| 1 | MTA1, SGK1
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| Cytoplasmic translocation of MTA1 coregulator promotes de-repression of SGK1 transcription in hypoxic cancer cells.
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| Marzook H, Deivendran S, George B, Reshmi G, Santhoshkumar TR, Kumar R, Pillai MR.
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| Oncogene 36(37):5263-5273. doi: 10.1038/onc.2017.19. Epub 2017 May 15.
2017
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| 2 | SGK1
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| Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress.
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| Licznerski P, Duric V, Banasr M, Alavian KN, Ota KT, Kang HJ, Jonas EA, Ursano R, Krystal JH, Duman RS; Traumatic Stress Brain Study Group.
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| PLoS Biol 13(10):e1002282. doi: 10.1371/journal.pbio.1002282. eCollection 2015 Oct.
2015
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| 3 | GRIK2, NDRG2, SGK1
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| NDRG2 phosphorylation provides negative feedback for SGK1-dependent regulation of a kainate receptor in astrocytes.
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| Matschke V, Theiss C, Hollmann M, Schulze-Bahr E, Lang F, Seebohm G, Strutz-Seebohm N.
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| Front Cell Neurosci 9:387. doi: 10.3389/fncel.2015.00387. eCollection 2015.
2015
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| 4 | AKT1, SGK1
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| Roles of Akt and SGK1 in the Regulation of Renal Tubular Transport.
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| Satoh N, Nakamura M, Suzuki M, Suzuki A, Seki G, Horita S.
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| Biomed Res Int 2015:971697. doi: 10.1155/2015/971697. Epub 2015 Sep 28. Review.
2015
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| 5 | CDKN1B, SGK1
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| SGK1-Sensitive Regulation of Cyclin-Dependent Kinase Inhibitor 1B (p27) in Cardiomyocyte Hypertrophy.
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| Voelkl J, Castor T, Musculus K, Viereck R, Mia S, Feger M, Alesutan I, Lang F.
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| Cell Physiol Biochem 37(2):603-614. [Epub ahead of print]
2015
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| 6 | DSG1C, SGK1
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| Sgk1 regulates desmoglein 1 expression levels in oligodendrocytes in the mouse corpus callosum after chronic stress exposure.
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| Miyata S, Yoshikawa K, Taniguchi M, Ishikawa T, Tanaka T, Shimizu S, Tohyama M.
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| Biochem Biophys Res Commun 464(1):76-82. doi: 10.1016/j.bbrc.2015.05.109. Epub 2015 Jun 1.
2015
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| 7 | NDRG1, SGK1
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| Serum- and glucocorticoid-inducible kinase 1 sensitive NF-κB signaling in dendritic cells.
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| Schmid E, Xuan NT, Zahir N, Russo A, Yang W, Kuhl D, Faggio C, Shumilina E, Lang F.
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| Cell Physiol Biochem 34(3):943-54. doi: 10.1159/000366311. Epub 2014 Aug 26.
2014
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| 8 | CTNNB1, SGK1
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| Serum and glucocorticoid-regulated kinase 1 promotes vascular smooth muscle cell proliferation via regulation of β-catenin dynamics.
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| Zhong W, Oguljahan B, Xiao Y, Nelson J, Hernandez L, Garcia-Barrio M, Francis SC.
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| Cell Signal 26(12):2765-72. doi: 10.1016/j.cellsig.2014.08.002. Epub 2014 Aug 22.
2014
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| 9 | SGK1
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| Serum-glucocorticoid regulated kinase 1 regulates macrophage recruitment and activation contributing to monocrotaline-induced pulmonary arterial hypertension.
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| Xi X, Liu S, Shi H, Yang M, Qi Y, Wang J, Du J.
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| Cardiovasc Toxicol 14(4):368-78. doi: 10.1007/s12012-014-9260-4.
2014
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| 10 | CFTR, SGK1, SHANK2
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| Serum- and glucocorticoid-induced protein kinase 1 (SGK1) increases the cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells by phosphorylating Shank2E protein.
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| Koeppen K, Coutermarsh BA, Madden DR, Stanton BA.
