| 1 | SALL1, SIX2
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| A Sall1-NuRD interaction regulates multipotent nephron progenitors and is required for loop of Henle formation.
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| Basta JM, Robbins L, Denner DR, Kolar GR, Rauchman M.
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| Development 144(17):3080-3094. doi: 10.1242/dev.148692. Epub 2017 Jul 31.
2017
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| 2 | BARX1, ISL1, PITX1, PITX2, SIX2
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| Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1.
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| Jayewickreme CD, Shivdasani RA.
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| Dev Biol 405(1):21-32. doi: 10.1016/j.ydbio.2015.05.024. Epub 2015 Jun 6.
2015
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| 3 | SIX1, SIX2, SIX4
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| Combinatorial activity of Six1-2-4 genes in cephalic neural crest cells controls craniofacial and brain development.
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| Garcez RC, Le Douarin NM, Creuzet SE.
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| Cell Mol Life Sci 71(11):2149-64. doi: 10.1007/s00018-013-1477-z. Epub 2013 Sep 24.
2014
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| 4 | EYA1, MYC, SIX2
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| Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis.
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| Xu J, Wong EY, Cheng C, Li J, Sharkar MT, Xu CY, Chen B, Sun J, Jing D, Xu PX.
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| Dev Cell 31(4):434-47. doi: 10.1016/j.devcel.2014.10.015. Epub 2014 Nov 24.
2014
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| 5 | SALL1, SIX2
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| Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor.
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| Kanda S, Tanigawa S, Ohmori T, Taguchi A, Kudo K, Suzuki Y, Sato Y, Hino S, Sander M, Perantoni AO, Sugano S, Nakao M, Nishinakamura R.
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| J Am Soc Nephrol 25(11):2584-95. doi: 10.1681/ASN.2013080896. Epub 2014 Apr 17.
2014
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| 6 | SIX2, WNT9B
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| Conditional expression of Wnt9b in Six2-positive cells disrupts stomach and kidney function.
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| Kiefer SM, Robbins L, Rauchman M.
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| PLoS One 7(8):e43098. doi: 10.1371/journal.pone.0043098. Epub 2012 Aug 17.
2012
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| 7 | SIX2
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| Inactivation of Six2 in mouse identifies a novel genetic mechanism controlling development and growth of the cranial base.
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| He G, Tavella S, Hanley KP, Self M, Oliver G, Grifone R, Hanley N, Ward C, Bobola N.
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| Dev Biol 344(2):720-30. Epub 2010 May 31.PMID: 20515681 2010
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| 8 | SIX2
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| Six2 activity is required for the formation of the mammalian pyloric sphincter.
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| Self M, Geng X, Oliver G.
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| Dev Biol 334(2):409-17. Epub 2009 Aug 3.PMID: 19660448 2009
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| 9 | HOXA2, SIX2
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| Six2 functions redundantly immediately downstream of Hoxa2.
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| Kutejova E, Engist B, Self M, Oliver G, Kirilenko P, Bobola N.
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| Development 135(8):1463-70. Epub 2008 Mar 5.PMID: 18321982 2008
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| 10 | BMP4, SIX2
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| SIX2 and BMP4 mutations associate with anomalous kidney development.
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| Weber S, Taylor JC, Winyard P, Baker KF, Sullivan-Brown J, Schild R, Knüppel T, Zurowska AM, Caldas-Alfonso A, Litwin M, Emre S, Ghiggeri GM, Bakkaloglu A, Mehls O, Antignac C, Network E, Schaefer F, Burdine RD.
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| J Am Soc Nephrol 19(5):891-903. Epub 2008 Feb 27.PMID: 18305125 2008
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| 11 | SIX2
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| Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney.
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| Self M, Lagutin OV, Bowling B, Hendrix J, Cai Y, Dressler GR, Oliver G.
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| EMBO J 25(21):5214-28. Epub 2006 Oct 12.PMID: 17036046 2006
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| 12 | HOXA2, SIX2
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| Hoxa2 downregulates Six2 in the neural crest-derived mesenchyme.
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| Kutejova E, Engist B, Mallo M, Kanzler B, Bobola N.
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| Development 132(3):469-78. Epub 2005 Jan 5.PMID: 15634706 2005
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| 13 | GDNF, SIX2
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| The transcription factor Six2 activates expression of the Gdnf gene as well as its own promoter.
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| Brodbeck S, Besenbeck B, Englert C.
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| Mech Dev 121(10):1211-22.PMID: 15327782 2004
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| 14 | SIX2
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| Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2.
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| Boucher CA, Winchester CL, Hamilton GM, Winter AD, Johnson KJ, Bailey ME.
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| Gene 247(1-2):145-51. 2000
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| 15 | BAPA, SIX2, SIX4, SIX6, DEL14Q22
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| Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies.
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| Gallardo ME, Lopez-Rios J, Fernaud-Espinosa I, Granadino B, Sanz R, Ramos C, Ayuso C, Seller MJ, Brunner HG, Bovolenta P, Rodriguez de Cordoba S.
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| Genomics 61(1):82-91. 1999
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