Citations for
1KIT, SH3BP2
The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival.
Ainsua-Enrich E, Serrano-Candelas E, Álvarez-Errico D, Picado C, Sayós J, Rivera J, Martín M.
J Immunol 194(9):4309-18. doi: 10.4049/jimmunol.1402887. Epub 2015 Mar 25. 2015
2CRBM, SH3BP2
Enhanced TLR-MYD88 signaling stimulates autoinflammation in SH3BP2 cherubism mice and defines the etiology of cherubism.
Yoshitaka T, Mukai T, Kittaka M, Alford LM, Masrani S, Ishida S, Yamaguchi K, Yamada M, Mizuno N, Olsen BR, Reichenberger EJ, Ueki Y.
Cell Rep 8(6):1752-66. doi: 10.1016/j.celrep.2014.08.023. Epub 2014 Sep 15. 2014
3SH3BP2
SH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis model.
Mukai T, Gallant R, Ishida S, Yoshitaka T, Kittaka M, Nishida K, Fox DA, Morita Y, Ueki Y.
PLoS One 9(8):e105518. doi: 10.1371/journal.pone.0105518. eCollection 2014. 2014
4SH3BP2
SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.
Mukai T, Ishida S, Ishikawa R, Yoshitaka T, Kittaka M, Gallant R, Lin YL, Rottapel R, Brotto M, Reichenberger EJ, Ueki Y.
J Bone Miner Res 29(12):2618-35. doi: 10.1002/jbmr.2295. 2014
5SH3BP2
The adaptor 3BP2 is required for early and late events in FcεRI signaling in human mast cells.
Ainsua-Enrich E, Alvarez-Errico D, Gilfillan AM, Picado C, Sayós J, Rivera J, Martín M.
J Immunol 189(6):2727-34. doi: 10.4049/jimmunol.1200380. Epub 2012 Aug 15. 2012
6PARP1, SH3BP2
Cloning and characterization of the human SH3BP2 promoter.
Fan C, Gaivin RJ, Marth TA, Willard B, Levine MA, Lietman SA.
Biochem Biophys Res Commun 425(1):25-32. doi: 10.1016/j.bbrc.2012.07.043. Epub 2012 Jul 17. 2012
7SH3BP2
The 3BP2 adapter protein is required for chemoattractant-mediated neutrophil activation.
Chen G, Dimitriou I, Milne L, Lang KS, Lang PA, Fine N, Ohashi PS, Kubes P, Rottapel R.
J Immunol 189(5):2138-50. doi: 10.4049/jimmunol.1103184. Epub 2012 Jul 18. 2012
8PTPN6, SH3BP2
Association of 3BP2 with SHP-1 regulates SHP-1-mediated production of TNF-α in RBL-2H3 cells.
Chihara K, Nakashima K, Takeuchi K, Sada K.
Genes Cells 16(12):1133-45. doi: 10.1111/j.1365-2443.2011.01557.x. Epub 2011 Nov 13. 2011
9CRBM, RNF146, SH3BP2, TNKS, TNKS2
Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism.
Levaot N, Voytyuk O, Dimitriou I, Sircoulomb F, Chandrakumar A, Deckert M, Krzyzanowski PM, Scotter A, Gu S, Janmohamed S, Cong F, Simoncic PD, Ueki Y, La Rose J, Rottapel R.
Cell 147(6):1324-39. doi: 10.1016/j.cell.2011.10.045. 2011
10SH3BP2
3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functions.
Levaot N, Simoncic PD, Dimitriou ID, Scotter A, La Rose J, Ng AH, Willett TL, Wang CJ, Janmohamed S, Grynpas M, Reichenberger E, Rottapel R.
J Clin Invest 121(8):3244-57. doi: 10.1172/JCI45843. Epub 2011 Jul 18. 2011
11SH3BP2
Decreased SH3BP2 inhibits osteoclast differentiation and function.
Kawamoto T, Fan C, Gaivin RJ, Levine MA, Lietman SA.
J Orthop Res 29(10):1521-7. doi: 10.1002/jor.21408. Epub 2011 Mar 29. 2011
12SH3BP2
Cherubism gene Sh3bp2 is important for optimal bone formation, osteoblast differentiation, and function.
