| 1 | ITGB1, PLAUR, SERPINB5
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| Maspin, the molecular bridge between the plasminogen activator system and beta1 integrin that facilitates cell adhesion.
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| Endsley MP, Hu Y, Deng Y, He X, Warejcka DJ, Twining SS, Gonias SL, Zhang M.
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| J Biol Chem 286(28):24599-607. Epub 2011 May 23.
2011
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| 2 | PRSS21, SERPINB5
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| Interaction of testisin with maspin and its impact on invasion and cell death resistance of cervical cancer cells.
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| Yeom SY, Jang HL, Lee SJ, Kim E, Son HJ, Kim BG, Park C.
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| FEBS Lett 584(8):1469-75. Epub 2010 Mar 6.
2010
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| 3 | CHUK, IKBKG, SERPINB5
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| High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer.
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| Jiang R, Xia Y, Li J, Deng L, Zhao L, Shi J, Wang X, Sun B.
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| Int J Cancer 126(5):1263-74. 2010
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| 4 | BRCA1, SERPINB5
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| BRCA1 185delAG mutant protein, BRAt, up-regulates maspin in ovarian epithelial cells.
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| O'Donnell JD, Linger RJ, Kruk PA.
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| Gynecol Oncol 116(2):262-8. Epub 2009 Nov 10.
2010
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| 5 | SERPINB5
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| Mammaglobin and maspin transcripts in blood may reflect disease progression and the effect of therapy in breast cancer.
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| Bitisik O, Saip P, Saglam S, Derin D, Dalay N.
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| Genet Mol Res 9(1):97-106.
2010
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| 6 | SERPINB5
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| Maspin (SERPINB5) is an obligate intracellular serpin.
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| Teoh SS, Whisstock JC, Bird PI.
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| J Biol Chem 285(14):10862-9. Epub 2010 Feb 1.
2010
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| 7 | SERPINB5
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| Maspin regulates endothelial cell adhesion and migration through an integrin signaling pathway.
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| Qin L, Zhang M.
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| J Biol Chem 285(42):32360-9. Epub 2010 Aug 16.
2010
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| 8 | SERPINB5
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| G-helix of maspin mediates effects on cell migration and adhesion.
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| Ravenhill L, Wagstaff L, Edwards DR, Ellis V, Bass R.
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| J Biol Chem 285(47):36285-92. Epub 2010 Sep 13.
2010
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| 9 | SERPINB5
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| Loss of maspin is a negative prognostic factor for invasion and metastasis in oral squamous cell carcinoma.
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| Yoshizawa K, Nozaki S, Okamune A, Kitahara H, Ohara T, Kato K, Kawashiri S, Yamamoto E.
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| J Oral Pathol Med 38(6):535-9. Epub 2009 Mar 13.
2009
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| 10 | SERPINB5
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| Nuclear, compared with combined nuclear and cytoplasmic expression of maspin, is linked in lung adenocarcinoma to reduced VEGF-A levels and in Stage I, improved survival.
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| Frey A, Soubani AO, Adam AK, Sheng S, Pass HI, Lonardo F.
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| Histopathology 54(5):590-7. Epub 2009 Mar 20.
2009
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| 11 | SERPINB5
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| PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cells.
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| Eitel JA, Bijangi-Vishehsaraei K, Saadatzadeh MR, Bhavsar JR, Murphy MP, Pollok KE, Mayo LD.
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| Cell Cycle 8(6):896-901. Epub 2009 Mar 21.
2009
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| 12 | SERPINB5
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| [Expression of maspin and its relation to tumor vascularization in epithelian ovarian cancer]
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| Ma Y, Peng ZL.
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| Sichuan Da Xue Xue Bao Yi Xue Ban 40(2):223-7. Chinese.
2009
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| 13 | SERPINB5
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| The effect of aberrant maspin expression on the invasive ability of pancreatic ductal adenocarcinoma cells.
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| Hong SN, Lee JK, Choe WH, Ha HY, Park K, Sung IK, Lee KT, Kim JJ, Rhee JC.
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| Oncol Rep 21(2):425-30.
2009
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| 14 | SERPINB5
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| Maspin reduces prostate cancer metastasis to bone.
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| Hall DC, Johnson-Pais TL, Grubbs B, Bernal R, Leach RJ, Padalecki SS.
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| Urol Oncol 26(6):652-8. Epub 2008 Jan 15.
2008
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| 15 | SERPINB5
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| Cytoplasmic and nuclear maspin expression in lung carcinomas: an immunohistochemical study using tissue microarrays.
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| Zheng HC, Saito H, Masuda S, Wang ZG, Takano Y.
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| Appl Immunohistochem Mol Morphol 16(5):459-65.
2008
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| 16 | SERPINB5
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| Maspin polymorphism associated with apoptosis susceptibility and in vivo tumorigenesis.
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| Jang HL, Nam E, Lee KH, Yeom S, Son HJ, Park C.
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| Int J Mol Med 22(3):333-8.
2008
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| 17 | SERPINB5
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| Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin.
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| Luo JL, Tan W, Ricono JM, Korchynskyi O, Zhang M, Gonias SL, Cheresh DA, Karin M.
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| Nature 446(7136):690-4. Epub 2007 Mar 18. Erratum in: Nature. 2009 Feb 12;457(7231):920.
2007
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| 18 | SERPINI2, SERPINA1, SERPINB1, SERPINB5, SERPINB8, SERPINB4, TMPRSS3
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| Correlation of serpin-protease expression by comparative analysis of real-time PCR profiling data.