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| J Biol Chem 289(24):17142-50. doi: 10.1074/jbc.M114.555599. Epub 2014 May 8.
2014
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| 11 | SGK1
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| Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution.
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| Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, Whyte MK, Renshaw SA.
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| J Immunol 192(4):1796-805. doi: 10.4049/jimmunol.1300087. Epub 2014 Jan 15.
2014
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| 12 | ASPG, SGK1
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| Human 60-kDa lysophospholipase contains an N-terminal L-asparaginase domain that is allosterically regulated by L-asparagine
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| Karamitros CS, Konrad M.
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| J Biol Chem. May 9;289(19):12962-75. doi: 10.1074/jbc.M113.545038. Epub 2014 Mar 22 2014
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| 13 | KCNH2, SGK1
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| The serum- and glucocorticoid-inducible kinases SGK1 and SGK3 regulate hERG channel expression via ubiquitin ligase Nedd4-2 and GTPase Rab11.
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| Lamothe SM, Zhang S.
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| J Biol Chem 288(21):15075-84. doi: 10.1074/jbc.M113.453670. Epub 2013 Apr 15.
2013
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| 14 | SGK1
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| Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis.
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| Anacker C, Cattaneo A, Musaelyan K, Zunszain PA, Horowitz M, Molteni R, Luoni A, Calabrese F, Tansey K, Gennarelli M, Thuret S, Price J, Uher R, Riva MA, Pariante CM.
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| Proc Natl Acad Sci U S A 110(21):8708-13. doi: 10.1073/pnas.1300886110. Epub 2013 May 6.
2013
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| 15 | SGK1
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| The cell survival kinase SGK1 and its targets FOXO3a and NDRG1 in aged human brain.
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| Sahin P, McCaig C, Jeevahan J, Murray JT, Hainsworth AH.
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| Neuropathol Appl Neurobiol 39(6):623-33. doi: 10.1111/nan.12023.
2013
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| 16 | CNKSR3, NEDD4L, SCNN1A, SCNN1B, SCNN1D, SGK1
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| Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex.
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| Soundararajan R, Ziera T, Koo E, Ling K, Wang J, Borden SA, Pearce D.
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| J Biol Chem 287(39):33014-25. Epub 2012 Jul 31.
2012
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| 17 | SGK1
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| Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells.
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| Hryciw DH, Kruger WA, Briffa JF, Slattery C, Bolithon A, Lee A, Poronnik P.
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| Cell Physiol Biochem 30(5):1215-26. doi: 10.1159/000343313. Epub 2012 Oct 15.
2012
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| 18 | ORAI1, SGK1
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| Translational regulation of the serum- and glucocorticoid-inducible kinase-1 (SGK1) in platelets.
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| Pelzl L, Tolios A, Schmidt EM, Alesutan I, Walker B, Münzer P, Borst O, Gawaz M, Lang F.
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| Biochem Biophys Res Commun 425(1):1-5. doi: 10.1016/j.bbrc.2012.07.026. Epub 2012 Jul 16.
2012
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| 19 | NOTCH1, SGK1
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| Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.
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| Mo JS, Ann EJ, Yoon JH, Jung J, Choi YH, Kim HY, Ahn JS, Kim SM, Kim MY, Hong JA, Seo MS, Lang F, Choi EJ, Park HS.
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| J Cell Sci 124(Pt 1):100-12. Epub 2010 Dec 8.
2011
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| 20 | SGK1
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| Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
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| Fagerli UM, Ullrich K, Stühmer T, Holien T, Köchert K, Holt RU, Bruland O, Chatterjee M, Nogai H, Lenz G, Shaughnessy JD Jr, Mathas S, Sundan A, Bargou RC, Dörken B, Børset M, Janz M.
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| Oncogene 30(28):3198-206. doi: 10.1038/onc.2011.79. Epub 2011 Apr 11.
2011
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| 21 | GNAI3, KMT2D, SGK1
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| Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.
