Citations for
Maspin, the molecular bridge between the plasminogen activator system and beta1 integrin that facilitates cell adhesion.
Endsley MP, Hu Y, Deng Y, He X, Warejcka DJ, Twining SS, Gonias SL, Zhang M.
J Biol Chem 286(28):24599-607. Epub 2011 May 23. 2011
Interaction of testisin with maspin and its impact on invasion and cell death resistance of cervical cancer cells.
Yeom SY, Jang HL, Lee SJ, Kim E, Son HJ, Kim BG, Park C.
FEBS Lett 584(8):1469-75. Epub 2010 Mar 6. 2010
High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer.
Jiang R, Xia Y, Li J, Deng L, Zhao L, Shi J, Wang X, Sun B.
Int J Cancer 126(5):1263-74. 2010
BRCA1 185delAG mutant protein, BRAt, up-regulates maspin in ovarian epithelial cells.
O'Donnell JD, Linger RJ, Kruk PA.
Gynecol Oncol 116(2):262-8. Epub 2009 Nov 10. 2010
Mammaglobin and maspin transcripts in blood may reflect disease progression and the effect of therapy in breast cancer.
Bitisik O, Saip P, Saglam S, Derin D, Dalay N.
Genet Mol Res 9(1):97-106. 2010
Maspin (SERPINB5) is an obligate intracellular serpin.
Teoh SS, Whisstock JC, Bird PI.
J Biol Chem 285(14):10862-9. Epub 2010 Feb 1. 2010
Maspin regulates endothelial cell adhesion and migration through an integrin signaling pathway.
Qin L, Zhang M.
J Biol Chem 285(42):32360-9. Epub 2010 Aug 16. 2010
G-helix of maspin mediates effects on cell migration and adhesion.
Ravenhill L, Wagstaff L, Edwards DR, Ellis V, Bass R.
J Biol Chem 285(47):36285-92. Epub 2010 Sep 13. 2010
Loss of maspin is a negative prognostic factor for invasion and metastasis in oral squamous cell carcinoma.
Yoshizawa K, Nozaki S, Okamune A, Kitahara H, Ohara T, Kato K, Kawashiri S, Yamamoto E.
J Oral Pathol Med 38(6):535-9. Epub 2009 Mar 13. 2009
Nuclear, compared with combined nuclear and cytoplasmic expression of maspin, is linked in lung adenocarcinoma to reduced VEGF-A levels and in Stage I, improved survival.
Frey A, Soubani AO, Adam AK, Sheng S, Pass HI, Lonardo F.
Histopathology 54(5):590-7. Epub 2009 Mar 20. 2009
PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cells.
Eitel JA, Bijangi-Vishehsaraei K, Saadatzadeh MR, Bhavsar JR, Murphy MP, Pollok KE, Mayo LD.
Cell Cycle 8(6):896-901. Epub 2009 Mar 21. 2009
[Expression of maspin and its relation to tumor vascularization in epithelian ovarian cancer]
Ma Y, Peng ZL.
Sichuan Da Xue Xue Bao Yi Xue Ban 40(2):223-7. Chinese. 2009
The effect of aberrant maspin expression on the invasive ability of pancreatic ductal adenocarcinoma cells.
Hong SN, Lee JK, Choe WH, Ha HY, Park K, Sung IK, Lee KT, Kim JJ, Rhee JC.
Oncol Rep 21(2):425-30. 2009
Maspin reduces prostate cancer metastasis to bone.
Hall DC, Johnson-Pais TL, Grubbs B, Bernal R, Leach RJ, Padalecki SS.
Urol Oncol 26(6):652-8. Epub 2008 Jan 15. 2008
Cytoplasmic and nuclear maspin expression in lung carcinomas: an immunohistochemical study using tissue microarrays.
Zheng HC, Saito H, Masuda S, Wang ZG, Takano Y.
Appl Immunohistochem Mol Morphol 16(5):459-65. 2008
Maspin polymorphism associated with apoptosis susceptibility and in vivo tumorigenesis.
Jang HL, Nam E, Lee KH, Yeom S, Son HJ, Park C.
Int J Mol Med 22(3):333-8. 2008
Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin.
Luo JL, Tan W, Ricono JM, Korchynskyi O, Zhang M, Gonias SL, Cheresh DA, Karin M.
Nature 446(7136):690-4. Epub 2007 Mar 18. Erratum in: Nature. 2009 Feb 12;457(7231):920. 2007
Correlation of serpin-protease expression by comparative analysis of real-time PCR profiling data.
Badola S, Spurling H, Robison K, Fedyk ER, Silverman GA, Strayle J, Kapeller R, Tsu CA.
