Citations for
1SIRT3, SIRT4, SIRT5
Mitochondrial Sirtuins in Skin and Skin Cancers.
Su S, Ndiaye M, Singh CK, Ahmad N.
Photochem Photobiol hotochem Photobiol. 2020 Mar 3. doi: 10.1111/php.13254. [Epub ahead of print] Review. 2020
2SIRT4
Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer.
Tomaselli D, Steegborn C, Mai A, Rotili D.
Front Oncol 10:474. doi: 10.3389/fonc.2020.00474. eCollection 2020. Review. 2020
3SIRT3, SIRT4, SIRT5
Sirt4 Modulates Oxidative Metabolism and Sensitivity to Rapamycin Through Species-Dependent Phenotypes in Drosophila mtDNA Haplotypes.
Sejour R, Sanguino RA, Mikolajczak M, Ahmadi W, Villa-Cuesta E.
G3 (Bethesda) 10(5):1599-1612. doi: 10.1534/g3.120.401174. 2020
4SIRT4
Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria.
Shaw E, Talwadekar M, Rashida Z, Mohan N, Acharya A, Khatri S, Laxman S, Kolthur-Seetharam U.
Mol Cell Biol 40(2). pii: e00212-19. doi: 10.1128/MCB.00212-19. Print 2020 Jan 3. 2020
5SIRT4
SIRT4 silencing in tumor-associated macrophages promotes HCC development via PPARδ signalling-mediated alternative activation of macrophages.
Li Z, Li H, Zhao ZB, Zhu W, Feng PP, Zhu XW, Gong JP.
J Exp Clin Cancer Res 38(1):469. doi: 10.1186/s13046-019-1456-9. 2019
6SIRT4
SIRT4 is the last puzzle of mitochondrial sirtuins.
Li Y, Zhou Y, Wang F, Chen X, Wang C, Wang J, Liu T, Li Y, He B.
Bioorg Med Chem 26(14):3861-3865. doi: 10.1016/j.bmc.2018.07.031. Epub 2018 Jul 19. Review. 2018
7SIRT4
SIRT4 is essential for metabolic control and meiotic structure during mouse oocyte maturation.
Zeng J, Jiang M, Wu X, Diao F, Qiu D, Hou X, Wang H, Li L, Li C, Ge J, Liu J, Ou X, Wang Q.
Aging Cell 17(4):e12789. doi: 10.1111/acel.12789. Epub 2018 May 29. 2018
8OPA1, SIRT4
SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy.
Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP.
Aging (Albany NY) 9(10):2163-2189. doi: 10.18632/aging.101307. Erratum in: Aging (Albany NY). 2018 Sep 28;10(9):2536c. 2017
9SIRT4
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.
Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD.
Cell Metab 25(4):838-855.e15. doi: 10.1016/j.cmet.2017.03.003. 2017
10SIRT4
HELLP Syndrome.
Sandvoß M, Potthast AB, von Versen-Höynck F, Das AM.
Reprod Sci 24(4):568-574. doi: 10.1177/1933719116667216. Epub 2016 Sep 27. 2017
11SIRT4
SIRT4 regulates cancer cell survival and growth after stress.
Jeong SM, Hwang S, Seong RH.
Biochem Biophys Res Commun 470(2):251-256. doi: 10.1016/j.bbrc.2016.01.078. Epub 2016 Jan 14. 2016
12SIRT4
Tumour-suppressive function of SIRT4 in human colorectal cancer.
Miyo M, Yamamoto H, Konno M, Colvin H, Nishida N, Koseki J, Kawamoto K, Ogawa H, Hamabe A, Uemura M, Nishimura J, Hata T, Takemasa I, Mizushima T, Doki Y, Mori M, Ishii H.
Br J Cancer 113(3):492-9. doi: 10.1038/bjc.2015.226. Epub 2015 Jun 18. 2015
13CTBP1, SIRT4
CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4.
Wang L, Zhou H, Wang Y, Cui G, Di LJ.
Cell Death Dis 6:e1620. doi: 10.1038/cddis.2014.587. 2015
14SIRT4
Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity.
