| 1 | SGS2, SKI
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| In-Frame Mutations in Exon 1 of SKI Cause Dominant Shprintzen-Goldberg Syndrome.
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| Carmignac V, Thevenon J, Adès L, Callewaert B, Julia S, Thauvin-Robinet C, Gueneau L, Courcet JB, Lopez E, Holman K, Renard M, Plauchu H, Plessis G, De Backer J, Child A, Arno G, Duplomb L, Callier P, Aral B, Vabres P, Gigot N, Arbustini E, Grasso M, Robinson PN, Goizet C, Baumann C, Di Rocco M, Sanchez Del Pozo J, Huet F, Jondeau G, Collod-Beroud G, Beroud C, Amiel J, Cormier-Daire V, Rivière JB, Boileau C, De Paepe A, Faivre L.
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| Am J Hum Genet 91(5):950-7. doi: 10.1016/j.ajhg.2012.10.002. Epub 2012 Oct 25.
2012
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| 2 | SATB2, SKI
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| Protooncogene Ski cooperates with the chromatin-remodeling factor Satb2 in specifying callosal neurons.
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| Baranek C, Dittrich M, Parthasarathy S, Bonnon CG, Britanova O, Lanshakov D, Boukhtouche F, Sommer JE, Colmenares C, Tarabykin V, Atanasoski S.
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| Proc Natl Acad Sci U S A. 109(9):3546-51 2012
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| 3 | SGS2, SKI
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| Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm.
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| Doyle AJ, Doyle JJ, Bessling SL, Maragh S, Lindsay ME, Schepers D, Gillis E, Mortier G, Homfray T, Sauls K, Norris RA, Huso ND, Leahy D, Mohr DW, Caulfield MJ, Scott AF, Destrée A, Hennekam RC, Arn PH, Curry CJ, Van Laer L, McCallion AS, Loeys BL, Dietz HC.
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| Nat Genet 44(11):1249-54. doi: 10.1038/ng.2421. Epub 2012 Sep 30.
2012
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| 4 | MDM2, RWDD3, SKI, SRSF1, UBE2I
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| Overexpression of SKI oncoprotein leads to p53 degradation through regulation of MDM2 protein sumoylation.
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| Ding B, Sun Y, Huang J.
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| J Biol Chem 287(18):14621-30. doi: 10.1074/jbc.M111.301523. Epub 2012 Mar 12.
2012
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| 5 | AURKA, SKI
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| Identification of Ski as a target for Aurora A kinase.
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| Mosquera J, Armisen R, Zhao H, Rojas DA, Maldonado E, Tapia JC, Colombo A, Hayman MJ, Marcelain K.
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| Biochem Biophys Res Commun 409(3):539-43. Epub 2011 May 12.
2011
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| 6 | SKI
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| Suppression of p53 activity through the cooperative action of Ski and histone deacetylase SIRT1.
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| Inoue Y, Iemura S, Natsume T, Miyazawa K, Imamura T.
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| J Biol Chem. 286(8):6311-20 2011
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| 7 | DEL1P36, GABRD, PRKCZ, SKI
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| Refinement of causative genes in monosomy 1p36 through clinical and molecular cytogenetic characterization of small interstitial deletions.
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| Rosenfeld JA, Crolla JA, Tomkins S, Bader P, Morrow B, Gorski J, Troxell R, Forster-Gibson C, Cilliers D, Hislop RG, Lamb A, Torchia B, Ballif BC, Shaffer LG.
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| Am J Med Genet A 152A(8):1951-9.PMID: 20635359 2010
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| 8 | HDAC3, SIAH2, SKI
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| The Ski protein negatively regulates Siah2-mediated HDAC3 degradation.
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| Zhao HL, Ueki N, Hayman MJ.
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| Biochem Biophys Res Commun 399(4):623-8. Epub 2010 Aug 4.
2010
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| 9 | SKI
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| The oncoprotein c-ski functions as a direct antagonist of the transforming growth factor-{beta} type I receptor.
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| Ferrand N, Atfi A, Prunier C.
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| Cancer Res. 70(21):8457-66. 2010
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| 10 | PRDM16, SKI
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| SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells.
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| Takahata M, Inoue Y, Tsuda H, Imoto I, Koinuma D, Hayashi M, Ichikura T, Yamori T, Nagasaki K, Yoshida M, Matsuoka M, Morishita K, Yuki K, Hanyu A, Miyazawa K, Inazawa J, Miyazono K, Imamura T.
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| J Biol Chem 284(5):3334-44. Epub 2008 Dec 1.
2009
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| 11 | SKI, SLKI
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| The Ski protein can inhibit ligand induced RARalpha and HDAC3 degradation in the retinoic acid signaling pathway.
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| Zhao HL, Ueki N, Marcelain K, Hayman MJ.
