| 1 | SFRP1
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| Sfrp1 Modulates Cell-signaling Events Underlying Telencephalic Patterning, Growth and Differentiation.
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| Esteve P, Crespo I, Kaimakis P, Sandonís A, Bovolenta P.
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| Cereb Cortex ereb Cortex. 2018 Feb 27. doi: 10.1093/cercor/bhy013. [Epub ahead of print]
2018
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| 2 | SFRP1, WNT7A
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| Opposite Roles of Wnt7a and Sfrp1 in Modulating Proper Development of Neural Progenitors in the Mouse Cerebral Cortex.
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| Miao N, Bian S, Lee T, Mubarak T, Huang S, Wen Z, Hussain G, Sun T.
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| Front Mol Neurosci 11:247. doi: 10.3389/fnmol.2018.00247. eCollection 2018.
2018
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| 3 | SFRP1
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| Methylation of secreted frizzled-related protein 1 (SFRP1) promoter downregulates Wnt/β-catenin activity in keloids.
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| Liu J, Zhu H, Wang H, Li J, Han F, Liu Y, Zhang W, He T, Li N, Zheng Z, Hu D.
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| J Mol Histol 49(2):185-193. doi: 10.1007/s10735-018-9758-3. Epub 2018 Feb 17.
2018
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| 4 | SFRP1
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| Regulation of early growth response 2 expression by secreted frizzled related protein 1.
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| Gregory KJ, Morin SM, Schneider SS.
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| BMC Cancer 17(1):473. doi: 10.1186/s12885-017-3426-y.
2017
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| 5 | CBX5, SFRP1
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| Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression.
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| Cheng W, Tian L, Wang B, Qi Y, Huang W, Li H, Chen YJ.
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| Oncotarget 7(30):48107-48119. doi: 10.18632/oncotarget.10371.
2016
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| 6 | SFRP1
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| Estrogen-mediated signaling is differentially affected by the expression levels of Sfrp1 in mammary epithelial cells.
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| Gregory KJ, Schneider SS.
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| Cell Biol Int 39(7):873-9. doi: 10.1002/cbin.10468. Epub 2015 May 5.
2015
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| 7 | SFRP1
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| Loss of secreted frizzled-related protein-1 leads to deterioration of cardiac function in mice and plays a role in human cardiomyopathy.
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| Sklepkiewicz P, Shiomi T, Kaur R, Sun J, Kwon S, Mercer B, Bodine P, Schermuly RT, George I, Schulze PC, D'Armiento JM.
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| Circ Heart Fail 8(2):362-72. doi: 10.1161/CIRCHEARTFAILURE.114.001274. Epub 2015 Feb 10.
2015
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| 8 | SFRP1
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| Clinical significance of reduced SFRP1 expression in acute myeloid leukemia.
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| An C, Guo H, Wen XM, Tang CY, Yang J, Zhu XW, Yin JY, Liu Q, Ma JC, Deng ZQ, Lin J, Qian J.
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| Leuk Lymphoma 56(7):2056-60. doi: 10.3109/10428194.2014.977883. Epub 2014 Nov 19.
2015
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| 9 | FRZB, SFRP1
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| Immunohistochemical expression of SFRP1 and SFRP3 proteins in normal and malignant reproductive tissues of rats and humans.
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| Partl JZ, Fabijanovic D, Skrtic A, Vranic S, Martic TN, Serman L.
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| Appl Immunohistochem Mol Morphol 22(9):681-7. doi: 10.1097/PAI.0000000000000019.
2014
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| 10 | SFRP1, SFRP2
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| Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling.
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| Xavier CP, Melikova M, Chuman Y, Üren A, Baljinnyam B, Rubin JS.
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| Cell Signal 26(1):94-101. doi: 10.1016/j.cellsig.2013.09.016. Epub 2013 Sep 28.
2014
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| 11 | SFRP1
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| Mice deficient in Sfrp1 exhibit increased adiposity, dysregulated glucose metabolism, and enhanced macrophage infiltration.
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| Gauger KJ, Bassa LM, Henchey EM, Wyman J, Bentley B, Brown M, Shimono A, Schneider SS.
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| PLoS One 8(12):e78320. doi: 10.1371/journal.pone.0078320. eCollection 2013.
2013
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| 12 | SFRP1, SFRP2
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| Sfrp1 and Sfrp2 are not involved in Wnt/β-catenin signal silencing during lens induction but are required for maintenance of Wnt/β-catenin signaling in lens epithelial cells.
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| Sugiyama Y, Shelley EJ, Wen L, Stump RJ, Shimono A, Lovicu FJ, McAvoy JW.
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| Dev Biol 384(2):181-93. doi: 10.1016/j.ydbio.2013.10.008. Epub 2013 Oct 16.
2013
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| 13 | SFRP1
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| Secreted Frizzled-related protein 1 (sFRP1) regulates spermatid adhesion in the testis via dephosphorylation of focal adhesion kinase and the nectin-3 adhesion protein complex.
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| Wong EW, Lee WM, Cheng CY.
