| 1 | SIRT7, SLC12A7
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| SIRT7 modulates the stability and activity of the renal K-Cl cotransporter KCC4 through deacetylation
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| Noriega LG, Melo Z, Rajaram RD, Mercado A, Tovar AR, Velazquez-Villegas LA, Castañeda-Bueno M, Reyes-López Y, Ryu D, Rojas-Vega L, Magaña-Avila G, López-Barradas AM, Sánchez-Hernández M, Debonneville A, Doucet A, Cheval L, Torres N, Auwerx J, Staub O, Gamba G.
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| EMBO Rep. May 5;22(5):e50766. doi: 10.15252/embr.202050766. Epub 2021 Mar 22. 2021
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| 2 | SIRT7, SP7
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| SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.
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| Fukuda M, Yoshizawa T, Karim MF, Sobuz SU, Korogi W, Kobayasi D, Okanishi H, Tasaki M, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K.
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| Nat Commun. Jul 19;9(1):2833. doi: 10.1038/s41467-018-05187-4 2018
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| 3 | CUL4B, DDB1, SIRT7
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| SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes
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| Mo Y, Lin R, Liu P, Tan M, Xiong Y, Guan KL, Yuan HX.
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| FEBS J. Nov;284(21):3619-3636. doi: 10.1111/febs.14259. Epub 2017 Oct 10. 2017
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| 4 | DDX21, SIRT7
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| SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability.
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| Song C, Hotz-Wagenblatt A, Voit R, Grummt I.
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| Genes Dev. Jul 1;31(13):1370-1381. doi: 10.1101/gad.300624.117. Epub 2017 Aug 8. 2017
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| 5 | SIRT7
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| Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response.
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| Kiran S, Oddi V, Ramakrishna G.
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| Exp Cell Res 331(1):123-41. doi: 10.1016/j.yexcr.2014.11.001. Epub 2014 Nov 12.
2015
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| 6 | GABPB1, SIRT7
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| A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function.
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| Ryu D, Jo YS, Lo Sasso G, Stein S, Zhang H, Perino A, Lee JU, Zeviani M, Romand R, Hottiger MO, Schoonjans K, Auwerx J.
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| Cell Metab 20(5):856-69. doi: 10.1016/j.cmet.2014.08.001. Epub 2014 Sep 4.
2014
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| 7 | SIRT6, SIRT7
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| Comparative interactomes of SIRT6 and SIRT7: Implication of functional links to aging.
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| Lee N, Kim DK, Kim ES, Park SJ, Kwon JH, Shin J, Park SM, Moon YH, Wang HJ, Gho YS, Choi KY.
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| Proteomics 14(13-14):1610-22. doi: 10.1002/pmic.201400001. Epub 2014 May 28.
2014
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| 8 | SIRT7
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| SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.
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| Yoshizawa T, Karim MF, Sato Y, Senokuchi T, Miyata K, Fukuda T, Go C, Tasaki M, Uchimura K, Kadomatsu T, Tian Z, Smolka C, Sawa T, Takeya M, Tomizawa K, Ando Y, Araki E, Akaike T, Braun T, Oike Y, Bober E, Yamagata K.
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| Cell Metab 19(4):712-21. doi: 10.1016/j.cmet.2014.03.006.
2014
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| 9 | SIRT7
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| Molecular pathways: emerging roles of mammalian Sirtuin SIRT7 in cancer.
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| Paredes S, Villanova L, Chua KF.
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| Clin Cancer Res 20(7):1741-6. doi: 10.1158/1078-0432.CCR-13-1547. Epub 2014 Feb 17.
2014
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| 10 | SIRT7
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| Sirtuin 7 plays a role in ribosome biogenesis and protein synthesis.
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| Tsai YC, Greco TM, Cristea IM.
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| Mol Cell Proteomics 13(1):73-83. doi: 10.1074/mcp.M113.031377. Epub 2013 Oct 10.
2014
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| 11 | SIRT7
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| SIRT7 an emerging sirtuin: deciphering newer roles.
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| Kim W, Kim JE.
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| J Physiol Pharmacol 64(5):531-4. Review.
2013
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| 12 | SIRT7
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| SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease.
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| Shin J, He M, Liu Y, Paredes S, Villanova L, Brown K, Qiu X, Nabavi N, Mohrin M, Wojnoonski K, Li P, Cheng HL, Murphy AJ, Valenzuela DM, Luo H, Kapahi P, Krauss R, Mostoslavsky R, Yancopoulos GD, Alt FW, Chua KF, Chen D.
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| Cell Rep 5(3):654-65. doi: 10.1016/j.celrep.2013.10.007. Epub 2013 Nov 7. Erratum in: Cell Rep. 2013 Dec 12;5(5):1479.
2013
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| 13 | MYBBP1A, SIRT7
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| Inhibition of H3K18 deacetylation of Sirt7 by Myb-binding protein 1a (Mybbp1a).
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| Karim MF, Yoshizawa T, Sato Y, Sawa T, Tomizawa K, Akaike T, Yamagata K.
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| Biochem Biophys Res Commun 441(1):157-63. doi: 10.1016/j.bbrc.2013.10.020. Epub 2013 Oct 14.
2013
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| 14 | SIRT7
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| Sirtuin-7 inhibits the activity of hypoxia-inducible factors.
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| Hubbi ME, Hu H, Kshitiz, Gilkes DM, Semenza GL.
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| J Biol Chem 288(29):20768-75. doi: 10.1074/jbc.M113.476903. Epub 2013 Jun 9.
2013
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| 15 | SIRT7
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| Intracellular distribution of human SIRT7 and mapping of the nuclear/nucleolar localization signal.
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| Kiran S, Chatterjee N, Singh S, Kaul SC, Wadhwa R, Ramakrishna G.
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| FEBS J 280(14):3451-66. doi: 10.1111/febs.12346. Epub 2013 Jun 20.
2013
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| 16 | ELK4, SIRT7
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| SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.
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| Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF.
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| Nature 487(7405):114-8. doi: 10.1038/nature11043.
2012
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| 17 | SIRT7
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| Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis.
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| Grob A, Roussel P, Wright JE, McStay B, Hernandez-Verdun D, Sirri V.
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| J Cell Sci 122(Pt 4):489-98. doi: 10.1242/jcs.042382. Epub 2009 Jan 27.
2009
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| 18 | SIRT7
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| Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging.
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| Vakhrusheva O, Braeuer D, Liu Z, Braun T, Bober E.
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| J Physiol Pharmacol 59 Suppl 9:201-12.
2008
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| 19 | SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7, SIRT8
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| Sirtuins: critical regulators at the crossroads between cancer and aging.
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| Saunders LR, Verdin E.
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| Oncogene 26(37):5489-504. Review.
2007
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| 20 | SIRT7
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| Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription.
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| Ford E, Voit R, Liszt G, Magin C, Grummt I, Guarente L.
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| Genes Dev 20(9):1075-80. Epub 2006 Apr 17. 2006
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| 21 | SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7
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| Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.
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| Araki T, Sasaki Y, Milbrandt J.
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| Science 305(5686):1010-3. 2004
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| 22 | SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7
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| Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins.
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| Frye RA.
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| Biochem Biophys Res Commun 273(2):793-8. 2000
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| 23 | SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7
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| Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.
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| Frye RA.
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| Biochem Biophys Res Commun 260(1):273-9. 1999
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