Citations for
1SFRP1
Sfrp1 Modulates Cell-signaling Events Underlying Telencephalic Patterning, Growth and Differentiation.
Esteve P, Crespo I, Kaimakis P, Sandonís A, Bovolenta P.
Cereb Cortex ereb Cortex. 2018 Feb 27. doi: 10.1093/cercor/bhy013. [Epub ahead of print] 2018
2SFRP1, WNT7A
Opposite Roles of Wnt7a and Sfrp1 in Modulating Proper Development of Neural Progenitors in the Mouse Cerebral Cortex.
Miao N, Bian S, Lee T, Mubarak T, Huang S, Wen Z, Hussain G, Sun T.
Front Mol Neurosci 11:247. doi: 10.3389/fnmol.2018.00247. eCollection 2018. 2018
3SFRP1
Methylation of secreted frizzled-related protein 1 (SFRP1) promoter downregulates Wnt/β-catenin activity in keloids.
Liu J, Zhu H, Wang H, Li J, Han F, Liu Y, Zhang W, He T, Li N, Zheng Z, Hu D.
J Mol Histol 49(2):185-193. doi: 10.1007/s10735-018-9758-3. Epub 2018 Feb 17. 2018
4SFRP1
Regulation of early growth response 2 expression by secreted frizzled related protein 1.
Gregory KJ, Morin SM, Schneider SS.
BMC Cancer 17(1):473. doi: 10.1186/s12885-017-3426-y. 2017
5CBX5, SFRP1
Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression.
Cheng W, Tian L, Wang B, Qi Y, Huang W, Li H, Chen YJ.
Oncotarget 7(30):48107-48119. doi: 10.18632/oncotarget.10371. 2016
6SFRP1
Estrogen-mediated signaling is differentially affected by the expression levels of Sfrp1 in mammary epithelial cells.
Gregory KJ, Schneider SS.
Cell Biol Int 39(7):873-9. doi: 10.1002/cbin.10468. Epub 2015 May 5. 2015
7SFRP1
Loss of secreted frizzled-related protein-1 leads to deterioration of cardiac function in mice and plays a role in human cardiomyopathy.
Sklepkiewicz P, Shiomi T, Kaur R, Sun J, Kwon S, Mercer B, Bodine P, Schermuly RT, George I, Schulze PC, D'Armiento JM.
Circ Heart Fail 8(2):362-72. doi: 10.1161/CIRCHEARTFAILURE.114.001274. Epub 2015 Feb 10. 2015
8SFRP1
Clinical significance of reduced SFRP1 expression in acute myeloid leukemia.
An C, Guo H, Wen XM, Tang CY, Yang J, Zhu XW, Yin JY, Liu Q, Ma JC, Deng ZQ, Lin J, Qian J.
Leuk Lymphoma 56(7):2056-60. doi: 10.3109/10428194.2014.977883. Epub 2014 Nov 19. 2015
9FRZB, SFRP1
Immunohistochemical expression of SFRP1 and SFRP3 proteins in normal and malignant reproductive tissues of rats and humans.
Partl JZ, Fabijanovic D, Skrtic A, Vranic S, Martic TN, Serman L.
Appl Immunohistochem Mol Morphol 22(9):681-7. doi: 10.1097/PAI.0000000000000019. 2014
10SFRP1, SFRP2
Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling.
Xavier CP, Melikova M, Chuman Y, Üren A, Baljinnyam B, Rubin JS.
Cell Signal 26(1):94-101. doi: 10.1016/j.cellsig.2013.09.016. Epub 2013 Sep 28. 2014
11SFRP1
Mice deficient in Sfrp1 exhibit increased adiposity, dysregulated glucose metabolism, and enhanced macrophage infiltration.
Gauger KJ, Bassa LM, Henchey EM, Wyman J, Bentley B, Brown M, Shimono A, Schneider SS.
PLoS One 8(12):e78320. doi: 10.1371/journal.pone.0078320. eCollection 2013. 2013
12SFRP1, SFRP2
Sfrp1 and Sfrp2 are not involved in Wnt/β-catenin signal silencing during lens induction but are required for maintenance of Wnt/β-catenin signaling in lens epithelial cells.
Sugiyama Y, Shelley EJ, Wen L, Stump RJ, Shimono A, Lovicu FJ, McAvoy JW.
Dev Biol 384(2):181-93. doi: 10.1016/j.ydbio.2013.10.008. Epub 2013 Oct 16. 2013
13SFRP1
Secreted Frizzled-related protein 1 (sFRP1) regulates spermatid adhesion in the testis via dephosphorylation of focal adhesion kinase and the nectin-3 adhesion protein complex.
