| 1 | SFRP5
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| Sfrp5 associates with beta-cell function in humans.
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| Carstensen-Kirberg M, Hatziagelaki E, Tsiavou A, Chounta A, Nowotny P, Pacini G, Dimitriadis G, Roden M, Herder C.
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| Eur J Clin Invest 46(6):535-43. doi: 10.1111/eci.12629. Epub 2016 Apr 30.
2016
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| 2 | SFRP5
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| Sfrp5 mediates glucose-induced proliferation in rat pancreatic β-cells.
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| Guan B, Li W, Li F, Xie Y, Ni Q, Gu Y, Li X, Wang Q, Zhang H, Ning G.
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| J Endocrinol 229(2):73-83. doi: 10.1530/JOE-15-0535. Epub 2016 Feb 11.
2016
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| 3 | SFRP5
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| Secreted Frizzled-related Protein 5 Diminishes Cardiac Inflammation and Protects the Heart from Ischemia/Reperfusion Injury.
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| Nakamura K, Sano S, Fuster JJ, Kikuchi R, Shimizu I, Ohshima K, Katanasaka Y, Ouchi N, Walsh K.
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| J Biol Chem 291(6):2566-75. doi: 10.1074/jbc.M115.693937. Epub 2015 Dec 2.
2016
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| 4 | SFRP5
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| Estrogen-inducible sFRP5 inhibits early B-lymphopoiesis in vivo, but not during pregnancy.
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| Yokota T, Oritani K, Sudo T, Ishibashi T, Doi Y, Habuchi Y, Ichii M, Fukushima K, Okuzaki D, Tomizuka K, Yamawaki K, Kakitani M, Shimono A, Morii E, Kincade PW, Kanakura Y.
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| Eur J Immunol 45(5):1390-401. doi: 10.1002/eji.201444939. Epub 2015 Mar 16.
2015
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| 5 | SFRP5
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| Inhibition of secreted frizzled-related protein 5 improves glucose metabolism.
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| Rulifson IC, Majeti JZ, Xiong Y, Hamburger A, Lee KJ, Miao L, Lu M, Gardner J, Gong Y, Wu H, Case R, Yeh WC, Richards WG, Baribault H, Li Y.
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| Am J Physiol Endocrinol Metab 307(12):E1144-52. doi: 10.1152/ajpendo.00283.2014. Epub 2014 Nov 4.
2014
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| 6 | SFRP5
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| SFRP5 acts as a mature adipocyte marker but not as a regulator in adipogenesis.
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| Wang R, Hong J, Liu R, Chen M, Xu M, Gu W, Zhang Y, Ma Q, Wang F, Shi J, Wang J, Wang W, Ning G.
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| J Mol Endocrinol 53(3):405-15. doi: 10.1530/JME-14-0037. Epub 2014 Oct 16.
2014
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| 7 | SFRP5
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| Effect of Sfrp5 on cytokine release and insulin action in primary human adipocytes and skeletal muscle cells.
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| Carstensen M, Wiza C, Röhrig K, Fahlbusch P, Roden M, Herder C, Ouwens DM.
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| PLoS One 9(1):e85906. doi: 10.1371/journal.pone.0085906. eCollection 2014.
2014
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| 8 | SFRP5
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| SFRP5 correlates with obesity and metabolic syndrome and increases after weight loss in children.
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| Tan X, Wang X, Chu H, Liu H, Yi X, Xiao Y.
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| Clin Endocrinol (Oxf) 81(3):363-9. doi: 10.1111/cen.12361. Epub 2013 Dec 12.
2014
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| 9 | IFT88, SFRP5
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| Ift88 regulates Hedgehog signaling, Sfrp5 expression, and β-catenin activity in post-natal growth plate.
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| Chang CF, Serra R.
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| J Orthop Res 31(3):350-6. doi: 10.1002/jor.22237. Epub 2012 Oct 3.
2013
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| 10 | SFRP5
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| Downregulation of Sfrp5 promotes beta cell proliferation during obesity in the rat.
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| Rebuffat SA, Oliveira JM, Altirriba J, Palau N, Garcia A, Esteban Y, Nadal B, Gomis R.
