| 1 | EZH2, SIN3A, TET1, TET2
|
| Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination
|
| Cakouros D, Hemming S, Gronthos K, Liu R, Zannettino A, Shi S, Gronthos S.
|
| Epigenetics Chromatin. Jan 3;12(1):3. doi: 10.1186/s13072-018-0247-4. 2019
|
| 2 | SIN3A
|
| The Transcriptional Corepressor SIN3 Directly Regulates Genes Involved in Methionine Catabolism and Affects Histone Methylation, Linking Epigenetics and Metabolism.
|
| Liu M, Pile LA.
|
| J Biol Chem Biol Chem. 2016 Dec 27. pii: jbc.M116.749754. doi: 10.1074/jbc.M116.749754. [Epub ahead of print]
2016
|
| 3 | SIN3A, SIN3B
|
| SIN3A and SIN3B differentially regulate breast cancer metastasis.
|
| Lewis MJ, Liu J, Libby EF, Lee M, Crawford NP, Hurst DR.
|
| Oncotarget 7(48):78713-78725. doi: 10.18632/oncotarget.12805.
2016
|
| 4 | HDAC1, SIN3A, TET3
|
| TET3 Inhibits Type I IFN Production Independent of DNA Demethylation.
|
| Xue S, Liu C, Sun X, Li W, Zhang C, Zhou X, Lu Y, Xiao J, Li C, Xu X, Sun B, Xu G, Wang H.
|
| Cell Rep 16(4):1096-105. doi: 10.1016/j.celrep.2016.06.068.
2016
|
| 5 | PHF12, SIN3A
|
| Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer.
|
| Bansal N, Petrie K, Christova R, Chung CY, Leibovitch BA, Howell L, Gil V, Sbirkov Y, Lee E, Wexler J, Ariztia EV, Sharma R, Zhu J, Bernstein E, Zhou MM, Zelent A, Farias E, Waxman S.
|
| Oncotarget 6(33):34087-105. doi: 10.18632/oncotarget.6048.
2015
|
| 6 | SIN3A
|
| SIN3A mutations are rare in men with azoospermia.
|
| Miyamoto T, Koh E, Tsujimura A, Miyagawa Y, Minase G, Ueda Y, Namiki M, Sengoku K.
|
| Andrologia 47(9):1083-5. doi: 10.1111/and.12379.
2015
|
| 7 | CYP1A1, SIN3A
|
| SIN3A, generally regarded as a transcriptional repressor, is required for induction of gene transcription by the aryl hydrocarbon receptor.
|
| Solaimani P, Wang F, Hankinson O.
|
| J Biol Chem 289(48):33655-62. doi: 10.1074/jbc.M114.611236.
2014
|
| 8 | SIN3A
|
| Whole-genome analysis of muscle founder cells implicates the chromatin regulator Sin3A in muscle identity.
|
| Dobi KC, Halfon MS, Baylies MK.
|
| Cell Rep 8(3):858-70. doi: 10.1016/j.celrep.2014.07.005.
2014
|
| 9 | HDAC1, HDAC2, SIN3A
|
| Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis.
|
| Heideman MR, Lancini C, Proost N, Yanover E, Jacobs H, Dannenberg JH.
|
| Haematologica 99(8):1292-303. doi: 10.3324/haematol.2013.092643.
2014
|
| 10 | SIN3A
|
| Distinct requirements for Sin3a in perinatal male gonocytes and differentiating spermatogonia.
|
| Gallagher SJ, Kofman AE, Huszar JM, Dannenberg JH, DePinho RA, Braun RE, Payne CJ.
|
| Dev Biol 373(1):83-94. doi: 10.1016/j.ydbio.2012.10.009.
2013
|
| 11 | FOXK1, SIN3A, SIN3B
|
| Sin3 interacts with Foxk1 and regulates myogenic progenitors.
|
| Shi X, Garry DJ.
|
| Mol Cell Biochem 366(1-2):251-8. Epub 2012 Apr 4.
2012
|
| 12 | IGSF3, SIN3A, STAT3
|
| The Sin3a repressor complex is a master regulator of STAT transcriptional activity.
|
| Icardi L, Mori R, Gesellchen V, Eyckerman S, De Cauwer L, Verhelst J, Vercauteren K, Saelens X, Meuleman P, Leroux-Roels G, De Bosscher K, Boutros M, Tavernier J.
|
| Proc Natl Acad Sci U S A 109(30):12058-63. doi: 10.1073/pnas.1206458109. Epub 2012 Jul 10.
2012
|
| 13 | CDH6, PHF12, SIN3A, SNAI2
|
| A PHD12-Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition.
|
| Strobl-Mazzulla PH, Bronner ME.
|
| J Cell Biol 198(6):999-1010. doi: 10.1083/jcb.201203098.
2012
|
| 14 | CCND1, FAM60A, HDAC1, SIN3A
|
| Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.
|
| Muņoz IM, MacArtney T, Sanchez-Pulido L, Ponting CP, Rocha S, Rouse J.
|
| J Biol Chem 287(39):32346-53.
2012
|
| 15 | GFAP, SIN3A
|
| Interplay between SIN3A and STAT3 mediates chromatin conformational changes and GFAP expression during cellular differentiation.
|
| Cheng PY, Lin YP, Chen YL, Lee YC, Tai CC, Wang YT, Chen YJ, Kao CF, Yu J.
|
| PLoS One 6(7):e22018. Epub 2011 Jul 11.