Wong EW, Lee WM, Cheng CY.
FASEB J 27(2):464-77. doi: 10.1096/fj.12-212514. Epub 2012 Oct 16. 2013
14DKKL1, DLX3, HR, SFRP1, SFRP2, SOSTDC1
Hairless plays a role in formation of inner root sheath via regulation of Dlx3 gene.
Kim BK, Lee HY, Choi JH, Kim JK, Yoon JB, Yoon SK.
J Biol Chem 287(20):16681-8. doi: 10.1074/jbc.M111.320770. Epub 2012 Mar 22. 2012
15SFRP1
Wnt antagonist SFRP1 functions as a secreted mediator of senescence.
Elzi DJ, Song M, Hakala K, Weintraub ST, Shiio Y.
Mol Cell Biol 32(21):4388-99. doi: 10.1128/MCB.06023-11. Epub 2012 Aug 27. 2012
16ADAM10, SFRP1, SFRP2
SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.
Esteve P, Sandonìs A, Cardozo M, Malapeira J, Ibañez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P.
Nat Neurosci 14(5):562-9. Epub 2011 Apr 10. 2011
17SFRP1
Secreted-frizzled related protein 1 is a transcriptional repression target of the t(8;21) fusion protein in acute myeloid leukemia.
Cheng CK, Li L, Cheng SH, Ng K, Chan NP, Ip RK, Wong RS, Shing MM, Li CK, Ng MH.
Blood 118(25):6638-48. doi: 10.1182/blood-2011-05-354712. Epub 2011 Oct 26. 2011
18BNC1, COL14A1, COL15A1, CST6, GREM1, PDLIM4, RPRM, SFRP1
Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma.
Morris MR, Ricketts C, Gentle D, Abdulrahman M, Clarke N, Brown M, Kishida T, Yao M, Latif F, Maher ER.
Oncogene ncogene. 2010 Feb 15. [Epub ahead of print]PMID: 20154727 2010
19APC, CTNNB1, DISC1, DLG4, FZD1, GSK3B, NEUROD1, PRICKLE1, SFRP1, SYN1, WNT1, WNT3, WNT3A, WNT5A, WNT7A
Emerging roles of Wnts in the adult nervous system.
Inestrosa NC, Arenas E.
Nat Rev Neurosci. 11(2):77-86. 2010
20FZD7, SFRP1
Expression profile of WNT, FZD and sFRP genes in human hematopoietic cells.
Sercan Z, Pehlivan M, Sercan HO.
Leuk Res 34(7):946-9. doi: 10.1016/j.leukres.2010.02.009. Epub 2010 Mar 6. 2010
21SFRP1, SFRP2
SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway.
Chung MT, Lai HC, Sytwu HK, Yan MD, Shih YL, Chang CC, Yu MH, Liu HS, Chu DW, Lin YW.
Gynecol Oncol 112(3):646-53. Epub 2008 Dec 18. 2009
22SFRP1
Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers.
Yang ZQ, Liu G, Bollig-Fischer A, Haddad R, Tarca AL, Ethier SP.
Int J Cancer 125(7):1613-21. 2009
23SFRP1, SFRP2
Wnt modulators, SFRP-1, and SFRP-2 are expressed in osteoblasts and differentially regulate hematopoietic stem cells.
Nakajima H, Ito M, Morikawa Y, Komori T, Fukuchi Y, Shibata F, Okamoto S, Kitamura T.
Biochem Biophys Res Commun 390(1):65-70. Epub 2009 Sep 22. 2009
24SFRP1, SFRP2, SFRP5
Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.
Takagi H, Sasaki S, Suzuki H, Toyota M, Maruyama R, Nojima M, Yamamoto H, Omata M, Tokino T, Imai K, Shinomura Y.
J Gastroenterol 43(5):378-89. Epub 2008 Jul 1. 2008
25SFRP1
Methylation-associated silencing of SFRP1 in renal cell carcinoma.
Awakura Y, Nakamura E, Ito N, Kamoto T, Ogawa O.
Oncol Rep 20(5):1257-63. 2008
26SFRP1, SFRP2, SFRP5
Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.
Nojima M, Suzuki H, Toyota M, Watanabe Y, Maruyama R, Sasaki S, Sasaki Y, Mita H, Nishikawa N, Yamaguchi K, Hirata K, Itoh F, Tokino T, Mori M, Imai K, Shinomura Y.
Oncogene 26(32):4699-713. Epub 2007 Feb 5. 2007
27SFRP1, SFRP2, SFRP3, SFRP5
SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway.
Shih YL, Hsieh CB, Lai HC, Yan MD, Hsieh TY, Chao YC, Lin YW.