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| Diabetologia 56(11):2446-55. doi: 10.1007/s00125-013-3030-x. Epub 2013 Sep 5.
2013
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| 11 | SFRP5
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| SFRP5 inhibits gastric epithelial cell migration induced by macrophage-derived Wnt5a.
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| Zhao C, Ma H, Bu X, Wang W, Zhang N.
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| Carcinogenesis 34(1):146-52. doi: 10.1093/carcin/bgs309. Epub 2012 Oct 10.
2013
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| 12 | SFRP5
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| Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition.
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| Mori H, Prestwich TC, Reid MA, Longo KA, Gerin I, Cawthorn WP, Susulic VS, Krishnan V, Greenfield A, Macdougald OA.
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| J Clin Invest 122(7):2405-16. doi: 10.1172/JCI63604. Epub 2012 Jun 25.
2012
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| 13 | SFRP5
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| Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity.
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| Ouchi N, Higuchi A, Ohashi K, Oshima Y, Gokce N, Shibata R, Akasaki Y, Shimono A, Walsh K.
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| Science 329(5990):454-7. doi: 10.1126/science.1188280. Epub 2010 Jun 17.
2010
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| 14 | SFRP5
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| Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer.
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| Zhao C, Bu X, Zhang N, Wang W.
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| BMC Cancer 9:224. doi: 10.1186/1471-2407-9-224.
2009
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| 15 | SFRP2, SFRP5
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| Silencing of secreted frizzled-related protein genes in MSI colorectal carcinogenesis.
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| Tanaka J, Watanabe T, Kanazawa T, Tada T, Kazama Y, Tanaka T, Nagawa H.
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| Hepatogastroenterology 55(85):1265-8. 2008
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| 16 | SFRP5
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| Hypermethylation and aberrant expression of secreted frizzled-related protein genes in pancreatic cancer.
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| Bu XM, Zhao CH, Zhang N, Gao F, Lin S, Dai XW.
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| World J Gastroenterol 14(21):3421-4.
2008
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| 17 | SFRP1, SFRP2, SFRP5
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| Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.
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| Takagi H, Sasaki S, Suzuki H, Toyota M, Maruyama R, Nojima M, Yamamoto H, Omata M, Tokino T, Imai K, Shinomura Y.
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| J Gastroenterol 43(5):378-89. Epub 2008 Jul 1. 2008
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| 18 | SFRP5
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| Epigenetic inactivation of the secreted frizzled-related protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis.
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| Veeck J, Geisler C, Noetzel E, Alkaya S, Hartmann A, Knüchel R, Dahl E.
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| Carcinogenesis 29(5):991-8. Epub 2008 Mar 19.
2008
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| 19 | BCL2, DLEC1, HOXA1, HOXA10, KL, NR3C1, SEZ6L, SFRP4, SFRP5, SMAD9, TWIST1
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| DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis.
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| Kang GH, Lee S, Cho NY, Gandamihardja T, Long TI, Weisenberger DJ, Campan M, Laird PW.
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| Lab Invest 88(2):161-70. Epub 2007 Dec 24.
2008
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| 20 | SFRP1, SFRP2, SFRP5
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| Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.
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| Nojima M, Suzuki H, Toyota M, Watanabe Y, Maruyama R, Sasaki S, Sasaki Y, Mita H, Nishikawa N, Yamaguchi K, Hirata K, Itoh F, Tokino T, Mori M, Imai K, Shinomura Y.
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| Oncogene 26(32):4699-713. Epub 2007 Feb 5.
2007
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| 21 | SFRP1, SFRP2, SFRP3, SFRP5
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| SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway.
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| Shih YL, Hsieh CB, Lai HC, Yan MD, Hsieh TY, Chao YC, Lin YW.
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| Int J Cancer 121(5):1028-35.
2007
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| 22 | SFRP2, SFRP5
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| Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium.
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| Chang JT, et al.
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| Hum Mol Genet 8(4):575-83. 1999
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| 23 | SFRP1, SFRP2, SFRP5
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| SARPs : a family of secreted apoptosis-related proteins.
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| Melkonyan HS, et al.
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| Proc Natl Acad Sci U S A 94 : 13636-13641. 1997
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