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| Biochem Biophys Res Commun 383(1):119-24. Epub 2009 Mar 31. 2009
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| 12 | PRMT5, SKI
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| Ski co-repressor complexes maintain the basal repressed state of the TGF-beta target gene, SMAD7, via HDAC3 and PRMT5.
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| Tabata T, Kokura K, Ten Dijke P, Ishii S.
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| Genes Cells. 14(1):17-28. 2009
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| 13 | SKI
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| The phosphatidylinositol 3-kinase/Akt pathway regulates transforming growth factor-{beta} signaling by destabilizing ski and inducing Smad7.
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| Band AM, Björklund M, Laiho M.
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| J Biol Chem. 284(51):35441-9 2009
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| 14 | SKI
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| Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3.
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| Zhang H, Stavnezer E.
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| J Biol Chem. 284(5):2867-79. 2009
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| 15 | EYA3, MYOG, SIX1, SKI
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| Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3.
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| Zhang H, Stavnezer E.
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| J Biol Chem 284(5):2867-79. doi: 10.1074/jbc.M807526200. Epub 2008 Nov 12.
2009
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| 16 | SKI, SPI1
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| Ski can negatively regulates macrophage differentiation through its interaction with PU.1.
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| Ueki N, Zhang L, Hayman MJ.
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| Oncogene 27(3):300-7. Epub 2007 Jul 9. Erratum in: Oncogene. 2008 Feb 21;27(9):1344. Haymann, MJ [corrected to Hayman, MJ].
2008
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| 17 | SKI
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| Ski can negatively regulates macrophage differentiation through its interaction with PU.1.
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| Ueki N, Zhang L, Hayman MJ.
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| Oncogene. 27(3):300-7. 2008
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| 18 | SKI
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| Inhibition of retinoic acid receptor signaling by Ski in acute myeloid leukemia.
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| Ritter M, Kattmann D, Teichler S, Hartmann O, Samuelsson MK, Burchert A, Bach JP, Kim TD, Berwanger B, Thiede C, Jäger R, Ehninger G, Schäfer H, Ueki N, Hayman MJ, Eilers M, Neubauer A.
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| Leukemia. 20(3):437-43. 2006
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| 19 | SKI
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| Genetic variation in the proto-oncogene SKI and risk for orofacial clefting.
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| Lu W, Volcik K, Zhu H, Wen S, Shaw GM, Lammer EJ, Finnell RH.
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| Mol Genet Metab 86(3):412-6. Epub 2005 Jul 28. 2005
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| 20 | SKI
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| The Ski oncoprotein is upregulated and localized at the centrosomes and mitotic spindle during mitosis.
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| Marcelain K, Hayman MJ.
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| Oncogene. 24(27):4321-9 2005
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| 21 | SKI
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| Ski negatively regulates erythroid differentiation through its interaction with GATA1.
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| Ueki N, Zhang L, Hayman MJ.
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| Mol Cell Biol. 24(23):10118-25. 2004
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| 22 | SKI
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| Oncogenic activation of c-Myb correlates with a loss of negative regulation by TIF1beta and Ski.
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| Nomura T, Tanikawa J, Akimaru H, Kanei-Ishii C, Ichikawa-Iwata E, Khan MM, Ito H, Ishii S.
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| J Biol Chem. 279(16):16715-26 2004
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| 23 | SKI
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| Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski.
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| Takeda M, Mizuide M, Oka M, Watabe T, Inoue H, Suzuki H, Fujita T, Imamura T, Miyazono K, Miyazawa K.
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| Mol Cell Biol. 15(3):963-72. 2004
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| 24 | SKI
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| c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements.
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| Suzuki H, Yagi K, Kondo M, Kato M, Miyazono K, Miyazawa K.
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| Oncogene. 23(29):5068-76. 2004
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| 25 | SKI
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| The protooncogene Ski controls Schwann cell proliferation and myelination.
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| Atanasoski S, Notterpek L, Lee HY, Castagner F, Young P, Ehrengruber MU, Meijer D, Sommer L, Stavnezer E, Colmenares C, Suter U.
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| Neuron. 43(4):499-511. 2004
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| 26 | SKI
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| Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation.
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| Harada J, Kokura K, Kanei-Ishii C, Nomura T, Khan MM, Kim Y, Ishii S.
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| J Biol Chem. 278(40):38998-9005 2003
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| 27 | SKI
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| Direct interaction of Ski with either Smad3 or Smad4 is necessary and sufficient for Ski-mediated repression of transforming growth factor-beta signaling.
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| Ueki N, Hayman MJ.
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| J Biol Chem. 278(35):32489-92. 2003
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| 28 | SKI
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| Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN.
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| Mizuide M, Hara T, Furuya T, Takeda M, Kusanagi K, Inada Y, Mori M, Imamura T, Miyazawa K, Miyazono K.
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| J Biol Chem. 278(1):531-6 2003
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| 29 | SKI
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| Loss of the SKI proto-oncogene in individuals affected with 1p36 deletion syndrome is predicted by strain-dependent defects in Ski-/- mice.