2011
|
| 16 | SAP30, SIN3A
|
| Structure of the 30-kDa Sin3-associated protein (SAP30) in complex with the mammalian Sin3A corepressor and its role in nucleic acid binding.
|
| Xie T, He Y, Korkeamaki H, Zhang Y, Imhoff R, Lohi O, Radhakrishnan I.
|
| J Biol Chem 286(31):27814-24. Epub 2011 Jun 15.
2011
|
| 17 | SIN3A, SIN3B
|
| Tumor suppressor protein p53 recruits human Sin3B/HDAC1 complex for down-regulation of its target promoters in response to genotoxic stress.
|
| Bansal N, Kadamb R, Mittal S, Vig L, Sharma R, Dwarakanath BS, Saluja D.
|
| PLoS One 6(10):e26156. doi: 10.1371/journal.pone.0026156.
2011
|
| 18 | ING2, SIN3A, SPP1, TMEM71
|
| Sumoylation of ING2 regulates the transcription mediated by Sin3A.
|
| Ythier D, Larrieu D, Binet R, Binda O, Brambilla C, Gazzeri S, Pedeux R.
|
| Oncogene 29(44):5946-56. Epub 2010 Aug 2.
2010
|
| 19 | SIN3A, SIN3B
|
| The mammalian Sin3 proteins are required for muscle development and sarcomere specification.
|
| van Oevelen C, Bowman C, Pellegrino J, Asp P, Cheng J, Parisi F, Micsinai M, Kluger Y, Chu A, Blais A, David G, Dynlacht BD.
|
| Mol Cell Biol 30(24):5686-97. doi: 10.1128/MCB.00975-10.
2010
|
| 20 | ESR1, SIN3A
|
| Repression of ESR1 through actions of estrogen receptor alpha and Sin3A at the proximal promoter.
|
| Ellison-Zelski SJ, Solodin NM, Alarid ET.
|
| Mol Cell Biol 29(18):4949-58. Epub 2009 Jul 20.
2009
|
| 21 | NFX1, SIN3A, TERT
|
| NFX1 interacts with mSin3A/histone deacetylase to repress hTERT transcription in keratinocytes.
|
| Xu M, Luo W, Elzi DJ, Grandori C, Galloway DA.
|
| Mol Cell Biol 28(15):4819-28. Epub 2008 May 27.
2008
|
| 22 | SIN3A
|
| Drosophila SIN3 is required at multiple stages of development.
|
| Sharma V, Swaminathan A, Bao R, Pile LA.
|
| Dev Dyn 237(10):3040-50.
2008
|
| 23 | PRMT1, RUNX1, SIN3A
|
| Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity.
|
| Zhao X, Jankovic V, Gural A, Huang G, Pardanani A, Menendez S, Zhang J, Dunne R, Xiao A, Erdjument-Bromage H, Allis CD, Tempst P, Nimer SD.
|
| Genes Dev 22(5):640-53.
2008
|
| 24 | SIN3A
|
| Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription.
|
| Yao D, Taguchi T, Matsumura T, Pestell R, Edelstein D, Giardino I, Suske G, Ahmed N, Thornalley PJ, Sarthy VP, Hammes HP, Brownlee M.
|
| Cell 124(2):275-86. Epub 2006 Jan 12. 2006
|
| 25 | SAP30, SAP30L, SIN3A
|
| SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus.
|
| Viiri KM, Korkeamaki H, Kukkonen MK, Nieminen LK, Lindfors K, Peterson P, Maki M, Kainulainen H, Lohi O.
|
| Nucleic Acids Res 34(11):3288-98. Print 2006. 2006
|
| 26 | SIN3A, SMN1
|
| Survival motor neuron (SMN) protein interacts with transcription corepressor mSin3A.
|
| Zou J, Barahmand-pour F, Blackburn ML, Matsui Y, Chansky HA, Yang L.
|
| J Biol Chem 279(15):14922-8. Epub 2004 Jan 28. 2004
|
| 27 | ARID4B, SAP130, SIN3A
|
| Identification and characterization of three new components of the mSin3A corepressor complex.
|
| Fleischer TC, Yun UJ, Ayer DE.
|
| Mol Cell Biol 23(10):3456-67. 2003
|
| 28 | ATRX, DNMT1, DNMT3B, HDAC1, HDAC2, KAT2B, KAT8, MBD1, MBD2, MECP2, SIN3A
|
| Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.
|
| Craig JM, Earle E, Canham P, Wong LH, Anderson M, Choo KH.
|
| Hum Mol Genet 12(23):3109-21. Epub 2003 Sep 30. 2003
|
| 29 | MORF4L1, PHF12, SIN3A
|
| Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split.
|
| Yochum GS, Ayer DE.
|
| Mol Cell Biol 22(22):7868-76.PMID: 12391155 2002
|
| 30 | SAP18,SIN3A
|
| Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex.
|
| Zhang Y, Iratni R, Erdjument-Bromage H, Tempst P, Reinberg D.
|
| Cell 89(3):357-64. 1997
|
| 31 | SIN3A, SIN3B
|
| A widely distributed putative mammalian transcriptional regulator containing multiple paired amphipathic helices, with similarity to yeast SIN3.
|
| Halleck MS, Pownall S, Harder KW, Duncan AM, Jirik FR, Schlegel RA.
|
| Genomics 26(2):403-6. 1995
|
| 32 | SIN3A, SIN3B
|
| Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3.
|
| Ayer DE, Lawrence QA, Eisenman RN.
|
| Cell 80(5):767-76. 1995
|