Citations for
1SIVA1, STMN1, TP53
Overexpression and Characterization of The C-Terminal Domain of Human Siva1, A Proapoptotic Factor and Cytoskeleton Binding Protein.
Dantas LE, Saad ST, Ramos CH, Bénichou S.
Protein Pept Lett 23(1):43-50. 2016
2ANKHD1, SIVA1
ANKHD1 silencing inhibits Stathmin 1 activity, cell proliferation and migration of leukemia cells.
Machado-Neto JA, Lazarini M, Favaro P, de Melo Campos P, Scopim-Ribeiro R, Franchi Junior GC, Nowill AE, Lima PR, Costa FF, Benichou S, Olalla Saad ST, Traina F.
Biochim Biophys Acta 1853(3):583-93. doi: 10.1016/j.bbamcr.2014.12.012. Epub 2014 Dec 16. 2015
3PCNA, RAD18, SIVA1
SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.
Han J, Liu T, Huen MS, Hu L, Chen Z, Huang J.
J Cell Biol 205(6):811-27. doi: 10.1083/jcb.201311007. 2014
4SIVA1, TP53
Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase.
Wang X, Zha M, Zhao X, Jiang P, Du W, Tam AY, Mei Y, Wu M.
Nat Commun 4:1551. doi: 10.1038/ncomms2533. 2013
5SIVA1
Thromboxane A2 modulates cisplatin-induced apoptosis through a Siva1-dependent mechanism.
Iorio-Morin C, Germain P, Roy S, Génier S, Labrecque P, Parent JL.
Cell Death Differ 19(8):1347-57. doi: 10.1038/cdd.2012.11. Epub 2012 Feb 17. 2012
6SIVA1, STMN1
Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules.
Li N, Jiang P, Du W, Wu Z, Li C, Qiao M, Yang X, Wu M.
Proc Natl Acad Sci U S A 108(31):12851-6. Epub 2011 Jul 18. 2011
7FOXP3, NFATC1, SIVA1
Regulation of IL-2 gene expression by Siva and FOXP3 in human T cells.
Hench VK, Su L.
BMC Immunol MC Immunol. 2011 2011
8SIVA1, TYK2
Tyrosine kinase 2 interacts with the proapoptotic protein Siva-1 and augments its apoptotic functions.
Shimoda HK, Shide K, Kameda T, Matsunaga T, Shimoda K.
Biochem Biophys Res Commun 400(2):252-7. Epub 2010 Aug 19. 2010
9FMF, SIVA1
The role of the pro-apoptotic protein Siva in the pathogenesis of Familial Mediterranean fever: A structural and functional analysis.
Goulielmos GN, Petraki E, Vassou D, Eliopoulos E, Iliopoulos D, Sidiropoulos P, Aksentijevich I, Kardassis D, Boumpas DT.
Biochem Biophys Res Commun 402(1):141-6. Epub 2010 Oct 8. 2010
10FHL1, SIVA1
SLIMMER (FHL1B/KyoT3) interacts with the proapoptotic protein Siva-1 (CD27BP) and delays skeletal myoblast apoptosis.
Cottle DL, McGrath MJ, Wilding BR, Cowling BS, Kane JM, D'Arcy CE, Holdsworth M, Hatzinisiriou I, Prescott M, Brown S, Mitchell CA.
J Biol Chem 284(39):26964-77. Epub 2009 Jul 29. 2009
11MDM2, SIVA1, TP53
Suppression of p53 activity by Siva1.
Du W, Jiang P, Li N, Mei Y, Wang X, Wen L, Yang X, Wu M.
Cell Death Differ 16(11):1493-504. Epub 2009 Jul 10.PMID: 19590512 2009
12FMF, MEFV, SIVA1
Pyrin, product of the MEFV locus, interacts with the proapoptotic protein, Siva.
Balci-Peynircioglu B, Waite AL, Hu C, Richards N, Staubach-Grosse A, Yilmaz E, Gumucio DL.
J Cell Physiol 216(3):595-602.PMID: 18330885 2008
13SIVA1, TP53
Siva is an apoptosis-selective p53 target gene important for neuronal cell death.
Jacobs SB, Basak S, Murray JI, Pathak N, Attardi LD.
Cell Death Differ 14(7):1374-85. Epub 2007 Apr 20. 2007
14SIVA1
The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1.
Fortin A, MacLaurin JG, Arbour N, Cregan SP, Kushwaha N, Callaghan SM, Park DS, Albert PR, Slack RS.
J Biol Chem 279(27):28706-14. Epub 2004 Apr 22. 2004
15SIVA1
Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway.
Py B, Slomianny C, Auberger P, Petit PX, Benichou S.
J Immunol 172(7):4008-17. 2004
16SIVA1
The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis.
Chu F, Borthakur A, Sun X, Barkinge J, Gudi R, Hawkins S, Prasad KV.
Apoptosis 9(1):83-95. 2004
17SIVA1
Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis.
Xue L, Chu F, Cheng Y, Sun X, Borthakur A, Ramarao M, Pandey P, Wu M,Schlossman SF, Prasad KV.
Proc Natl Acad Sci U S A 99(10):6925-30. 2002
18SIVA1
CD70/CD27 ligand, a member of the TNF family, is expressed in human brain tumors.
Held-Feindt J, Mentlein R.
Int J Cancer 98(3):352-6. 2002
19ABL2, SIVA1
The ARG tyrosine kinase interacts with Siva-1 in the apoptotic response to oxidative stress.
Cao C, Ren X, Kharbanda S, Koleske A, Prasad KV, Kufe D.
J Biol Chem 276(15):11465-8. Epub 2001 Feb 23. 2001
20SIVA1
CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein.
Prasad KV, Ao Z, Yoon Y, Wu MX, Rizk M, Jacquot S, Schlossman SF.
Proc Natl Acad Sci U S A 94(12):6346-51. 1997