Genomics 88(2):173-84. Epub 2006 May 18. 2006
Gene expression profiles in human gastric cancer: expression of maspin correlates with lymph node metastasis.
Terashima M, Maesawa C, Oyama K, Ohtani S, Akiyama Y, Ogasawara S, Takagane A, Saito K, Masuda T, Kanzaki N, Matsuyama S, Hoshino Y, Kogure M, Gotoh M, Shirane M, Mori K.
Br J Cancer 92(6):1130-6. 2005
Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
Sugimoto S, Maass N, Takimoto Y, Sato K, Minei S, Zhang M, Hoshikawa Y, Junemann KP, Jonat W, Nagasaki K.
Cancer Lett 203(2):209-15. 2004
Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling.
Sato N, Fukushima N, Matsubayashi H, Goggins M.
Oncogene 23(8):1531-8. 2004
Maspin expression in normal lung and non-small-cell lung cancers: cellular property-associated expression under the control of promoter DNA methylation.
Yatabe Y, Mitsudomi T, Takahashi T.
Oncogene 23(23):4041-9. 2004
Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis.
Cher ML, Biliran HR Jr, Bhagat S, Meng Y, Che M, Lockett J, Abrams J, Fridman R, Zachareas M, Sheng S.
Proc Natl Acad Sci U S A 100(13):7847-52. Epub 2003 Jun 03. 2003
Silencing of the maspin gene by promoter hypermethylation in thyroid cancer.
Boltze C, Schneider-Stock R, Quednow C, Hinze R, Mawrin C, Hribaschek A, Roessner A, Hoang-Vu C.
Int J Mol Med 12(4):479-84. 2003
Maspin - the most commonly-expressed gene of the 18q21.3 serpin cluster in lung cancer - is strongly expressed in preneoplastic bronchial lesions.
Smith SL, Watson SG, Ratschiller D, Gugger M, Betticher DC, Heighway J.
Oncogene 22(54):8677-87. 2003
Expression and regulation of tumor suppressor gene maspin in breast cancer.
Maass N, Nagasaki K, Ziebart M, Mundhenke C, Jonat W.
Clin Breast Cancer 3(4):281-7. 2002
Maspin is up-regulated in premalignant prostate epithelia.
Pierson CR, McGowen R, Grignon D, Sakr W, Dey J, Sheng S.
Prostate 53(4):255-62. 2002
Cardiac phosphodiesterase 5 (cGMP-specific) modulates beta-adrenergic signaling in vivo and is down-regulated in heart failure.
Senzaki H, Smith CJ, Juang GJ, Isoda T, Mayer SP, Ohler A, Paolocci N, Tomaselli GF, Hare JM, Kass DA.
FASEB J 15(10):1718-26. 2001
Maspin: synthesis by human cornea and regulation of in vitro stromal cell adhesion to extracellular matrix.
Ngamkitidechakul C, Burke JM, O'Brien WJ, Twining SS.
Invest Ophthalmol Vis Sci 42(13):3135-41. 2001
p53 regulates the expression of the tumor suppressor gene maspin.
Zou Z, Gao C, Nagaich AK, Connell T, Saito S, Moul JW, Seth P, Appella E, Srivastava S.
J Biol Chem 275(9):6051-4. 2000
High tumoral maspin expression is associated with improved survival of patients with oral squamous cell carcinoma.
Xia W, Lau YK, Hu MC, Li L, Johnston DA, Sheng Sj, El-Naggar A, Hung MC.
Oncogene 19(20):2398-403. 2000
Maspin--a novel protease inhibitor with tumor-suppressing activity in breast cancer.
Maass N, Hojo T, Zhang M, Sager R, Jonat W, Nagasaki K.
Acta Oncol 39(8):931-4. Review. 2000
Tissue-type plasminogen activator is a target of the tumor suppressor gene maspin.
Sheng S, Truong B, Fredrickson D, Wu R, Pardee AB, Sager R.
Proc Natl Acad Sci U S A 95(2):499-504. 1998
Maspin suppresses the invasive phenotype of human breast carcinoma.
Seftor RE, et al.
Cancer Res 58 : 5681-5685. 1998
Maspin : a tumor suppressing serpin.
Sager R, et al.
Curr Top Microbiol Immunol 213 : 51-64. 1996
A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. (serpins/maspin/plasminogen activator inhibitor type 2).
Schneider SS, et al.
Proc Natl Acad Sci U S A 92 : 3147-3151. 1995
Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells.
Zou Z, et al.
Science 263 : 526-529. 1994