| 1 | SIK3
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| Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
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| Yahara Y, Takemori H, Okada M, Kosai A, Yamashita A, Kobayashi T, Fujita K, Itoh Y, Nakamura M, Fuchino H, Kawahara N, Fukui N, Watanabe A, Kimura T, Tsumaki N.
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| Nat Commun 7:10959. doi: 10.1038/ncomms10959.
2016
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| 2 | SIK1, SIK2, SIK3
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| Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes.
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| Itoh Y, Sanosaka M, Fuchino H, Yahara Y, Kumagai A, Takemoto D, Kagawa M, Doi J, Ohta M, Tsumaki N, Kawahara N, Takemori H.
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| J Biol Chem 290(29):17879-93. doi: 10.1074/jbc.M115.640821. Epub 2015 Jun 5.
2015
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| 3 | SIK3
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| Salt-inducible kinase 3 deficiency exacerbates lipopolysaccharide-induced endotoxin shock accompanied by increased levels of pro-inflammatory molecules in mice.
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| Sanosaka M, Fujimoto M, Ohkawara T, Nagatake T, Itoh Y, Kagawa M, Kumagai A, Fuchino H, Kunisawa J, Naka T, Takemori H.
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| Immunology 145(2):268-78. doi: 10.1111/imm.12445.
2015
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| 4 | SIK3, STK11
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| Feeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in Drosophila.
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| Choi S, Lim DS, Chung J.
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| PLoS Genet 11(5):e1005263. doi: 10.1371/journal.pgen.1005263. eCollection 2015 May.
2015
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| 5 | SIK1, SIK2, SIK3, STK11
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| The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.
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| Patel K, Foretz M, Marion A, Campbell DG, Gourlay R, Boudaba N, Tournier E, Titchenell P, Peggie M, Deak M, Wan M, Kaestner KH, Göransson O, Viollet B, Gray NS, Birnbaum MJ, Sutherland C, Sakamoto K.
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| Nat Commun 5:4535. doi: 10.1038/ncomms5535.
2014
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| 6 | SIK3
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| Salt-inducible kinase 3, SIK3, is a new gene associated with hearing.
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| Wolber LE, Girotto G, Buniello A, Vuckovic D, Pirastu N, Lorente-Cánovas B, Rudan I, Hayward C, Polasek O, Ciullo M, Mangino M, Steves C, Concas MP, Cocca M, Spector TD, Gasparini P, Steel KP, Williams FM.
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| Hum Mol Genet 23(23):6407-18. doi: 10.1093/hmg/ddu346. Epub 2014 Jul 24.
2014
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| 7 | SIK3
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| Salt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death.
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| Chen H, Huang S, Han X, Zhang J, Shan C, Tsang YH, Ma HT, Poon RY.
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| Cell Death Dis 5:e1177. doi: 10.1038/cddis.2014.154.
2014
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| 8 | SIK1, SIK3
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| Salt-inducible kinases 1 and 3 negatively regulate Toll-like receptor 4-mediated signal.
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| Yong Kim S, Jeong S, Chah KH, Jung E, Baek KH, Kim ST, Shim JH, Chun E, Lee KY.
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| Mol Endocrinol 27(11):1958-68. doi: 10.1210/me.2013-1240. Epub 2013 Sep 23.
2013
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| 9 | SIK2, SIK3, STK11
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| The tumor suppressor kinase LKB1 activates the downstream kinases SIK2 and SIK3 to stimulate nuclear export of class IIa histone deacetylases.
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| Walkinshaw DR, Weist R, Kim GW, You L, Xiao L, Nie J, Li CS, Zhao S, Xu M, Yang XJ.
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| J Biol Chem 288(13):9345-62. doi: 10.1074/jbc.M113.456996. Epub 2013 Feb 7.
2013
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| 10 | SIK1, SIK3, TAB2, TLR4, TRAF6
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| Salt-inducible kinases 1 and 3 negatively regulate Toll-like receptor 4-mediated signal.
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| Yong Kim S, Jeong S, Chah KH, Jung E, Baek KH, Kim ST, Shim JH, Chun E, Lee KY.
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| Mol Endocrinol 27(11):1958-68. doi: 10.1210/me.2013-1240. Epub 2013 Sep 23. 2013
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| 11 | SIK3
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| Involvement of SIK3 in glucose and lipid homeostasis in mice.
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| Uebi T, Itoh Y, Hatano O, Kumagai A, Sanosaka M, Sasaki T, Sasagawa S, Doi J, Tatsumi K, Mitamura K, Morii E, Aozasa K, Kawamura T, Okumura M, Nakae J, Takikawa H, Fukusato T, Koura M, Nish M, Hamsten A, Silveira A, Bertorello AM, Kitagawa K, Nagaoka Y, Kawahara H, Tomonaga T, Naka T, Ikegawa S, Tsumaki N, Matsuda J, Takemori H.
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| PLoS One 7(5):e37803. doi: 10.1371/journal.pone.0037803. Epub 2012 May 25.
2012
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| 12 | SIK3
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| SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice.
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| Sasagawa S, Takemori H, Uebi T, Ikegami D, Hiramatsu K, Ikegawa S, Yoshikawa H, Tsumaki N.
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| Development 139(6):1153-63. doi: 10.1242/dev.072652. Epub 2012 Feb 8.
2012
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| 13 | SIK3
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| Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer.
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| Charoenfuprasert S, Yang YY, Lee YC, Chao KC, Chu PY, Lai CR, Hsu KF, Chang KC, Chen YC, Chen LT, Chang JY, Leu SJ, Shih NY.
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| Oncogene 30(33):3570-84. doi: 10.1038/onc.2011.77. Epub 2011 Mar 14.
2011
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| 14 | SIK1, SIK2, SIK3
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| Salt-inducible kinase (SIK) isoforms: their involvement in steroidogenesis and adipogenesis.
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| Katoh Y, Takemori H, Horike N, Doi J, Muraoka M, Min L, Okamoto M.
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| Mol Cell Endocrinol 217(1-2):109-12.
2004
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