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| Morin RD, Mendez-Lago M, Mungall AJ, Goya R, Mungall KL, Corbett RD, Johnson NA, Severson TM, Chiu R, Field M, Jackman S, Krzywinski M, Scott DW, Trinh DL, Tamura-Wells J, Li S, Firme MR, Rogic S, Griffith M, Chan S, Yakovenko O, Meyer IM, Zhao EY, Smailus D, Moksa M, Chittaranjan S, Rimsza L, Brooks-Wilson A, Spinelli JJ, Ben-Neriah S, Meissner B, Woolcock B, Boyle M, McDonald H, Tam A, Zhao Y, Delaney A, Zeng T, Tse K, Butterfield Y, Birol I, Holt R, Schein J, Horsman DE, Moore R, Jones SJ, Connors JM, Hirst M, Gascoyne RD, Marra MA.
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| Nature 476(7360):298-303. doi: 10.1038/nature10351. 2011
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| 22 | CRTC2, MAPKAP1, SGK1
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| mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel.
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| Lu M, Wang J, Ives HE, Pearce D.
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| J Biol Chem 286(35):30647-54. doi: 10.1074/jbc.M111.257592. Epub 2011 Jul 11.
2011
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| 23 | SGK1
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| SGK1: a fine balancing act for human pregnancy.
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| Fisher SJ, Giudice LC.
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| Nat Med 17(11):1348-9. doi: 10.1038/nm.2549. No abstract available.
2011
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| 24 | SGK1, TSG22D3
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| Glucocorticoid-induced Leucine zipper 1 stimulates the epithelial sodium channel by regulating serum- and glucocorticoid-induced kinase 1 stability and subcellular localization.
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| Soundararajan R, Wang J, Melters D, Pearce D.
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| J Biol Chem 285(51):39905-13. Epub 2010 Oct 14.
2010
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| 25 | RICTOR, SGK1
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| Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.
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| Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, Wei W.
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| Mol Cell 39(5):797-808.
2010
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| 26 | SGK1, SGK2, SGK3, SLC6A19
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| The serum and glucocorticoid inducible kinases SGK1-3 stimulate the neutral amino acid transporter SLC6A19.
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| Böhmer C, Sopjani M, Klaus F, Lindner R, Laufer J, Jeyaraj S, Lang F, Palmada M.
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| Cell Physiol Biochem 25(6):723-32. doi: 10.1159/000315092. Epub 2010 May 18.
2010
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| 27 | ASPG, SGK1
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| 60kDa lysophospholipase, a new Sgk1 molecular partner involved in the regulation of ENaC
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| Menniti M, Iuliano R, Föller M, Sopjani M, Alesutan I, Mariggiò S, Nofziger C, Perri AM, Amato R, Blazer-Yost B, Corda D, Lang F, Perrotti N.
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| Cell Physiol Biochem. 26(4-5):587-96. doi: 10.1159/000322326. Epub 2010 Oct 29. 2010
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| 28 | SGK1
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| Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.
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| Amato R, D'Antona L, Porciatti G, Agosti V, Menniti M, Rinaldo C, Costa N, Bellacchio E, Mattarocci S, Fuiano G, Soddu S, Paggi MG, Lang F, Perrotti N.
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| J Mol Med 87(12):1221-39. Epub 2009 Sep 11.PMID: 19756449 2009
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| 29 | SGK1, SRC
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| Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels.
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| Yue P, Lin DH, Pan CY, Leng Q, Giebisch G, Lifton RP, Wang WH.
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| Proc Natl Acad Sci U S A 106(35):15061-6. Epub 2009 Aug 18.PMID: 19706464 2009
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| 30 | SGK1
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| The physiological impact of the serum and glucocorticoid-inducible kinase SGK1.
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| Lang F, Artunc F, Vallon V.
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| Curr Opin Nephrol Hypertens 18(5):439-48. Review.PMID: 19584721 2009
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| 31 | SGK1
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| Adaptive variation regulates the expression of the human SGK1 gene in response to stress.
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| Luca F, Kashyap S, Southard C, Zou M, Witonsky D, Di Rienzo A, Conzen SD.
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| PLoS Genet 5(5):e1000489. Epub 2009 May 22.PMID: 19461886 2009
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| 32 | SGK1
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| Regulation of a third conserved phosphorylation site in SGK1.
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| Chen W, Chen Y, Xu BE, Juang YC, Stippec S, Zhao Y, Cobb MH.