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| FASEB J 27(2):464-77. doi: 10.1096/fj.12-212514. Epub 2012 Oct 16.
2013
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| 14 | DKKL1, DLX3, HR, SFRP1, SFRP2, SOSTDC1
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| Hairless plays a role in formation of inner root sheath via regulation of Dlx3 gene.
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| Kim BK, Lee HY, Choi JH, Kim JK, Yoon JB, Yoon SK.
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| J Biol Chem 287(20):16681-8. doi: 10.1074/jbc.M111.320770. Epub 2012 Mar 22.
2012
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| 15 | SFRP1
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| Wnt antagonist SFRP1 functions as a secreted mediator of senescence.
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| Elzi DJ, Song M, Hakala K, Weintraub ST, Shiio Y.
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| Mol Cell Biol 32(21):4388-99. doi: 10.1128/MCB.06023-11. Epub 2012 Aug 27.
2012
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| 16 | ADAM10, SFRP1, SFRP2
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| SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.
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| Esteve P, Sandonìs A, Cardozo M, Malapeira J, Ibañez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P.
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| Nat Neurosci 14(5):562-9. Epub 2011 Apr 10.
2011
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| 17 | SFRP1
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| Secreted-frizzled related protein 1 is a transcriptional repression target of the t(8;21) fusion protein in acute myeloid leukemia.
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| Cheng CK, Li L, Cheng SH, Ng K, Chan NP, Ip RK, Wong RS, Shing MM, Li CK, Ng MH.
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| Blood 118(25):6638-48. doi: 10.1182/blood-2011-05-354712. Epub 2011 Oct 26.
2011
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| 18 | BNC1, COL14A1, COL15A1, CST6, GREM1, PDLIM4, RPRM, SFRP1
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| Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma.
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| Morris MR, Ricketts C, Gentle D, Abdulrahman M, Clarke N, Brown M, Kishida T, Yao M, Latif F, Maher ER.
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| Oncogene ncogene. 2010 Feb 15. [Epub ahead of print]PMID: 20154727 2010
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| 19 | APC, CTNNB1, DISC1, DLG4, FZD1, GSK3B, NEUROD1, PRICKLE1, SFRP1, SYN1, WNT1, WNT3, WNT3A, WNT5A, WNT7A
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| Emerging roles of Wnts in the adult nervous system.
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| Inestrosa NC, Arenas E.
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| Nat Rev Neurosci. 11(2):77-86. 2010
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| 20 | FZD7, SFRP1
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| Expression profile of WNT, FZD and sFRP genes in human hematopoietic cells.
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| Sercan Z, Pehlivan M, Sercan HO.
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| Leuk Res 34(7):946-9. doi: 10.1016/j.leukres.2010.02.009. Epub 2010 Mar 6.
2010
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| 21 | SFRP1, SFRP2
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| SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway.
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| Chung MT, Lai HC, Sytwu HK, Yan MD, Shih YL, Chang CC, Yu MH, Liu HS, Chu DW, Lin YW.
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| Gynecol Oncol 112(3):646-53. Epub 2008 Dec 18. 2009
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| 22 | SFRP1
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| Methylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancers.
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| Yang ZQ, Liu G, Bollig-Fischer A, Haddad R, Tarca AL, Ethier SP.
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| Int J Cancer 125(7):1613-21.
2009
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| 23 | SFRP1, SFRP2
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| Wnt modulators, SFRP-1, and SFRP-2 are expressed in osteoblasts and differentially regulate hematopoietic stem cells.
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| Nakajima H, Ito M, Morikawa Y, Komori T, Fukuchi Y, Shibata F, Okamoto S, Kitamura T.
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| Biochem Biophys Res Commun 390(1):65-70. Epub 2009 Sep 22.
2009
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| 24 | SFRP1, SFRP2, SFRP5
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| Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.
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| Takagi H, Sasaki S, Suzuki H, Toyota M, Maruyama R, Nojima M, Yamamoto H, Omata M, Tokino T, Imai K, Shinomura Y.
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| J Gastroenterol 43(5):378-89. Epub 2008 Jul 1. 2008
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| 25 | SFRP1
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| Methylation-associated silencing of SFRP1 in renal cell carcinoma.
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| Awakura Y, Nakamura E, Ito N, Kamoto T, Ogawa O.
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| Oncol Rep 20(5):1257-63.
2008
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| 26 | SFRP1, SFRP2, SFRP5
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| Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.
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| Nojima M, Suzuki H, Toyota M, Watanabe Y, Maruyama R, Sasaki S, Sasaki Y, Mita H, Nishikawa N, Yamaguchi K, Hirata K, Itoh F, Tokino T, Mori M, Imai K, Shinomura Y.
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| Oncogene 26(32):4699-713. Epub 2007 Feb 5.
2007
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| 27 | SFRP1, SFRP2, SFRP3, SFRP5
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| SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway.
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| Shih YL, Hsieh CB, Lai HC, Yan MD, Hsieh TY, Chao YC, Lin YW.
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| Int J Cancer 121(5):1028-35.