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| Badola S, Spurling H, Robison K, Fedyk ER, Silverman GA, Strayle J, Kapeller R, Tsu CA.
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| Genomics 88(2):173-84. Epub 2006 May 18. 2006
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| 19 | SERPINB5
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| Gene expression profiles in human gastric cancer: expression of maspin correlates with lymph node metastasis.
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| Terashima M, Maesawa C, Oyama K, Ohtani S, Akiyama Y, Ogasawara S, Takagane A, Saito K, Masuda T, Kanzaki N, Matsuyama S, Hoshino Y, Kogure M, Gotoh M, Shirane M, Mori K.
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| Br J Cancer 92(6):1130-6. 2005
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| 20 | SERPINB5
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| Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
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| Sugimoto S, Maass N, Takimoto Y, Sato K, Minei S, Zhang M, Hoshikawa Y, Junemann KP, Jonat W, Nagasaki K.
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| Cancer Lett 203(2):209-15. 2004
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| 21 | S100P, SERPINB5
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| Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling.
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| Sato N, Fukushima N, Matsubayashi H, Goggins M.
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| Oncogene 23(8):1531-8. 2004
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| 22 | SERPINB5
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| Maspin expression in normal lung and non-small-cell lung cancers: cellular property-associated expression under the control of promoter DNA methylation.
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| Yatabe Y, Mitsudomi T, Takahashi T.
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| Oncogene 23(23):4041-9. 2004
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| 23 | SERPINB5
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| Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis.
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| Cher ML, Biliran HR Jr, Bhagat S, Meng Y, Che M, Lockett J, Abrams J, Fridman R, Zachareas M, Sheng S.
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| Proc Natl Acad Sci U S A 100(13):7847-52. Epub 2003 Jun 03. 2003
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| 24 | SERPINB5
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| Silencing of the maspin gene by promoter hypermethylation in thyroid cancer.
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| Boltze C, Schneider-Stock R, Quednow C, Hinze R, Mawrin C, Hribaschek A, Roessner A, Hoang-Vu C.
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| Int J Mol Med 12(4):479-84. 2003
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| 25 | SERPINB5
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| Maspin - the most commonly-expressed gene of the 18q21.3 serpin cluster in lung cancer - is strongly expressed in preneoplastic bronchial lesions.
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| Smith SL, Watson SG, Ratschiller D, Gugger M, Betticher DC, Heighway J.
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| Oncogene 22(54):8677-87. 2003
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| 26 | SERPINB5
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| Expression and regulation of tumor suppressor gene maspin in breast cancer.
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| Maass N, Nagasaki K, Ziebart M, Mundhenke C, Jonat W.
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| Clin Breast Cancer 3(4):281-7. 2002
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| 27 | SERPINB5
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| Maspin is up-regulated in premalignant prostate epithelia.
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| Pierson CR, McGowen R, Grignon D, Sakr W, Dey J, Sheng S.
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| Prostate 53(4):255-62. 2002
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| 28 | PDE5A, SERPINB5
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| Cardiac phosphodiesterase 5 (cGMP-specific) modulates beta-adrenergic signaling in vivo and is down-regulated in heart failure.
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| Senzaki H, Smith CJ, Juang GJ, Isoda T, Mayer SP, Ohler A, Paolocci N, Tomaselli GF, Hare JM, Kass DA.
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| FASEB J 15(10):1718-26. 2001
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| 29 | SERPINB5
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| Maspin: synthesis by human cornea and regulation of in vitro stromal cell adhesion to extracellular matrix.
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| Ngamkitidechakul C, Burke JM, O'Brien WJ, Twining SS.
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| Invest Ophthalmol Vis Sci 42(13):3135-41.
2001
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| 30 | SERPINB5
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| p53 regulates the expression of the tumor suppressor gene maspin.
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| Zou Z, Gao C, Nagaich AK, Connell T, Saito S, Moul JW, Seth P, Appella E, Srivastava S.
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| J Biol Chem 275(9):6051-4. 2000
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| 31 | SERPINB5
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| High tumoral maspin expression is associated with improved survival of patients with oral squamous cell carcinoma.
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| Xia W, Lau YK, Hu MC, Li L, Johnston DA, Sheng Sj, El-Naggar A, Hung MC.
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| Oncogene 19(20):2398-403. 2000
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| 32 | SERPINB5
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| Maspin--a novel protease inhibitor with tumor-suppressing activity in breast cancer.
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| Maass N, Hojo T, Zhang M, Sager R, Jonat W, Nagasaki K.
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| Acta Oncol 39(8):931-4. Review. 2000
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| 33 | SERPINB5, PLAT
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| Tissue-type plasminogen activator is a target of the tumor suppressor gene maspin.
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| Sheng S, Truong B, Fredrickson D, Wu R, Pardee AB, Sager R.
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| Proc Natl Acad Sci U S A 95(2):499-504. 1998
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| 34 | SERPINB5
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| Maspin suppresses the invasive phenotype of human breast carcinoma.
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| Seftor RE, et al.
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| Cancer Res 58 : 5681-5685. 1998
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| 35 | SERPINB5
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| Maspin : a tumor suppressing serpin.
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| Sager R, et al.
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| Curr Top Microbiol Immunol 213 : 51-64. 1996
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| 36 | SERPINB5, SERPINB2, SERPINB3, SERPINB4, SPI@2
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| A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. (serpins/maspin/plasminogen activator inhibitor type 2).
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| Schneider SS, et al.
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| Proc Natl Acad Sci U S A 92 : 3147-3151. 1995
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| 37 | SERPINB5
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| Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells.
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| Zou Z, et al.
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| Science 263 : 526-529. 1994
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