Int J Cancer 121(5):1028-35. 2007
28SFRP1
Frequent loss of SFRP1 expression in multiple human solid tumours: association with aberrant promoter methylation in renal cell carcinoma.
Dahl E, Wiesmann F, Woenckhaus M, Stoehr R, Wild PJ, Veeck J, Knüchel R, Klopocki E, Sauter G, Simon R, Wieland WF, Walter B, Denzinger S, Hartmann A, Hammerschmied CG.
Oncogene 26(38):5680-91. Epub 2007 Mar 12. 2007
29SFRP1
Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function.
Bhat RA, Stauffer B, Komm BS, Bodine PV.
J Cell Biochem 102(6):1519-28.PMID: 17471511 2007
30SFRP1
Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis.
Veeck J, Niederacher D, An H, Klopocki E, Wiesmann F, Betz B, Galm O, Camara O, DŸrst M, Kristiansen G, Huszka C, KnŸchel R, Dahl E.
Oncogene 25(24):3479-88. Epub 2006 Jan 30. 2006
31SFRP1
Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-small-cell lung cancer.
Fukui T, Kondo M, Ito G, Maeda O, Sato N, Yoshioka H, Yokoi K, Ueda Y, Shimokata K, Sekido Y.
Oncogene 24(41):6323-7. 2005
32SFRP1
SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor.
Rodriguez J, Esteve P, Weinl C, Ruiz JM, Fermin Y, Trousse F, Dwivedy A, Holt C, Bovolenta P.
Nat Neurosci 8(10):1301-9. Epub 2005 Sep 18. 2005
33CEP63, EIF4G2, SFRP1
The transcripts of SFRP1,CEP63 and EIF4G2 genes are frequently downregulated in transitional cell carcinomas of the bladder.
Buim ME, Soares FA, Sarkis AS, Nagai MA.
Oncology 69(6):445-54. Epub 2006 Jan 12. 2005
34SFRP1
Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors.
Klopocki E, Kristiansen G, Wild PJ, Klaman I, Castanos-Velez E, Singer G, Stohr R, Simon R, Sauter G, Leibiger H, Essers L, Weber B, Hermann K, Rosenthal A, Hartmann A, Dahl E.
Int J Oncol 25(3):641-9. 2004
35SFRP1
Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers.
Takada T, Yagi Y, Maekita T, Imura M, Nakagawa S, Tsao SW, Miyamoto K, Yoshino O, Yasugi T, Taketani Y, Ushijima T.
Cancer Sci 95(9):741-4. 2004
36SFRP1
SFRP1 modulates retina cell differentiation through a beta-catenin-independent mechanism.
Esteve P, Trousse F, Rodríguez J, Bovolenta P.
J Cell Sci. 116(Pt 12):2471-81. 2003
37FAM127A, LPHN2, SEZ6L, SFRP1, SFRP4
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer.
Suzuki H, Gabrielson E, Chen W, Anbazhagan R, van Engeland M, Weijenberg MP, Herman JG, Baylin SB.
Nat Genet 31(2):141-9. 2002
38SFRP1
Secreted Frizzled-related proteins can regulate metanephric development.
Yoshino K, Rubin JS, Higinbotham KG, Uren A, Anest V, Plisov SY, Perantoni AO.
Mech Dev. 102(1-2):45-55. 2001
39FGFR1, SFRP1
Differential expression assay of chromosome arm 8p genes identifies Frizzled-related (FRP1/FRZB) and Fibroblast Growth Factor Receptor 1 (FGFR1) as candidate breast cancer genes.
Ugolini F, et al.
Oncogene 18(10):1903-10. 1999
40SFRP1, WNT1
Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling.
Bafico A, Gazit A, Pramila T, Finch PW, Yaniv A, Aaronson SA.
J Biol Chem. 274(23):16180-7. 1999
41SFRP1, SFRP2, FRZB, SFRP4
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.
Rattner A, et al.
Proc Natl Acad Sci U S A 94 : 2859-2863. 1997
42SFRP1, SFRP2, SFRP5
SARPs : a family of secreted apoptosis-related proteins.
Melkonyan HS, et al.
Proc Natl Acad Sci U S A 94 : 13636-13641. 1997
43SFRP1
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.
Finch PW, He X, Kelley MJ, Uren A, Schaudies RP, Popescu NC, Rudikoff S, Aaronson SA, Varmus HE, Rubin JS.
Proc Natl Acad Sci U S A. 94(13):6770-5. 1997
44FZD2, FZD9, SFRP1, SFRP2, FZD8
A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.
Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J.
J Biol Chem 271(8):4468-76. 1996