Citations for
1GREM1, SIX1
Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis.
Nie X, Xu J, El-Hashash A, Xu PX.
Dev Biol 352(1):141-51. Epub 2011 Jan 31. 2011
2SIX1
Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung.
El-Hashash AH, Al Alam D, Turcatel G, Rogers O, Li X, Bellusci S, Warburton D.
Dev Biol 353(2):242-58. Epub 2011 Mar 6. 2011
3SIX1, TBX18
SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation.
Nie X, Sun J, Gordon RE, Cai CL, Xu PX.
Development 137(5):755-65. Epub 2010 Jan 28. 2010
4BOR3, BOS3, SIX1
Biochemical and Functional Characterization of Six SIX1 Branchio-oto-renal Syndrome Mutations.
Patrick AN, Schiemann BJ, Yang K, Zhao R, Ford HL.
J Biol Chem 284(31):20781-90. Epub 2009 Jun 4. 2009
5GBX2, SIX1, ZIC1
The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction.
Li B, Kuriyama S, Moreno M, Mayor R.
Development 136(19):3267-78. 2009
6BOR3, BOS3, SIX1
SIX1 mutation screening in 247 branchio-oto-renal syndrome families: a recurrent missense mutation associated with BOR.
Kochhar A, Orten DJ, Sorensen JL, Fischer SM, Cremers CW, Kimberling WJ, Smith RJ.
Hum Mutat 29(4):565. 2008
7OTX2, SIX1, SIX6
Branchiootorenal syndrome and oculoauriculovertebral spectrum features associated with duplication of SIX1, SIX6, and OTX2 resulting from a complex chromosomal rearrangement.
Ou Z, Martin DM, Bedoyan JK, Cooper ML, Chinault AC, Stankiewicz P, Cheung SW.
Am J Med Genet A 146A(19):2480-9. 2008
8EYA1, BOR1, SIX1, BOS3
Branchio-oto-renal syndrome: detection of EYA1 and SIX1 mutations in five out of six Danish families by combining linkage, MLPA and sequencing analyses.
Sanggaard KM, Rendtorff ND, Kjaer KW, Eiberg H, Johnsen T, Gimsing S, Dyrmose J, Nielsen KO, Lage K, Tranebjaerg L.
Eur J Hum Genet 15(11):1121-31. Epub 2007 Jul 18. 2007
9SALL1,SIX1
Transcriptional activation of the SALL1 by the human SIX1 homeodomain during kidney development.
Chai L, Yang J, Di C, Cui W, Kawakami K, Lai R, Ma Y.
J Biol Chem 281(28):18918-26. Epub 2006 May 2. 2006
10SIX1
Clinicopathological significance of homeoprotein Six1 in hepatocellular carcinoma.
Ng KT, Man K, Sun CK, Lee TK, Poon RT, Lo CM, Fan ST.
Br J Cancer 95(8):1050-5. Epub 2006 Sep 26. 2006
11SIX1, EZR
Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators.
Yu Y, Khan J, Khanna C, Helman L, Meltzer PS, Merlino G.
Nat Med 10(2):175-81. Epub 2004 Jan 04. 2004
12BOR3, BOS3, DFNA23, EYA1, SIX1
SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes.
Ruf RG, Xu PX, Silvius D, Otto EA, Beekmann F, Muerb UT, Kumar S, Neuhaus TJ, Kemper MJ, Raymond RM Jr, Brophy PD, Berkman J, Gattas M, Hyland V, Ruf EM, Schwartz C, Chang EH, Smith RJ, Stratakis CA, Weil D, Petit C, Hildebrandt F.
Proc Natl Acad Sci U S A 101(21):8090-5. Epub 2004 May 12. 2004
13EYA1, DACH1, SIX1
Molecular interaction and synergistic activation of a promoter by Six, Eya, and Dach proteins mediated through CREB binding protein.
Ikeda K, Watanabe Y, Ohto H, Kawakami K.
Mol Cell Biol 22(19):6759-66. 2002
14SIX1
Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein.
Ford HL, Landesman-Bollag E, Dacwag CS, Stukenberg PT, Pardee AB, Seldin DC.
J Biol Chem 275(29):22245-54. 2000
15SIX1
Cloning of the human SIX1 gene and its assignment to chromosome 14.
Boucher CA, et al.
Genomics 33 : 140-142. 1996