| Ayad NG, Rankin S, Murakami M, Jebanathirajah J, Gygi S, Kirschner MW.
|
| Cell 113(1):101-13.
2003
|
23 | CUL1, SKP1
|
| In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation.
|
| Piva R, Liu J, Chiarle R, Podda A, Pagano M, Inghirami G.
|
| Mol Cell Biol 22(23):8375-87. 2002
|
24 | CUL1, RBX1, SKP1, SKP1B, SKP2
|
| Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
|
| Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP.
|
| Nature 416(6882):703-9. 2002
|
25 | SKP1, SKP1B, SKP2
|
| Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
|
| Schulman BA, Carrano AC, Jeffrey PD, Bowen Z, Kinnucan ER, Finnin MS, Elledge SJ, Harper JW, Pagano M, Pavletich NP.
|
| Nature 408(6810):381-6. 2000
|
26 | CCNF, FBXL12, FBXL6, FBXO10, FBXO11, FBXO18, FBXO2, FBXO3, FBXO4, FBXO8, FBXW5, FBXW5, FBXW7, FBXW8, KDM2A, SHFM3P1, SKP1, TSPAN17
|
| A family of mammalian F-box proteins.
|
| Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW.
|
| Curr Biol 9(20):1180-2. 1999
|
27 | SKP1, SKP1B, SKP2
|
| Characterization of the cullin and F-box protein partner Skp1.
|
| Ng RW, Arooz T, Yam CH, Chan IW, Lau AW, Poon RY.
|
| FEBS Lett 438 : 183-189. 1998
|
28 | SKP1, SKP1B, SKP2
|
| Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2).
|
| Demetrick DJ, et al.
|
| Cytogenet Cell Genet 73 : 104-107. 1996
|
29 | SKP1, SKP1B, SKP2
|
| SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.
|
| Bai C, et al.
|
| Cell 86(2):263-74 1996
|
30 | SKP1, SKP1B, SKP2
|
| p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase.
|
| Zhang H, Kobayashi R, Galaktionov K, Beach D.
|
| Cell 82(6):915-25. 1995
|