Mathias RA, Greco TM, Oberstein A, Budayeva HG, Chakrabarti R, Rowland EA, Kang Y, Shenk T, Cristea IM.
Cell 159(7):1615-25. doi: 10.1016/j.cell.2014.11.046. 2014
15SIRT4, SLC25A5
SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK.
Ho L, Titus AS, Banerjee KK, George S, Lin W, Deota S, Saha AK, Nakamura K, Gut P, Verdin E, Kolthur-Seetharam U.
Aging (Albany NY) 5(11):835-49. 2013
16MLYCD, SIRT4
SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase.
Laurent G, German NJ, Saha AK, de Boer VC, Davies M, Koves TR, Dephoure N, Fischer F, Boanca G, Vaitheesvaran B, Lovitch SB, Sharpe AH, Kurland IJ, Steegborn C, Gygi SP, Muoio DM, Ruderman NB, Haigis MC.
Mol Cell 50(5):686-98. doi: 10.1016/j.molcel.2013.05.012. 2013
17GLUD1, SIRT4
Glutamate dehydrogenase 1 and SIRT4 regulate glial development.
Komlos D, Mann KD, Zhuo Y, Ricupero CL, Hart RP, Liu AY, Firestein BL.
Glia 61(3):394-408. doi: 10.1002/glia.22442. Epub 2012 Dec 22. 2013
18SIRT1, SIRT4
The expression of Sirtuins 1 and 4 in peripheral blood leukocytes from patients with type 2 diabetes.
Song R, Xu W, Chen Y, Li Z, Zeng Y, Fu Y.
Eur J Histochem 55(1):e10. doi: 10.4081/ejh.2011.e10. 2011
19MRPL10, SIRT3, SIRT4
NAD+-dependent deacetylase SIRT3 regulates mitochondrial protein synthesis by deacetylation of the ribosomal protein MRPL10.
Yang Y, Cimen H, Han MJ, Shi T, Deng JH, Koc H, Palacios OM, Montier L, Bai Y, Tong Q, Koc EC.
J Biol Chem 285(10):7417-29. Epub 2009 Dec 30.PMID: 20042612 2010
20SIRT4
SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells.
Nasrin N, Wu X, Fortier E, Feng Y, Bare' OC, Chen S, Ren X, Wu Z, Streeper RS, Bordone L.
J Biol Chem 285(42):31995-2002. Epub 2010 Aug 4. 2010
21SIRT4
Fluorescence in situ hybridization and chromosomal organization of the sirtuin 4 gene (Sirt4) in the mouse.
Mahlknecht U, Voelter-Mahlknecht S.
Biochem Biophys Res Commun 382(4):685-90. Epub 2009 Mar 21. 2009
22SIRT3, SIRT4, SIRT5
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.
Schlicker C, Gertz M, Papatheodorou P, Kachholz B, Becker CF, Steegborn C.
J Mol Biol 382(3):790-801. Epub 2008 Jul 25. 2008
23SIRT3, SIRT4, SIRT5
Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5.
Nakamura Y, Ogura M, Tanaka D, Inagaki N.
Biochem Biophys Res Commun 366(1):174-9. Epub 2007 Dec 3. 2008
24SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7, SIRT8
Sirtuins: critical regulators at the crossroads between cancer and aging.
Saunders LR, Verdin E.
Oncogene 26(37):5489-504. Review. 2007
25SIRT4, SLC25A5
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase.
Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P, Verdin E.
J Biol Chem 282(46):33583-92. Epub 2007 Aug 22. 2007
26SIRT4, GLUD1
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.
Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJ, Valenzuela DM, Yancopoulos GD, Karow M, Blander G, Wolberger C, Prolla TA, Weindruch R, Alt FW, Guarente L.
Cell 126(5):941-54. 2006
27SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.
Araki T, Sasaki Y, Milbrandt J.
Science 305(5686):1010-3. 2004
28SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins.
Frye RA.
Biochem Biophys Res Commun 273(2):793-8. 2000
29SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.
Frye RA.
Biochem Biophys Res Commun 260(1):273-9. 1999