Mukherjee PM, Wang CJ, Chen IP, Jafarov T, Olsen BR, Ueki Y, Reichenberger EJ.
Am J Orthod Dentofacial Orthop 138(2):140.e1-140.e11; discussion 140-1. doi: 10.1016/j.ajodo.2009.05.021. 2010
13NFATC1, SH3BP2
Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT.
Shukla U, Hatani T, Nakashima K, Ogi K, Sada K.
J Biol Chem 284(49):33719-28. doi: 10.1074/jbc.M109.049999. Epub 2009 Oct 15. 2009
14CRBM, SH3BP2
Novel mutations in the SH3BP2 gene associated with sporadic central giant cell lesions and cherubism.
Carvalho VM, Perdigão PF, Amaral FR, de Souza PE, De Marco L, Gomez RS.
Oral Dis 15(1):106-10. doi: 10.1111/j.1601-0825.2008.01499.x. Epub 2008 Nov 11. 2009
15SH3BP2, CRBM
SH3BP2 is an activator of NFAT activity and osteoclastogenesis.
Lietman SA, Yin L, Levine MA.
Biochem Biophys Res Commun 371(4):644-8. Epub 2008 Apr 25. 2008
16DBNL, SH3BP2
Abl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55.
Le Bras S, Moon C, Foucault I, Breittmayer JP, Deckert M.
FEBS Lett 581(5):967-74. Epub 2007 Feb 8. 2007
17CRBM, SH3BP2
Novel mutation in the gene encoding c-Abl-binding protein SH3BP2 causes cherubism.
Lo B, Faiyaz-Ul-Haque M, Kennedy S, Aviv R, Tsui LC, Teebi AS.
Am J Med Genet 121A(1):37-40. 2003
18CRBM, SH3BP2
Mutations in the gene encoding c-Abl-binding protein SH3BP2 cause cherubism.
Ueki Y, Tiziani V, Santanna C, Fukai N, Maulik C, Garfinkle J, Ninomiya C, doAmaral C, Peters H, Habal M, Rhee-Morris L, Doss JB, Kreiborg S, Olsen BR, Reichenberger E.
Nat Genet 28(2):125-6. 2001
19CRBM, SH3BP2
The Gene for Cherubism Maps to Chromosome 4p16.
Tiziani V, et al.
Am J Hum Genet 65(1):158-166. 1999
20CRBM, SH3BP2
The gene for cherubism maps to chromosome 4p16.3.
Mangion J, Rahman N, Edkins S, Barfoot R, Nguyen T, Sigurdsson A, Townend JV, Fitzpatrick DR, Flanagan AM, Stratton MR.
Am J Hum Genet 65(1):151-7. 1999
21C4orf10, FAM193A, NOP14, RNF4, SH3BP2
The primary structure and genomic organization of five novel transcripts located close to the Huntington's disease gene on human chromosome 4p16.3.
Hadano S, Ishida Y, Ikeda JE.
DNA Res 5(3):177-86. 1998
22SH3BP2
Identification and characterization of the human homologue of SH3BP2, an SH3 binding domain protein within a common region of deletion at 4p16.3 involved in Bladder cancer.
Bell SM, Shaw M, Jou YS, Myers RM, Knowles MA.
Genomics 44(2):163-70. 1997
23ADD1, HGFAC, LRPAP1, SH3BP2
Exon trapping and sequence-based methods of gene finding in transcript mapping of human 4p16.3.
Pribill I, Barnes GT, Chen J, Church D, Buckler A, Baxendale S, Bates GP, Lehrach H, Gusella MJ, Duyao MP, Ambrose CM, Gusella JF, MacDonald ME.
Somat Cell Mol Genet 23 : 413-427. 1997
24LRPAP1, SH3BP2
Localization of the alpha2-macroglobulin receptor-associated protein 1 gene (LRPAP1) and other gene fragments to human chromosome 4p16.3 by direct cDNA selection.
Jou YS, et al.
Genomics 24 : 410-413. 1994