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| J Biol Chem 284(6):3453-60. Epub 2008 Dec 9.PMID: 19068477 2009
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| 33 | ASIC1, SGK1
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| A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons.
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| Arteaga MF, Coric T, Straub C, Canessa CM.
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| Proc Natl Acad Sci U S A 105(11):4459-64. Epub 2008 Mar 11. 2008
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| 34 | SGK1
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| Association of SGK1 gene polymorphisms with type 2 diabetes.
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| Schwab M, Lupescu A, Mota M, Mota E, Frey A, Simon P, Mertens PR, Floege J, Luft F, Asante-Poku S, Schaeffeler E, Lang F.
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| Cell Physiol Biochem 21(1-3):151-60. Epub 2008 Jan 16.PMID: 18209482 2008
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| 35 | SLC2A1, SLC2A4, SGK1
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| Role of SGK1 kinase in regulating glucose transport via glucose transporter GLUT4.
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| Jeyaraj S, Boehmer C, Lang F, Palmada M.
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| Biochem Biophys Res Commun 356(3):629-35. Epub 2007 Mar 12. 2007
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| 36 | TRPV6, SGK1, SGK3
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| Regulation of the epithelial calcium channel TRPV6 by the serum and glucocorticoid-inducible kinase isoforms SGK1 and SGK3.
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| Bšhmer C, Palmada M, Kenngott C, Lindner R, Klaus F, Laufer J, Lang F.
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| FEBS Lett 581(29):5586-90. Epub 2007 Nov 20. 2007
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| 37 | MTOR, SGK1, SGK3, SLC6A8
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| Stimulation of the creatine transporter SLC6A8 by the protein kinases SGK1 and SGK3.
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| Shojaiefard M, Christie DL, Lang F.
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| Biochem Biophys Res Commun 334(3):742-6. 2005
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| 38 | SGK1
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| Sgk1, a cell survival response in neurodegenerative diseases.
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| Schoenebeck B, Bader V, Zhu XR, Schmitz B, Lubbert H, Stichel CC.
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| Mol Cell Neurosci 30(2):249-64. 2005
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| 39 | SGK1
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| Genetic variance of SGK-1 is associated with blood pressure, blood pressure change over time and strength of the insulin-diastolic blood pressure relationship.
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| von Wowern F, Berglund G, Carlson J, Mansson H, Hedblad B, Melander O.
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| Kidney Int 68(5):2164-72. 2005
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| 40 | NEDD4, NEDD4L, SGK3, SGK1, SLC5A1
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| Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB.
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| Dieter M, Palmada M, Rajamanickam J, Aydin A, Busjahn A, Boehmer C, Luft FC, Lang F.
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| Obes Res 12(5):862-70. 2004
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| 41 | BSND, SGK1, SGK3
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| Regulation of CLC-Ka/barttin by the ubiquitin ligase Nedd4-2 and the serum- and glucocorticoid-dependent kinases.
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| Embark HM, Bohmer C, Palmada M, Rajamanickam J, Wyatt AW, Wallisch S, Capasso G, Waldegger P, Seyberth HW, Waldegger S, Lang F.
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| Kidney Int 66(5):1918-25. 2004
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| 42 | SGK1, SGK2, SGK3
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| Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms.
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| Embark HM, Böhmer C, Vallon V, Luft F, Lang F.
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| Pflugers Arch 445(5):601-6. Epub 2002 Dec 4.
2003
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| 43 | SGK1, SGK3
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| Cloning and mapping of a novel human Serum/Glucocorticoid regulated kinase-like gene, SGKL, to chromosome 8q12.3-q13.1.
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| Dai F, Yu L, He H, Zhao Y, Yang J, Zhang X, Zhao S.
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| Genomics 62(1):95-7 1999
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| 44 | SGK1, SGK2, SGK3
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| Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.
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| Kobayashi T, Deak M, Morrice N, Cohen P.
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| Biochem J 344 Pt 1:189-97. 1999
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| 45 | SGK1
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| Genomic organization and chromosomal localization of the human SGK protein kinase gene.
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| Waldegger S, et al.
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| Genomics 51 : 299-302. 1998
|