Citations for
1RGS1, SH2B3, TAGAP, TNFSF14
Presymptomatic Diagnosis of Celiac Disease in Predisposed Children: The Role of Gene Expression Profile.
Galatola M, Cielo D, Panico C, Stellato P, Malamisura B, Carbone L, Gianfrani C, Troncone R, Greco L, Auricchio R.
J Pediatr Gastroenterol Nutr 65(3):314-320. doi: 10.1097/MPG.0000000000001519. 2017
2IL7R, SH2B3
LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors.
Cheng Y, Chikwava K, Wu C, Zhang H, Bhagat A, Pei D, Choi JK, Tong W.
J Clin Invest 126(4):1267-81. doi: 10.1172/JCI81468. Epub 2016 Mar 14. 2016
3PDGFRB, SH2B3
Adaptor protein Lnk binds to PDGF receptor and inhibits PDGF-dependent signaling.
Gueller S, Hehn S, Nowak V, Gery S, Serve H, Brandts CH, Koeffler HP.
Exp Hematol 39(5):591-600. doi: 10.1016/j.exphem.2011.02.001. Epub 2011 Mar 1. 2011
4SH2B3
The carriage of the type 1 diabetes-associated R262W variant of human LNK correlates with increased proliferation of peripheral blood monocytes in diabetic patients.
Lavrikova EY, Nikitin AG, Kuraeva TL, Peterkova VA, Tsitlidze NM, Chistiakov DA, Nosikov VV.
Pediatr Diabetes ediatr Diabetes. 2010 Jun 7. [Epub ahead of print]PMID: 20546165 2010
5Sh2B3
Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection.
Zhernakova A, Elbers CC, Ferwerda B, Romanos J, Trynka G, Dubois PC, de Kovel CG, Franke L, Oosting M, Barisani D, Bardella MT; Finnish Celiac Disease Study Group, Joosten LA, Saavalainen P, van Heel DA, Catassi C, Netea MG, Wijmenga C.
Am J Hum Genet 86(6):970-7.PMID: 20560212 2010
6SH2B3
Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F.
Gery S, Cao Q, Gueller S, Xing H, Tefferi A, Koeffler HP.
J Leukoc Biol 85(6):957-65. Epub 2009 Mar 17.PMID: 19293402 2009
7SH2B3
Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals.
Takizawa H, Eto K, Yoshikawa A, Nakauchi H, Takatsu K, Takaki S.
Exp Hematol 36(7):897-906. Epub 2008 May 5.PMID: 18456388 2008
8SH2B3, TAGAP
Newly identified genetic risk variants for celiac disease related to the immune response.
Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, Gwilliam R, Takeuchi F, McLaren WM, Holmes GK, Howdle PD, Walters JR, Sanders DS, Playford RJ, Trynka G, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, O'Morain C, Kennedy NP, Kelleher D, Pennington DJ, Strachan DP, McArdle WL, Mein CA, Wapenaar MC, Deloukas P, McGinnis R, McManus R, Wijmenga C, van Heel DA.
Nat Genet 40(4):395-402. doi: 10.1038/ng.102. Epub 2008 Mar 2. 2008
9SH2B3
Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation.
Li Y, He X, Schembri-King J, Jakes S, Hayashi J.
J Immunol 164(10):5199-206. 2000
10FLNA, SH2B3
Identification of actin binding protein, ABP-280, as a binding partner of human Lnk adaptor protein.
He X, Li Y, Schembri-King J, Jakes S, Hayashi J.
Mol Immunol 37(10):603-12. 2000
11SH2B3
Characterization of Lnk. An adaptor protein expressed in lymphocytes.
Takaki S, Watts JD, Forbush KA, Nguyen NT, Hayashi J, Alberola-Ila J, Aebersold R, Perlmutter RM.
J Biol Chem 272(23):14562-70. 1997