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| Colmenares C, Heilstedt HA, Shaffer LG, Schwartz S, Berk M, Murray JC, Stavnezer E.
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| Nat Genet 30(1):106-9. 2002
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| 30 | CREB1, MAPK8, SKI, JUN, SMAD2
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| c-Jun associates with the oncoprotein Ski and suppresses Smad2 transcriptional activity.
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| Pessah M, Marais J, Prunier C, Ferrand N, Lallemand F, Mauviel A, Atfi A.
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| J Biol Chem 277(32):29094-100. 2002
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| 31 | GLI3, SKI
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| Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3.
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| Dai P, Shinagawa T, Nomura T, Harada J, Kaul SC, Wadhwa R, Khan MM, Akimaru H, Sasaki H, Colmenares C, Ishii S.
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| Genes Dev. 16(22):2843-8. 2002
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| 32 | PML, SKI
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| Role of PML and PML-RARalpha in Mad-mediated transcriptional repression.
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| Khan MM, Nomura T, Kim H, Kaul SC, Wadhwa R, Shinagawa T, Ichikawa-Iwata E, Zhong S, Pandolfi PP, Ishii S.
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| Mol Cell. 7(6):1233-43 2001
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| 33 | MECP2, SKI
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| The Ski protein family is required for MeCP2-mediated transcriptional repression.
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| Kokura K, Kaul SC, Wadhwa R, Nomura T, Khan MM, Shinagawa T, Yasukawa T, Colmenares C, Ishii S.
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| J Biol Chem. 276(36):34115-21. 2001
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| 34 | SKI
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| Ski interacts with the evolutionarily conserved SNW domain of Skip.
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| Prathapam T, Kühne C, Hayman M, Banks L.
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| Nucleic Acids Res. 29(17):3469-76. 2001
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| 35 | SKI
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| Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice.
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| Shinagawa T, Nomura T, Colmenares C, Ohira M, Nakagawara A, Ishii S.
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| Oncogene. 20(56):8100-8. 2001
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| 36 | SKI
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| Ectopic expression of c-ski disrupts gastrulation and neural patterning in zebrafish.
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| Kaufman CD, Martínez-Rodriguez G, Hackett PB Jr.
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| Mech Dev. 95(1-2):147-62. 2000
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| 37 | SKI
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| Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling.
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| Sun Y, Liu X, Eaton EN, Lane WS, Lodish HF, Weinberg RA.
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| Mol Cell 4(4):499-509. 1999
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| 38 | SKI
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| c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads.
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| Akiyoshi S, Inoue H, Hanai J, Kusanagi K, Nemoto N, Miyazono K, Kawabata M.
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| J Biol Chem. 274(49):35269-77. 1999
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| 39 | SKI
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| Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents.
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| Cohen SB, Zheng G, Heyman HC, Stavnezer E.
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| Nucleic Acids Res. 27(4):1006-14. 1999
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| 40 | SKI
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| The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling.
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| Luo K, Stroschein SL, Wang W, Chen D, Martens E, Zhou S, Zhou Q.
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| Genes Dev. 13(17):2196-206. 1999
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| 41 | SKI
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| Viral ski inhibits retinoblastoma protein (Rb)-mediated transcriptional repression in a dominant negative fashion.
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| Tokitou F, Nomura T, Khan MM, Kaul SC, Wadhwa R, Yasukawa T, Kohno I, Ishii S.
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| J Biol Chem. 274(8):4485-8. 1999
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| 42 | SKI, SNW1
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| The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42.
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| Dahl R, Wani B, Hayman MJ.
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| Oncogene 16(12):1579-86. 1998
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| 43 | SKI
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| DNA binding and transcriptional activation by the Ski oncoprotein mediated by interaction with NFI.
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| Tarapore P, Richmond C, Zheng G, Cohen SB, Kelder B, Kopchick J, Kruse U, Sippel AE, Colmenares C, Stavnezer E.
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| Nucleic Acids Res. 25(19):3895-903. 1997
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| 44 | SKI
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| Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development.
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| Berk M, Desai SY, Heyman HC, Colmenares C.
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| Genes Dev. 11(16):2029-39. 1997
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| 45 | SKI, SKIL
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| Isolation of human cDNA clones of ski and the ski-related gene, sno.
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| Nomura N, Sasamoto S, Ishii S, Date T, Matsui M, Ishizaki R.
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| Nucleic Acids Res 17(14):5489-500. 1989
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| 46 | SKI
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| The cellular homologue of the transforming gene of SKV avian retrovirus maps to human chromosome region 1q22->q24.
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| Chaganti RSK, et al.
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| Cytogenet Cell Genet 43 : 181-186. 1986
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| 47 | SKI
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| Assignment of the human homologue of a chicken oncogene to chromosome 1.
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| Balazs I, et al.
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| (HGM7) Cytogenet Cell Genet 37 : 410-411. 1984
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