Citations for
1SIGMAR1
Characterization of the human sigma-1 receptor chaperone domain structure and binding immunoglobulin protein (BiP) interactions.
Ortega-Roldan JL, Ossa F, Schnell JR.
J Biol Chem 288(29):21448-57. doi: 10.1074/jbc.M113.450379. Epub 2013 Jun 12. 2013
2IL24, SIGMAR1
Sigma 1 Receptor plays a prominent role in IL-24-induced cancer-specific apoptosis.
Do W, Herrera C, Mighty J, Shumskaya M, Redenti SM, Sauane M.
Biochem Biophys Res Commun 439(2):215-20. doi: 10.1016/j.bbrc.2013.08.057. Epub 2013 Aug 26. 2013
3SIGMAR1
Lack of sigma-1 receptor exacerbates ALS progression in mice.
Mavlyutov TA, Epstein ML, Verbny YI, Huerta MS, Zaitoun I, Ziskind-Conhaim L, Ruoho AE.
Neuroscience 240:129-34. doi: 10.1016/j.neuroscience.2013.02.035. Epub 2013 Feb 28. 2013
4ALS16, SIGMAR1
Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis.
Prause J, Goswami A, Katona I, Roos A, Schnizler M, Bushuven E, Dreier A, Buchkremer S, Johann S, Beyer C, Deschauer M, Troost D, Weis J.
Hum Mol Genet 22(8):1581-600. doi: 10.1093/hmg/ddt008. Epub 2013 Jan 11. 2013
5SIGMAR1
The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements.
Pal A, Fontanilla D, Gopalakrishnan A, Chae YK, Markley JL, Ruoho AE.
Eur J Pharmacol 682(1-3):12-20. doi: 10.1016/j.ejphar.2012.01.030. Epub 2012 Feb 22. 2012
6ADAM10, ADAM17, SIGMAR1
Overexpression of sigma-1 receptor inhibits ADAM10 and ADAM17 mediated shedding in vitro.
Li J, Liu B, Gao X, Ma Z, CaoSong T, Mei YA, Zheng Y.
Protein Cell 3(2):153-9. doi: 10.1007/s13238-012-2006-9. Epub 2012 Feb 9. Erratum in: Protein Cell. 2012 May;3(5):400. 2012
7SIGMAR1
Expression of a truncated form of the endoplasmic reticulum chaperone protein, σ1 receptor, promotes mitochondrial energy depletion and apoptosis.
Shioda N, Ishikawa K, Tagashira H, Ishizuka T, Yawo H, Fukunaga K.
J Biol Chem 287(28):23318-31. doi: 10.1074/jbc.M112.349142. Epub 2012 May 22. 2012
8ALS16, SIGMAR1
A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis.
Al-Saif A, Al-Mohanna F, Bohlega S.
Ann Neurol 70(6):913-9. doi: 10.1002/ana.22534. Epub 2011 Aug 12. 2011
9ALS16, SIGMAR1
SIGMAR1 mutations, genetic heterogeneity at the chromosome 9p locus, and the expanding etiological diversity of amyotrophic lateral sclerosis.
Fecto F, Siddique T.
Ann Neurol 70(6):867-70. doi: 10.1002/ana.22648. No abstract available. 2011
10SIGMAR1
Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1).
Ha Y, Saul A, Tawfik A, Williams C, Bollinger K, Smith R, Tachikawa M, Zorrilla E, Ganapathy V, Smith SB.
Invest Ophthalmol Vis Sci 52(10):7749-60. doi: 10.1167/iovs.11-8169. 2011
11HSPA5, SIGMAR1, SRR
Sigma receptor 1 modulates endoplasmic reticulum stress in retinal neurons.
Ha Y, Dun Y, Thangaraju M, Duplantier J, Dong Z, Liu K, Ganapathy V, Smith SB.
Invest Ophthalmol Vis Sci 52(1):527-40. doi: 10.1167/iovs.10-5731. Print 2011 Jan. 2011
12SIGMAR1
Expression of sigma receptor 1 mRNA and protein in rat retina.
Liu LL, Wang L, Zhong YM, Yang XL.
Neuroscience 167(4):1151-9. doi: 10.1016/j.neuroscience.2010.03.006. Epub 2010 Mar 9. 2010
13DRD1, SIGMAR1
Sigma-1 receptors amplify dopamine D1 receptor signaling at presynaptic sites in the prelimbic cortex.
Fu Y, Zhao Y, Luan W, Dong LY, Dong Y, Lai B, Zhu Y, Zheng P.
Biochim Biophys Acta 1803(12):1396-408. doi: 10.1016/j.bbamcr.2010.08.005. Epub 2010 Aug 20. 2010
14SIGMAR1
Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction.
Tchedre KT, Huang RQ, Dibas A, Krishnamoorthy RR, Dillon GH, Yorio T.
Invest Ophthalmol Vis Sci 49(11):4993-5002. doi: 10.1167/iovs.08-1867. Epub 2008 Jul 18. 2008
15SIGMAR1
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival.
Hayashi T, Su TP.
Cell 131(3):596-610. 2007
16SIGMAR1
Silencing of sigma-1 receptor induces cell death in human lens cells.
Wang L, Duncan G.
Exp Cell Res 312(8):1439-46. Epub 2006 Feb 9. 2006
17SIGMAR1
Immunohistochemical localization of the sigma1-receptor in oligodendrocytes in the rat central nervous system.
Palacios G, Muro A, Vela JM, Molina-Holgado E, Guitart X, Ovalle S, Zamanillo D.
Brain Res 961(1):92-9. 2003
18SIGMAR1
Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina
Shamsul Ola M, Moore P, El-Sherbeny A, Roon P, Agarwal N, Sarthy VP, Casellas P, Ganapathy V, Smith SB.
Brain Res Mol Brain Res 95(1-2):86-95. 2001
19DEL3PD, SIGMAR1
Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene
Prasad PD, Li HW, Fei YJ, Ganapathy ME, Fujita T, Plumley LH, Yang-Feng TL, Leibach FH, Ganapathy V.
J Neurochem 70(2):443-51. 1998
20SIGMAR1
Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1)
Kekuda R, Prasad PD, Fei YJ, Leibach FH, Ganapathy V.
Biochem Biophys Res Commun 229(2):553-8. 1996
21SIGMAR1
41.
The SIGMAR1 gene is associated with a risk of schizophrenia and activation of the prefrontal cortex.
Ohi K, Hashimoto R, Yasuda Y, Fukumoto M, Yamamori H, Umeda-Yano S, Kamino K, Ikezawa K, Azechi M, Iwase M, Kazui H, Kasai K, Ta hi K, Hashimoto R, Yasuda Y, Fukumoto M, Yamamori H, Umeda-Yano S, Kamino K, Ikezawa K, Azechi M, Iwase M, Kazui H, Kasai K, Tak