2007
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| 28 | SFRP1
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| Frequent loss of SFRP1 expression in multiple human solid tumours: association with aberrant promoter methylation in renal cell carcinoma.
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| Dahl E, Wiesmann F, Woenckhaus M, Stoehr R, Wild PJ, Veeck J, Knüchel R, Klopocki E, Sauter G, Simon R, Wieland WF, Walter B, Denzinger S, Hartmann A, Hammerschmied CG.
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| Oncogene 26(38):5680-91. Epub 2007 Mar 12.
2007
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| 29 | SFRP1
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| Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function.
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| Bhat RA, Stauffer B, Komm BS, Bodine PV.
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| J Cell Biochem 102(6):1519-28.PMID: 17471511 2007
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| 30 | SFRP1
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| Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis.
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| Veeck J, Niederacher D, An H, Klopocki E, Wiesmann F, Betz B, Galm O, Camara O, DŸrst M, Kristiansen G, Huszka C, KnŸchel R, Dahl E.
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| Oncogene 25(24):3479-88. Epub 2006 Jan 30. 2006
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| 31 | SFRP1
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| Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-small-cell lung cancer.
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| Fukui T, Kondo M, Ito G, Maeda O, Sato N, Yoshioka H, Yokoi K, Ueda Y, Shimokata K, Sekido Y.
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| Oncogene 24(41):6323-7. 2005
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| 32 | SFRP1
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| SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor.
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| Rodriguez J, Esteve P, Weinl C, Ruiz JM, Fermin Y, Trousse F, Dwivedy A, Holt C, Bovolenta P.
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| Nat Neurosci 8(10):1301-9. Epub 2005 Sep 18. 2005
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| 33 | CEP63, EIF4G2, SFRP1
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| The transcripts of SFRP1,CEP63 and EIF4G2 genes are frequently downregulated in transitional cell carcinomas of the bladder.
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| Buim ME, Soares FA, Sarkis AS, Nagai MA.
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| Oncology 69(6):445-54. Epub 2006 Jan 12.
2005
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| 34 | SFRP1
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| Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors.
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| Klopocki E, Kristiansen G, Wild PJ, Klaman I, Castanos-Velez E, Singer G, Stohr R, Simon R, Sauter G, Leibiger H, Essers L, Weber B, Hermann K, Rosenthal A, Hartmann A, Dahl E.
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| Int J Oncol 25(3):641-9. 2004
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| 35 | SFRP1
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| Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers.
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| Takada T, Yagi Y, Maekita T, Imura M, Nakagawa S, Tsao SW, Miyamoto K, Yoshino O, Yasugi T, Taketani Y, Ushijima T.
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| Cancer Sci 95(9):741-4. 2004
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| 36 | SFRP1
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| SFRP1 modulates retina cell differentiation through a beta-catenin-independent mechanism.
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| Esteve P, Trousse F, Rodríguez J, Bovolenta P.
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| J Cell Sci. 116(Pt 12):2471-81. 2003
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| 37 | FAM127A, LPHN2, SEZ6L, SFRP1, SFRP4
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| A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer.
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| Suzuki H, Gabrielson E, Chen W, Anbazhagan R, van Engeland M, Weijenberg MP, Herman JG, Baylin SB.
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| Nat Genet 31(2):141-9. 2002
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| 38 | SFRP1
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| Secreted Frizzled-related proteins can regulate metanephric development.
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| Yoshino K, Rubin JS, Higinbotham KG, Uren A, Anest V, Plisov SY, Perantoni AO.
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| Mech Dev. 102(1-2):45-55. 2001
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| 39 | FGFR1, SFRP1
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| Differential expression assay of chromosome arm 8p genes identifies Frizzled-related (FRP1/FRZB) and Fibroblast Growth Factor Receptor 1 (FGFR1) as candidate breast cancer genes.
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| Ugolini F, et al.
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| Oncogene 18(10):1903-10. 1999
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| 40 | SFRP1, WNT1
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| Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling.
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| Bafico A, Gazit A, Pramila T, Finch PW, Yaniv A, Aaronson SA.
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| J Biol Chem. 274(23):16180-7. 1999
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| 41 | SFRP1, SFRP2, FRZB, SFRP4
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| A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.
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| Rattner A, et al.
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| Proc Natl Acad Sci U S A 94 : 2859-2863. 1997
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| 42 | SFRP1, SFRP2, SFRP5
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| SARPs : a family of secreted apoptosis-related proteins.
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| Melkonyan HS, et al.
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| Proc Natl Acad Sci U S A 94 : 13636-13641. 1997
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| 43 | SFRP1
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| Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.
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| Finch PW, He X, Kelley MJ, Uren A, Schaudies RP, Popescu NC, Rudikoff S, Aaronson SA, Varmus HE, Rubin JS.
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| Proc Natl Acad Sci U S A. 94(13):6770-5. 1997
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| 44 | FZD2, FZD9, SFRP1, SFRP2, FZD8
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| A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.
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| Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J.
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| J Biol Chem 271(8):4468-76. 1996
|